EP2943500A4 - Crystalline 3-o-fucosyllactose - Google Patents

Crystalline 3-o-fucosyllactose

Info

Publication number
EP2943500A4
EP2943500A4 EP13854558.7A EP13854558A EP2943500A4 EP 2943500 A4 EP2943500 A4 EP 2943500A4 EP 13854558 A EP13854558 A EP 13854558A EP 2943500 A4 EP2943500 A4 EP 2943500A4
Authority
EP
European Patent Office
Prior art keywords
fucosyllactose
crystalline
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
EP13854558.7A
Other languages
German (de)
French (fr)
Other versions
EP2943500A1 (en
EP2943500B1 (en
Inventor
Martin Matwiejuk
Gyula Dekany
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Glycom AS
Original Assignee
Glycom AS
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Glycom AS filed Critical Glycom AS
Publication of EP2943500A1 publication Critical patent/EP2943500A1/en
Publication of EP2943500A4 publication Critical patent/EP2943500A4/en
Application granted granted Critical
Publication of EP2943500B1 publication Critical patent/EP2943500B1/en
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H3/00—Compounds containing only hydrogen atoms and saccharide radicals having only carbon, hydrogen, and oxygen atoms
    • C07H3/06—Oligosaccharides, i.e. having three to five saccharide radicals attached to each other by glycosidic linkages
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
    • A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
    • A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
    • A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
    • A23L33/40—Complete food formulations for specific consumer groups or specific purposes, e.g. infant formula
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H1/00—Processes for the preparation of sugar derivatives
    • C07H1/06—Separation; Purification
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23V—INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
    • A23V2002/00—Food compositions, function of food ingredients or processes for food or foodstuffs
EP13854558.7A 2012-11-13 2013-09-19 Crystalline 3-o-fucosyllactose Active EP2943500B1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DKPA201270696 2012-11-13
PCT/DK2013/050300 WO2014075680A1 (en) 2012-11-13 2013-09-19 Crystalline 3-o-fucosyllactose

Publications (3)

Publication Number Publication Date
EP2943500A1 EP2943500A1 (en) 2015-11-18
EP2943500A4 true EP2943500A4 (en) 2016-06-22
EP2943500B1 EP2943500B1 (en) 2017-11-08

Family

ID=50730610

Family Applications (1)

Application Number Title Priority Date Filing Date
EP13854558.7A Active EP2943500B1 (en) 2012-11-13 2013-09-19 Crystalline 3-o-fucosyllactose

Country Status (4)

Country Link
US (1) US9834574B2 (en)
EP (1) EP2943500B1 (en)
CN (1) CN104812768B (en)
WO (1) WO2014075680A1 (en)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2013139344A1 (en) * 2012-03-20 2013-09-26 Glycom A/S Synthesis of the trisaccharide 3-o-fucosyllactose and intermediates thereof
WO2016086947A1 (en) * 2014-12-05 2016-06-09 Glycom A/S Crystalline difucosyllactose
EP3532787A4 (en) 2016-10-31 2020-07-29 Glycom A/S Method for removing residual organic solvent from a crystalline oligosaccharide
CN110914284A (en) 2017-07-12 2020-03-24 格礼卡姆股份公司 Amorphous mixture comprising neutral mono-or oligosaccharides and acidic non-carbohydrate component
EP3494804A1 (en) 2017-12-08 2019-06-12 Jennewein Biotechnologie GmbH Spray-dried 3-fucosyllactose
EP3494807A1 (en) 2017-12-11 2019-06-12 Jennewein Biotechnologie GmbH Spray-dried sialyllactose
EP3494805A1 (en) 2017-12-08 2019-06-12 Jennewein Biotechnologie GmbH Spray-dried tetrasaccharides
EP3524067A1 (en) 2018-02-08 2019-08-14 Jennewein Biotechnologie GmbH Spray-dried mixture of human milk oligosaccharides
EP3494806A1 (en) 2017-12-08 2019-06-12 Jennewein Biotechnologie GmbH Spray-dried lacto-n-fucopentaose
WO2019110803A1 (en) 2017-12-08 2019-06-13 Jennewein Biotechnologie Gmbh Spray-dried sialyllactose

Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2010070104A1 (en) * 2008-12-19 2010-06-24 Jennewein Biotechnologie Gmbh Synthesis of fucosylated compounds
WO2010115935A1 (en) * 2009-04-07 2010-10-14 Glycom A/S Synthesis of 2 ' -o-fucosyllactose
WO2011150939A1 (en) * 2010-06-01 2011-12-08 Glycom A/S Polymorphs of 2'-o-fucosyllactose and producing thereof
WO2012007585A1 (en) * 2010-07-16 2012-01-19 Glycom A/S Derivatization of oligosaccharides
WO2012112777A2 (en) * 2011-02-16 2012-08-23 Glycosyn LLC Biosynthesis of human milk oligosaccharides in engineered bacteria
WO2013139344A1 (en) * 2012-03-20 2013-09-26 Glycom A/S Synthesis of the trisaccharide 3-o-fucosyllactose and intermediates thereof

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5326752A (en) 1991-11-27 1994-07-05 Glycomed Incorporated Substituted lactose and lactosamine derivatives as cell adhesion inhibitors
US6045854A (en) * 1997-03-31 2000-04-04 Abbott Laboraties Nutritional formulations containing oligosaccharides
IT1392456B1 (en) * 2008-12-18 2012-03-09 Inalco Spa PROCESS FOR THE SYNTHESIS OF L-PHUCOSILATED OLIGOSACCHARIDES AND THEIR NEW INTERMEDIATES 2,3,4-TRIBENZYL-FUCHOSIL-DERIVATIVES.
EP2455387A1 (en) * 2010-11-23 2012-05-23 Nestec S.A. Oligosaccharide mixture and food product comprising this mixture, especially infant formula

Patent Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2010070104A1 (en) * 2008-12-19 2010-06-24 Jennewein Biotechnologie Gmbh Synthesis of fucosylated compounds
WO2010115935A1 (en) * 2009-04-07 2010-10-14 Glycom A/S Synthesis of 2 ' -o-fucosyllactose
WO2011150939A1 (en) * 2010-06-01 2011-12-08 Glycom A/S Polymorphs of 2'-o-fucosyllactose and producing thereof
WO2012007585A1 (en) * 2010-07-16 2012-01-19 Glycom A/S Derivatization of oligosaccharides
WO2012112777A2 (en) * 2011-02-16 2012-08-23 Glycosyn LLC Biosynthesis of human milk oligosaccharides in engineered bacteria
WO2013139344A1 (en) * 2012-03-20 2013-09-26 Glycom A/S Synthesis of the trisaccharide 3-o-fucosyllactose and intermediates thereof

Non-Patent Citations (3)

* Cited by examiner, † Cited by third party
Title
CLANEY L PEREIRA ET AL: "Synthesis of Human Milk Oligosaccharides: 2'- and 3'-Fucosyllactose", HETEROCYCLES: INTERNATIONAL JOURNAL FOR REVIEWS AND COMMUNICATIONS IN HETEROCYCLIC CHEMISTRY,, vol. 84, no. 1, 1 January 2012 (2012-01-01), pages 637 - 655, XP008174628, ISSN: 0385-5414, [retrieved on 20110726], DOI: 10.3987/COM-11-S(P)37 *
FERNANDEZ-MAYORALAS A ET AL: "Synthesis of 3- and 2'-fucosyl-lactose and 3,2'-difucosyl-lactose from partially benzylated lactose derivatives", CARBOHYDRATE RESEARCH, PERGAMON, GB, vol. 154, no. 1, 15 October 1986 (1986-10-15), pages 93 - 101, XP026618813, ISSN: 0008-6215, [retrieved on 19861015], DOI: 10.1016/S0008-6215(00)90025-9 *
See also references of WO2014075680A1 *

Also Published As

Publication number Publication date
US9834574B2 (en) 2017-12-05
CN104812768B (en) 2019-06-21
EP2943500A1 (en) 2015-11-18
EP2943500B1 (en) 2017-11-08
US20150291642A1 (en) 2015-10-15
WO2014075680A1 (en) 2014-05-22
CN104812768A (en) 2015-07-29

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