PT3013836T - Preparação de reagentes de grignard utilizando um leito fluidizado - Google Patents
Preparação de reagentes de grignard utilizando um leito fluidizadoInfo
- Publication number
- PT3013836T PT3013836T PT14733203T PT14733203T PT3013836T PT 3013836 T PT3013836 T PT 3013836T PT 14733203 T PT14733203 T PT 14733203T PT 14733203 T PT14733203 T PT 14733203T PT 3013836 T PT3013836 T PT 3013836T
- Authority
- PT
- Portugal
- Prior art keywords
- preparation
- fluidized bed
- grignard reagents
- grignard
- reagents
- Prior art date
Links
- 150000004795 grignard reagents Chemical class 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F3/00—Compounds containing elements of Groups 2 or 12 of the Periodic Table
- C07F3/02—Magnesium compounds
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C29/00—Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom not belonging to a six-membered aromatic ring
- C07C29/36—Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom not belonging to a six-membered aromatic ring increasing the number of carbon atoms by reactions with formation of hydroxy groups, which may occur via intermediates being derivatives of hydroxy, e.g. O-metal
- C07C29/38—Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom not belonging to a six-membered aromatic ring increasing the number of carbon atoms by reactions with formation of hydroxy groups, which may occur via intermediates being derivatives of hydroxy, e.g. O-metal by reaction with aldehydes or ketones
- C07C29/40—Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom not belonging to a six-membered aromatic ring increasing the number of carbon atoms by reactions with formation of hydroxy groups, which may occur via intermediates being derivatives of hydroxy, e.g. O-metal by reaction with aldehydes or ketones with compounds containing carbon-to-metal bonds
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C67/00—Preparation of carboxylic acid esters
- C07C67/30—Preparation of carboxylic acid esters by modifying the acid moiety of the ester, such modification not being an introduction of an ester group
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D257/00—Heterocyclic compounds containing rings having four nitrogen atoms as the only ring hetero atoms
- C07D257/02—Heterocyclic compounds containing rings having four nitrogen atoms as the only ring hetero atoms not condensed with other rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F15/00—Compounds containing elements of Groups 8, 9, 10 or 18 of the Periodic Table
- C07F15/0006—Compounds containing elements of Groups 8, 9, 10 or 18 of the Periodic Table compounds of the platinum group
- C07F15/0046—Ruthenium compounds
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
EP13173979 | 2013-06-27 |
Publications (1)
Publication Number | Publication Date |
---|---|
PT3013836T true PT3013836T (pt) | 2018-10-23 |
Family
ID=48699609
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PT14733203T PT3013836T (pt) | 2013-06-27 | 2014-06-27 | Preparação de reagentes de grignard utilizando um leito fluidizado |
Country Status (10)
Country | Link |
---|---|
US (1) | US9550797B2 (pt) |
EP (1) | EP3013836B1 (pt) |
JP (2) | JP6521463B2 (pt) |
CN (1) | CN105377858B (pt) |
AU (1) | AU2014300955B2 (pt) |
BR (1) | BR112015032514B1 (pt) |
CA (1) | CA2914899C (pt) |
ES (1) | ES2683245T3 (pt) |
PT (1) | PT3013836T (pt) |
WO (1) | WO2014207206A1 (pt) |
Families Citing this family (8)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN106279216A (zh) * | 2016-04-06 | 2017-01-04 | 海正化工南通股份有限公司 | 一种邻氯苄基氯化镁的合成办法 |
DE102016206211B4 (de) * | 2016-04-13 | 2018-12-27 | Fraunhofer-Gesellschaft zur Förderung der angewandten Forschung e.V. | Kontinuierliches Verfahren zur Herstellung von Grignard-Addukten und Vorrichtung zu dessen Durchführung |
US20230050880A1 (en) * | 2020-01-27 | 2023-02-16 | Tokuyama Corporation | Method for producing halogenated hydrocarbon magnesium compound and methods for producing tertiary alcohol compound and organosilicon compound |
CN112724164B (zh) * | 2021-01-05 | 2023-07-04 | 兰州康鹏威耳化工有限公司 | 一种格氏试剂的连续制备方法 |
JP7404606B2 (ja) * | 2021-03-19 | 2023-12-26 | 国立大学法人北海道大学 | 有機金属求核剤の製造方法、及び有機金属求核剤を用いる反応方法 |
US20240181422A1 (en) * | 2021-04-22 | 2024-06-06 | Tokuyama Corporation | Method for producing organic compound, and device for producing organic compound |
WO2023152332A1 (en) | 2022-02-10 | 2023-08-17 | Chemium Sprl | Method for the production of organometallic compounds |
CN116178400B (zh) * | 2023-04-28 | 2023-12-05 | 研峰科技(北京)股份有限公司 | 格氏试剂烯丙基溴化镁制备工艺 |
Family Cites Families (16)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US2464685A (en) * | 1946-12-02 | 1949-03-15 | Diamond Alkali Co | Continuous grignard method |
DE1293767B (de) * | 1967-08-26 | 1969-04-30 | Basf Ag | Verfahren zur Herstellung von Grignard-Verbindungen |
US3911037A (en) * | 1973-11-21 | 1975-10-07 | Nalco Chemical Co | Continuous Grignard reactors |
US4105703A (en) * | 1975-06-06 | 1978-08-08 | Oxon Italia S.P.A. | Continuous process for the production of cyclohexyl magnesium halides |
JPS5818323A (ja) * | 1981-07-27 | 1983-02-02 | Sumitomo Chem Co Ltd | アルコ−ル類の製造方法 |
JPS62227498A (ja) * | 1986-03-31 | 1987-10-06 | Kurita Water Ind Ltd | 流動床式嫌気性処理装置 |
DE4027608A1 (de) * | 1990-08-31 | 1992-03-05 | Bayer Ag | Verfahren zur herstellung von 1-chlor-2-(1-chlor-cyclopropyl)-3-(2-chlor-phenyl)-propan-2-ol und/oder 2-(1-chlor-cyclopropyl)-2-(2-chlor-benzyl)-oxiran |
MY119161A (en) * | 1994-04-18 | 2005-04-30 | Novartis Ag | Delta-amino-gamma-hydroxy-omega-aryl-alkanoic acid amides with enzyme especially renin inhibiting activities |
EP0729931B1 (en) * | 1995-03-03 | 1998-08-19 | Dow Corning Corporation | Process for the preparation of 1,5-hexadiene |
US6124500A (en) * | 1998-03-09 | 2000-09-26 | Rohm And Haas Company | Process for synthesizing benzoic acids |
JP2000229982A (ja) * | 1998-12-07 | 2000-08-22 | Mitsubishi Chemicals Corp | ビニルフェニルマグネシウムハライド類の連続的製造方法 |
WO2001009079A1 (de) * | 1999-07-29 | 2001-02-08 | Speedel Pharma Ag | 2-alkyl-5-halogen-pent-4-encarbonsäuren und deren herstellung |
EP1289641A2 (en) * | 2000-05-12 | 2003-03-12 | Upfront Chromatography A/S | A bed adsorption system |
JP4774775B2 (ja) * | 2005-03-23 | 2011-09-14 | 日亜化学工業株式会社 | トリアルキルガリウムの製造方法 |
CN102603775B (zh) * | 2012-01-20 | 2015-08-05 | 上海海嘉诺医药发展股份有限公司 | 一种连续制备格氏试剂的装置及使用该装置进行格氏试剂连续制备的方法 |
US9090537B2 (en) * | 2012-02-17 | 2015-07-28 | Mylan Laboratories Limited | Process for the preparation of aliskiren |
-
2014
- 2014-06-27 JP JP2016522537A patent/JP6521463B2/ja active Active
- 2014-06-27 AU AU2014300955A patent/AU2014300955B2/en active Active
- 2014-06-27 CA CA2914899A patent/CA2914899C/en active Active
- 2014-06-27 PT PT14733203T patent/PT3013836T/pt unknown
- 2014-06-27 WO PCT/EP2014/063704 patent/WO2014207206A1/en active Application Filing
- 2014-06-27 EP EP14733203.5A patent/EP3013836B1/en active Active
- 2014-06-27 US US14/899,445 patent/US9550797B2/en active Active
- 2014-06-27 CN CN201480036803.0A patent/CN105377858B/zh active Active
- 2014-06-27 BR BR112015032514-9A patent/BR112015032514B1/pt active IP Right Grant
- 2014-06-27 ES ES14733203.5T patent/ES2683245T3/es active Active
-
2018
- 2018-12-06 JP JP2018229321A patent/JP2019055987A/ja active Pending
Also Published As
Publication number | Publication date |
---|---|
CA2914899A1 (en) | 2014-12-31 |
EP3013836A1 (en) | 2016-05-04 |
EP3013836B1 (en) | 2018-06-20 |
US9550797B2 (en) | 2017-01-24 |
WO2014207206A1 (en) | 2014-12-31 |
JP2016525504A (ja) | 2016-08-25 |
JP6521463B2 (ja) | 2019-05-29 |
BR112015032514B1 (pt) | 2021-01-26 |
CA2914899C (en) | 2022-08-30 |
CN105377858A (zh) | 2016-03-02 |
CN105377858B (zh) | 2017-11-21 |
AU2014300955B2 (en) | 2019-08-22 |
US20160137669A1 (en) | 2016-05-19 |
AU2014300955A1 (en) | 2016-02-18 |
JP2019055987A (ja) | 2019-04-11 |
BR112015032514A2 (pt) | 2017-07-25 |
ES2683245T3 (es) | 2018-09-25 |
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