PT2632926E - Forma cristalina de 13-[(n-terc-butoxicarbonil)-2¿-o-hexanoil- 3-fenilisoserinil]-10-desacetilbacatina iii - Google Patents

Forma cristalina de 13-[(n-terc-butoxicarbonil)-2¿-o-hexanoil- 3-fenilisoserinil]-10-desacetilbacatina iii Download PDF

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Publication number
PT2632926E
PT2632926E PT117767582T PT11776758T PT2632926E PT 2632926 E PT2632926 E PT 2632926E PT 117767582 T PT117767582 T PT 117767582T PT 11776758 T PT11776758 T PT 11776758T PT 2632926 E PT2632926 E PT 2632926E
Authority
PT
Portugal
Prior art keywords
phenylisoserinyl
hexanoyl
butoxycarbonyl
tert
crystalline form
Prior art date
Application number
PT117767582T
Other languages
English (en)
Inventor
Daniele Ciceri
Andrea Gambini
Maurizio Ricotti
Nicola Sardone
Original Assignee
Indena Spa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Indena Spa filed Critical Indena Spa
Publication of PT2632926E publication Critical patent/PT2632926E/pt

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Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D305/00Heterocyclic compounds containing four-membered rings having one oxygen atom as the only ring hetero atoms
    • C07D305/14Heterocyclic compounds containing four-membered rings having one oxygen atom as the only ring hetero atoms condensed with carbocyclic rings or ring systems
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/335Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/337Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having four-membered rings, e.g. taxol
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • A61P35/04Antineoplastic agents specific for metastasis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/14Vasoprotectives; Antihaemorrhoidals; Drugs for varicose therapy; Capillary stabilisers
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D305/00Heterocyclic compounds containing four-membered rings having one oxygen atom as the only ring hetero atoms
    • C07D305/02Heterocyclic compounds containing four-membered rings having one oxygen atom as the only ring hetero atoms not condensed with other rings
    • C07D305/04Heterocyclic compounds containing four-membered rings having one oxygen atom as the only ring hetero atoms not condensed with other rings having no double bonds between ring members or between ring members and non-ring members
    • C07D305/06Heterocyclic compounds containing four-membered rings having one oxygen atom as the only ring hetero atoms not condensed with other rings having no double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to the ring atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D493/00Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system
    • C07D493/02Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system in which the condensed system contains two hetero rings
    • C07D493/04Ortho-condensed systems

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Epidemiology (AREA)
  • Vascular Medicine (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Oncology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Epoxy Compounds (AREA)
PT117767582T 2010-10-29 2011-10-27 Forma cristalina de 13-[(n-terc-butoxicarbonil)-2¿-o-hexanoil- 3-fenilisoserinil]-10-desacetilbacatina iii PT2632926E (pt)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP10189373A EP2447268A1 (en) 2010-10-29 2010-10-29 Crystalline form of 13-[(N-tert-butoxycarbonyl)-2'-O-hexanoyl-3-phenylisoserinyl]-10-deacetylbaccatin III

Publications (1)

Publication Number Publication Date
PT2632926E true PT2632926E (pt) 2015-02-09

Family

ID=43886731

Family Applications (1)

Application Number Title Priority Date Filing Date
PT117767582T PT2632926E (pt) 2010-10-29 2011-10-27 Forma cristalina de 13-[(n-terc-butoxicarbonil)-2¿-o-hexanoil- 3-fenilisoserinil]-10-desacetilbacatina iii

Country Status (16)

Country Link
US (1) US9062018B2 (pt)
EP (2) EP2447268A1 (pt)
JP (1) JP5744215B2 (pt)
KR (2) KR20130086618A (pt)
CN (1) CN103209983B (pt)
AR (1) AR083588A1 (pt)
AU (1) AU2011322572B2 (pt)
CA (1) CA2814907C (pt)
DK (1) DK2632926T3 (pt)
ES (1) ES2528374T3 (pt)
MX (1) MX2013004722A (pt)
PL (1) PL2632926T3 (pt)
PT (1) PT2632926E (pt)
RU (1) RU2546661C2 (pt)
SI (1) SI2632926T1 (pt)
WO (1) WO2012055952A1 (pt)

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1295229C (zh) * 2001-11-29 2007-01-17 第一制药株式会社 紫杉烷衍生物的结晶及其制备方法
CN105879114A (zh) * 2005-02-18 2016-08-24 阿布拉西斯生物科学公司 用于整合入医疗装置的疏水性改善的药物
EP2330101A1 (en) 2006-10-20 2011-06-08 Scinopharm Singapore Pte, Ltd. Process for making crystalline docetaxel
KR20100133475A (ko) 2008-04-10 2010-12-21 아브락시스 바이오사이언스, 엘엘씨 소수성 탁산 유도체의 조성물 그의 용도

Also Published As

Publication number Publication date
AU2011322572B2 (en) 2015-02-19
KR101577177B1 (ko) 2015-12-14
JP2013540798A (ja) 2013-11-07
DK2632926T3 (en) 2015-01-12
KR20130086618A (ko) 2013-08-02
EP2447268A1 (en) 2012-05-02
JP5744215B2 (ja) 2015-07-08
MX2013004722A (es) 2013-08-29
RU2546661C2 (ru) 2015-04-10
WO2012055952A1 (en) 2012-05-03
CN103209983A (zh) 2013-07-17
RU2013124011A (ru) 2014-12-10
AU2011322572A1 (en) 2013-05-02
PL2632926T3 (pl) 2015-04-30
CA2814907A1 (en) 2012-05-03
US20140303240A1 (en) 2014-10-09
ES2528374T3 (es) 2015-02-09
US9062018B2 (en) 2015-06-23
CA2814907C (en) 2015-02-03
CN103209983B (zh) 2016-04-13
EP2632926B1 (en) 2014-12-10
EP2632926A1 (en) 2013-09-04
SI2632926T1 (sl) 2015-03-31
KR20150099614A (ko) 2015-08-31
AR083588A1 (es) 2013-03-06

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