PT3478705T - Uma estirpe de vírus atenuado da peste suína africana racionalmente desenvolvida protege contra o desafio com o isolado do vírus parental georgia 2007 - Google Patents

Uma estirpe de vírus atenuado da peste suína africana racionalmente desenvolvida protege contra o desafio com o isolado do vírus parental georgia 2007

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Publication number
PT3478705T
PT3478705T PT178210084T PT17821008T PT3478705T PT 3478705 T PT3478705 T PT 3478705T PT 178210084 T PT178210084 T PT 178210084T PT 17821008 T PT17821008 T PT 17821008T PT 3478705 T PT3478705 T PT 3478705T
Authority
PT
Portugal
Prior art keywords
isolate
georgia
protects against
swine fever
african swine
Prior art date
Application number
PT178210084T
Other languages
English (en)
Original Assignee
Us Agriculture
Univ Connecticut
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Us Agriculture, Univ Connecticut filed Critical Us Agriculture
Publication of PT3478705T publication Critical patent/PT3478705T/pt

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    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/005Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/12Viral antigens
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N7/00Viruses; Bacteriophages; Compositions thereof; Preparation or purification thereof
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/70Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving virus or bacteriophage
    • C12Q1/701Specific hybridization probes
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/569Immunoassay; Biospecific binding assay; Materials therefor for microorganisms, e.g. protozoa, bacteria, viruses
    • G01N33/56983Viruses
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6893Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids related to diseases not provided for elsewhere
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2710/00MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
    • C12N2710/00011Details
    • C12N2710/12011Asfarviridae
    • C12N2710/12021Viruses as such, e.g. new isolates, mutants or their genomic sequences
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    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2710/00MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
    • C12N2710/00011Details
    • C12N2710/12011Asfarviridae
    • C12N2710/12034Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2710/00MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
    • C12N2710/00011Details
    • C12N2710/12011Asfarviridae
    • C12N2710/12061Methods of inactivation or attenuation
    • C12N2710/12062Methods of inactivation or attenuation by genetic engineering
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2710/00MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
    • C12N2710/00011Details
    • C12N2710/12011Asfarviridae
    • C12N2710/12071Demonstrated in vivo effect
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/005Assays involving biological materials from specific organisms or of a specific nature from viruses
    • G01N2333/01DNA viruses
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/005Assays involving biological materials from specific organisms or of a specific nature from viruses
    • G01N2333/08RNA viruses
    • G01N2333/18Togaviridae; Flaviviridae
    • G01N2333/183Flaviviridae, e.g. pestivirus, mucosal disease virus, bovine viral diarrhoea virus, classical swine fever virus (hog cholera virus) or border disease virus

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  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Virology (AREA)
  • Microbiology (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Biochemistry (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Biotechnology (AREA)
  • Genetics & Genomics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Urology & Nephrology (AREA)
  • Hematology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Food Science & Technology (AREA)
  • Cell Biology (AREA)
  • Epidemiology (AREA)
  • Mycology (AREA)
  • Biophysics (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
PT178210084T 2016-07-01 2017-06-26 Uma estirpe de vírus atenuado da peste suína africana racionalmente desenvolvida protege contra o desafio com o isolado do vírus parental georgia 2007 PT3478705T (pt)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US15/200,407 US9808520B1 (en) 2016-07-01 2016-07-01 Rationally developed african swine fever attenuated virus strain protects against challenge with parental virus georgia 2007 isolate

Publications (1)

Publication Number Publication Date
PT3478705T true PT3478705T (pt) 2024-02-01

Family

ID=60189680

Family Applications (1)

Application Number Title Priority Date Filing Date
PT178210084T PT3478705T (pt) 2016-07-01 2017-06-26 Uma estirpe de vírus atenuado da peste suína africana racionalmente desenvolvida protege contra o desafio com o isolado do vírus parental georgia 2007

Country Status (28)

Country Link
US (1) US9808520B1 (pt)
EP (1) EP3478705B1 (pt)
JP (1) JP7121950B2 (pt)
KR (1) KR102443074B1 (pt)
CN (1) CN109952310B (pt)
AU (1) AU2017288932B2 (pt)
BR (1) BR112018076633A2 (pt)
CA (1) CA3029552A1 (pt)
CL (1) CL2018003769A1 (pt)
DK (1) DK3478705T5 (pt)
EA (1) EA201990085A1 (pt)
ES (1) ES2971606T3 (pt)
FI (1) FI3478705T3 (pt)
GE (1) GEP20207186B (pt)
HR (1) HRP20240254T1 (pt)
HU (1) HUE065240T2 (pt)
LT (1) LT3478705T (pt)
MX (1) MX2019000048A (pt)
MY (1) MY197376A (pt)
PH (1) PH12018502684A1 (pt)
PL (1) PL3478705T3 (pt)
PT (1) PT3478705T (pt)
RS (1) RS65124B1 (pt)
SG (1) SG11201811370XA (pt)
SI (1) SI3478705T1 (pt)
UA (1) UA125584C2 (pt)
WO (1) WO2018005358A1 (pt)
ZA (1) ZA201900259B (pt)

Families Citing this family (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2017128039A1 (zh) 2016-01-26 2017-08-03 浙江大学 基因组合及其用途
EP3787679A4 (en) * 2019-07-11 2022-03-30 Aptimmune Biologics, Inc. METHODS OF CULTIVATING AFRICAN SWINE FEVER VIRUS IN PORCINE LUNG ALVEOLAR MACROPHAGE CELLS
CN110302371B (zh) * 2019-08-21 2023-05-26 军事科学院军事医学研究院军事兽医研究所 灭活asfv作为复合疫苗的免疫攻毒保护成分的用途
US11007263B2 (en) 2019-09-24 2021-05-18 The United States Of America, As Represented By The Secretary Of Agriculture Development of a novel live attenuated African Swine Fever vaccine based in the deletion of gene I177L
JP7382628B2 (ja) * 2019-10-11 2023-11-17 国立研究開発法人農業・食品産業技術総合研究機構 アフリカ豚コレラウイルスの製造方法及び検出方法
CN110760617B (zh) * 2019-11-26 2021-12-21 华中农业大学 检测非洲猪瘟病毒野毒的实时荧光pcr引物探针组合及试剂盒
KR20210087810A (ko) 2020-01-03 2021-07-13 주식회사 중앙백신연구소 신규한 아프리카돼지열병의 예방 및 치료를 위한 바이러스 백신조성물
CN111925994B (zh) * 2020-07-03 2023-05-26 中国农业科学院兰州兽医研究所 一种dp71l基因缺失的重组非洲猪瘟病毒及其制备方法和应用
CN111748563A (zh) * 2020-07-10 2020-10-09 中国农业科学院兰州兽医研究所 非洲猪瘟基因缺失弱毒株的构建及其作为疫苗的应用
CN112063592A (zh) * 2020-07-10 2020-12-11 中国农业科学院兰州兽医研究所 非洲猪瘟多基因联合缺失减毒株的构建及作为疫苗的应用
CN111996175B (zh) * 2020-09-04 2023-11-21 军事科学院军事医学研究院军事兽医研究所 缺失e66l、i267l基因的非洲猪瘟减毒及活疫苗
JP7477914B2 (ja) * 2020-11-20 2024-05-02 国立研究開発法人農業・食品産業技術総合研究機構 不死化豚胎子小腸マクロファージ
EP4267965A1 (en) 2020-12-24 2023-11-01 Intervet International B.V. African swine fever diva immunoassay
CN112852761B (zh) * 2021-03-08 2022-08-23 中国农业科学院兰州兽医研究所 基因缺失减毒非洲猪瘟病毒株的构建及作为疫苗的应用
CN114392345B (zh) * 2021-03-11 2023-08-25 中国农业科学院哈尔滨兽医研究所(中国动物卫生与流行病学中心哈尔滨分中心) E199l蛋白在促进细胞凋亡中的用途及方法
CN113061588B (zh) * 2021-05-20 2023-08-01 军事科学院军事医学研究院军事兽医研究所 缺失i226r基因的非洲猪瘟病毒减毒株及其活疫苗
US11801296B2 (en) 2021-06-30 2023-10-31 The United States Of America, As Represented By The Secretary Of Agriculture Development of a novel live attenuated African swine fever vaccine based in the deletion of gene A137R
CN114107228B (zh) * 2021-11-11 2023-06-13 中国农业科学院兰州兽医研究所 缺失十二个基因的减毒非洲猪瘟病毒株的构建及其作为疫苗的应用
CN113831394B (zh) * 2021-11-29 2022-04-12 中国人民解放军军事科学院军事医学研究院 一种非洲猪瘟病毒asfv基因的重组病毒组合及由其制备的疫苗
WO2024137601A2 (en) * 2022-12-21 2024-06-27 Colorado State University Research Foundation Systems, methods, and compositions for preparing vaccines comprising inactivated/attenuated pathogens
WO2024189198A1 (en) 2023-03-16 2024-09-19 Intervet International B.V. A vaccine for protecting a pregnant swine against african swine fever

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB8610106D0 (en) * 1986-04-25 1986-05-29 Central Blood Lab Authority Human igm-producing heterohybridoma
US8846055B2 (en) * 2006-05-30 2014-09-30 The United States Of America, As Represented By The Secretary Of Agriculture Virulence determinant within the E2 structural glycoprotein of classical swine fever virus
US9352032B2 (en) * 2014-03-07 2016-05-31 The United States Of America As Represented By The Secretary Of Agriculture Live attenuated antigenically marked classical swine fever vaccine
GB201410971D0 (en) * 2014-06-19 2014-08-06 Pirbright Inst The Vaccine
US9463234B2 (en) * 2014-09-24 2016-10-11 The United States Of America, As Represented By The Secretary Of Agriculture Attenuated african swine fever virus strain induces protection against challenge with homologous virulent parental virus georgia 2007 isolate
US9528094B2 (en) * 2014-11-10 2016-12-27 The United States Of America, As Represented By The Secretary Of Agriculture Attenuated African swine fever virus vaccine based in the deletion of MGF genes

Also Published As

Publication number Publication date
HUE065240T2 (hu) 2024-05-28
DK3478705T5 (da) 2024-10-14
AU2017288932B2 (en) 2022-06-09
CN109952310B (zh) 2023-05-23
MX2019000048A (es) 2019-07-04
ZA201900259B (en) 2019-09-25
GEAP201714984A (pt) 2020-08-10
SI3478705T1 (sl) 2024-04-30
PL3478705T3 (pl) 2024-04-15
JP7121950B2 (ja) 2022-08-19
CL2018003769A1 (es) 2019-03-22
US9808520B1 (en) 2017-11-07
FI3478705T3 (fi) 2024-02-21
UA125584C2 (uk) 2022-04-27
KR20190018020A (ko) 2019-02-20
CN109952310A (zh) 2019-06-28
EP3478705B1 (en) 2023-11-29
EA201990085A1 (ru) 2019-05-31
BR112018076633A2 (pt) 2019-04-24
GEP20207186B (en) 2020-11-25
KR102443074B1 (ko) 2022-09-14
ES2971606T3 (es) 2024-06-06
LT3478705T (lt) 2024-02-26
RS65124B1 (sr) 2024-02-29
HRP20240254T1 (hr) 2024-05-10
JP2019520827A (ja) 2019-07-25
SG11201811370XA (en) 2019-01-30
AU2017288932A1 (en) 2019-02-14
EP3478705A4 (en) 2020-04-29
DK3478705T3 (da) 2024-02-26
WO2018005358A1 (en) 2018-01-04
EP3478705A1 (en) 2019-05-08
CA3029552A1 (en) 2018-01-04
MY197376A (en) 2023-06-14
PH12018502684A1 (en) 2019-04-15

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