PT2590949E - Método para o fabrico de quinolina-3-carboxamidas - Google Patents
Método para o fabrico de quinolina-3-carboxamidas Download PDFInfo
- Publication number
- PT2590949E PT2590949E PT117324210T PT11732421T PT2590949E PT 2590949 E PT2590949 E PT 2590949E PT 117324210 T PT117324210 T PT 117324210T PT 11732421 T PT11732421 T PT 11732421T PT 2590949 E PT2590949 E PT 2590949E
- Authority
- PT
- Portugal
- Prior art keywords
- carboxamides
- quinoline
- manufacturing
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
- C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
- C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D215/48—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
- C07D215/54—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen attached in position 3
- C07D215/56—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen attached in position 3 with oxygen atoms in position 4
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/47—Quinolines; Isoquinolines
- A61K31/4704—2-Quinolinones, e.g. carbostyril
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Immunology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Epidemiology (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Quinoline Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US36284910P | 2010-07-09 | 2010-07-09 | |
| EP10169162 | 2010-07-09 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| PT2590949E true PT2590949E (pt) | 2016-03-07 |
Family
ID=43348982
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PT117324210T PT2590949E (pt) | 2010-07-09 | 2011-07-07 | Método para o fabrico de quinolina-3-carboxamidas |
Country Status (21)
| Country | Link |
|---|---|
| US (1) | US8871936B2 (pt) |
| EP (1) | EP2590949B1 (pt) |
| JP (1) | JP5881691B2 (pt) |
| KR (1) | KR101855195B1 (pt) |
| CN (1) | CN103119023B (pt) |
| AU (1) | AU2011275720B2 (pt) |
| BR (1) | BR112012033465A2 (pt) |
| CA (1) | CA2802006C (pt) |
| DK (1) | DK2590949T5 (pt) |
| EA (1) | EA021171B1 (pt) |
| ES (1) | ES2563208T3 (pt) |
| HK (1) | HK1183864A1 (pt) |
| IL (1) | IL223583A (pt) |
| MX (1) | MX2013000288A (pt) |
| NZ (1) | NZ604176A (pt) |
| PL (1) | PL2590949T3 (pt) |
| PT (1) | PT2590949E (pt) |
| SG (1) | SG186430A1 (pt) |
| UA (1) | UA108381C2 (pt) |
| WO (1) | WO2012004338A1 (pt) |
| ZA (1) | ZA201209370B (pt) |
Families Citing this family (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103626701A (zh) * | 2012-08-28 | 2014-03-12 | 天津药物研究院 | 一种制备喹啉衍生物的方法 |
| CN103626702A (zh) * | 2012-08-30 | 2014-03-12 | 天津药物研究院 | 一种制备喹啉酮衍生物的方法 |
| CN108358842A (zh) * | 2014-08-28 | 2018-08-03 | 杭州普晒医药科技有限公司 | 他喹莫德的晶型及其制备方法、其药物组合物和用途 |
| CN107108510B (zh) | 2014-09-23 | 2020-10-23 | 活跃生物技术有限公司 | 用于治疗多发性骨髓瘤的喹啉甲酰胺 |
| EP3180005B1 (en) | 2014-11-19 | 2017-12-27 | Active Biotech AB | Quinoline carboxamides for use in the treatment of leukemia |
| KR101807124B1 (ko) * | 2015-12-02 | 2017-12-07 | 현대자동차 주식회사 | 연료전지차량의 비상 운전 제어 방법 |
| CN115209881A (zh) | 2020-03-03 | 2022-10-18 | 活跃生物技术有限公司 | 用于组合疗法的他喹莫德或其药学上可接受的盐 |
| CN111732540B (zh) * | 2020-07-20 | 2020-11-13 | 湖南速博生物技术有限公司 | 一种罗喹美克的制备方法 |
| IL300068A (en) | 2020-07-23 | 2023-03-01 | Univ Erasmus Med Ct Rotterdam | S100 proteins as new therapeutic targets in myeloproliferative catalysis |
| JP2024503372A (ja) | 2021-01-18 | 2024-01-25 | アクティブ バイオテック エイビー | 骨髄異形成症候群の処置における使用のためのタスキニモドまたはその薬学的に許容される塩 |
| IL308542A (en) | 2021-05-25 | 2024-01-01 | Active Biotech Ab | Multiparticles of tesquinimod and their use |
| WO2023275248A1 (en) | 2021-07-02 | 2023-01-05 | Active Biotech Ab | A pharmaceutical product containing tasquinimod and a method for assessing the purity of said product |
| KR20230149402A (ko) | 2022-04-20 | 2023-10-27 | 목포대학교산학협력단 | 판막 석회화 예방 또는 치료용 조성물 |
Family Cites Families (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3868379A (en) | 1972-04-28 | 1975-02-25 | Warner Lambert Co | Heterocyclic amides of 4-hydroxy-2H-1-benzothiopyran-3-carboxylic acid 1,1-dioxide |
| US3769292A (en) * | 1972-04-28 | 1973-10-30 | Warner Lambert Co | N-(pyridyl)2h 1-benzothiopyran-3-carboxamide-4-hydroxy 1,1-dioxides |
| AT345847B (de) * | 1974-11-08 | 1978-10-10 | Thomae Gmbh Dr K | Verfahren zur herstellung neuer 4-hydroxy-2h- naphtho- (2,1-e)-1,2-thiazin-3-carboxamid-1,1-dioxid und deren salze |
| US4786644A (en) * | 1987-11-27 | 1988-11-22 | Hoechst-Roussel Pharmaceuticals Inc. | 1-aryl-3-quinolinecarboxamide |
| US5912349A (en) | 1997-01-31 | 1999-06-15 | Pharmacia & Upjohn Company | Process for the preparation of roquinimex |
| US6077851A (en) | 1998-04-27 | 2000-06-20 | Active Biotech Ab | Quinoline derivatives |
| SE9801474D0 (sv) | 1998-04-27 | 1998-04-27 | Active Biotech Ab | Quinoline Derivatives |
| US6133285A (en) | 1998-07-15 | 2000-10-17 | Active Biotech Ab | Quinoline derivatives |
| US7560557B2 (en) * | 2002-06-12 | 2009-07-14 | Active Biotech Ag | Process for the manufacture of quinoline derivatives |
| US6875869B2 (en) | 2002-06-12 | 2005-04-05 | Active Biotech Ab | Process for the manufacture of quinoline derivatives |
| SE0201778D0 (sv) * | 2002-06-12 | 2002-06-12 | Active Biotech Ab | Process for the manufacture of quinoline derivatives |
| JP2011512357A (ja) * | 2008-02-15 | 2011-04-21 | メルク・シャープ・エンド・ドーム・コーポレイション | 縮合ピリドンｍ１受容体ポジティブアロステリックモジュレーター |
| EP2276740B8 (en) * | 2008-04-28 | 2015-02-18 | Actavis Group PCT ehf | Improved process for preparing quinoline-3-carboxamide derivatives |
-
2011
- 2011-07-07 JP JP2013517387A patent/JP5881691B2/ja active Active
- 2011-07-07 AU AU2011275720A patent/AU2011275720B2/en active Active
- 2011-07-07 KR KR1020137001660A patent/KR101855195B1/ko active IP Right Grant
- 2011-07-07 MX MX2013000288A patent/MX2013000288A/es active IP Right Grant
- 2011-07-07 ES ES11732421.0T patent/ES2563208T3/es active Active
- 2011-07-07 PT PT117324210T patent/PT2590949E/pt unknown
- 2011-07-07 SG SG2012094371A patent/SG186430A1/en unknown
- 2011-07-07 EA EA201300103A patent/EA021171B1/ru not_active IP Right Cessation
- 2011-07-07 BR BR112012033465A patent/BR112012033465A2/pt not_active Application Discontinuation
- 2011-07-07 CA CA2802006A patent/CA2802006C/en active Active
- 2011-07-07 UA UAA201300947A patent/UA108381C2/uk unknown
- 2011-07-07 US US13/809,233 patent/US8871936B2/en active Active
- 2011-07-07 WO PCT/EP2011/061490 patent/WO2012004338A1/en active Application Filing
- 2011-07-07 PL PL11732421T patent/PL2590949T3/pl unknown
- 2011-07-07 DK DK11732421.0T patent/DK2590949T5/en active
- 2011-07-07 EP EP11732421.0A patent/EP2590949B1/en active Active
- 2011-07-07 CN CN201180033827.7A patent/CN103119023B/zh active Active
- 2011-07-07 NZ NZ604176A patent/NZ604176A/en not_active IP Right Cessation
-
2012
- 2012-12-11 ZA ZA2012/09370A patent/ZA201209370B/en unknown
- 2012-12-12 IL IL223583A patent/IL223583A/en active IP Right Grant
-
2013
- 2013-10-03 HK HK13111271.2A patent/HK1183864A1/zh unknown
Also Published As
| Publication number | Publication date |
|---|---|
| ZA201209370B (en) | 2014-03-26 |
| NZ604176A (en) | 2014-10-31 |
| EA201300103A1 (ru) | 2013-06-28 |
| AU2011275720A1 (en) | 2013-01-10 |
| EP2590949A1 (en) | 2013-05-15 |
| DK2590949T3 (en) | 2016-02-29 |
| EP2590949B1 (en) | 2015-11-25 |
| US20130109860A1 (en) | 2013-05-02 |
| CN103119023B (zh) | 2014-12-24 |
| ES2563208T3 (es) | 2016-03-11 |
| CA2802006A1 (en) | 2012-01-12 |
| WO2012004338A1 (en) | 2012-01-12 |
| IL223583A (en) | 2016-03-31 |
| SG186430A1 (en) | 2013-01-30 |
| US8871936B2 (en) | 2014-10-28 |
| CA2802006C (en) | 2018-09-25 |
| AU2011275720B2 (en) | 2015-05-14 |
| KR20130091730A (ko) | 2013-08-19 |
| JP2013529672A (ja) | 2013-07-22 |
| KR101855195B1 (ko) | 2018-05-08 |
| DK2590949T5 (en) | 2016-05-23 |
| CN103119023A (zh) | 2013-05-22 |
| UA108381C2 (uk) | 2015-04-27 |
| EA021171B1 (ru) | 2015-04-30 |
| HK1183864A1 (zh) | 2014-01-10 |
| BR112012033465A2 (pt) | 2017-06-20 |
| JP5881691B2 (ja) | 2016-03-09 |
| MX2013000288A (es) | 2013-05-22 |
| PL2590949T3 (pl) | 2016-06-30 |
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