PT3074518T - Epissomas estáveis baseados em vetores lentivirais não integrativos - Google Patents
Epissomas estáveis baseados em vetores lentivirais não integrativosInfo
- Publication number
- PT3074518T PT3074518T PT148305147T PT14830514T PT3074518T PT 3074518 T PT3074518 T PT 3074518T PT 148305147 T PT148305147 T PT 148305147T PT 14830514 T PT14830514 T PT 14830514T PT 3074518 T PT3074518 T PT 3074518T
- Authority
- PT
- Portugal
- Prior art keywords
- lentiviral vectors
- integrative lentiviral
- stable episomes
- stable
- episomes based
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
- C12N15/85—Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
- C12N15/86—Viral vectors
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N7/00—Viruses; Bacteriophages; Compositions thereof; Preparation or purification thereof
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2740/00—Reverse transcribing RNA viruses
- C12N2740/00011—Details
- C12N2740/10011—Retroviridae
- C12N2740/10041—Use of virus, viral particle or viral elements as a vector
- C12N2740/10043—Use of virus, viral particle or viral elements as a vector viral genome or elements thereof as genetic vector
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2740/00—Reverse transcribing RNA viruses
- C12N2740/00011—Details
- C12N2740/10011—Retroviridae
- C12N2740/15011—Lentivirus, not HIV, e.g. FIV, SIV
- C12N2740/15041—Use of virus, viral particle or viral elements as a vector
- C12N2740/15043—Use of virus, viral particle or viral elements as a vector viral genome or elements thereof as genetic vector
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2820/00—Vectors comprising a special origin of replication system
- C12N2820/80—Vectors comprising a special origin of replication system from vertebrates
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2820/00—Vectors comprising a special origin of replication system
- C12N2820/80—Vectors comprising a special origin of replication system from vertebrates
- C12N2820/85—Vectors comprising a special origin of replication system from vertebrates mammalian
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2830/00—Vector systems having a special element relevant for transcription
- C12N2830/46—Vector systems having a special element relevant for transcription elements influencing chromatin structure, e.g. scaffold/matrix attachment region, methylation free island
Landscapes
- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Engineering & Computer Science (AREA)
- Chemical & Material Sciences (AREA)
- Wood Science & Technology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Organic Chemistry (AREA)
- Zoology (AREA)
- Biomedical Technology (AREA)
- Biotechnology (AREA)
- General Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Virology (AREA)
- Microbiology (AREA)
- Biochemistry (AREA)
- Physics & Mathematics (AREA)
- Biophysics (AREA)
- Molecular Biology (AREA)
- Plant Pathology (AREA)
- Immunology (AREA)
- Medicinal Chemistry (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP13382481.3A EP2878674A1 (en) | 2013-11-28 | 2013-11-28 | Stable episomes based on non-integrative lentiviral vectors |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| PT3074518T true PT3074518T (pt) | 2020-11-11 |
Family
ID=49759238
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PT148305147T PT3074518T (pt) | 2013-11-28 | 2014-11-27 | Epissomas estáveis baseados em vetores lentivirais não integrativos |
Country Status (11)
| Country | Link |
|---|---|
| US (1) | US10294492B2 (pt) |
| EP (2) | EP2878674A1 (pt) |
| JP (1) | JP6694386B2 (pt) |
| CN (1) | CN106170552B (pt) |
| AU (1) | AU2014356427B2 (pt) |
| CA (1) | CA2931948C (pt) |
| DK (1) | DK3074518T3 (pt) |
| ES (1) | ES2821782T3 (pt) |
| IL (1) | IL245907A0 (pt) |
| PT (1) | PT3074518T (pt) |
| WO (1) | WO2015078999A1 (pt) |
Families Citing this family (18)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2010045659A1 (en) | 2008-10-17 | 2010-04-22 | American Gene Technologies International Inc. | Safe lentiviral vectors for targeted delivery of multiple therapeutic molecules |
| JP6924487B2 (ja) * | 2015-06-10 | 2021-08-25 | アメリカン ジーン テクノロジーズ インターナショナル インコーポレイテッド | 非組み込みウイルス送達システムおよびその使用の方法 |
| WO2017007994A1 (en) | 2015-07-08 | 2017-01-12 | American Gene Technologies International Inc. | Hiv pre-immunization and immunotherapy |
| CN108883100B (zh) | 2016-01-15 | 2022-11-25 | 美国基因技术国际有限公司 | 用于活化γ-δT细胞的方法和组合物 |
| US10137144B2 (en) | 2016-01-15 | 2018-11-27 | American Gene Technologies International Inc. | Methods and compositions for the activation of gamma-delta T-cells |
| JP7153332B2 (ja) | 2016-02-08 | 2022-10-14 | アメリカン ジーン テクノロジーズ インターナショナル インコーポレイテッド | Ｈｉｖワクチン接種および免疫療法 |
| EP4036231A1 (en) | 2016-03-09 | 2022-08-03 | American Gene Technologies International Inc. | Combination vectors and methods for treating cancer |
| US11976292B2 (en) | 2016-06-08 | 2024-05-07 | American Gene Technologies International Inc. | Non-integrating viral delivery system and methods related thereto |
| AU2017292582C1 (en) | 2016-07-08 | 2021-11-11 | American Gene Technologies International Inc. | HIV pre-immunization and immunotherapy |
| WO2018017882A1 (en) | 2016-07-21 | 2018-01-25 | American Gene Technologies International Inc. | Viral vectors for treating parkinson's disease |
| WO2018187231A2 (en) | 2017-04-03 | 2018-10-11 | American Gene Technologies International Inc. | Compositions and methods for treating phenylketonuria |
| DK3456821T4 (da) | 2017-09-19 | 2024-04-15 | Deutsches Krebsforsch | Ikke-integrerende dna-vektorer til genetisk modifikation af celler |
| WO2020035598A1 (en) * | 2018-08-16 | 2020-02-20 | Fundación Pública Andaluza Progreso Y Salud | Is2 element to improved integration-defective lentiviral vectors |
| US11352646B2 (en) | 2018-11-05 | 2022-06-07 | American Gene Technologies International Inc. | Vector system for expressing regulatory RNA |
| CN114423863A (zh) * | 2019-03-18 | 2022-04-29 | 德国癌症研究中心 | 用于细胞遗传修饰的表达构建体 |
| CN110317888A (zh) * | 2019-04-03 | 2019-10-11 | 云南农业大学 | 一种猫血巴尔通氏体SYBR Green I荧光PCR检测方法及引物 |
| CN111471717B (zh) * | 2020-04-17 | 2021-05-04 | 复百澳（苏州）生物科技有限公司 | 一种用于2019新冠病毒核酸检测的假病毒的制备方法 |
| CA3235865A1 (en) | 2021-10-25 | 2023-05-04 | Genvivo, Inc. | Compositions and methods for therapeutic or vaccine delivery |
Family Cites Families (19)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5866755A (en) | 1993-06-14 | 1999-02-02 | Basf Aktiengellschaft | Animals transgenic for a tetracycline-regulated transcriptional inhibitor |
| DE69738521T2 (de) | 1996-04-05 | 2009-05-07 | Novartis Vaccines and Diagnostics, Inc., Emeryville | Alphaviren-vektors mit einer reduzierten inhibierung der synthese von zellmakromolekülen |
| US6534314B1 (en) | 1996-06-14 | 2003-03-18 | Massachusetts Institute Of Technology | Methods and compositions for transforming cells |
| WO2000006205A1 (en) | 1998-07-29 | 2000-02-10 | Invitrogen Corporation | Regulated expression of recombinant proteins using rna viruses |
| CA2407050A1 (en) | 2000-04-25 | 2001-11-01 | Chiron Corporation | Alphavirus-based vectors for persistent infection |
| DE10148294C1 (de) | 2001-09-29 | 2003-01-16 | Unicor Rohrsysteme Gmbh | Formbackenhälfte für einen Corrugator zum Herstellen von Querrippenrohren |
| JP3755028B2 (ja) * | 2002-02-25 | 2006-03-15 | 国立大学法人広島大学 | 哺乳動物細胞内で目的遺伝子を高度に増幅させるための方法 |
| AU2003234734A1 (en) | 2002-04-29 | 2003-11-17 | Saint Louis University | Peptide antagonists of tgf-beta family members and therapeutic uses thereof |
| WO2005005644A1 (en) * | 2003-07-11 | 2005-01-20 | Cytos Biotechnology Ag | Gene expression system |
| ES2304069B1 (es) | 2003-08-22 | 2009-08-12 | Proyecto De Biomedicina Cima, S.L. | Peptidos con capacidad de unirse al factor transformante de crecimiento beta 1 (tgf-b1). |
| ES2292271B1 (es) | 2004-05-20 | 2009-02-16 | Proyecto De Biomedicina Cima, S.L. | Un vector hibrido adenovirus-alfavirus para la administracion eficaz y expresion de genes terapeuticos en celulas tumorales. |
| BRPI0719572A2 (pt) | 2006-11-28 | 2013-12-10 | Proyecto Biomedicina Cima Sl | Vetor viral, uso de um vetor viral, linhagem de células estáveis, método de geração in vitro de uma linhagem de células estáveis, uso de uma linhagem de células estáveis e método de produção in vitro de um produto heterólogo |
| WO2009019612A2 (en) * | 2007-08-03 | 2009-02-12 | Institut Pasteur | Lentiviral gene transfer vectors and their medicinal applications |
| HUE033517T2 (en) * | 2007-08-03 | 2017-12-28 | Pasteur Institut | Defective non-integrating lentivirus transfer vectors for vaccines |
| ES2330826B1 (es) * | 2008-06-04 | 2010-07-26 | Proyecto De Biomedicina Cima, S.L. | Sistema para empaquetamiento de adenovirus de alta capacidad. |
| US20120135034A1 (en) * | 2009-03-13 | 2012-05-31 | Boro Dropulic | Non-Integrating Retroviral Vector Vaccines |
| US20120128631A1 (en) * | 2009-05-19 | 2012-05-24 | San Diego State University (SDSU) Foundation, dba San Diego State University (SDSU) Research | Compositions and methods for kinase-mediated cytoprotection and enhanced cellular engraftment and persistence |
| EP2385107B1 (en) * | 2010-05-03 | 2016-08-24 | Institut Pasteur | Lentiviral vector based immunological compounds against malaria |
| GB201206455D0 (en) * | 2012-04-12 | 2012-05-30 | Royal Holloway & Bedford New College | Gene expression |
-
2013
- 2013-11-28 EP EP13382481.3A patent/EP2878674A1/en not_active Withdrawn
-
2014
- 2014-11-27 DK DK14830514.7T patent/DK3074518T3/da active
- 2014-11-27 PT PT148305147T patent/PT3074518T/pt unknown
- 2014-11-27 AU AU2014356427A patent/AU2014356427B2/en active Active
- 2014-11-27 WO PCT/EP2014/075869 patent/WO2015078999A1/en active Application Filing
- 2014-11-27 JP JP2016534961A patent/JP6694386B2/ja active Active
- 2014-11-27 CN CN201480074273.9A patent/CN106170552B/zh active Active
- 2014-11-27 EP EP14830514.7A patent/EP3074518B1/en active Active
- 2014-11-27 CA CA2931948A patent/CA2931948C/en active Active
- 2014-11-27 US US15/100,110 patent/US10294492B2/en active Active
- 2014-11-27 ES ES14830514T patent/ES2821782T3/es active Active
-
2016
- 2016-05-29 IL IL245907A patent/IL245907A0/en active IP Right Grant
Also Published As
| Publication number | Publication date |
|---|---|
| DK3074518T3 (da) | 2020-09-28 |
| AU2014356427B2 (en) | 2021-03-04 |
| JP2016537988A (ja) | 2016-12-08 |
| ES2821782T3 (es) | 2021-04-27 |
| US20170022519A1 (en) | 2017-01-26 |
| IL245907A0 (en) | 2016-07-31 |
| CN106170552A (zh) | 2016-11-30 |
| CA2931948A1 (en) | 2015-06-04 |
| AU2014356427A1 (en) | 2016-06-30 |
| US10294492B2 (en) | 2019-05-21 |
| EP3074518A1 (en) | 2016-10-05 |
| EP2878674A1 (en) | 2015-06-03 |
| CA2931948C (en) | 2021-09-07 |
| CN106170552B (zh) | 2020-03-17 |
| JP6694386B2 (ja) | 2020-05-13 |
| EP3074518B1 (en) | 2020-07-08 |
| WO2015078999A1 (en) | 2015-06-04 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| IL245907A0 (en) | Stable episomes based on non-integrating vectors from viruses of the halenti family | |
| GB201318347D0 (en) | Retroviral vectors | |
| AU356417S (en) | Battery | |
| GB201403084D0 (en) | FHS:Smarter contact selectors | |
| PT2969751T (pt) | Dispositivos de propulsão pessoal com equilíbrio melhorado | |
| SG11201507263PA (en) | Rudder | |
| GB201303814D0 (en) | Battery structure | |
| SG11201504818PA (en) | Fast ship | |
| EP2988354A4 (en) | FUEL CELL SYSTEM | |
| TWI561543B (en) | Multy-block copolymer | |
| EP3067906A4 (en) | ELECTROCHEMICAL DEVICE | |
| EP2953200A4 (en) | BATTERY | |
| HK1225860A1 (zh) | 帶有非導電的結構化表面的電池 | |
| EP3073559A4 (en) | FUEL CELL SYSTEM | |
| GB201312803D0 (en) | Cell component | |
| GB201322574D0 (en) | Retroviral peptides | |
| TWM476023U (en) | Small clamp structure | |
| GB201307453D0 (en) | Sail arrangements | |
| IL243792A0 (en) | Meeting arrangement | |
| HUP1300431A2 (en) | Bow | |
| TWM476505U (en) | Contact lens receiving structure | |
| GB201312935D0 (en) | T,b,s | |
| AU2013314V (en) | Anatoki Acca sellowiana | |
| AU2013315V (en) | Kakariki Acca sellowiana | |
| AU2013313V (en) | Kaiteri Acca sellowiana |