PT2722046T - Forma cristalina 1 de 2-((r)-2-metilpirrolidina-2-yl)-1hbenzimidazol- 4-carboxamida - Google Patents

Forma cristalina 1 de 2-((r)-2-metilpirrolidina-2-yl)-1hbenzimidazol- 4-carboxamida

Info

Publication number
PT2722046T
PT2722046T PT141510891T PT14151089T PT2722046T PT 2722046 T PT2722046 T PT 2722046T PT 141510891 T PT141510891 T PT 141510891T PT 14151089 T PT14151089 T PT 14151089T PT 2722046 T PT2722046 T PT 2722046T
Authority
PT
Portugal
Prior art keywords
methylpyrrolidin
benzimidazole
crystalline form
carboxamide crystalline
carboxamide
Prior art date
Application number
PT141510891T
Other languages
English (en)
Inventor
Kolaczkowski Lawrence
Original Assignee
Abbvie Ireland Unlimited Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=40210712&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=PT2722046(T) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Abbvie Ireland Unlimited Co filed Critical Abbvie Ireland Unlimited Co
Publication of PT2722046T publication Critical patent/PT2722046T/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/4164—1,3-Diazoles
    • A61K31/4184—1,3-Diazoles condensed with carbocyclic rings, e.g. benzimidazoles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B2200/00—Indexing scheme relating to specific properties of organic compounds
    • C07B2200/13—Crystalline forms, e.g. polymorphs

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
PT141510891T 2007-10-12 2008-10-10 Forma cristalina 1 de 2-((r)-2-metilpirrolidina-2-yl)-1hbenzimidazol- 4-carboxamida PT2722046T (pt)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US97964307P 2007-10-12 2007-10-12

Publications (1)

Publication Number Publication Date
PT2722046T true PT2722046T (pt) 2017-03-15

Family

ID=40210712

Family Applications (1)

Application Number Title Priority Date Filing Date
PT141510891T PT2722046T (pt) 2007-10-12 2008-10-10 Forma cristalina 1 de 2-((r)-2-metilpirrolidina-2-yl)-1hbenzimidazol- 4-carboxamida

Country Status (27)

Country Link
US (4) US8372987B2 (pt)
EP (2) EP2212327A1 (pt)
JP (4) JP2011500589A (pt)
KR (2) KR20160039312A (pt)
CN (2) CN101821270A (pt)
AU (1) AU2008310781B2 (pt)
BR (1) BRPI0816221A8 (pt)
CA (2) CA3006332A1 (pt)
CO (1) CO6280493A2 (pt)
CR (1) CR11368A (pt)
DK (1) DK2722046T3 (pt)
DO (1) DOP2010000099A (pt)
EC (1) ECSP10010150A (pt)
ES (1) ES2620299T3 (pt)
GT (1) GT201000080A (pt)
MX (1) MX350019B (pt)
MY (1) MY156691A (pt)
NZ (1) NZ583209A (pt)
PA (1) PA8798401A1 (pt)
PL (1) PL2722046T3 (pt)
PT (1) PT2722046T (pt)
RU (2) RU2476434C2 (pt)
SG (1) SG185297A1 (pt)
TW (1) TWI422588B (pt)
UA (2) UA101961C2 (pt)
WO (1) WO2009049111A1 (pt)
ZA (1) ZA201002090B (pt)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA3006332A1 (en) 2007-10-12 2009-04-16 Abbvie Ireland Unlimited Company 2-((r)-2-methylpyrrolidin-2-yl)-1h-benzimidazole-4-carboxamide crystalline form 1
CA2696423A1 (en) 2007-10-12 2009-04-16 Guidong Zhu 2-((r)-2-methylpyrrolidin-2-yl)-1h-benzimidazole-4-carboxamide crystalline form 2
TW201702218A (zh) 2014-12-12 2017-01-16 美國杰克森實驗室 關於治療癌症、自體免疫疾病及神經退化性疾病之組合物及方法
CN105130961B (zh) * 2015-08-06 2018-02-16 苏州晶云药物科技有限公司 Abt‑888的晶型b及其制备方法和应用
CN106995436A (zh) * 2016-01-25 2017-08-01 重庆医药工业研究院有限责任公司 一种维利帕尼晶型a及其制备方法
US20190092756A1 (en) * 2016-03-09 2019-03-28 Crystal Pharmatech Co., Ltd. Crystalline form a of 2-[(2r)-2-methyl-2-pyrrolidyl]-1h-benzimidazole-7-carboxamide dihydrochloride and preparation method thereof
EP3275434B1 (en) 2016-07-27 2020-08-26 Sandoz Ag An extended release oral dosage form

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2396079A1 (en) * 2000-01-07 2001-07-19 Transform Pharmaceuticals, Inc. High-throughput formation, identification, and analysis of diverse solid-forms
EP1298125A1 (en) * 2001-09-26 2003-04-02 Aventis Pharma S.A. Substituted benzimidazole compounds and their use for the treatment of cancer
TWI375673B (en) * 2005-04-11 2012-11-01 Abbott Lab 1h-benzimidazole-4-carboxamides substituted with a quaternary carbon at the 2-position are potent parp inhibitors
CA3006332A1 (en) 2007-10-12 2009-04-16 Abbvie Ireland Unlimited Company 2-((r)-2-methylpyrrolidin-2-yl)-1h-benzimidazole-4-carboxamide crystalline form 1
CA2696423A1 (en) * 2007-10-12 2009-04-16 Guidong Zhu 2-((r)-2-methylpyrrolidin-2-yl)-1h-benzimidazole-4-carboxamide crystalline form 2

Also Published As

Publication number Publication date
JP2019001811A (ja) 2019-01-10
ES2620299T3 (es) 2017-06-28
GT201000080A (es) 2012-04-03
DK2722046T3 (en) 2017-03-20
CO6280493A2 (es) 2011-05-20
TW200932747A (en) 2009-08-01
MY156691A (en) 2016-03-15
SG185297A1 (en) 2012-11-29
CA3006332A1 (en) 2009-04-16
MX2010003772A (es) 2010-04-21
WO2009049111A1 (en) 2009-04-16
US20140024838A1 (en) 2014-01-23
AU2008310781A1 (en) 2009-04-16
US20130123317A1 (en) 2013-05-16
KR20160039312A (ko) 2016-04-08
US8372987B2 (en) 2013-02-12
JP2011500589A (ja) 2011-01-06
ZA201002090B (en) 2011-11-30
US8835647B2 (en) 2014-09-16
PA8798401A1 (es) 2009-05-15
DOP2010000099A (es) 2017-04-30
BRPI0816221A2 (pt) 2015-06-16
JP2017071618A (ja) 2017-04-13
US20090099245A1 (en) 2009-04-16
MX350019B (es) 2016-12-09
EP2722046B1 (en) 2016-12-21
EP2722046A1 (en) 2014-04-23
UA113277C2 (xx) 2017-01-10
ECSP10010150A (es) 2010-06-29
BRPI0816221A8 (pt) 2015-09-22
TWI422588B (zh) 2014-01-11
RU2476434C2 (ru) 2013-02-27
CA2696424C (en) 2018-07-10
US9580410B2 (en) 2017-02-28
UA101961C2 (en) 2013-05-27
CA2696424A1 (en) 2009-04-16
NZ583209A (en) 2012-06-29
RU2010116397A (ru) 2011-11-20
JP2014237659A (ja) 2014-12-18
CN101821270A (zh) 2010-09-01
PL2722046T3 (pl) 2017-06-30
KR20100090769A (ko) 2010-08-17
US20150148392A1 (en) 2015-05-28
RU2012147692A (ru) 2014-05-20
EP2212327A1 (en) 2010-08-04
CR11368A (es) 2010-10-25
CN105367554A (zh) 2016-03-02
AU2008310781B2 (en) 2013-03-28

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