PT3636753T - Método de fabrico de uma célula eucariótica editada por um adn - Google Patents

Método de fabrico de uma célula eucariótica editada por um adn

Info

Publication number
PT3636753T
PT3636753T PT188128375T PT18812837T PT3636753T PT 3636753 T PT3636753 T PT 3636753T PT 188128375 T PT188128375 T PT 188128375T PT 18812837 T PT18812837 T PT 18812837T PT 3636753 T PT3636753 T PT 3636753T
Authority
PT
Portugal
Prior art keywords
edited
eukaryotic cell
kit used
manufacturing dna
dna
Prior art date
Application number
PT188128375T
Other languages
English (en)
Original Assignee
Univ Osaka
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=64566087&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=PT3636753(T) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Univ Osaka filed Critical Univ Osaka
Publication of PT3636753T publication Critical patent/PT3636753T/pt

Links

Classifications

    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
    • A01K67/00—Rearing or breeding animals, not otherwise provided for; New or modified breeds of animals
    • A01K67/027—New or modified breeds of vertebrates
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/87—Introduction of foreign genetic material using processes not otherwise provided for, e.g. co-transformation
    • C12N15/90—Stable introduction of foreign DNA into chromosome
    • C12N15/902—Stable introduction of foreign DNA into chromosome using homologous recombination
    • C12N15/907—Stable introduction of foreign DNA into chromosome using homologous recombination in mammalian cells
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/10—Processes for the isolation, preparation or purification of DNA or RNA
    • C12N15/102—Mutagenizing nucleic acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K48/00—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/80—Vectors or expression systems specially adapted for eukaryotic hosts for fungi
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/82—Vectors or expression systems specially adapted for eukaryotic hosts for plant cells, e.g. plant artificial chromosomes (PACs)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/82—Vectors or expression systems specially adapted for eukaryotic hosts for plant cells, e.g. plant artificial chromosomes (PACs)
    • C12N15/8201—Methods for introducing genetic material into plant cells, e.g. DNA, RNA, stable or transient incorporation, tissue culture methods adapted for transformation
    • C12N15/8213—Targeted insertion of genes into the plant genome by homologous recombination
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/85—Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/85—Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
    • C12N15/8509—Vectors or expression systems specially adapted for eukaryotic hosts for animal cells for producing genetically modified animals, e.g. transgenic
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/10—Cells modified by introduction of foreign genetic material
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/10—Cells modified by introduction of foreign genetic material
    • C12N5/12—Fused cells, e.g. hybridomas
    • C12N5/14—Plant cells
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/10—Cells modified by introduction of foreign genetic material
    • C12N5/12—Fused cells, e.g. hybridomas
    • C12N5/16—Animal cells
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/16—Hydrolases (3) acting on ester bonds (3.1)
    • C12N9/22—Ribonucleases RNAses, DNAses
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C07K2319/01—Fusion polypeptide containing a localisation/targetting motif
    • C07K2319/09—Fusion polypeptide containing a localisation/targetting motif containing a nuclear localisation signal
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2310/00—Structure or type of the nucleic acid
    • C12N2310/10—Type of nucleic acid
    • C12N2310/20—Type of nucleic acid involving clustered regularly interspaced short palindromic repeats [CRISPRs]
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2800/00—Nucleic acids vectors
    • C12N2800/22—Vectors comprising a coding region that has been codon optimised for expression in a respective host
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2800/00—Nucleic acids vectors
    • C12N2800/80—Vectors containing sites for inducing double-stranded breaks, e.g. meganuclease restriction sites

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Zoology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Organic Chemistry (AREA)
  • Wood Science & Technology (AREA)
  • Biotechnology (AREA)
  • Biomedical Technology (AREA)
  • General Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Microbiology (AREA)
  • Biophysics (AREA)
  • Plant Pathology (AREA)
  • Physics & Mathematics (AREA)
  • Cell Biology (AREA)
  • Medicinal Chemistry (AREA)
  • Mycology (AREA)
  • Environmental Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Botany (AREA)
  • Biodiversity & Conservation Biology (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Animal Husbandry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Public Health (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Breeding Of Plants And Reproduction By Means Of Culturing (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Coloring Foods And Improving Nutritive Qualities (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
PT188128375T 2017-06-08 2018-06-08 Método de fabrico de uma célula eucariótica editada por um adn PT3636753T (pt)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP2017113747 2017-06-08

Publications (1)

Publication Number Publication Date
PT3636753T true PT3636753T (pt) 2024-04-23

Family

ID=64566087

Family Applications (1)

Application Number Title Priority Date Filing Date
PT188128375T PT3636753T (pt) 2017-06-08 2018-06-08 Método de fabrico de uma célula eucariótica editada por um adn

Country Status (15)

Country Link
US (3) US11807869B2 (pt)
EP (2) EP4349973A3 (pt)
JP (6) JP6480647B1 (pt)
KR (1) KR102541398B1 (pt)
CN (2) CN110770342B (pt)
AU (1) AU2018279457B2 (pt)
BR (1) BR112019025717A2 (pt)
CA (1) CA3066599A1 (pt)
DK (1) DK3636753T5 (pt)
EA (1) EA201992795A1 (pt)
ES (1) ES2980050T3 (pt)
FI (1) FI3636753T3 (pt)
MX (1) MX2019014497A (pt)
PT (1) PT3636753T (pt)
WO (1) WO2018225858A1 (pt)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US11807869B2 (en) 2017-06-08 2023-11-07 Osaka University Method for producing DNA-edited eukaryotic cell, and kit used in the same
MX2020001998A (es) * 2017-08-21 2020-10-05 Univ Tokushima Tecnología de alteración específica de secuencia objetivo utilizando reconocimiento de objetivos del nucleotído.
SG11202009319YA (en) 2018-03-26 2020-10-29 Univ Kobe Nat Univ Corp Method for modifying target site in double-stranded dna in cell
WO2020122104A1 (ja) * 2018-12-11 2020-06-18 国立大学法人京都大学 ゲノムｄｎａに欠失を誘導する方法
SG11202109550TA (en) 2019-03-07 2021-09-29 Univ Columbia Rna-guided dna integration using tn7-like transposons
WO2020184723A1 (ja) * 2019-03-14 2020-09-17 国立大学法人徳島大学 Ｃｒｉｓｐｒタイプｉ－ｄシステムを利用した標的配列改変技術
US20220186263A1 (en) 2019-04-05 2022-06-16 Osaka University Method for producing knock-in cell
US11008557B1 (en) * 2019-12-18 2021-05-18 Inscripta, Inc. Cascade/dCas3 complementation assays for in vivo detection of nucleic acid-guided nuclease edited cells
BR112022013752A2 (pt) 2020-01-24 2022-10-11 C4U Corp Método para detecção de dna específico na amostra
WO2021251493A1 (ja) * 2020-06-12 2021-12-16 国立研究開発法人産業技術総合研究所 卵白タンパク質遺伝子における目的タンパク質をコードする遺伝子がノックインされた家禽細胞またはその製造方法
US20230416709A1 (en) 2020-11-06 2023-12-28 Editforce, Inc. Foki nuclease domain mutant
JPWO2022186063A1 (pt) 2021-03-01 2022-09-09
US20240229081A1 (en) * 2021-05-26 2024-07-11 The Regents Of The University Of Michigan Crispr-cas3 systems for targeted genome engineering
CN113549650B (zh) * 2021-07-05 2023-05-09 天津协和生物科技开发有限公司 一种CRISPR-SaCas9基因编辑系统及其应用
CN115595330B (zh) * 2021-07-12 2024-08-02 中国科学院微生物研究所 一种CRISPR-Cas3系统及其在抗植物病毒方面的应用
WO2024204287A1 (ja) * 2023-03-27 2024-10-03 国立大学法人京都大学 修飾ヌクレオチドを有するｃｒＲＮＡ

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB201122458D0 (en) * 2011-12-30 2012-02-08 Univ Wageningen Modified cascade ribonucleoproteins and uses thereof
EP4286402A3 (en) * 2012-12-12 2024-02-14 The Broad Institute, Inc. Crispr-cas component systems, methods and compositions for sequence manipulation
CA2944978C (en) 2014-04-08 2024-02-13 North Carolina State University Methods and compositions for rna-directed repression of transcription using crispr-associated genes
CN109536474A (zh) * 2015-06-18 2019-03-29 布罗德研究所有限公司 降低脱靶效应的crispr酶突变
JP6780860B2 (ja) * 2015-09-09 2020-11-04 国立大学法人神戸大学 標的化したｄｎａ配列の核酸塩基を特異的に変換するゲノム配列の改変方法及びそれに用いる分子複合体
WO2017066497A2 (en) * 2015-10-13 2017-04-20 Duke University Genome engineering with type i crispr systems in eukaryotic cells
US20190323038A1 (en) * 2016-06-17 2019-10-24 Montana State Univesity Bidirectional targeting for genome editing
US11807869B2 (en) 2017-06-08 2023-11-07 Osaka University Method for producing DNA-edited eukaryotic cell, and kit used in the same
MX2020001998A (es) * 2017-08-21 2020-10-05 Univ Tokushima Tecnología de alteración específica de secuencia objetivo utilizando reconocimiento de objetivos del nucleotído.
CN107557378A (zh) * 2017-09-19 2018-01-09 安徽大学 一种基于I型CRISPR‑Cas系统中基因cas7‑3的真核基因编辑方法
CN107557373A (zh) * 2017-09-19 2018-01-09 安徽大学 一种基于I‑B型CRISPR‑Cas系统基因cas3的基因编辑方法
CN113528408B (zh) * 2021-06-08 2022-03-01 湖北大学 一种基于CRISPR-nCas3系统的高效基因组大片段删除方法及应用

Also Published As

Publication number Publication date
JP2023054185A (ja) 2023-04-13
US20200102580A1 (en) 2020-04-02
EA201992795A1 (ru) 2020-04-21
JP7430358B2 (ja) 2024-02-13
CN110770342B (zh) 2023-11-17
FI3636753T3 (fi) 2024-05-03
US20240117381A1 (en) 2024-04-11
DK3636753T3 (da) 2024-05-06
MX2019014497A (es) 2020-10-12
JPWO2018225858A1 (ja) 2019-06-27
AU2018279457A1 (en) 2019-12-05
US11807869B2 (en) 2023-11-07
JP7301332B2 (ja) 2023-07-03
CA3066599A1 (en) 2018-12-13
BR112019025717A2 (pt) 2020-09-01
JP2024028649A (ja) 2024-03-04
EP4349973A2 (en) 2024-04-10
EP3636753A4 (en) 2021-03-31
JP6480647B1 (ja) 2019-03-13
EP3636753A1 (en) 2020-04-15
EP3636753B1 (en) 2024-04-03
AU2018279457B2 (en) 2024-02-15
DK3636753T5 (da) 2024-08-26
US20240124898A1 (en) 2024-04-18
JP2019062922A (ja) 2019-04-25
ES2980050T3 (es) 2024-09-27
JP2019062921A (ja) 2019-04-25
CN117778466A (zh) 2024-03-29
KR20200015700A (ko) 2020-02-12
KR102541398B1 (ko) 2023-06-07
JP2019062923A (ja) 2019-04-25
EP4349973A3 (en) 2024-06-26
WO2018225858A1 (ja) 2018-12-13
CN110770342A (zh) 2020-02-07

Similar Documents

Publication Publication Date Title
PT3636753T (pt) Método de fabrico de uma célula eucariótica editada por um adn
ZA202006500B (en) Materials and methods for engineering cells and uses thereof in immuno-oncology
IL279157A (en) Circular RNA for translation in eukaryotic cells
PL3346520T3 (pl) Ogniwo akumulatorowe i sposób jego wytwarzania
SG11202004116QA (en) T cell manufacturing compositions and methods
EP3396771A4 (en) ELECTROLYTE FOR NONAQUEOUS ELECTROLYTE BATTERY AND NONAQUEOUS ELECTROLYTE BATTERY IN WHICH THE SAME IS USED
SG11202004081YA (en) Improvements in structural cells, matrices and methods of assembly
SG11202005062SA (en) Electrochemical methods, devices and compositions
PL3261166T3 (pl) Elektrolit do niewodnego ogniwa elektrolitowego i ogniwo z niewodnym elektrolitem, w którym jest on stosowany
HUE057513T2 (hu) Cellaválasztási és újraválasztási eljárás és végberendezés
PL3200263T3 (pl) Bateria akumulatorowa i sposób jej wytwarzania
EP3706202A4 (en) BATTERY AND METHOD FOR MANUFACTURING A BATTERY
EP3252839A4 (en) Solar cell and solar cell manufacturing method
SG11201706090SA (en) Cell culturing method and kit
EP3340333A4 (en) Curved battery cell having low structural deformation and method for manufacturing same
EP3278388A4 (en) Solid state battery cells and methods for making and using same
EP3309889B8 (en) Secondary battery and manufacturing method thereof
EP3436035A4 (en) COMPOSITIONS AND METHODS FOR USE OF SMALL MOBILE STEM CELLS
EP3687224A4 (en) CELL SELECTION PROCESS AND TERMINAL
EP3515862A4 (en) ELECTROCHEMICAL CELLS AND METHODS OF MAKING SAME
GB201708175D0 (en) Rechargeable electrochemical cells, methods for their manufacture and operation
EP3355375A4 (en) SOLAR CELL AND METHOD OF MANUFACTURING THE SAME
EP3253125A4 (en) Small cell measurement method and terminal
EP3197195A4 (en) Small cell and small cell user authentication method
EP3264826A4 (en) Small cell and small cell user management method