PT2831246T - Vírus herpes aviário recombinantes multivalentes e vacinas para a imunização de espécies aviárias - Google Patents

Vírus herpes aviário recombinantes multivalentes e vacinas para a imunização de espécies aviárias

Info

Publication number
PT2831246T
PT2831246T PT137131959T PT13713195T PT2831246T PT 2831246 T PT2831246 T PT 2831246T PT 137131959 T PT137131959 T PT 137131959T PT 13713195 T PT13713195 T PT 13713195T PT 2831246 T PT2831246 T PT 2831246T
Authority
PT
Portugal
Prior art keywords
avian
vaccines
immunizing
herpes viruses
multivalent recombinant
Prior art date
Application number
PT137131959T
Other languages
English (en)
Inventor
Fujisawa Ayumi
Kubomura Mayumi
Saeki Sakiko
Saito Shuji
Original Assignee
Ceva Sante Animale
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=48040245&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=PT2831246(T) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Ceva Sante Animale filed Critical Ceva Sante Animale
Publication of PT2831246T publication Critical patent/PT2831246T/pt

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/12—Viral antigens
    • A61K39/245—Herpetoviridae, e.g. herpes simplex virus
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/12—Viral antigens
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/12—Viral antigens
    • A61K39/155—Paramyxoviridae, e.g. parainfluenza virus
    • A61K39/17—Newcastle disease virus
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/20—Antivirals for DNA viruses
    • A61P31/22—Antivirals for DNA viruses for herpes viruses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/04—Immunostimulants
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/85—Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
    • C12N15/86—Viral vectors
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N7/00—Viruses; Bacteriophages; Compositions thereof; Preparation or purification thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
    • A61K2039/525—Virus
    • A61K2039/5256—Virus expressing foreign proteins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/55—Medicinal preparations containing antigens or antibodies characterised by the host/recipient, e.g. newborn with maternal antibodies
    • A61K2039/552—Veterinary vaccine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/70—Multivalent vaccine
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2710/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
    • C12N2710/00011—Details
    • C12N2710/16011—Herpesviridae
    • C12N2710/16311—Mardivirus, e.g. Gallid herpesvirus 2, Marek-like viruses, turkey HV
    • C12N2710/16321—Viruses as such, e.g. new isolates, mutants or their genomic sequences
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2710/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
    • C12N2710/00011—Details
    • C12N2710/16011—Herpesviridae
    • C12N2710/16311—Mardivirus, e.g. Gallid herpesvirus 2, Marek-like viruses, turkey HV
    • C12N2710/16334—Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2710/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
    • C12N2710/00011—Details
    • C12N2710/16011—Herpesviridae
    • C12N2710/16311—Mardivirus, e.g. Gallid herpesvirus 2, Marek-like viruses, turkey HV
    • C12N2710/16341—Use of virus, viral particle or viral elements as a vector
    • C12N2710/16343—Use of virus, viral particle or viral elements as a vector viral genome or elements thereof as genetic vector
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2720/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsRNA viruses
    • C12N2720/00011—Details
    • C12N2720/10011—Birnaviridae
    • C12N2720/10034—Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2760/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses negative-sense
    • C12N2760/00011—Details
    • C12N2760/18011—Paramyxoviridae
    • C12N2760/18111—Avulavirus, e.g. Newcastle disease virus
    • C12N2760/18134—Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Virology (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Immunology (AREA)
  • Genetics & Genomics (AREA)
  • Microbiology (AREA)
  • Engineering & Computer Science (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Zoology (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Mycology (AREA)
  • Epidemiology (AREA)
  • Wood Science & Technology (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Pulmonology (AREA)
  • Physics & Mathematics (AREA)
  • Biophysics (AREA)
  • Plant Pathology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
PT137131959T 2012-03-30 2013-03-29 Vírus herpes aviário recombinantes multivalentes e vacinas para a imunização de espécies aviárias PT2831246T (pt)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP20120305390 EP2644702A1 (en) 2012-03-30 2012-03-30 Multivalent recombinant avian herpes virus and vaccine for immunizing avian species

Publications (1)

Publication Number Publication Date
PT2831246T true PT2831246T (pt) 2017-08-09

Family

ID=48040245

Family Applications (2)

Application Number Title Priority Date Filing Date
PT137131959T PT2831246T (pt) 2012-03-30 2013-03-29 Vírus herpes aviário recombinantes multivalentes e vacinas para a imunização de espécies aviárias
PT171686322T PT3219802T (pt) 2012-03-30 2013-03-29 Vacinas recombinantes multivalentes para herpesvírus aviários e vacinas para imunização de espécies aviárias

Family Applications After (1)

Application Number Title Priority Date Filing Date
PT171686322T PT3219802T (pt) 2012-03-30 2013-03-29 Vacinas recombinantes multivalentes para herpesvírus aviários e vacinas para imunização de espécies aviárias

Country Status (22)

Country Link
US (6) US10251951B2 (pt)
EP (4) EP2644702A1 (pt)
JP (2) JP6505593B2 (pt)
KR (1) KR102070217B1 (pt)
CN (2) CN104364381B (pt)
BR (1) BR112014024094A2 (pt)
CA (1) CA2868132C (pt)
CO (1) CO7160021A2 (pt)
ES (2) ES2807952T3 (pt)
HU (2) HUE050602T2 (pt)
MA (1) MA37446B1 (pt)
MX (1) MX357365B (pt)
MY (1) MY173016A (pt)
PE (2) PE20150334A1 (pt)
PH (2) PH12014502162B1 (pt)
PL (2) PL3219802T3 (pt)
PT (2) PT2831246T (pt)
RU (2) RU2658439C2 (pt)
TN (1) TN2014000392A1 (pt)
UA (1) UA118335C2 (pt)
WO (1) WO2013144355A1 (pt)
ZA (1) ZA201406979B (pt)

Families Citing this family (23)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2644702A1 (en) 2012-03-30 2013-10-02 Ceva Sante Animale Multivalent recombinant avian herpes virus and vaccine for immunizing avian species
EP2845904A1 (en) * 2013-09-06 2015-03-11 Ceva Sante Animale Recombinant Marek's disease viruses and uses thereof
CN104120110B (zh) * 2014-07-11 2017-01-18 中国农业科学院哈尔滨兽医研究所 表达增强型绿色荧光蛋白基因的鸭瘟病毒重组疫苗株及其构建方法和应用
CN104212802B (zh) * 2014-09-25 2017-09-12 中国人民解放军第二军医大学东方肝胆外科医院 一种肿瘤细胞广谱高活性启动子及其用途
AR103245A1 (es) 2014-12-24 2017-04-26 Intervet Int Bv Vacuna vectorial basada en hvt (herpes virus de los pavos) frente a nd (enfermedad de newcastle) - ibd (enfermedad de gumboro) mejorada
WO2017216287A1 (en) 2016-06-17 2017-12-21 Intervet International B.V. Recombinant non-pathogenic marek's disease virus constructs encoding infectious laryngotracheitis virus and infectious bursal disease virus antigens
CN106350475A (zh) * 2016-08-26 2017-01-25 江苏省农业科学院 一种新型火鸡疱疹病毒的细菌人工染色体、构建方法与应用
KR20230170803A (ko) 2016-12-14 2023-12-19 뵈링거 잉겔하임 애니멀 헬스 유에스에이 인코포레이티드 조류 병원체의 다중 항원을 발현하는 재조합 hvt 벡터 및 그를 포함하는 백신
CN106929483B (zh) * 2017-01-19 2020-09-25 北京邦卓生物科技有限公司 表达鸡新城疫病毒f基因的重组火鸡疱疹病毒的构建及其应用
BR112020007213A2 (pt) * 2017-10-12 2020-10-13 Intervet International B.V. construtos de vírus da doença de marek não patogênico recombinante que codificam múltiplos antígenos heterólogos
CN107815469A (zh) * 2017-10-16 2018-03-20 北京市农林科学院 一种重组火鸡疱疹病毒及其制备方法
CN108060141B (zh) * 2017-12-14 2021-05-28 天津瑞普生物技术股份有限公司 Vp2基因和np基因重组腺病毒及其应用
CN109402071B (zh) * 2018-11-08 2021-04-27 中国农业大学 一种表达h9n2亚型禽流感病毒h9蛋白的重组火鸡疱疹病毒
WO2020127964A1 (en) * 2018-12-21 2020-06-25 Ceva Sante Animale Recombinant avian herpes viruses containing multiple foreign genes
EP3902561A1 (en) 2018-12-27 2021-11-03 Ceva Santé Animale Recombinant viruses and the uses thereof
JP2022547975A (ja) 2019-09-11 2022-11-16 ゾエティス・サービシーズ・エルエルシー 鳥病原体の抗原を発現する組換えシチメンチョウヘルペスウイルスベクターおよびそれらの使用
CN110684744A (zh) * 2019-10-22 2020-01-14 青岛易邦生物工程有限公司 一种表达鸡传染性法氏囊病病毒vp2基因的重组火鸡疱疹病毒株
BR112022010825A2 (pt) 2019-12-20 2022-08-23 Intervet Int Bv Vacina de vetor hvt multivalente
MA58717A1 (fr) 2020-06-17 2023-06-28 Boehringer Ingelheim Vetmedica Gmbh Vecteurs hvt recombinants exprimant l'hémagglutinine de la grippe et compositions immunogènes, et leur fabrication et leurs utilisations
CN116457461A (zh) * 2020-10-15 2023-07-18 法国诗华动物保健公司 重组hvt及其用途
US20240058436A1 (en) 2020-12-24 2024-02-22 Intervet Inc. Multivalent hvt vector vaccine
WO2023213946A1 (en) 2022-05-05 2023-11-09 Intervet International B.V. New multivalent hvt vector vaccine
WO2024105245A1 (en) 2022-11-18 2024-05-23 Ceva Sante Animale Recombinant marek's disease virus and uses thereof

Family Cites Families (25)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5965138A (en) 1985-09-06 1999-10-12 Syntro Corporation Recombinant chimeric virus and uses thereof
AU623333B2 (en) 1986-01-27 1992-05-14 Syntro Corporation Attenuated herpesviruses, herpesviruses which include foreign dna encoding an amino acid sequence and vaccine containing same
ES2070997T3 (es) 1989-12-04 1995-06-16 Akzo Nobel Nv Virus de herpes recombinante de pavos y vacunas vector vivas derivadas de los mismos.
JPH06292583A (ja) 1992-03-17 1994-10-21 Nippon Zeon Co Ltd マレック病ウイルス由来の抗原タンパク質、その遺伝子組み換え体、及びそれを用いたワクチン
US6913751B2 (en) * 1992-06-12 2005-07-05 Schering-Plough Veterinary Corporation Recombinant avian herpesvirus useful in vaccine production
RU2120126C1 (ru) * 1994-08-08 1998-10-10 Всероссийский научно-исследовательский ветеринарный институт птицеводства Способ определения лимфоцитов, сенсибилизированных к вакцине против болезни марека
FR2728794B1 (fr) * 1994-12-30 1997-03-21 Rhone Merieux Vaccin recombinant aviaire a base de virus herpes aviaire, notamment contre la maladie de gumboro
FR2728795B1 (fr) * 1994-12-30 1997-03-21 Rhone Merieux Vaccin vivant recombinant aviaire, utilisant comme vecteur un virus herpes aviaire
JPH103635A (ja) * 1996-06-12 1998-01-06 Hitachi Ltd 磁気ヘッドスライダ及びこのスライダを用いた磁気ディスク装置
JPH1028586A (ja) * 1996-07-18 1998-02-03 Nippon Zeon Co Ltd アビポックスウイルスの非必須領域、それを用いた組み換えアビポックスウイルス及びワクチン
EP1026246B1 (en) * 1997-10-03 2006-11-29 Zeon Corporation Avian infectious herpesvirus recombinants and recombinant vaccines prepared with the use of the same
US6764684B2 (en) 2001-09-28 2004-07-20 Zeon Corporation Avian herpesvirus-based recombinant infectious bursal disease vaccine
US6866852B2 (en) * 2002-01-31 2005-03-15 Zeon Corporation Recombinant herpesvirus of turkeys and use thereof
US7029681B2 (en) * 2002-03-08 2006-04-18 Schweitzer Chemical Corporation Multiple and multivalent DNA vaccines in ovo
WO2005093070A1 (ja) 2004-03-29 2005-10-06 Zeon Corporation 組み換えヘルペスウイルス及びその利用
JP2009512421A (ja) * 2005-08-15 2009-03-26 ヴァクシン インコーポレイテッド 非複製性ベクターワクチン投与による鳥類への免疫方法
JP2008228658A (ja) 2007-03-20 2008-10-02 Nippon Zeon Co Ltd 新規なプロモーター、これを有する組み換え七面鳥ヘルペスウイルス、及びこれを利用した家禽用ワクチン
US20080241188A1 (en) * 2007-03-30 2008-10-02 Zeon Corporation Turkey herpesvirus vectored recombinant containing avian influenza genes
JP2009195136A (ja) 2008-02-20 2009-09-03 Nippon Zeon Co Ltd 新規な組換え七面鳥ヘルペスウイルス、及びそれを利用した家禽用ワクチン
BRPI0918806B1 (pt) * 2008-09-05 2019-02-05 Ceva Sante Animale Sa Composição de vacina compreendendo quitosana e antígeno do vírus de doença de newcastle (nvd) adaptada à administração ocular em ave, uso de quitosana e de nvd paraaumentar resposta imune em ave, bem como kit de vacinação de aves
WO2010119112A1 (en) * 2009-04-15 2010-10-21 Ceva Sante Animale Recombinant avian herpes virus vectors and vaccine for immunizing waterfowl species
CA2851658C (en) 2011-10-21 2022-03-15 Intervet International B.V. Recombinant non-pathogenic marek's disease virus constructs encoding infectious laryngotracheitis virus and newcastle disease virus antigens
CA2857025C (en) 2011-11-30 2021-08-03 Merial Limited Recombinant hvt vectors expressing antigens of avian pathogens and uses thereof
EP2644702A1 (en) 2012-03-30 2013-10-02 Ceva Sante Animale Multivalent recombinant avian herpes virus and vaccine for immunizing avian species
EP2845904A1 (en) 2013-09-06 2015-03-11 Ceva Sante Animale Recombinant Marek's disease viruses and uses thereof

Also Published As

Publication number Publication date
EP2831246B1 (en) 2017-05-03
US20180256706A1 (en) 2018-09-13
RU2018116857A3 (pt) 2021-06-08
ZA201406979B (en) 2016-01-27
JP2019080571A (ja) 2019-05-30
ES2636464T3 (es) 2017-10-05
CO7160021A2 (es) 2015-01-15
US20150118250A1 (en) 2015-04-30
WO2013144355A1 (en) 2013-10-03
PL2831246T3 (pl) 2017-10-31
RU2766003C2 (ru) 2022-02-07
HUE035395T2 (en) 2018-05-02
PH12014502162A1 (en) 2014-12-10
PL3219802T3 (pl) 2020-08-24
EP2831246A1 (en) 2015-02-04
US20210401973A1 (en) 2021-12-30
KR102070217B1 (ko) 2020-01-28
PH12014502162B1 (en) 2014-12-10
UA118335C2 (uk) 2019-01-10
PE20191704A1 (es) 2019-11-27
HUE050602T2 (hu) 2020-12-28
PH12019501067A1 (en) 2020-07-06
US10245315B2 (en) 2019-04-02
RU2018116857A (ru) 2018-10-24
US11730807B2 (en) 2023-08-22
EP3708670A1 (en) 2020-09-16
PE20150334A1 (es) 2015-03-25
CA2868132C (en) 2021-08-31
JP6505593B2 (ja) 2019-04-24
MX357365B (es) 2018-07-05
RU2658439C2 (ru) 2018-06-21
RU2014143830A (ru) 2016-05-27
EP2644702A1 (en) 2013-10-02
CA2868132A1 (en) 2013-10-03
MA37446B1 (fr) 2016-10-31
CN104364381B (zh) 2020-07-28
PT3219802T (pt) 2020-07-27
CN111733143A (zh) 2020-10-02
US11123425B2 (en) 2021-09-21
US20180256707A1 (en) 2018-09-13
MA20150281A2 (fr) 2015-08-31
US10251951B2 (en) 2019-04-09
MX2014011754A (es) 2014-11-26
US20200108137A1 (en) 2020-04-09
EP3219802A1 (en) 2017-09-20
TN2014000392A1 (en) 2015-12-21
KR20150003244A (ko) 2015-01-08
BR112014024094A2 (pt) 2017-07-18
JP6845266B2 (ja) 2021-03-17
CN104364381A (zh) 2015-02-18
EP3219802B1 (en) 2020-04-29
MY173016A (en) 2019-12-19
JP2015512633A (ja) 2015-04-30
US20240082390A1 (en) 2024-03-14
US10500270B2 (en) 2019-12-10
ES2807952T3 (es) 2021-02-24

Similar Documents

Publication Publication Date Title
ZA201406979B (en) Multivalent recombinant avian herpes viruses and vaccines for immunizing avian species
IL261204A (en) Influenza virus vaccines and their use
IL262123A (en) Influenza virus vaccines and their uses
HK1218928A1 (zh) 癌症疫苗及接種方法
HK1199211A1 (en) Influenza virus vaccines and uses thereof
EP2998322A4 (en) EPITOPE BASED VACCINE FOR LOW IMMUNOGENICITY PROTEIN AND METHOD FOR PREPARING AND USING SAME
IL229307A0 (en) Inactivated dengue virus vaccine
PT2806891T (pt) Vacinas baseadas no vírus parainfluenza 5
PL2935313T3 (pl) Szczepionki przeciwko wirusowi zapalenia wątroby typu b
PL3073959T3 (pl) Zespól szczepiący do podawania szczepionki do młodej kury
EP2726097A4 (en) HERPES VIRUS VACCINE AND METHOD OF USE
HK1257191A1 (zh) 重組火雞疱疹病毒疫苗及其用途
HK1210475A1 (en) Herpes simplex virus vaccine
HK1220656A1 (zh) 減弱的流感病毒和疫苗
EP2747779A4 (en) VACCINE AGAINST HERPES SIMPLEX VIRUS IN THE FORM OF NANOEMULSION
SG11201510617WA (en) Methods and compositions for dengue virus vaccines
HK1223644A1 (zh) 呼吸道合胞病毒半活疫苗
EP2678043A4 (en) RECOMBINANT MUMPSVIRUS VACCINE
EP3240568A4 (en) Recombinant influenza virus vaccines for influenza and respiratory syncytial virus
ZA201503036B (en) Chimeric vaccine antigens against hepatitis c virus
EP3041503A4 (en) Methods and compositions for viral vectored vaccines
EP2870238A4 (en) COMPOSITIONS AND METHODS ASSOCIATED WITH VIRAL VACCINES
HK1223643A1 (zh) 呼吸道合胞病毒半活疫苗
HK1201283A1 (en) Influenza c virus and vaccine
GB201301119D0 (en) Viral vaccines