PT3381917T - Compostos imidazopiridina e suas utilizações - Google Patents
Compostos imidazopiridina e suas utilizaçõesInfo
- Publication number
- PT3381917T PT3381917T PT18158586T PT18158586T PT3381917T PT 3381917 T PT3381917 T PT 3381917T PT 18158586 T PT18158586 T PT 18158586T PT 18158586 T PT18158586 T PT 18158586T PT 3381917 T PT3381917 T PT 3381917T
- Authority
- PT
- Portugal
- Prior art keywords
- imidazopyridine compounds
- imidazopyridine
- compounds
- Prior art date
Links
- 125000004857 imidazopyridinyl group Chemical class N1C(=NC2=C1C=CC=N2)* 0.000 title 1
Classifications
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
- A61K31/4025—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil not condensed and containing further heterocyclic rings, e.g. cromakalim
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/4353—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems
- A61K31/437—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems the heterocyclic ring system containing a five-membered ring having nitrogen as a ring hetero atom, e.g. indolizine, beta-carboline
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/445—Non condensed piperidines, e.g. piperocaine
- A61K31/4523—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems
- A61K31/4545—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems containing a six-membered ring with nitrogen as a ring hetero atom, e.g. pipamperone, anabasine
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/535—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines
- A61K31/5375—1,4-Oxazines, e.g. morpholine
- A61K31/5377—1,4-Oxazines, e.g. morpholine not condensed and containing further heterocyclic rings, e.g. timolol
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
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- A—HUMAN NECESSITIES
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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- A61P11/06—Antiasthmatics
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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- A—HUMAN NECESSITIES
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- A61P13/00—Drugs for disorders of the urinary system
- A61P13/02—Drugs for disorders of the urinary system of urine or of the urinary tract, e.g. urine acidifiers
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- A61P13/10—Drugs for disorders of the urinary system of the bladder
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- A—HUMAN NECESSITIES
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- A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
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- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
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- A—HUMAN NECESSITIES
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
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- A—HUMAN NECESSITIES
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
- A61P25/16—Anti-Parkinson drugs
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
- A61P25/32—Alcohol-abuse
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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- A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
- A61P25/34—Tobacco-abuse
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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- A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
- A61P25/36—Opioid-abuse
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Organic Chemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Epidemiology (AREA)
- Neurology (AREA)
- Biomedical Technology (AREA)
- Neurosurgery (AREA)
- Addiction (AREA)
- Psychiatry (AREA)
- Pulmonology (AREA)
- Immunology (AREA)
- Pain & Pain Management (AREA)
- Urology & Nephrology (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Rheumatology (AREA)
- Psychology (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Physical Education & Sports Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201361759123P | 2013-01-31 | 2013-01-31 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| PT3381917T true PT3381917T (pt) | 2021-10-27 |
Family
ID=51261357
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PT18158586T PT3381917T (pt) | 2013-01-31 | 2014-01-31 | Compostos imidazopiridina e suas utilizações |
| PT147457220T PT2951177T (pt) | 2013-01-31 | 2014-01-31 | Compostos imidazopiridina e suas utilizações |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PT147457220T PT2951177T (pt) | 2013-01-31 | 2014-01-31 | Compostos imidazopiridina e suas utilizações |
Country Status (17)
| Country | Link |
|---|---|
| US (9) | US9598409B2 (enExample) |
| EP (3) | EP3998267A1 (enExample) |
| JP (1) | JP6373280B2 (enExample) |
| KR (1) | KR102120513B1 (enExample) |
| CN (2) | CN105246888B (enExample) |
| AU (1) | AU2014211962B2 (enExample) |
| BR (1) | BR112015018317B1 (enExample) |
| CA (1) | CA2898665C (enExample) |
| DK (2) | DK3381917T3 (enExample) |
| ES (2) | ES2895225T3 (enExample) |
| MX (1) | MX372934B (enExample) |
| NO (1) | NO2910833T3 (enExample) |
| PL (2) | PL2951177T3 (enExample) |
| PT (2) | PT3381917T (enExample) |
| RU (1) | RU2656593C2 (enExample) |
| TR (1) | TR201807602T4 (enExample) |
| WO (1) | WO2014117274A1 (enExample) |
Families Citing this family (32)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| PT3381917T (pt) * | 2013-01-31 | 2021-10-27 | Bellus Health Cough Inc | Compostos imidazopiridina e suas utilizações |
| HUE055290T2 (hu) | 2014-12-09 | 2021-11-29 | Bayer Ag | 1,3-Tiazol-2-il-csoporttal szubsztituált benzamid-származékok |
| US9907795B2 (en) * | 2016-01-08 | 2018-03-06 | Nerre Therapeutics Limited | Method of treatment of chronic cough administering orvepitant in combination with other therapeutic agents |
| KR20190053963A (ko) | 2016-09-30 | 2019-05-20 | 아사나 바이오사이언시스 엘엘씨 | P2x3 및/또는 p2x2/3 화합물 및 방법 |
| EP3339307A1 (en) * | 2016-12-20 | 2018-06-27 | Laboratorios del Dr. Esteve, S.A. | Nitrogen containing bicyclic derivatives for treating pain and pain related conditions |
| US10111883B1 (en) | 2017-09-18 | 2018-10-30 | Bellus Health Cough Inc. | Selective P2X3 modulators |
| KR102613204B1 (ko) | 2018-10-05 | 2023-12-12 | 시오노기 앤드 컴파니, 리미티드 | 만성 해수 치료용 의약 |
| CA3115939A1 (en) * | 2018-10-10 | 2020-04-16 | Bellus Health Cough Inc. | Treatment of pruritus with p2x3 antagonists |
| LT3880678T (lt) * | 2018-11-13 | 2025-06-25 | Glaxosmithkline Intellectual Property (No.3) Limited | P2x3 moduliatoriaus metilo (s)-2-((2-(2,6-difluor-4-(metilkarbamoil)fenil) -7-metilimidazo[1,2-a]piridin-3-il)metil)morfolin-4-karboksilato kristalinės formos |
| US20240034729A9 (en) * | 2018-12-29 | 2024-02-01 | Wuhan Ll Science And Technology Development Co., Ltd. | Heterocyclic compound, intermediate, preparation method therefor and application thereof |
| JP7578602B2 (ja) * | 2019-02-25 | 2024-11-06 | グラクソスミスクライン、インテレクチュアル、プロパティー、（ナンバー３）、リミテッド | Ｐ２ｘ３修飾薬での治療 |
| CN112409331B (zh) * | 2019-08-21 | 2024-02-20 | 上海翰森生物医药科技有限公司 | 杂环类衍生物抑制剂、其制备方法和应用 |
| WO2021161109A1 (en) * | 2020-02-14 | 2021-08-19 | Bellus Health Cough Inc. | Preparation of a p2x3 antagonist |
| US20230312557A1 (en) * | 2020-02-14 | 2023-10-05 | Bellus Health Cough Inc. | P2x3 modulators |
| CN113549068B (zh) * | 2020-04-24 | 2022-12-02 | 上海拓界生物医药科技有限公司 | 一类新型咪唑并吡啶化合物、其制备方法及其在医药上的应用 |
| WO2021244634A1 (zh) * | 2020-06-05 | 2021-12-09 | 武汉人福创新药物研发中心有限公司 | 咪唑并吡啶类化合物及其用途 |
| CN114085220B (zh) * | 2020-06-22 | 2023-06-16 | 上海海雁医药科技有限公司 | 取代的吗啉-4-羧酸酯衍生物、其组合物及医药上的用途 |
| CA3184482A1 (en) * | 2020-06-29 | 2022-01-06 | Liang Wang | Crystalline form of heterocyclic compound, preparation method therefor and application thereof |
| CN113912601B (zh) * | 2020-07-10 | 2023-06-06 | 上海拓界生物医药科技有限公司 | 一类新的咪唑并[1,2-a]吡啶类衍生物、其制备方法及医药用途 |
| CN115835867B (zh) * | 2020-08-13 | 2025-09-09 | 江苏恒瑞医药股份有限公司 | 苯并咪唑类衍生物、其制备方法及医药用途 |
| CN112485351A (zh) * | 2020-11-18 | 2021-03-12 | 天津华津制药有限公司 | 一种右佐匹克隆光学异构体的检测方法 |
| WO2022117062A1 (zh) * | 2020-12-04 | 2022-06-09 | 上海拓界生物医药科技有限公司 | 含有稠合三环的化合物及其医药用途 |
| CN114805340A (zh) * | 2021-01-22 | 2022-07-29 | 武汉人福创新药物研发中心有限公司 | 咪唑并吡啶类化合物的制备方法及其中间体 |
| WO2022156784A1 (zh) * | 2021-01-22 | 2022-07-28 | 武汉人福创新药物研发中心有限公司 | 杂环类化合物的制备方法及其中间体 |
| WO2022258059A1 (zh) * | 2021-06-10 | 2022-12-15 | 武汉朗来科技发展有限公司 | 一种药物组合物、制剂及其制备方法和应用 |
| CN117460720A (zh) * | 2021-06-24 | 2024-01-26 | 武汉朗来科技发展有限公司 | 一种杂环烷基类化合物的制备方法、其中间体及其应用 |
| EP4387959A4 (en) * | 2021-08-17 | 2025-07-02 | Glaxosmithkline Intellectual Property No 3 Ltd | PREPARATION OF A P2X3 ANTAGONIST |
| WO2023020156A1 (zh) * | 2021-08-20 | 2023-02-23 | 苏州璞正医药有限公司 | 一种咪唑并吡啶衍生物的p2x3受体选择性调节剂及其药物用途 |
| CN120917022A (zh) | 2023-03-23 | 2025-11-07 | 葛兰素史密斯克莱知识产权(第3号)有限公司 | 氘代p2x3调节剂 |
| WO2025125445A1 (en) | 2023-12-12 | 2025-06-19 | Glaxosmithkline Intellectual Property (No.3) Limited | Process of manufacture of p2x3 antagonists including camlipixant |
| WO2025191081A1 (en) | 2024-03-15 | 2025-09-18 | Glaxosmithkline Intellectual Property (No.3) Limited | Crystalline form of camlipixant |
| WO2025210540A1 (en) | 2024-04-02 | 2025-10-09 | Assia Chemical Industries Ltd. | Solid state forms of camlipixant and process for preparation thereof |
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| GB9119920D0 (en) | 1991-09-18 | 1991-10-30 | Glaxo Group Ltd | Chemical compounds |
| GB9624482D0 (en) | 1995-12-18 | 1997-01-15 | Zeneca Phaema S A | Chemical compounds |
| BR9707495A (pt) | 1996-02-13 | 1999-07-27 | Zeneca Ltd | Derivado de quinazolina processo para a preparação do mesmo composição farmacêutica e processo para a produç o de um efeito antiangiogênico e/ou de redução de permeabilidade vascular em um animal de sangue quente |
| JP4464466B2 (ja) | 1996-03-05 | 2010-05-19 | アストラゼネカ・ユーケイ・リミテッド | ４―アニリノキナゾリン誘導体 |
| GB9718972D0 (en) | 1996-09-25 | 1997-11-12 | Zeneca Ltd | Chemical compounds |
| GB9714249D0 (en) | 1997-07-08 | 1997-09-10 | Angiogene Pharm Ltd | Vascular damaging agents |
| GB9900334D0 (en) | 1999-01-07 | 1999-02-24 | Angiogene Pharm Ltd | Tricylic vascular damaging agents |
| GB9900752D0 (en) | 1999-01-15 | 1999-03-03 | Angiogene Pharm Ltd | Benzimidazole vascular damaging agents |
| PL199802B1 (pl) | 1999-02-10 | 2008-10-31 | Astrazeneca Ab | Pochodne chinazoliny, sposoby ich wytwarzania, ich kompozycje farmaceutyczne i ich zastosowania |
| IL152682A0 (en) | 2000-05-31 | 2003-06-24 | Astrazeneca Ab | Indole derivatives with vascular damaging activity |
| UA73993C2 (uk) | 2000-06-06 | 2005-10-17 | Астразенека Аб | Хіназолінові похідні для лікування пухлин та фармацевтична композиція |
| JP2004502766A (ja) | 2000-07-07 | 2004-01-29 | アンギオジェン・ファーマシューティカルズ・リミテッド | 血管損傷剤としてのコルヒノール誘導体 |
| CA2410562A1 (en) | 2000-07-07 | 2002-01-31 | Angiogene Pharmaceuticals Limited | Colchinol derivatives as angiogenesis inhibitors |
| SE0102808D0 (sv) * | 2001-08-22 | 2001-08-22 | Astrazeneca Ab | New compounds |
| RU2374234C2 (ru) | 2004-09-24 | 2009-11-27 | Астразенека Аб | Бензимидазольные производные, содержащие их композиции, их получение и применение |
| DE102006028862A1 (de) * | 2006-06-23 | 2007-12-27 | Merck Patent Gmbh | 3-Amino-imidazo[1,2-a]pyridinderivate |
| KR101103143B1 (ko) * | 2006-06-29 | 2012-01-04 | 에프. 호프만-라 로슈 아게 | 테트라졸-치환된 아릴아마이드 |
| US20090099195A1 (en) | 2007-05-08 | 2009-04-16 | Astrazeneca Ab | Therapeutic Compounds 570 |
| US9238647B2 (en) * | 2009-03-23 | 2016-01-19 | Merck Sharp & Dohme Corp. | P2X3 receptor antagonists for treatment of pain |
| JP5657018B2 (ja) | 2009-11-18 | 2015-01-21 | アストラゼネカ・アクチエボラーグＡｓｔｒａｚｅｎｅｃａ Ａｋｔｉｅｂｏｌａｇ | ベンゾイミダゾール化合物及びその使用 |
| PT3381917T (pt) | 2013-01-31 | 2021-10-27 | Bellus Health Cough Inc | Compostos imidazopiridina e suas utilizações |
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2014
- 2014-01-31 PT PT18158586T patent/PT3381917T/pt unknown
- 2014-01-31 PT PT147457220T patent/PT2951177T/pt unknown
- 2014-01-31 DK DK18158586.0T patent/DK3381917T3/da active
- 2014-01-31 EP EP21195015.9A patent/EP3998267A1/en active Pending
- 2014-01-31 PL PL14745722T patent/PL2951177T3/pl unknown
- 2014-01-31 TR TR2018/07602T patent/TR201807602T4/tr unknown
- 2014-01-31 EP EP14745722.0A patent/EP2951177B1/en active Active
- 2014-01-31 ES ES18158586T patent/ES2895225T3/es active Active
- 2014-01-31 KR KR1020157023171A patent/KR102120513B1/ko active Active
- 2014-01-31 US US14/764,404 patent/US9598409B2/en active Active
- 2014-01-31 JP JP2015555508A patent/JP6373280B2/ja active Active
- 2014-01-31 DK DK14745722.0T patent/DK2951177T3/en active
- 2014-01-31 RU RU2015133450A patent/RU2656593C2/ru active
- 2014-01-31 ES ES14745722.0T patent/ES2674087T3/es active Active
- 2014-01-31 EP EP18158586.0A patent/EP3381917B1/en active Active
- 2014-01-31 CN CN201480007024.8A patent/CN105246888B/zh active Active
- 2014-01-31 BR BR112015018317-4A patent/BR112015018317B1/pt active IP Right Grant
- 2014-01-31 MX MX2015009950A patent/MX372934B/es active IP Right Grant
- 2014-01-31 WO PCT/CA2014/050062 patent/WO2014117274A1/en not_active Ceased
- 2014-01-31 AU AU2014211962A patent/AU2014211962B2/en active Active
- 2014-01-31 CA CA2898665A patent/CA2898665C/en active Active
- 2014-01-31 CN CN201710680673.XA patent/CN107485612B/zh active Active
- 2014-01-31 PL PL18158586T patent/PL3381917T3/pl unknown
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2015
- 2015-01-30 NO NO15153188A patent/NO2910833T3/no unknown
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2017
- 2017-02-02 US US15/423,428 patent/US9814725B2/en active Active
- 2017-09-26 US US15/716,410 patent/US9937185B2/en active Active
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2018
- 2018-02-27 US US15/906,230 patent/US20190030040A1/en not_active Abandoned
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2019
- 2019-04-04 US US16/375,773 patent/US20190231789A1/en not_active Abandoned
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2020
- 2020-01-07 US US16/736,599 patent/US20200138826A1/en not_active Abandoned
- 2020-08-27 US US17/005,238 patent/US20200390779A1/en not_active Abandoned
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2021
- 2021-04-08 US US17/225,753 patent/US20210228588A1/en not_active Abandoned
- 2021-11-10 US US17/523,767 patent/US20220062290A1/en not_active Abandoned
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