PT2417251E - Método de purificação do vírus da raiva - Google Patents

Método de purificação do vírus da raiva Download PDF

Info

Publication number
PT2417251E
PT2417251E PT107232290T PT10723229T PT2417251E PT 2417251 E PT2417251 E PT 2417251E PT 107232290 T PT107232290 T PT 107232290T PT 10723229 T PT10723229 T PT 10723229T PT 2417251 E PT2417251 E PT 2417251E
Authority
PT
Portugal
Prior art keywords
purifying
rabies virus
rabies
virus
Prior art date
Application number
PT107232290T
Other languages
English (en)
Inventor
Virginie Fabre
Céline Rocca
Pierre Riffard
Eric Calvosa
Original Assignee
Sanofi Pasteur
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sanofi Pasteur filed Critical Sanofi Pasteur
Publication of PT2417251E publication Critical patent/PT2417251E/pt

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/12—Viral antigens
    • A61K39/205—Rhabdoviridae, e.g. rabies virus
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N7/00—Viruses; Bacteriophages; Compositions thereof; Preparation or purification thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/12—Viral antigens
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2760/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses negative-sense
    • C12N2760/00011—Details
    • C12N2760/20011—Rhabdoviridae
    • C12N2760/20111—Lyssavirus, e.g. rabies virus
    • C12N2760/20134—Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2760/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses negative-sense
    • C12N2760/00011—Details
    • C12N2760/20011—Rhabdoviridae
    • C12N2760/20111—Lyssavirus, e.g. rabies virus
    • C12N2760/20151—Methods of production or purification of viral material

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Virology (AREA)
  • Organic Chemistry (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Genetics & Genomics (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Immunology (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • Biomedical Technology (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Mycology (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Molecular Biology (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
PT107232290T 2009-04-08 2010-04-08 Método de purificação do vírus da raiva PT2417251E (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR0952310A FR2944292B1 (fr) 2009-04-08 2009-04-08 Procede de purification du virus rabique
US23139409P 2009-08-05 2009-08-05

Publications (1)

Publication Number Publication Date
PT2417251E true PT2417251E (pt) 2014-09-09

Family

ID=41219745

Family Applications (1)

Application Number Title Priority Date Filing Date
PT107232290T PT2417251E (pt) 2009-04-08 2010-04-08 Método de purificação do vírus da raiva

Country Status (12)

Country Link
US (2) US8961997B2 (pt)
EP (2) EP2806024B1 (pt)
CN (2) CN102282253B (pt)
AU (1) AU2010233602B2 (pt)
CA (1) CA2757895A1 (pt)
DK (1) DK2417251T3 (pt)
ES (1) ES2498726T3 (pt)
FR (1) FR2944292B1 (pt)
MX (1) MX368161B (pt)
PL (1) PL2417251T3 (pt)
PT (1) PT2417251E (pt)
WO (1) WO2010116096A1 (pt)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2944292B1 (fr) 2009-04-08 2013-08-23 Sanofi Pasteur Procede de purification du virus rabique
US8557253B2 (en) 2009-10-07 2013-10-15 Sanofi Pasteur Sa Stabilizing excipient for inactivated whole virus vaccine
US20120156757A1 (en) * 2010-12-15 2012-06-21 Millipore Corporation Purification of immunogens using a non-polysaccharide matrix
KR20150118155A (ko) * 2013-02-22 2015-10-21 에이전시 포 사이언스, 테크놀로지 앤드 리서치 음성 하전된 입자들을 갖는 바이러스 제제들의 크로마토그래피 정제
WO2018161858A1 (en) 2017-03-06 2018-09-13 Guangzhou Realbenefitspot Pharmaceutical Co., Ltd. Methods of producing and characterizing virus vaccine and virus vaccine composition
EP3420076B1 (en) * 2017-03-06 2024-02-21 Guangzhou Realbenefitspot Pharmaceutical Co., Ltd. Methods of producing and characterizing virus vaccine and virus vaccine composition
CN108434106B (zh) * 2017-04-25 2021-07-30 广州瑞贝斯药业有限公司 一种狂犬病疫苗的冻干制剂
CN107384877B (zh) * 2017-08-18 2020-09-08 深圳源兴基因技术有限公司 一种慢病毒的纯化方法
CN111527202B (zh) * 2017-11-08 2024-03-29 蓝天免疫疗法有限责任公司 So3色谱在病毒纯化方法中的应用
TW202043466A (zh) 2019-01-25 2020-12-01 德商百靈佳殷格翰國際股份有限公司 編碼ccl21之重組棒狀病毒
CN111088223A (zh) * 2019-12-27 2020-05-01 华农（肇庆）生物产业技术研究院有限公司 一种df-1细胞的微载体悬浮培养方法及应用
CN111467486A (zh) * 2020-04-29 2020-07-31 江苏金迪克生物技术股份有限公司 一种狂犬病疫苗的纯化方法
CN113117067A (zh) * 2021-04-16 2021-07-16 深圳市卫光生物制品股份有限公司 一种用于去除狂犬病疫苗制品中鸡胚宿主蛋白的方法
CN114015659B (zh) * 2021-10-18 2024-02-27 江苏金迪克生物技术股份有限公司 一种狂犬病疫苗的纯化方法

Family Cites Families (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4525349A (en) * 1981-12-29 1985-06-25 Societe Anonyme Dite: Institut Merueux Process for the large-scale production of a vaccine against poliomyelitis and the resulting vaccine
JPS6147187A (ja) * 1984-08-10 1986-03-07 Chemo Sero Therapeut Res Inst 狂犬病ウイルスの精製方法
US4664912A (en) * 1984-10-01 1987-05-12 Wiktor Tadeusz J Process for the large scale production of rabies vaccine
FR2633832B1 (fr) 1988-07-05 1991-05-31 Virbac Vaccin antirabique avirulent
FR2693655B1 (fr) 1992-07-20 1994-10-14 Virbac Vaccin antirabique avirulent.
FR2737730B1 (fr) * 1995-08-10 1997-09-05 Pasteur Merieux Serums Vacc Procede de purification de virus par chromatographie
MY125870A (en) 1997-07-25 2006-08-30 Alza Corp Osmotic delivery system flow modulator apparatus and method
FR2801900B1 (fr) 1999-12-03 2004-02-27 Pasteur Merieux Serums Vacc Methode de production de cellules animales adherentes
DE60208854T2 (de) 2001-04-23 2006-08-17 Akzo Nobel N.V. Attenuierte rekombinante stabile Tollwutvirusmutanten und Lebendimpfstoffe
CN1816619A (zh) 2003-06-18 2006-08-09 昂尼克斯药物公司 纯化病毒的方法
CA2557800A1 (en) 2004-03-22 2005-10-06 Yossef Raviv Cellular and viral inactivation
WO2006108707A1 (en) 2005-04-11 2006-10-19 Crucell Holland B.V. Virus purification using ultrafiltration
EP1724338A1 (en) * 2005-05-19 2006-11-22 Crucell Holland B.V. Methods for the production of a whole-inactivated West Nile Virus vaccine
WO2008071774A1 (en) * 2006-12-14 2008-06-19 Cytos Biotechnology Ag Purification process for coat protein of rna bacteriophages
CN101270350A (zh) 2008-03-05 2008-09-24 辽宁依生生物制药有限公司 一种提取狂犬病病毒的方法
FR2944292B1 (fr) 2009-04-08 2013-08-23 Sanofi Pasteur Procede de purification du virus rabique
CN101623497A (zh) * 2009-08-05 2010-01-13 长春卫尔赛生物药业有限公司 一种狂犬病疫苗去除残余dna的方法

Also Published As

Publication number Publication date
EP2806024A1 (fr) 2014-11-26
CN102282253A (zh) 2011-12-14
EP2417251B1 (fr) 2014-07-02
AU2010233602B2 (en) 2015-07-23
AU2010233602A1 (en) 2011-11-03
PL2417251T3 (pl) 2014-11-28
US8961997B2 (en) 2015-02-24
CA2757895A1 (en) 2010-10-14
CN105012947B (zh) 2018-11-06
EP2417251A1 (fr) 2012-02-15
US9750800B2 (en) 2017-09-05
EP2806024B1 (fr) 2016-07-20
US20100260798A1 (en) 2010-10-14
CN102282253B (zh) 2015-06-17
FR2944292A1 (fr) 2010-10-15
CN105012947A (zh) 2015-11-04
ES2498726T3 (es) 2014-09-25
MX368161B (es) 2019-09-20
FR2944292B1 (fr) 2013-08-23
WO2010116096A1 (fr) 2010-10-14
US20150216963A1 (en) 2015-08-06
DK2417251T3 (da) 2014-09-15

Similar Documents

Publication Publication Date Title
PT2417251E (pt) Método de purificação do vírus da raiva
PL3192874T3 (pl) Oczyszczanie wirusa
ZA201001480B (en) Method for producing flu virus
EP2334328A4 (en) METHOD FOR CLEANING VIRUSES
SI2504334T1 (sl) Postopek čiščenja (4,6-diamino-2-(1-(2-fluorobenzil)-1H-pirazolo-(3,4-b)piridin-3-il)piri midin-5-il)metilkarbamata
GB0822068D0 (en) Methods for virus design
HK1176946A1 (zh) 純化免疫球蛋白溶液的方法
IL243248A0 (en) Purification method
HRP20150761T1 (hr) Postupak za proäśišä†avanje lipopeptida
EP2634142A4 (en) PROCESS FOR THE PURIFICATION OF CHLOROSILANES
IL215234A0 (en) Method for purifying recombinant fsh
EP2471740A4 (en) PROCESS FOR THE PURIFICATION OF CHLOROSILANE
EP2267151A4 (en) METHOD FOR TITRATION OF VIRUSES
GB0808908D0 (en) Purification process
ZA201302330B (en) Method for purifying water
EP2743259A4 (en) PROCESS FOR CLEANING (S) -OXIRACETAM
IL209654A0 (en) Method for purifying erythropoietin
IL238819A (en) Methods to produce viruses
PL2397214T3 (pl) Sposób oczyszczania dymów ze spalania
EP2465819A4 (en) PROCESS FOR THE PURIFICATION OF CHLOROSILANES
GB0818228D0 (en) Purification process
PL2465598T3 (pl) Sposób oczyszczania gazów spalinowych
EP2522741A4 (en) genotyping
GB0811505D0 (en) Purification process
HK1164935A1 (en) Method for purifying the rabies virus