CY1124577T1 - Καινοτομες ενωσεις τετραζολιου και η χρηση τους στη θεραπεια της φυματιωσης - Google Patents

Καινοτομες ενωσεις τετραζολιου και η χρηση τους στη θεραπεια της φυματιωσης

Info

Publication number
CY1124577T1
CY1124577T1 CY20211100770T CY211100770T CY1124577T1 CY 1124577 T1 CY1124577 T1 CY 1124577T1 CY 20211100770 T CY20211100770 T CY 20211100770T CY 211100770 T CY211100770 T CY 211100770T CY 1124577 T1 CY1124577 T1 CY 1124577T1
Authority
CY
Cyprus
Prior art keywords
treatment
tuberculosis
tetrazole compounds
novel tetrazole
novel
Prior art date
Application number
CY20211100770T
Other languages
English (en)
Inventor
Carlos Alemparte-Gallardo
Lourdes ENCINAS
Jorge ESQUIVIAS PROVENCIO
Original Assignee
Glaxosmithkline Intellectual Property Development Limited
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Glaxosmithkline Intellectual Property Development Limited filed Critical Glaxosmithkline Intellectual Property Development Limited
Publication of CY1124577T1 publication Critical patent/CY1124577T1/el

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D257/00—Heterocyclic compounds containing rings having four nitrogen atoms as the only ring hetero atoms
    • C07D257/02—Heterocyclic compounds containing rings having four nitrogen atoms as the only ring hetero atoms not condensed with other rings
    • C07D257/04—Five-membered rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D249/00—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms
    • C07D249/02—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms not condensed with other rings
    • C07D249/04—1,2,3-Triazoles; Hydrogenated 1,2,3-triazoles
    • C07D249/06—1,2,3-Triazoles; Hydrogenated 1,2,3-triazoles with aryl radicals directly attached to ring atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/4427—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
    • A61K31/4439—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems containing a five-membered ring with nitrogen as a ring hetero atom, e.g. omeprazole
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A61P31/06—Antibacterial agents for tuberculosis
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/06—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pulmonology (AREA)
  • Communicable Diseases (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Oncology (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)

Abstract

Η εφεύρεση σχετίζεται με μία ένωση του Τύπου (Ι) ή ένα φαρμακευτικώς αποδεκτό άλας αυτής και με τη χρήση τους στη θεραπεία, για παράδειγμα στη θεραπεία μυκοβακτηριακών λοιμώξεων ή στη θεραπεία νόσων που προκαλούνται από μυκοβακτήριο, όπως η φυματίωση.
CY20211100770T 2017-08-17 2021-08-31 Καινοτομες ενωσεις τετραζολιου και η χρηση τους στη θεραπεια της φυματιωσης CY1124577T1 (el)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP17382574 2017-08-17
PCT/EP2018/072205 WO2019034729A1 (en) 2017-08-17 2018-08-16 NOVEL TETRAZOLE COMPOUNDS AND THEIR USE IN THE TREATMENT OF TUBERCULOSIS

Publications (1)

Publication Number Publication Date
CY1124577T1 true CY1124577T1 (el) 2022-07-22

Family

ID=59713960

Family Applications (1)

Application Number Title Priority Date Filing Date
CY20211100770T CY1124577T1 (el) 2017-08-17 2021-08-31 Καινοτομες ενωσεις τετραζολιου και η χρηση τους στη θεραπεια της φυματιωσης

Country Status (19)

Country Link
US (1) US11072591B2 (el)
EP (1) EP3668856B1 (el)
JP (1) JP7410017B2 (el)
KR (1) KR102661367B1 (el)
CN (1) CN110997651B (el)
AU (1) AU2018317812C1 (el)
BR (1) BR112020003247A2 (el)
CA (1) CA3072854A1 (el)
CY (1) CY1124577T1 (el)
DK (1) DK3668856T3 (el)
ES (1) ES2885573T3 (el)
HR (1) HRP20211326T1 (el)
HU (1) HUE055732T2 (el)
LT (1) LT3668856T (el)
PL (1) PL3668856T3 (el)
PT (1) PT3668856T (el)
RS (1) RS62267B1 (el)
SI (1) SI3668856T1 (el)
WO (1) WO2019034729A1 (el)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN111184718A (zh) * 2018-11-15 2020-05-22 鲁南制药集团股份有限公司 法罗培南在制备治疗初治病原学阳性肺结核药物中的用途
CN115403533B (zh) * 2021-05-28 2023-08-25 永康市第一人民医院 一种1-苯乙烯基-1,2,3-三氮唑化合物及其制备方法和应用

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ID29293A (id) 1997-07-22 1999-01-28 Shionogi & Co KOMPOSISI UNTUK MENGOBATI ATAU MENCEGAH GLOMERULOPATI (Pecahan dari No. W20000054)
CN101679318A (zh) * 2007-04-05 2010-03-24 美国西门子医疗解决公司 使用链接化学法的用于碳酸酐酶-ix的分子成象探针的发展
WO2017066964A1 (en) 2015-10-22 2017-04-27 Merck Sharp & Dohme Corp. Oxazolidinone compounds and methods of use thereof as antibacterial agents

Also Published As

Publication number Publication date
HUE055732T2 (hu) 2021-12-28
EP3668856B1 (en) 2021-06-23
AU2018317812A1 (en) 2020-02-20
JP7410017B2 (ja) 2024-01-09
EP3668856A1 (en) 2020-06-24
KR20200041915A (ko) 2020-04-22
RU2020110818A3 (el) 2021-10-11
US20200231555A1 (en) 2020-07-23
KR102661367B1 (ko) 2024-04-29
RU2020110818A (ru) 2021-09-17
BR112020003247A2 (pt) 2020-08-18
CN110997651A (zh) 2020-04-10
JP2020531425A (ja) 2020-11-05
PT3668856T (pt) 2021-09-15
PL3668856T3 (pl) 2021-12-13
WO2019034729A1 (en) 2019-02-21
CN110997651B (zh) 2023-01-03
LT3668856T (lt) 2021-09-27
US11072591B2 (en) 2021-07-27
SI3668856T1 (sl) 2021-11-30
HRP20211326T1 (hr) 2021-11-26
DK3668856T3 (da) 2021-09-20
RS62267B1 (sr) 2021-09-30
ES2885573T3 (es) 2021-12-14
CA3072854A1 (en) 2019-02-21
AU2018317812C1 (en) 2021-08-26
AU2018317812B2 (en) 2021-04-15

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