PT3668856T - Novos compostos de tetrazole e sua utilização no tratamento de tuberculose - Google Patents

Novos compostos de tetrazole e sua utilização no tratamento de tuberculose

Info

Publication number
PT3668856T
PT3668856T PT187558150T PT18755815T PT3668856T PT 3668856 T PT3668856 T PT 3668856T PT 187558150 T PT187558150 T PT 187558150T PT 18755815 T PT18755815 T PT 18755815T PT 3668856 T PT3668856 T PT 3668856T
Authority
PT
Portugal
Prior art keywords
tuberculosis
treatment
tetrazole compounds
novel tetrazole
novel
Prior art date
Application number
PT187558150T
Other languages
English (en)
Portuguese (pt)
Original Assignee
Glaxosmithkline Ip Dev Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Glaxosmithkline Ip Dev Ltd filed Critical Glaxosmithkline Ip Dev Ltd
Publication of PT3668856T publication Critical patent/PT3668856T/pt

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/4427—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
    • A61K31/4439—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems containing a five-membered ring with nitrogen as a ring hetero atom, e.g. omeprazole
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A61P31/06—Antibacterial agents for tuberculosis
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D249/00—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms
    • C07D249/02—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms not condensed with other rings
    • C07D249/04—1,2,3-Triazoles; Hydrogenated 1,2,3-triazoles
    • C07D249/06—1,2,3-Triazoles; Hydrogenated 1,2,3-triazoles with aryl radicals directly attached to ring atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D257/00—Heterocyclic compounds containing rings having four nitrogen atoms as the only ring hetero atoms
    • C07D257/02—Heterocyclic compounds containing rings having four nitrogen atoms as the only ring hetero atoms not condensed with other rings
    • C07D257/04—Five-membered rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/06—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pulmonology (AREA)
  • Communicable Diseases (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Oncology (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
PT187558150T 2017-08-17 2018-08-16 Novos compostos de tetrazole e sua utilização no tratamento de tuberculose PT3668856T (pt)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP17382574 2017-08-17

Publications (1)

Publication Number Publication Date
PT3668856T true PT3668856T (pt) 2021-09-15

Family

ID=59713960

Family Applications (1)

Application Number Title Priority Date Filing Date
PT187558150T PT3668856T (pt) 2017-08-17 2018-08-16 Novos compostos de tetrazole e sua utilização no tratamento de tuberculose

Country Status (19)

Country Link
US (1) US11072591B2 (enExample)
EP (1) EP3668856B1 (enExample)
JP (1) JP7410017B2 (enExample)
KR (1) KR102661367B1 (enExample)
CN (1) CN110997651B (enExample)
AU (1) AU2018317812C1 (enExample)
CA (1) CA3072854A1 (enExample)
CY (1) CY1124577T1 (enExample)
DK (1) DK3668856T3 (enExample)
ES (1) ES2885573T3 (enExample)
HR (1) HRP20211326T1 (enExample)
HU (1) HUE055732T2 (enExample)
LT (1) LT3668856T (enExample)
PL (1) PL3668856T3 (enExample)
PT (1) PT3668856T (enExample)
RS (1) RS62267B1 (enExample)
SI (1) SI3668856T1 (enExample)
SM (1) SMT202100515T1 (enExample)
WO (1) WO2019034729A1 (enExample)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN111184718A (zh) * 2018-11-15 2020-05-22 鲁南制药集团股份有限公司 法罗培南在制备治疗初治病原学阳性肺结核药物中的用途
CN115403533B (zh) * 2021-05-28 2023-08-25 永康市第一人民医院 一种1-苯乙烯基-1,2,3-三氮唑化合物及其制备方法和应用
CN116102483B (zh) * 2021-11-09 2025-01-17 中国医学科学院药物研究所 取代吡咯-2,5-二酮类化合物及其制备方法和用途
CN116726018A (zh) * 2023-08-02 2023-09-12 上海市肺科医院(上海市职业病防治院) 一种贝达喹啉、德拉马尼、氯法齐明和吡嗪酰胺的联用和应用
CN117379430B (zh) * 2023-10-11 2026-07-21 深圳市第三人民医院(深圳市肝病研究所) 一种地拉韦啶的用途

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ID24105A (id) 1997-07-22 2000-07-06 Shionogi & Co Komposisi untuk mengobati atau mencegah glomerulopati
JP2010523599A (ja) 2007-04-05 2010-07-15 シーメンス メディカル ソリューションズ ユーエスエー インコーポレイテッド クリックケミストリーを使用した炭酸脱水酵素−ixのための分子イメージングプローブの開発
WO2017066964A1 (en) 2015-10-22 2017-04-27 Merck Sharp & Dohme Corp. Oxazolidinone compounds and methods of use thereof as antibacterial agents

Also Published As

Publication number Publication date
CA3072854A1 (en) 2019-02-21
PL3668856T3 (pl) 2021-12-13
SI3668856T1 (sl) 2021-11-30
US20200231555A1 (en) 2020-07-23
KR102661367B1 (ko) 2024-04-29
BR112020003247A2 (pt) 2020-08-18
CN110997651B (zh) 2023-01-03
CN110997651A (zh) 2020-04-10
RS62267B1 (sr) 2021-09-30
LT3668856T (lt) 2021-09-27
RU2020110818A3 (enExample) 2021-10-11
KR20200041915A (ko) 2020-04-22
AU2018317812C1 (en) 2021-08-26
EP3668856B1 (en) 2021-06-23
CY1124577T1 (el) 2022-07-22
JP7410017B2 (ja) 2024-01-09
AU2018317812A1 (en) 2020-02-20
AU2018317812B2 (en) 2021-04-15
HUE055732T2 (hu) 2021-12-28
RU2020110818A (ru) 2021-09-17
ES2885573T3 (es) 2021-12-14
US11072591B2 (en) 2021-07-27
EP3668856A1 (en) 2020-06-24
HRP20211326T1 (hr) 2021-11-26
WO2019034729A1 (en) 2019-02-21
JP2020531425A (ja) 2020-11-05
DK3668856T3 (da) 2021-09-20
SMT202100515T1 (it) 2021-11-12

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