PL3668856T3 - Nowe związki tetrazolu i ich zastosowanie w leczeniu gruźlicy - Google Patents

Nowe związki tetrazolu i ich zastosowanie w leczeniu gruźlicy

Info

Publication number
PL3668856T3
PL3668856T3 PL18755815T PL18755815T PL3668856T3 PL 3668856 T3 PL3668856 T3 PL 3668856T3 PL 18755815 T PL18755815 T PL 18755815T PL 18755815 T PL18755815 T PL 18755815T PL 3668856 T3 PL3668856 T3 PL 3668856T3
Authority
PL
Poland
Prior art keywords
tuberculosis
treatment
tetrazole compounds
novel tetrazole
novel
Prior art date
Application number
PL18755815T
Other languages
English (en)
Inventor
Carlos Alemparte-Gallardo
Lourdes ENCINAS
Jorge ESQUIVIAS PROVENCIO
Original Assignee
Glaxosmithkline Intellectual Property Development Limited
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Glaxosmithkline Intellectual Property Development Limited filed Critical Glaxosmithkline Intellectual Property Development Limited
Publication of PL3668856T3 publication Critical patent/PL3668856T3/pl

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D257/00Heterocyclic compounds containing rings having four nitrogen atoms as the only ring hetero atoms
    • C07D257/02Heterocyclic compounds containing rings having four nitrogen atoms as the only ring hetero atoms not condensed with other rings
    • C07D257/04Five-membered rings
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/4427Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
    • A61K31/4439Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems containing a five-membered ring with nitrogen as a ring hetero atom, e.g. omeprazole
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents
    • A61P31/06Antibacterial agents for tuberculosis
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D249/00Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms
    • C07D249/02Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms not condensed with other rings
    • C07D249/041,2,3-Triazoles; Hydrogenated 1,2,3-triazoles
    • C07D249/061,2,3-Triazoles; Hydrogenated 1,2,3-triazoles with aryl radicals directly attached to ring atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D401/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/06Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D403/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/06Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D405/00Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/06Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Epidemiology (AREA)
  • Pulmonology (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
PL18755815T 2017-08-17 2018-08-16 Nowe związki tetrazolu i ich zastosowanie w leczeniu gruźlicy PL3668856T3 (pl)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP17382574 2017-08-17
PCT/EP2018/072205 WO2019034729A1 (en) 2017-08-17 2018-08-16 NOVEL TETRAZOLE COMPOUNDS AND THEIR USE IN THE TREATMENT OF TUBERCULOSIS
EP18755815.0A EP3668856B1 (en) 2017-08-17 2018-08-16 Novel tetrazole compounds and their use in the treatment of tuberculosis

Publications (1)

Publication Number Publication Date
PL3668856T3 true PL3668856T3 (pl) 2021-12-13

Family

ID=59713960

Family Applications (1)

Application Number Title Priority Date Filing Date
PL18755815T PL3668856T3 (pl) 2017-08-17 2018-08-16 Nowe związki tetrazolu i ich zastosowanie w leczeniu gruźlicy

Country Status (19)

Country Link
US (1) US11072591B2 (pl)
EP (1) EP3668856B1 (pl)
JP (1) JP7410017B2 (pl)
KR (1) KR102661367B1 (pl)
CN (1) CN110997651B (pl)
AU (1) AU2018317812C1 (pl)
CA (1) CA3072854A1 (pl)
CY (1) CY1124577T1 (pl)
DK (1) DK3668856T3 (pl)
ES (1) ES2885573T3 (pl)
HR (1) HRP20211326T1 (pl)
HU (1) HUE055732T2 (pl)
LT (1) LT3668856T (pl)
PL (1) PL3668856T3 (pl)
PT (1) PT3668856T (pl)
RS (1) RS62267B1 (pl)
SI (1) SI3668856T1 (pl)
SM (1) SMT202100515T1 (pl)
WO (1) WO2019034729A1 (pl)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN111184718A (zh) * 2018-11-15 2020-05-22 鲁南制药集团股份有限公司 法罗培南在制备治疗初治病原学阳性肺结核药物中的用途
CN115403533B (zh) * 2021-05-28 2023-08-25 永康市第一人民医院 一种1-苯乙烯基-1,2,3-三氮唑化合物及其制备方法和应用
CN116102483B (zh) * 2021-11-09 2025-01-17 中国医学科学院药物研究所 取代吡咯-2,5-二酮类化合物及其制备方法和用途
CN116726018A (zh) * 2023-08-02 2023-09-12 上海市肺科医院(上海市职业病防治院) 一种贝达喹啉、德拉马尼、氯法齐明和吡嗪酰胺的联用和应用

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1029541B1 (en) * 1997-07-22 2006-03-22 Shionogi & Co., Ltd. Therapeutic or prophylactic agent for glomerulopathy
WO2008124703A2 (en) * 2007-04-05 2008-10-16 Siemens Medical Solutions Usa, Inc. Development of molecular imaging probes for carbonic anhydrase-ix using click chemistry
WO2017066964A1 (en) 2015-10-22 2017-04-27 Merck Sharp & Dohme Corp. Oxazolidinone compounds and methods of use thereof as antibacterial agents

Also Published As

Publication number Publication date
WO2019034729A1 (en) 2019-02-21
EP3668856B1 (en) 2021-06-23
LT3668856T (lt) 2021-09-27
HRP20211326T1 (hr) 2021-11-26
AU2018317812C1 (en) 2021-08-26
ES2885573T3 (es) 2021-12-14
CN110997651A (zh) 2020-04-10
AU2018317812A1 (en) 2020-02-20
HUE055732T2 (hu) 2021-12-28
RS62267B1 (sr) 2021-09-30
SMT202100515T1 (it) 2021-11-12
BR112020003247A2 (pt) 2020-08-18
DK3668856T3 (da) 2021-09-20
EP3668856A1 (en) 2020-06-24
AU2018317812B2 (en) 2021-04-15
US11072591B2 (en) 2021-07-27
RU2020110818A3 (pl) 2021-10-11
CN110997651B (zh) 2023-01-03
CA3072854A1 (en) 2019-02-21
JP2020531425A (ja) 2020-11-05
KR102661367B1 (ko) 2024-04-29
SI3668856T1 (sl) 2021-11-30
CY1124577T1 (el) 2022-07-22
PT3668856T (pt) 2021-09-15
KR20200041915A (ko) 2020-04-22
RU2020110818A (ru) 2021-09-17
JP7410017B2 (ja) 2024-01-09
US20200231555A1 (en) 2020-07-23

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