PT2611444E - Compostos heterociclilo como ligandos de recetores de histamina h3 - Google Patents
Compostos heterociclilo como ligandos de recetores de histamina h3 Download PDFInfo
- Publication number
- PT2611444E PT2611444E PT108033960T PT10803396T PT2611444E PT 2611444 E PT2611444 E PT 2611444E PT 108033960 T PT108033960 T PT 108033960T PT 10803396 T PT10803396 T PT 10803396T PT 2611444 E PT2611444 E PT 2611444E
- Authority
- PT
- Portugal
- Prior art keywords
- histamine
- receptor ligands
- heterocyclyl compounds
- heterocyclyl
- compounds
- Prior art date
Links
- 102000004384 Histamine H3 receptors Human genes 0.000 title 1
- 108090000981 Histamine H3 receptors Proteins 0.000 title 1
- 125000000623 heterocyclic group Chemical group 0.000 title 1
- 239000003446 ligand Substances 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D513/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00
- C07D513/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00 in which the condensed system contains two hetero rings
- C07D513/04—Ortho-condensed systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
- C07D417/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/496—Non-condensed piperazines containing further heterocyclic rings, e.g. rifampin, thiothixene or sparfloxacin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P23/00—Anaesthetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/20—Hypnotics; Sedatives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/04—Anorexiants; Antiobesity agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
- C07D413/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
- C07D417/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D498/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D498/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
- C07D498/04—Ortho-condensed systems
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Biomedical Technology (AREA)
- Neurosurgery (AREA)
- Neurology (AREA)
- Anesthesiology (AREA)
- Obesity (AREA)
- Hematology (AREA)
- Diabetes (AREA)
- Hospice & Palliative Care (AREA)
- Psychiatry (AREA)
- Child & Adolescent Psychology (AREA)
- Pain & Pain Management (AREA)
- Epidemiology (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Peptides Or Proteins (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| IN2551CH2010 | 2010-09-02 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| PT2611444E true PT2611444E (pt) | 2016-02-04 |
Family
ID=43608695
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PT108033960T PT2611444E (pt) | 2010-09-02 | 2010-11-15 | Compostos heterociclilo como ligandos de recetores de histamina h3 |
Country Status (27)
| Country | Link |
|---|---|
| US (1) | US8912179B2 (pt) |
| EP (1) | EP2611444B1 (pt) |
| JP (1) | JP5650329B2 (pt) |
| KR (1) | KR101538239B1 (pt) |
| CN (1) | CN103079566B (pt) |
| AU (1) | AU2010360038B2 (pt) |
| BR (1) | BR112013005084A2 (pt) |
| CA (1) | CA2812970C (pt) |
| CY (1) | CY1117096T1 (pt) |
| DK (1) | DK2611444T3 (pt) |
| EA (1) | EA022746B1 (pt) |
| ES (1) | ES2558531T3 (pt) |
| HK (1) | HK1180955A1 (pt) |
| HR (1) | HRP20151380T1 (pt) |
| HU (1) | HUE028435T2 (pt) |
| IL (1) | IL224652A (pt) |
| ME (1) | ME02320B (pt) |
| MX (1) | MX354852B (pt) |
| NZ (1) | NZ607658A (pt) |
| PL (1) | PL2611444T3 (pt) |
| PT (1) | PT2611444E (pt) |
| RS (1) | RS54514B1 (pt) |
| SG (1) | SG188212A1 (pt) |
| SI (1) | SI2611444T1 (pt) |
| SM (1) | SMT201600012B (pt) |
| WO (1) | WO2012029070A1 (pt) |
| ZA (1) | ZA201301143B (pt) |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DK2888243T3 (en) * | 2012-08-23 | 2016-09-26 | Suven Life Sciences Ltd | ACRYLAMIDE COMPOUNDS AS HISTAMINE H3 RECEPTOR LIGANDS |
| CN104530088A (zh) * | 2014-12-08 | 2015-04-22 | 苏州施亚生物科技有限公司 | 2-氨基-6,7-二氢-5H-噻唑并[5,4-b]吡啶-4-羧酸叔丁酯及其衍生物,以及它们的合成方法 |
| EP3378477A1 (en) * | 2017-03-21 | 2018-09-26 | BIOPROJET Pharma | New therapeutical use of h3-ligands |
| WO2019086141A1 (en) | 2017-11-02 | 2019-05-09 | Aicuris Gmbh & Co. Kg | Novel, highly active amino-thiazole substituted indole-2-carboxamides active against the hepatitis b virus (hbv) |
Family Cites Families (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4695575A (en) | 1984-11-13 | 1987-09-22 | Janssen Pharmaceutica, N.V. | 4-[(bicycle heterocyclyl)-methyl and -hetero]-piperidines |
| PH23995A (en) | 1984-01-09 | 1990-02-09 | Janssen Pharmaceutica Nv | 4((bicycle heterocyclyl)-methyl and hetero)piperidines |
| DE60234453D1 (de) | 2001-07-02 | 2009-12-31 | High Point Pharmaceuticals Llc | Substituierte piperazin- und diazepanderivate zur verwendung als histamin h3 rezeptormodulatoren |
| CN1694704A (zh) | 2002-09-06 | 2005-11-09 | 詹森药业有限公司 | （1h－苯并咪唑－2－基）－（哌嗪基）－甲酮衍生物及其相关化合物作为组胺h4受体拮抗剂用于治疗炎性和过敏性疾病 |
| EA200700254A1 (ru) * | 2004-07-16 | 2007-06-29 | Янссен Фармацевтика Н. В. | Димерные производные пипередина |
| WO2006008260A1 (en) * | 2004-07-16 | 2006-01-26 | Janssen Pharmaceutica N.V. | Dimeric piperidine derivatives |
| US20080161289A1 (en) * | 2005-03-14 | 2008-07-03 | Glaxo Group Limited | Fused Thiazole Derivatives Having Affinity for the Histamine H3 Receptor |
| CN101410385B (zh) * | 2006-03-28 | 2011-08-24 | 高点制药有限责任公司 | 具有组胺h3受体活性的苯并噻唑类 |
| EP2049548A1 (en) * | 2006-07-27 | 2009-04-22 | UCB Pharma, S.A. | Fused oxazoles & thiazoles as histamine h3- receptor ligands |
| US8314119B2 (en) * | 2006-11-06 | 2012-11-20 | Abbvie Inc. | Azaadamantane derivatives and methods of use |
| US7557101B2 (en) * | 2006-12-08 | 2009-07-07 | Hoffman-La Roche Inc. | 4,5,6,7-tetrahydro-thieno[3,2-c] pyridine derivatives |
| US20080146559A1 (en) * | 2006-12-08 | 2008-06-19 | Li Chen | 4,5,6,7-Tetrahydro-Thieno [2,3-C] Pyridine Derivatives |
| CA2710474A1 (en) * | 2008-01-24 | 2009-07-30 | Ucb Pharma, S.A. | Compounds comprising a cyclobutoxy group |
| WO2010026113A1 (en) | 2008-09-03 | 2010-03-11 | Evotec Neurosciences Gmbh | Acyl- and sufonyl tetrahydronaphthyridines and aza derivatives thereof as histamine h3 receptor antagonists |
-
2010
- 2010-11-15 JP JP2013526597A patent/JP5650329B2/ja not_active Expired - Fee Related
- 2010-11-15 US US13/818,152 patent/US8912179B2/en not_active Expired - Fee Related
- 2010-11-15 WO PCT/IN2010/000740 patent/WO2012029070A1/en active Application Filing
- 2010-11-15 PL PL10803396T patent/PL2611444T3/pl unknown
- 2010-11-15 MX MX2013001988A patent/MX354852B/es active IP Right Grant
- 2010-11-15 AU AU2010360038A patent/AU2010360038B2/en not_active Ceased
- 2010-11-15 DK DK10803396.0T patent/DK2611444T3/en active
- 2010-11-15 CA CA2812970A patent/CA2812970C/en not_active Expired - Fee Related
- 2010-11-15 SG SG2013010921A patent/SG188212A1/en unknown
- 2010-11-15 ES ES10803396.0T patent/ES2558531T3/es active Active
- 2010-11-15 ME MEP-2015-216A patent/ME02320B/me unknown
- 2010-11-15 BR BR112013005084-5A patent/BR112013005084A2/pt not_active Application Discontinuation
- 2010-11-15 CN CN201080068911.8A patent/CN103079566B/zh not_active Expired - Fee Related
- 2010-11-15 PT PT108033960T patent/PT2611444E/pt unknown
- 2010-11-15 EA EA201390327A patent/EA022746B1/ru not_active IP Right Cessation
- 2010-11-15 RS RS20150868A patent/RS54514B1/en unknown
- 2010-11-15 KR KR1020137005890A patent/KR101538239B1/ko active IP Right Grant
- 2010-11-15 SI SI201031083T patent/SI2611444T1/sl unknown
- 2010-11-15 EP EP10803396.0A patent/EP2611444B1/en active Active
- 2010-11-15 HU HUE10803396A patent/HUE028435T2/en unknown
-
2012
- 2012-12-24 NZ NZ607658A patent/NZ607658A/en not_active IP Right Cessation
-
2013
- 2013-02-10 IL IL224652A patent/IL224652A/en not_active IP Right Cessation
- 2013-02-11 ZA ZA2013/01143A patent/ZA201301143B/en unknown
- 2013-07-15 HK HK13108284.3A patent/HK1180955A1/xx not_active IP Right Cessation
-
2015
- 2015-12-15 HR HRP20151380TT patent/HRP20151380T1/hr unknown
- 2015-12-30 CY CY20151101205T patent/CY1117096T1/el unknown
-
2016
- 2016-01-14 SM SM201600012T patent/SMT201600012B/it unknown
Also Published As
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| HRP20181788T1 (hr) | Supstituirani spojevi piridinon-piridinil | |
| AP3391A (en) | 2-Amino-4-arylthiazole compounds as TROA1 antagonists | |
| PL2611300T3 (pl) | Podstawione skondensowane pochodne dihydropirymidynonów | |
| EP2709609A4 (en) | HETEROCYCLIC COMPOUNDS | |
| HK1187613A1 (en) | Compounds as histamine h3 receptor ligands h3 | |
| HK1203938A1 (en) | Novel 2h-indazoles as ep2 receptor antagonists ep2 2h- | |
| AP3307A (en) | Heteroaryl compounds as 5-HT4 receptor ligands | |
| HK1180955A1 (en) | Heterocyclyl compounds as histamine h3 receptor ligands h3 | |
| HK1204620A1 (en) | Acrylamide compounds as histamine h3 receptor ligands h3 | |
| GB2501403B (en) | 3-arylethynyl substituted quinazolinone compounds | |
| ZA201409244B (en) | Acrylamide compounds as histamine h3 receptor ligands | |
| GB201015784D0 (en) | Anti-cancer compounds |