PT2605764E - Composições para o tratamento de cancro - Google Patents
Composições para o tratamento de cancro Download PDFInfo
- Publication number
- PT2605764E PT2605764E PT117493932T PT11749393T PT2605764E PT 2605764 E PT2605764 E PT 2605764E PT 117493932 T PT117493932 T PT 117493932T PT 11749393 T PT11749393 T PT 11749393T PT 2605764 E PT2605764 E PT 2605764E
- Authority
- PT
- Portugal
- Prior art keywords
- cancer
- compositions
- treatment
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/4353—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems
- A61K31/437—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems the heterocyclic ring system containing a five-membered ring having nitrogen as a ring hetero atom, e.g. indolizine, beta-carboline
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/47—Quinolines; Isoquinolines
- A61K31/4738—Quinolines; Isoquinolines ortho- or peri-condensed with heterocyclic ring systems
- A61K31/4745—Quinolines; Isoquinolines ortho- or peri-condensed with heterocyclic ring systems condensed with ring systems having nitrogen as a ring hetero atom, e.g. phenantrolines
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
- A61K31/517—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with carbocyclic ring systems, e.g. quinazoline, perimidine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
- C07K16/2863—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against receptors for growth factors, growth regulators
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
- C07K2317/24—Immunoglobulins specific features characterized by taxonomic origin containing regions, domains or residues from different species, e.g. chimeric, humanized or veneered
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
- C07K2317/76—Antagonist effect on antigen, e.g. neutralization or inhibition of binding
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Immunology (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Microbiology (AREA)
- Mycology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- Genetics & Genomics (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US37429610P | 2010-08-17 | 2010-08-17 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| PT2605764E true PT2605764E (pt) | 2015-06-02 |
Family
ID=44532840
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PT117493932T PT2605764E (pt) | 2010-08-17 | 2011-08-16 | Composições para o tratamento de cancro |
Country Status (26)
| Country | Link |
|---|---|
| US (1) | US8709419B2 (pt) |
| EP (1) | EP2605764B1 (pt) |
| JP (1) | JP5758003B2 (pt) |
| KR (1) | KR101475167B1 (pt) |
| CN (1) | CN103153292B (pt) |
| AR (1) | AR082691A1 (pt) |
| AU (1) | AU2011290818B2 (pt) |
| BR (1) | BR112013003530A2 (pt) |
| CA (1) | CA2807222A1 (pt) |
| DK (1) | DK2605764T3 (pt) |
| ES (1) | ES2535000T3 (pt) |
| HR (1) | HRP20150648T1 (pt) |
| HU (1) | HUE025187T2 (pt) |
| IL (1) | IL224395A (pt) |
| MX (1) | MX349878B (pt) |
| MY (1) | MY161288A (pt) |
| NZ (1) | NZ606251A (pt) |
| PL (1) | PL2605764T3 (pt) |
| PT (1) | PT2605764E (pt) |
| RS (1) | RS53959B1 (pt) |
| RU (1) | RU2607596C2 (pt) |
| SG (1) | SG188207A1 (pt) |
| SI (1) | SI2605764T1 (pt) |
| TW (1) | TWI530287B (pt) |
| WO (1) | WO2012022724A1 (pt) |
| ZA (1) | ZA201300967B (pt) |
Families Citing this family (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US8709419B2 (en) | 2010-08-17 | 2014-04-29 | Hoffmann-La Roche, Inc. | Combination therapy |
| US9295669B2 (en) | 2010-12-14 | 2016-03-29 | Hoffman La-Roche Inc. | Combination therapy for proliferative disorders |
| MA34948B1 (fr) | 2011-02-07 | 2014-03-01 | Plexxikon Inc | Composes et procedes de modulation de kinase, et leurs indications |
| US9216170B2 (en) | 2012-03-19 | 2015-12-22 | Hoffmann-La Roche Inc. | Combination therapy for proliferative disorders |
| BR112015003418A2 (pt) | 2012-08-17 | 2017-07-04 | Hoffmann La Roche | produto farmacêutico, conjunto, métodos para estender a duração da resposta ao tratamento, de retardar ou prevenir o desenvolvimento de resistência ao tratamento, para a seleção de uma terapia e para otimizar a eficácia terapêutica. |
| US10179135B2 (en) | 2014-01-24 | 2019-01-15 | Lam Therapeutics, Inc. | Apilimod compositions and methods for using same |
| WO2015156674A2 (en) * | 2014-04-10 | 2015-10-15 | Stichting Het Nederlands Kanker Instituut | Method for treating cancer |
| EP3581184B1 (en) * | 2014-11-07 | 2021-02-24 | AI Therapeutics, Inc. | Apilimod for use in the treatment of renal cancer |
| US11040027B2 (en) | 2017-01-17 | 2021-06-22 | Heparegenix Gmbh | Protein kinase inhibitors for promoting liver regeneration or reducing or preventing hepatocyte death |
| WO2019195959A1 (en) * | 2018-04-08 | 2019-10-17 | Cothera Biosciences, Inc. | Combination therapy for cancers with braf mutation |
Family Cites Families (35)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5516807A (en) * | 1994-10-25 | 1996-05-14 | Warner-Lambert Company | Method for treating vascular proliferative disorders following balloon angioplasty |
| US20030229112A1 (en) | 2000-01-26 | 2003-12-11 | Houghton Peter J. | Combination therapy for cancer |
| US6545010B2 (en) | 2000-03-17 | 2003-04-08 | Aventis Pharma S.A. | Composition comprising camptothecin or a camptothecin derivative and a platin derivative for the treatment of cancer |
| CA2408710C (en) | 2000-05-15 | 2010-01-26 | Celgene Corp. | Compositions and methods for the treatment of colorectal cancer |
| AU1172502A (en) | 2000-10-13 | 2002-04-22 | Vion Pharmaceuticals Inc | Modified prodrug forms of ap/amp |
| GB0123400D0 (en) | 2001-09-28 | 2001-11-21 | Novartis Ag | Organic compounds |
| CA2383259A1 (en) | 2002-04-23 | 2003-10-23 | Celator Technologies Inc. | Synergistic compositions |
| US20080193445A1 (en) | 2002-01-18 | 2008-08-14 | Liliane Goetsch | Novel anti-IGF-IR antibodies and uses thereof |
| JP2005534623A (ja) * | 2002-04-08 | 2005-11-17 | スミスクライン ビーチャム コーポレーション | Ｅｒｂファミリーの阻害剤並びにｒａｆ及び／又はｒａｓ阻害剤を投与することを含む癌の治療法 |
| US8007826B2 (en) | 2003-12-11 | 2011-08-30 | Acorda Therapeutics, Inc. | Sustained release aminopyridine composition |
| PL1696920T3 (pl) | 2003-12-19 | 2015-03-31 | Plexxikon Inc | Związki i sposoby opracowywania modulatorów Ret |
| US20070281041A1 (en) | 2004-03-02 | 2007-12-06 | Introgen Therapeutics, Inc. | Compositions and Methods Involving MDA-7 for the Treatment of Cancer |
| TW200533339A (en) | 2004-03-16 | 2005-10-16 | Bristol Myers Squibb Co | Therapeutic synergy of anti-cancer compounds |
| KR100851271B1 (ko) * | 2004-06-03 | 2008-08-08 | 에프. 호프만-라 로슈 아게 | 이리노테칸 （ｃｐｔ-１１） 및 ｅｇｆｒ-억제제를 이용한치료 |
| JP2008501651A (ja) * | 2004-06-03 | 2008-01-24 | エフ．ホフマン−ラ ロシュ アーゲー | イリノテカン（ｃｐｔ−１１）およびｅｇｆｒ阻害剤を用いた処置 |
| BRPI0610440A2 (pt) | 2005-04-14 | 2010-06-22 | Merck Patent Gmbh | terapia com anticorpo anti-egfr baseada em um maior número de cópias do gene egfr em tecidos de tumores |
| US20070059310A1 (en) | 2005-05-03 | 2007-03-15 | Karel Steven J | Therapeutic combination compositions and methods of using same |
| US20060257400A1 (en) | 2005-05-13 | 2006-11-16 | Bristol-Myers Squibb Company | Combination therapy |
| BRPI0611863B1 (pt) * | 2005-06-22 | 2021-11-23 | Plexxikon, Inc | Composto, bem como composição e kit compreendendo o mesmo, composto intermediário na preparação do mesmo, método para tratamento e uso do mesmo |
| KR101109437B1 (ko) | 2005-12-01 | 2012-01-31 | 에프. 호프만-라 로슈 아게 | 항암제로서 사용하기 위한 ｐ53 및 ｍｄｍ2 단백질 간상호작용의 저해제로서의 2,4,5-트리페닐 이미다졸린유도체 |
| JP2009535372A (ja) | 2006-05-03 | 2009-10-01 | バイエル・シエーリング・ファーマ アクチエンゲゼルシャフト | 抗ｅｄｂフィブロネクチンドメイン抗体ｌ１９−ｓｉｐ及び抗−ｅｇｆｒ−抗体の組合せ |
| KR20090071603A (ko) * | 2006-09-19 | 2009-07-01 | 노파르티스 아게 | Ｒａｆ 억제제에 대한 표적 조절, 효능, 진단 및/또는 예후의 바이오마커 |
| PE20121126A1 (es) * | 2006-12-21 | 2012-08-24 | Plexxikon Inc | Compuestos pirrolo [2,3-b] piridinas como moduladores de quinasa |
| EP2133095A4 (en) | 2007-03-05 | 2012-09-26 | Kyowa Hakko Kirin Co Ltd | PHARMACEUTICAL COMPOSITION |
| EP2821488B1 (en) | 2007-08-01 | 2016-07-27 | Idera Pharmaceuticals, Inc. | Novel synthetic agonists of TLR9 |
| AU2009210654A1 (en) * | 2008-02-08 | 2009-08-13 | Poniard Pharmaceuticals, Inc. | Use of picoplatin and bevacizumab to treat colorectal cancer |
| US8354444B2 (en) | 2008-09-18 | 2013-01-15 | Hoffmann-La Roche Inc. | Substituted pyrrolidine-2-carboxamides |
| AR078033A1 (es) | 2009-04-03 | 2011-10-12 | Plexxikon Inc | Una dispersion solida, que contiene al compuesto {3-[5-(4-(cloro-fenil)-1h-pirrolo[2,3-b]piridina-3-carbonil]-2,4-difluor-fenil}-amida del acido propano-1-sulfonico, composiciones y formulaciones que comprenden a dicha dispersion solida; metodos para fabricar dicha dispersion solida, formas 1 y 2 de |
| EP2419727A1 (en) | 2009-04-14 | 2012-02-22 | Schering Corporation | Interferon-alfa sensitivity biomarkers |
| US8535887B2 (en) | 2009-05-21 | 2013-09-17 | Merck Sharp & Dohme Corp. | Genetic markers associated with interferon-alpha response |
| WO2011028540A1 (en) | 2009-08-24 | 2011-03-10 | Genentech, Inc. | Determining sensitivity of cells to b-raf inhibitor treatment by detecting kras mutation and rtk expression levels |
| US8709419B2 (en) | 2010-08-17 | 2014-04-29 | Hoffmann-La Roche, Inc. | Combination therapy |
| US20120045433A1 (en) | 2010-08-17 | 2012-02-23 | Kapil Dhingra | Combination therapy |
| US9295669B2 (en) | 2010-12-14 | 2016-03-29 | Hoffman La-Roche Inc. | Combination therapy for proliferative disorders |
| US9216170B2 (en) | 2012-03-19 | 2015-12-22 | Hoffmann-La Roche Inc. | Combination therapy for proliferative disorders |
-
2011
- 2011-08-10 US US13/206,557 patent/US8709419B2/en active Active
- 2011-08-15 TW TW100129120A patent/TWI530287B/zh not_active IP Right Cessation
- 2011-08-15 AR ARP110102961A patent/AR082691A1/es unknown
- 2011-08-16 JP JP2013524438A patent/JP5758003B2/ja active Active
- 2011-08-16 BR BR112013003530A patent/BR112013003530A2/pt not_active Application Discontinuation
- 2011-08-16 ES ES11749393.2T patent/ES2535000T3/es active Active
- 2011-08-16 CN CN201180050102.9A patent/CN103153292B/zh active Active
- 2011-08-16 SG SG2013010640A patent/SG188207A1/en unknown
- 2011-08-16 MX MX2013001518A patent/MX349878B/es active IP Right Grant
- 2011-08-16 RS RS20150260A patent/RS53959B1/en unknown
- 2011-08-16 NZ NZ606251A patent/NZ606251A/en not_active IP Right Cessation
- 2011-08-16 CA CA2807222A patent/CA2807222A1/en not_active Abandoned
- 2011-08-16 MY MYPI2013700258A patent/MY161288A/en unknown
- 2011-08-16 AU AU2011290818A patent/AU2011290818B2/en not_active Ceased
- 2011-08-16 RU RU2013110124A patent/RU2607596C2/ru not_active IP Right Cessation
- 2011-08-16 DK DK11749393.2T patent/DK2605764T3/en active
- 2011-08-16 HU HUE11749393A patent/HUE025187T2/en unknown
- 2011-08-16 WO PCT/EP2011/064050 patent/WO2012022724A1/en active Application Filing
- 2011-08-16 EP EP11749393.2A patent/EP2605764B1/en active Active
- 2011-08-16 PL PL11749393T patent/PL2605764T3/pl unknown
- 2011-08-16 KR KR1020137006567A patent/KR101475167B1/ko active IP Right Grant
- 2011-08-16 SI SI201130486T patent/SI2605764T1/sl unknown
- 2011-08-16 PT PT117493932T patent/PT2605764E/pt unknown
-
2013
- 2013-01-24 IL IL224395A patent/IL224395A/en active IP Right Grant
- 2013-02-05 ZA ZA2013/00967A patent/ZA201300967B/en unknown
-
2015
- 2015-06-16 HR HRP20150648TT patent/HRP20150648T1/hr unknown
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