PT3215158T - Apilimod para utilização no tratamento de cancro renal - Google Patents

Apilimod para utilização no tratamento de cancro renal

Info

Publication number
PT3215158T
PT3215158T PT15795318T PT15795318T PT3215158T PT 3215158 T PT3215158 T PT 3215158T PT 15795318 T PT15795318 T PT 15795318T PT 15795318 T PT15795318 T PT 15795318T PT 3215158 T PT3215158 T PT 3215158T
Authority
PT
Portugal
Prior art keywords
apilimod
treatment
renal cancer
renal
cancer
Prior art date
Application number
PT15795318T
Other languages
English (en)
Portuguese (pt)
Inventor
BEEHARRY Neil
Gayle Sophia
LANDRETTE Sean
Beckett Paul
Conrad Chris
Xu Tian
M Rothberg Jonathan
Lichenstein Henri
Original Assignee
Ai Therapeutics Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ai Therapeutics Inc filed Critical Ai Therapeutics Inc
Publication of PT3215158T publication Critical patent/PT3215158T/pt

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/506—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim not condensed and containing further heterocyclic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/535—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines
    • A61K31/5375—1,4-Oxazines, e.g. morpholine
    • A61K31/5377—1,4-Oxazines, e.g. morpholine not condensed and containing further heterocyclic rings, e.g. timolol
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/12—Drugs for disorders of the urinary system of the kidneys
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/04—Antineoplastic agents specific for metastasis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2300/00—Mixtures or combinations of active ingredients, wherein at least one active ingredient is fully defined in groups A61K31/00 - A61K41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical & Material Sciences (AREA)
  • Epidemiology (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Dermatology (AREA)
  • Urology & Nephrology (AREA)
  • Oncology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Peptides Or Proteins (AREA)
PT15795318T 2014-11-07 2015-11-06 Apilimod para utilização no tratamento de cancro renal PT3215158T (pt)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US201462077127P 2014-11-07 2014-11-07

Publications (1)

Publication Number Publication Date
PT3215158T true PT3215158T (pt) 2019-08-23

Family

ID=54548302

Family Applications (1)

Application Number Title Priority Date Filing Date
PT15795318T PT3215158T (pt) 2014-11-07 2015-11-06 Apilimod para utilização no tratamento de cancro renal

Country Status (16)

Country Link
US (3) US10206910B2 (enExample)
EP (2) EP3215158B1 (enExample)
JP (1) JP6705828B2 (enExample)
KR (1) KR20170098812A (enExample)
CN (1) CN107249638B (enExample)
AU (1) AU2015342869A1 (enExample)
BR (1) BR112017008799A2 (enExample)
CA (1) CA2966359A1 (enExample)
ES (1) ES2741399T3 (enExample)
HU (1) HUE044557T2 (enExample)
IL (1) IL251905B (enExample)
MX (1) MX377593B (enExample)
PL (1) PL3215158T3 (enExample)
PT (1) PT3215158T (enExample)
RU (1) RU2727802C2 (enExample)
WO (1) WO2016073877A1 (enExample)

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ES2741399T3 (es) 2014-11-07 2020-02-10 Ai Therapeutics Inc Apilimod para el uso en el tratamiento de cáncer renal
RU2018130070A (ru) * 2016-01-21 2020-02-21 Лэм Терапьютикс, Инк. Биомаркеры для лечения рака при помощи апилимода
CA3034453A1 (en) * 2016-08-25 2018-03-01 AI Therapeutics, Inc. Compositions comprising pikfyve inhibitors and methods related to inhibition of rank signaling
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US11066410B2 (en) 2017-03-24 2021-07-20 3100 Central Expressway Llc Fused triazolo-pyrimidine compounds having useful pharmaceutical application
JP7517988B2 (ja) 2018-01-26 2024-07-17 ザ リージェンツ オブ ザ ユニバーシティ オブ カリフォルニア 抗ｖｅｇｆ剤を使用した血管新生障害の治療のための方法および組成物
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CA3168512A1 (en) 2019-11-25 2021-06-03 Napoleone Ferrara Long-acting vegf inhibitors for intraocular neovascularization
TWI885039B (zh) 2020-01-13 2025-06-01 美商邊際分析公司 經取代吡唑并嘧啶及其用途
CN114306370A (zh) * 2021-12-31 2022-04-12 北京悦康科创医药科技股份有限公司 反义寡核苷酸在制备治疗肾癌药物中的应用

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ES2734081T3 (es) 2014-11-07 2019-12-04 Ai Therapeutics Inc Apilimod para el uso en el tratamiento de melanoma
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Also Published As

Publication number Publication date
CA2966359A1 (en) 2016-05-12
IL251905A0 (en) 2017-06-29
US20190201385A1 (en) 2019-07-04
CN107249638A (zh) 2017-10-13
EP3215158B1 (en) 2019-05-08
JP2017535601A (ja) 2017-11-30
KR20170098812A (ko) 2017-08-30
EP3581184B1 (en) 2021-02-24
US11166944B2 (en) 2021-11-09
ES2741399T3 (es) 2020-02-10
EP3215158A1 (en) 2017-09-13
US20170333408A1 (en) 2017-11-23
RU2727802C2 (ru) 2020-07-24
JP6705828B2 (ja) 2020-06-03
HUE044557T2 (hu) 2019-11-28
AU2015342869A1 (en) 2017-06-15
RU2017119065A3 (enExample) 2019-06-05
US20200297706A1 (en) 2020-09-24
CN107249638B (zh) 2021-05-14
MX377593B (es) 2025-03-10
WO2016073877A1 (en) 2016-05-12
RU2017119065A (ru) 2018-12-07
PL3215158T3 (pl) 2019-11-29
IL251905B (en) 2021-03-25
MX2017006015A (es) 2017-11-17
EP3581184A1 (en) 2019-12-18
US10206910B2 (en) 2019-02-19
BR112017008799A2 (pt) 2017-12-19

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