PT2900664T - Formas cristalinas de derivados de dihidropirimidina - Google Patents

Formas cristalinas de derivados de dihidropirimidina

Info

Publication number
PT2900664T
PT2900664T PT138410410T PT13841041T PT2900664T PT 2900664 T PT2900664 T PT 2900664T PT 138410410 T PT138410410 T PT 138410410T PT 13841041 T PT13841041 T PT 13841041T PT 2900664 T PT2900664 T PT 2900664T
Authority
PT
Portugal
Prior art keywords
crystalline forms
dihydropyrimidine derivatives
dihydropyrimidine
derivatives
crystalline
Prior art date
Application number
PT138410410T
Other languages
English (en)
Inventor
Ren Qingyun
Goldmann Siegfried
Zhang Yingjun
Liu Xinchang
Wang Chaolei
Wang Tianming
Original Assignee
Sunshine Lake Pharma Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sunshine Lake Pharma Co Ltd filed Critical Sunshine Lake Pharma Co Ltd
Publication of PT2900664T publication Critical patent/PT2900664T/pt

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D417/00Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/04Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/16Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • A61P31/20Antivirals for DNA viruses
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D417/00Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/14Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing three or more hetero rings

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Virology (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Molecular Biology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
PT138410410T 2012-09-27 2013-09-27 Formas cristalinas de derivados de dihidropirimidina PT2900664T (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
CN201210369019 2012-09-27
CN201310117076 2013-04-04

Publications (1)

Publication Number Publication Date
PT2900664T true PT2900664T (pt) 2018-03-02

Family

ID=50355923

Family Applications (1)

Application Number Title Priority Date Filing Date
PT138410410T PT2900664T (pt) 2012-09-27 2013-09-27 Formas cristalinas de derivados de dihidropirimidina

Country Status (21)

Country Link
US (1) US9403814B2 (pt)
EP (1) EP2900664B1 (pt)
JP (1) JP6310923B2 (pt)
KR (1) KR20150060610A (pt)
CN (3) CN104945394B (pt)
AU (1) AU2013324779B2 (pt)
BR (1) BR112015002979B8 (pt)
CA (1) CA2881260C (pt)
DK (1) DK2900664T3 (pt)
ES (1) ES2660642T3 (pt)
HK (1) HK1207081A1 (pt)
HU (1) HUE037285T2 (pt)
MX (1) MX362829B (pt)
MY (1) MY171497A (pt)
PL (1) PL2900664T3 (pt)
PT (1) PT2900664T (pt)
RU (1) RU2646599C2 (pt)
SG (1) SG11201500145TA (pt)
TW (1) TWI561520B (pt)
WO (1) WO2014048355A1 (pt)
ZA (1) ZA201500290B (pt)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SG11201500377UA (en) * 2012-09-10 2015-02-27 Hoffmann La Roche 6-amino acid heteroaryldihydropyrimidines for the treatment and prophylaxis of hepatitis b virus infection
US10253030B2 (en) 2015-11-04 2019-04-09 Qilu Pharmaceutical Co., Ltd. Crystal form, preparation method and intermediate of dihydropyrido ring compound
WO2017198201A1 (en) * 2016-05-19 2017-11-23 Sunshine Lake Pharma Co., Ltd. Crystalline form, salt and complex of dihydropyrimidine derivative, and uses thereof in medicine
CN107722109B (zh) * 2016-08-11 2020-12-18 广东东阳光药业有限公司 作为丙型肝炎病毒抑制剂的晶型
US9856232B1 (en) * 2017-06-20 2018-01-02 King Saud University Dihydropyrimidinone derivatives

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AR043880A1 (es) 2003-04-22 2005-08-17 Solvay Pharm Gmbh Mesilato acido de 4-(4.trans-hidroxiciclohexil) amino-2-fenil-7h-pirrolo (2,3-d) pirimidina y sus formas polimorfas
ES2391597T3 (es) * 2007-06-18 2012-11-28 Sunshine Lake Pharma Co., Ltd Tiazolil dihidropirimidinas sustituidas con bromo-fenilo
WO2008154818A1 (fr) 2007-06-18 2008-12-24 Zhang, Zhongneng Thiazolyl-dihydropyrimidines à substitution fluorophényle
WO2008154819A1 (fr) 2007-06-18 2008-12-24 Zhang, Zhongneng Thiazolyl-dihydropyrimidines à substitution carbéthoxy
CN101328168B (zh) 2007-06-18 2011-09-07 张中能 一种乙氧碳酰基-取代噻唑二氢嘧啶
CN101744823B (zh) * 2008-12-17 2013-06-19 广东东阳光药业有限公司 一种二氢嘧啶类化合物的固体分散体及其药用制剂
WO2010069147A1 (zh) * 2008-12-17 2010-06-24 张中能 二氢嘧啶类化合物、其组合物及其应用

Also Published As

Publication number Publication date
EP2900664B1 (en) 2017-12-13
CA2881260C (en) 2020-10-27
MY171497A (en) 2019-10-15
EP2900664A1 (en) 2015-08-05
EP2900664A4 (en) 2016-03-09
JP6310923B2 (ja) 2018-04-11
CN103724339B (zh) 2015-10-14
BR112015002979B1 (pt) 2020-12-22
WO2014048355A1 (en) 2014-04-03
BR112015002979B8 (pt) 2022-03-03
CN104945394A (zh) 2015-09-30
CN103694234A (zh) 2014-04-02
SG11201500145TA (en) 2015-02-27
PL2900664T3 (pl) 2018-06-29
ZA201500290B (en) 2016-10-26
DK2900664T3 (en) 2018-02-05
RU2015114085A (ru) 2016-11-20
ES2660642T3 (es) 2018-03-23
HK1207081A1 (en) 2016-01-22
CN104945394B (zh) 2017-12-05
RU2646599C2 (ru) 2018-03-06
HUE037285T2 (hu) 2018-08-28
BR112015002979A2 (pt) 2017-07-04
US20150239877A1 (en) 2015-08-27
TWI561520B (en) 2016-12-11
AU2013324779A1 (en) 2015-02-05
MX2015004115A (es) 2016-01-20
US9403814B2 (en) 2016-08-02
CN103724339A (zh) 2014-04-16
MX362829B (es) 2019-02-14
CA2881260A1 (en) 2014-04-03
KR20150060610A (ko) 2015-06-03
AU2013324779B2 (en) 2015-10-08
JP2015531354A (ja) 2015-11-02
TW201412732A (zh) 2014-04-01

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