PT3519387T - Derivados de tetrahidropiridina e sua utilização como agentes antibacterianos - Google Patents
Derivados de tetrahidropiridina e sua utilização como agentes antibacterianosInfo
- Publication number
- PT3519387T PT3519387T PT178568101T PT17856810T PT3519387T PT 3519387 T PT3519387 T PT 3519387T PT 178568101 T PT178568101 T PT 178568101T PT 17856810 T PT17856810 T PT 17856810T PT 3519387 T PT3519387 T PT 3519387T
- Authority
- PT
- Portugal
- Prior art keywords
- antibacterial agents
- tetrahydropyridine derivatives
- tetrahydropyridine
- derivatives
- antibacterial
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D211/68—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member
- C07D211/70—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/4418—Non condensed pyridines; Hydrogenated derivatives thereof having a carbocyclic group directly attached to the heterocyclic ring, e.g. cyproheptadine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/02—Drugs for disorders of the urinary system of urine or of the urinary tract, e.g. urine acidifiers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/10—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a carbon chain containing aromatic rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/10—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a carbon chain containing aromatic rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
- C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
- C07D409/10—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing aromatic rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
- C07D413/10—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing aromatic rings
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Epidemiology (AREA)
- Communicable Diseases (AREA)
- Oncology (AREA)
- Dermatology (AREA)
- Urology & Nephrology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Hydrogenated Pyridines (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201662400694P | 2016-09-28 | 2016-09-28 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| PT3519387T true PT3519387T (pt) | 2021-09-28 |
Family
ID=61687790
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PT178568101T PT3519387T (pt) | 2016-09-28 | 2017-09-28 | Derivados de tetrahidropiridina e sua utilização como agentes antibacterianos |
Country Status (15)
| Country | Link |
|---|---|
| US (1) | US10160724B2 (pt) |
| EP (1) | EP3519387B1 (pt) |
| JP (1) | JP6812542B2 (pt) |
| KR (1) | KR102264248B1 (pt) |
| CN (1) | CN110088087B (pt) |
| AU (1) | AU2017337946B2 (pt) |
| BR (1) | BR112019006129A2 (pt) |
| CA (1) | CA3037118C (pt) |
| ES (1) | ES2891025T3 (pt) |
| MX (1) | MX2019003585A (pt) |
| PL (1) | PL3519387T3 (pt) |
| PT (1) | PT3519387T (pt) |
| RU (1) | RU2722594C1 (pt) |
| WO (1) | WO2018062924A1 (pt) |
| ZA (1) | ZA201901945B (pt) |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2019226213A2 (en) | 2018-03-08 | 2019-11-28 | Incyte Corporation | AMINOPYRAZINE DIOL COMPOUNDS AS PI3K-y INHIBITORS |
| WO2020010003A1 (en) | 2018-07-02 | 2020-01-09 | Incyte Corporation | AMINOPYRAZINE DERIVATIVES AS PI3K-γ INHIBITORS |
Family Cites Families (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB0311201D0 (en) * | 2003-05-15 | 2003-06-18 | Merck Sharp & Dohme | Therapeutic agents |
| US7879911B2 (en) * | 2007-02-01 | 2011-02-01 | Johnson Alan T | Hydroxamic acid derivatives of phenoxy-acetic acids and analogs useful as therapeutic agents for treating anthrax poisoning |
| CA2774250C (en) * | 2009-10-13 | 2013-12-17 | Pfizer Inc. | C-linked hydroxamic acid derivatives useful as antibacterial agents |
| CA2830866A1 (en) * | 2011-04-08 | 2012-10-11 | Pfizer Inc. | Imidazole, pyrazole, and triazole derivatives useful as antibacterial agents |
| US8748466B2 (en) * | 2011-04-08 | 2014-06-10 | Pfizer Inc. | Isoxazole derivatives useful as antibacterial agents |
| WO2013170165A1 (en) * | 2012-05-10 | 2013-11-14 | Achaogen, Inc. | Antibacterial agents |
| JP6514716B2 (ja) * | 2014-04-22 | 2019-05-15 | ノバルティス アーゲー | ＬｐｘＣ阻害剤としてのイソオキサゾリンヒドロキサム酸誘導体 |
| EP3143007B1 (en) * | 2014-05-16 | 2018-07-11 | Idorsia Pharmaceuticals Ltd | Antibacterial quinazoline-4(3h)-one derivatives |
| CA3007653A1 (en) * | 2015-12-08 | 2017-06-15 | Glaxosmithkline Intellectual Property Development Limited | Substituted benzazinones as antibacterial compounds |
-
2017
- 2017-09-28 JP JP2019516938A patent/JP6812542B2/ja active Active
- 2017-09-28 US US15/718,474 patent/US10160724B2/en active Active
- 2017-09-28 PT PT178568101T patent/PT3519387T/pt unknown
- 2017-09-28 CN CN201780059711.8A patent/CN110088087B/zh active Active
- 2017-09-28 BR BR112019006129A patent/BR112019006129A2/pt active Search and Examination
- 2017-09-28 AU AU2017337946A patent/AU2017337946B2/en active Active
- 2017-09-28 ES ES17856810T patent/ES2891025T3/es active Active
- 2017-09-28 EP EP17856810.1A patent/EP3519387B1/en active Active
- 2017-09-28 PL PL17856810T patent/PL3519387T3/pl unknown
- 2017-09-28 KR KR1020197012063A patent/KR102264248B1/ko active IP Right Grant
- 2017-09-28 CA CA3037118A patent/CA3037118C/en active Active
- 2017-09-28 RU RU2019112881A patent/RU2722594C1/ru active
- 2017-09-28 WO PCT/KR2017/010896 patent/WO2018062924A1/en unknown
- 2017-09-28 MX MX2019003585A patent/MX2019003585A/es unknown
-
2019
- 2019-03-28 ZA ZA2019/01945A patent/ZA201901945B/en unknown
Also Published As
| Publication number | Publication date |
|---|---|
| JP2019534252A (ja) | 2019-11-28 |
| CN110088087B (zh) | 2022-08-09 |
| BR112019006129A2 (pt) | 2019-06-18 |
| CA3037118C (en) | 2021-12-14 |
| WO2018062924A1 (en) | 2018-04-05 |
| US10160724B2 (en) | 2018-12-25 |
| ES2891025T3 (es) | 2022-01-25 |
| US20180086709A1 (en) | 2018-03-29 |
| ZA201901945B (en) | 2022-07-27 |
| NZ751511A (en) | 2020-11-27 |
| RU2722594C1 (ru) | 2020-06-02 |
| EP3519387A1 (en) | 2019-08-07 |
| CA3037118A1 (en) | 2018-04-05 |
| AU2017337946B2 (en) | 2020-05-07 |
| EP3519387A4 (en) | 2020-05-13 |
| CN110088087A (zh) | 2019-08-02 |
| AU2017337946A1 (en) | 2019-04-04 |
| JP6812542B2 (ja) | 2021-01-13 |
| KR20190047127A (ko) | 2019-05-07 |
| MX2019003585A (es) | 2019-06-10 |
| PL3519387T3 (pl) | 2022-02-07 |
| EP3519387B1 (en) | 2021-08-11 |
| KR102264248B1 (ko) | 2021-06-14 |
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