PT2518509E - Diagnóstico molecular e classificação de melanoma maligno com base em marcadores seleccionados da listagem que consiste em rgs1, ncoa3, spp1, phip - Google Patents

Diagnóstico molecular e classificação de melanoma maligno com base em marcadores seleccionados da listagem que consiste em rgs1, ncoa3, spp1, phip Download PDF

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Publication number
PT2518509E
PT2518509E PT121776843T PT12177684T PT2518509E PT 2518509 E PT2518509 E PT 2518509E PT 121776843 T PT121776843 T PT 121776843T PT 12177684 T PT12177684 T PT 12177684T PT 2518509 E PT2518509 E PT 2518509E
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Portugal
Prior art keywords
ncoa3
rgs1
phip
spp1
classification
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PT121776843T
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English (en)
Inventor
Mohammed Kashani-Sabet
Christopher Haqq
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Univ California
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Publication of PT2518509E publication Critical patent/PT2518509E/pt

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    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6883Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
    • C12Q1/6886Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material for cancer
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/574Immunoassay; Biospecific binding assay; Materials therefor for cancer
    • G01N33/57407Specifically defined cancers
    • G01N33/5743Specifically defined cancers of skin, e.g. melanoma
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/574Immunoassay; Biospecific binding assay; Materials therefor for cancer
    • G01N33/57484Immunoassay; Biospecific binding assay; Materials therefor for cancer involving compounds serving as markers for tumor, cancer, neoplasia, e.g. cellular determinants, receptors, heat shock/stress proteins, A-protein, oligosaccharides, metabolites
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6893Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids related to diseases not provided for elsewhere
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00Oligonucleotides characterized by their use
    • C12Q2600/112Disease subtyping, staging or classification
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00Oligonucleotides characterized by their use
    • C12Q2600/118Prognosis of disease development
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00Oligonucleotides characterized by their use
    • C12Q2600/136Screening for pharmacological compounds
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00Detection or diagnosis of diseases
    • G01N2800/56Staging of a disease; Further complications associated with the disease

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Urology & Nephrology (AREA)
  • Hematology (AREA)
  • Pathology (AREA)
  • Analytical Chemistry (AREA)
  • Oncology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Physics & Mathematics (AREA)
  • Cell Biology (AREA)
  • Organic Chemistry (AREA)
  • Hospice & Palliative Care (AREA)
  • General Physics & Mathematics (AREA)
  • Food Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Biophysics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
PT121776843T 2008-03-05 2009-03-05 Diagnóstico molecular e classificação de melanoma maligno com base em marcadores seleccionados da listagem que consiste em rgs1, ncoa3, spp1, phip PT2518509E (pt)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US3410908P 2008-03-05 2008-03-05

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Publication Number Publication Date
PT2518509E true PT2518509E (pt) 2014-09-01

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Application Number Title Priority Date Filing Date
PT121776843T PT2518509E (pt) 2008-03-05 2009-03-05 Diagnóstico molecular e classificação de melanoma maligno com base em marcadores seleccionados da listagem que consiste em rgs1, ncoa3, spp1, phip
PT97184378T PT2257810E (pt) 2008-03-05 2009-03-05 Diagnóstico molecular e classificação de melanoma maligno

Family Applications After (1)

Application Number Title Priority Date Filing Date
PT97184378T PT2257810E (pt) 2008-03-05 2009-03-05 Diagnóstico molecular e classificação de melanoma maligno

Country Status (10)

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US (2) US8492102B2 (pt)
EP (2) EP2518509B1 (pt)
CN (1) CN102037361A (pt)
AU (1) AU2009221778A1 (pt)
CA (1) CA2716357A1 (pt)
DK (2) DK2518509T3 (pt)
ES (2) ES2489840T3 (pt)
NZ (1) NZ587750A (pt)
PT (2) PT2518509E (pt)
WO (1) WO2009111661A1 (pt)

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DK2518509T3 (da) 2008-03-05 2014-08-18 Univ California Molekylær prognose og klassificering af malignt melanom på basis af markører fra listen RGS1, NCOA3, SPP1, PHIP
CN102089444A (zh) 2008-05-14 2011-06-08 德玛泰克国际公司 利用核酸分析方法来诊断黑素瘤和太阳能雀斑
US8859213B2 (en) 2010-04-20 2014-10-14 Cornell University Method for diagnosing melanocytic proliferations
CN102998448A (zh) * 2011-09-09 2013-03-27 上海市计划生育科学研究所 来源于前列腺分泌液中的前列腺癌标记物
US20160222457A1 (en) 2012-11-14 2016-08-04 Mayo Foundation For Medical Education And Research Methods and materials for identifying malignant skin lesions
WO2014158696A1 (en) * 2013-03-14 2014-10-02 Castle Biosciences, Inc. Methods for predicting risk of metastasis in cutaneous melanoma
AU2014235380B2 (en) * 2013-03-15 2020-03-19 Myriad Mypath, Llc Genes and gene signatures for diagnosis and treatment of melanoma
CN103472234B (zh) * 2013-07-05 2015-01-07 武汉三鹰生物技术有限公司 一种酶联免疫检测及制备方法
EP4250299A3 (en) * 2014-07-02 2023-12-06 Myriad myPath, LLC Genes and gene signatures for diagnosis and treatment of melanoma
US20170275700A1 (en) 2014-08-14 2017-09-28 Mayo Foundation For Medical Education And Research Methods and materials for identifying metastatic malignant skin lesions and treating skin cancer
CA3023506A1 (en) 2016-05-10 2017-11-16 Mayo Foundation For Medical Education And Research Methods and materials for staging and treating skin cancer
US11976332B2 (en) 2018-02-14 2024-05-07 Dermtech, Inc. Gene classifiers and uses thereof in non-melanoma skin cancers
AU2020247911A1 (en) 2019-03-26 2021-11-11 Dermtech, Inc. Novel gene classifiers and uses thereof in skin cancers
CN110438229A (zh) * 2019-08-01 2019-11-12 上海交通大学 一种胃癌预后诊断生物标记物及其诊断试剂盒
CN113293214A (zh) * 2021-06-17 2021-08-24 深圳华因康基因科技有限公司 一种检测神经母细胞瘤复发转移基因wnt2扩增的引物探针及其应用
CN115786504B (zh) * 2022-08-31 2023-09-19 中国人民解放军总医院京南医疗区 Hspa4抑制剂在治疗黑素瘤中的应用

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Also Published As

Publication number Publication date
EP2257810A4 (en) 2011-06-08
PT2257810E (pt) 2013-08-22
DK2518509T3 (da) 2014-08-18
US20110123997A1 (en) 2011-05-26
EP2518509A2 (en) 2012-10-31
EP2257810A1 (en) 2010-12-08
AU2009221778A1 (en) 2009-09-11
CN102037361A (zh) 2011-04-27
EP2518509A3 (en) 2013-01-23
EP2257810B1 (en) 2013-06-05
US20130344481A1 (en) 2013-12-26
DK2257810T3 (da) 2013-07-15
NZ587750A (en) 2012-10-26
WO2009111661A9 (en) 2010-06-10
EP2518509B1 (en) 2014-05-14
CA2716357A1 (en) 2009-09-11
US8492102B2 (en) 2013-07-23
ES2424329T3 (es) 2013-10-01
ES2489840T3 (es) 2014-09-02
WO2009111661A1 (en) 2009-09-11

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