PT3157930T - Métodos para a preparação de compostos heterocíclicos de 1,3-benzodioxole - Google Patents

Métodos para a preparação de compostos heterocíclicos de 1,3-benzodioxole

Info

Publication number
PT3157930T
PT3157930T PT15730183T PT15730183T PT3157930T PT 3157930 T PT3157930 T PT 3157930T PT 15730183 T PT15730183 T PT 15730183T PT 15730183 T PT15730183 T PT 15730183T PT 3157930 T PT3157930 T PT 3157930T
Authority
PT
Portugal
Prior art keywords
preparation
methods
heterocyclic compounds
benzodioxole
benzodioxole heterocyclic
Prior art date
Application number
PT15730183T
Other languages
English (en)
Portuguese (pt)
Inventor
Metzler Bjorn
Faldt André
Original Assignee
Leo Pharma As
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Leo Pharma As filed Critical Leo Pharma As
Publication of PT3157930T publication Critical patent/PT3157930T/pt

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/357—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having two or more oxygen atoms in the same ring, e.g. crown ethers, guanadrel
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/4427—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
    • C07D495/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
    • C07D495/10—Spiro-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Catalysts (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
PT15730183T 2014-06-23 2015-06-22 Métodos para a preparação de compostos heterocíclicos de 1,3-benzodioxole PT3157930T (pt)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP14173397 2014-06-23

Publications (1)

Publication Number Publication Date
PT3157930T true PT3157930T (pt) 2018-12-24

Family

ID=50980952

Family Applications (1)

Application Number Title Priority Date Filing Date
PT15730183T PT3157930T (pt) 2014-06-23 2015-06-22 Métodos para a preparação de compostos heterocíclicos de 1,3-benzodioxole

Country Status (18)

Country Link
US (1) US9908894B2 (enExample)
EP (1) EP3157930B1 (enExample)
JP (1) JP6785666B2 (enExample)
KR (1) KR20170016894A (enExample)
CN (1) CN106459081B (enExample)
AU (1) AU2015279428B2 (enExample)
BR (1) BR112016029510A2 (enExample)
CA (1) CA2953284A1 (enExample)
DK (1) DK3157930T3 (enExample)
ES (1) ES2702451T3 (enExample)
IL (1) IL249336A0 (enExample)
MX (1) MX2016016378A (enExample)
PL (1) PL3157930T3 (enExample)
PT (1) PT3157930T (enExample)
RU (1) RU2697251C2 (enExample)
TW (1) TW201613934A (enExample)
WO (1) WO2015197534A2 (enExample)
ZA (1) ZA201608442B (enExample)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DK3390407T3 (da) 2015-12-18 2023-11-06 Union Therapeutics As Fremgangsmåder til fremstilling af heterocykliske 1,3-benzodioxolforbindelser
AU2018286964B2 (en) 2017-06-20 2022-04-14 UNION therapeutics A/S Methods for the preparation of 1,3-benzodioxole heterocyclic compounds
WO2019115776A1 (en) 2017-12-15 2019-06-20 Leo Pharma A/S Substituted azetidine dihydrothienopyridines and their use as phosphodiesterase inhibitors
USD914676S1 (en) 2018-05-11 2021-03-30 Samsung Electronics Co., Ltd. Notebook computer
KR20210117300A (ko) 2019-01-15 2021-09-28 유니온 테라퓨틱스 에이/에스 포스포디에스테라제 억제제를 함유하는 변형 방출 정제 제형
KR20230159485A (ko) 2021-03-22 2023-11-21 유니온 테라퓨틱스 에이/에스 오리스밀라스트를 사용한 화농땀샘염의 치료
GB202205715D0 (en) 2022-04-19 2022-06-01 Union Therapeutics As Treatment of neutrophilic dermatoses
GB202306663D0 (en) 2023-05-05 2023-06-21 Union Therapeutics As Combination therapy
GB202306662D0 (en) 2023-05-05 2023-06-21 Union Therapeutics As Dosage regimen

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
HK1000785A1 (en) * 1995-05-19 2006-06-30 Kyowa Hakko Kogyo Co., Ltd Oxygen-containing heterocyclic compounds
US6514996B2 (en) * 1995-05-19 2003-02-04 Kyowa Hakko Kogyo Co., Ltd. Derivatives of benzofuran or benzodioxole
DE10205274A1 (de) * 2002-02-08 2003-08-21 Boehringer Ingelheim Pharma Neue Arzneimittelkompositionen enthaltend neben Anticholinergika heterocyclische Verbindungen
AU2003252467A1 (en) * 2002-07-03 2004-01-23 Kyowa Hakko Kogyo Co., Ltd. Process for preparation of 1,3-benzodioxole-2-spiro- cycloalkane derivatives
DE602007012105D1 (de) * 2006-07-14 2011-03-03 Chiesi Farma Spa Derivate von 1-phenyl-2-pyridinylalkylenalkohole als phosphodiesteraseinhibitoren
US8148537B2 (en) 2006-12-22 2012-04-03 Leo Pharma A/S Substituted acetophenones useful as PDE4 inhibitors
PL2114951T3 (pl) * 2007-02-28 2014-10-31 Leo Pharma As Nowe inhibitory fosfodiesterazy
ZA200905371B (en) * 2007-02-28 2010-10-27 Leo Pharma As Novel phosphodiesterase Inhibitors
JP6174997B2 (ja) * 2010-06-24 2017-08-02 レオ ファーマ アクティーゼルスカブ ホスホジエステラーゼ阻害剤としてのベンゾジオキソールまたはベンゾジオキセピンヘテロ環化合物
WO2014096018A1 (en) * 2012-12-19 2014-06-26 Leo Pharma A/S Methods for the preparation of substituted acetophenones
DK3390407T3 (da) * 2015-12-18 2023-11-06 Union Therapeutics As Fremgangsmåder til fremstilling af heterocykliske 1,3-benzodioxolforbindelser

Also Published As

Publication number Publication date
CN106459081B (zh) 2019-09-10
AU2015279428B2 (en) 2018-02-15
US20170137438A1 (en) 2017-05-18
WO2015197534A3 (en) 2016-03-17
ES2702451T3 (es) 2019-03-01
IL249336A0 (en) 2017-02-28
EP3157930B1 (en) 2018-10-17
ZA201608442B (en) 2018-05-30
TW201613934A (en) 2016-04-16
RU2017101808A3 (enExample) 2019-01-22
JP6785666B2 (ja) 2020-11-18
CA2953284A1 (en) 2015-12-30
JP2017520547A (ja) 2017-07-27
DK3157930T3 (en) 2019-01-21
WO2015197534A2 (en) 2015-12-30
EP3157930A2 (en) 2017-04-26
MX2016016378A (es) 2017-10-16
RU2697251C2 (ru) 2019-08-13
US9908894B2 (en) 2018-03-06
RU2017101808A (ru) 2018-07-27
BR112016029510A2 (pt) 2017-08-22
PL3157930T3 (pl) 2019-04-30
KR20170016894A (ko) 2017-02-14
CN106459081A (zh) 2017-02-22
AU2015279428A1 (en) 2017-01-05

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