ATE316572T1 - Attenuierte rekombinante stabile tollwutvirusmutanten und lebendimpfstoffe - Google Patents
Attenuierte rekombinante stabile tollwutvirusmutanten und lebendimpfstoffeInfo
- Publication number
- ATE316572T1 ATE316572T1 AT02076485T AT02076485T ATE316572T1 AT E316572 T1 ATE316572 T1 AT E316572T1 AT 02076485 T AT02076485 T AT 02076485T AT 02076485 T AT02076485 T AT 02076485T AT E316572 T1 ATE316572 T1 AT E316572T1
- Authority
- AT
- Austria
- Prior art keywords
- rabies virus
- live vaccines
- attenuated recombinant
- virus mutants
- recombinant stable
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N7/00—Viruses; Bacteriophages; Compositions thereof; Preparation or purification thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/12—Viral antigens
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/12—Viral antigens
- A61K39/205—Rhabdoviridae, e.g. rabies virus
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/04—Immunostimulants
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
- A61K2039/525—Virus
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
- A61K2039/525—Virus
- A61K2039/5254—Virus avirulent or attenuated
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/54—Medicinal preparations containing antigens or antibodies characterised by the route of administration
- A61K2039/541—Mucosal route
- A61K2039/542—Mucosal route oral/gastrointestinal
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2760/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses negative-sense
- C12N2760/00011—Details
- C12N2760/20011—Rhabdoviridae
- C12N2760/20111—Lyssavirus, e.g. rabies virus
- C12N2760/20122—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2760/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses negative-sense
- C12N2760/00011—Details
- C12N2760/20011—Rhabdoviridae
- C12N2760/20111—Lyssavirus, e.g. rabies virus
- C12N2760/20134—Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2760/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses negative-sense
- C12N2760/00011—Details
- C12N2760/20011—Rhabdoviridae
- C12N2760/20111—Lyssavirus, e.g. rabies virus
- C12N2760/20161—Methods of inactivation or attenuation
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Virology (AREA)
- Medicinal Chemistry (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Immunology (AREA)
- Pharmacology & Pharmacy (AREA)
- Genetics & Genomics (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Microbiology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Epidemiology (AREA)
- Mycology (AREA)
- Zoology (AREA)
- Biochemistry (AREA)
- Wood Science & Technology (AREA)
- Molecular Biology (AREA)
- Biomedical Technology (AREA)
- Biophysics (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Tropical Medicine & Parasitology (AREA)
- Gastroenterology & Hepatology (AREA)
- General Engineering & Computer Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Biotechnology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Communicable Diseases (AREA)
- Oncology (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
EP01201464 | 2001-04-23 | ||
EP01203773 | 2001-10-05 |
Publications (1)
Publication Number | Publication Date |
---|---|
ATE316572T1 true ATE316572T1 (de) | 2006-02-15 |
Family
ID=26076884
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
AT02076485T ATE316572T1 (de) | 2001-04-23 | 2002-04-17 | Attenuierte rekombinante stabile tollwutvirusmutanten und lebendimpfstoffe |
Country Status (10)
Country | Link |
---|---|
US (1) | US6887479B2 (de) |
EP (1) | EP1253197B1 (de) |
AR (1) | AR033873A1 (de) |
AT (1) | ATE316572T1 (de) |
BR (1) | BR0201366A (de) |
CA (1) | CA2382993A1 (de) |
DE (1) | DE60208854T2 (de) |
ES (1) | ES2257505T3 (de) |
PT (1) | PT1253197E (de) |
TR (1) | TR200201081A3 (de) |
Families Citing this family (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP1768697B1 (de) * | 2004-07-12 | 2010-06-02 | Thomas Jefferson University | Zusammensetzungen mit rekombinantem tollwutvirus |
BRPI0617373B1 (pt) | 2005-10-14 | 2022-04-05 | The Goverment of The United States of America, Representado por, The Secretary of The Department of Health and Human Services, Centers for Disease Control and Prevention | Composições e métodos do vírus da raiva |
US20100278864A1 (en) * | 2005-12-14 | 2010-11-04 | University Of Georgia Research Foundation, Inc. | Rabies Vaccine |
FR2944292B1 (fr) | 2009-04-08 | 2013-08-23 | Sanofi Pasteur | Procede de purification du virus rabique |
RU2013102929A (ru) | 2010-06-24 | 2014-07-27 | Зе Гавермент Оф Зе Юнайтед Стейтс Оф Америка Эз Репрезентед Бай Зе Секретари Оф Зе Департмент Оф Хэлс Энд Хьюман Сервисез, Сентерз Фо Дизиз Контрол Энд Привеншн | Пан-лиссавирусные вакцины против бешенства |
WO2012106490A1 (en) | 2011-02-03 | 2012-08-09 | The Government Of The U.S.A., As Represented By The Secretary, Department Of Health & Human Services | Multivalent vaccines for rabies virus and filoviruses |
US11041170B2 (en) | 2016-04-04 | 2021-06-22 | Thomas Jefferson University | Multivalent vaccines for rabies virus and coronaviruses |
Family Cites Families (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
IL143149A0 (en) * | 1998-11-27 | 2002-04-21 | Akzo Nobel Nv | Stable, attenuated rabies virus mutants and live vaccines thereof |
-
2002
- 2002-04-17 EP EP02076485A patent/EP1253197B1/de not_active Expired - Lifetime
- 2002-04-17 PT PT02076485T patent/PT1253197E/pt unknown
- 2002-04-17 ES ES02076485T patent/ES2257505T3/es not_active Expired - Lifetime
- 2002-04-17 DE DE60208854T patent/DE60208854T2/de not_active Expired - Lifetime
- 2002-04-17 AT AT02076485T patent/ATE316572T1/de not_active IP Right Cessation
- 2002-04-19 TR TR2002/01081A patent/TR200201081A3/tr unknown
- 2002-04-22 CA CA002382993A patent/CA2382993A1/en active Pending
- 2002-04-22 BR BR0201366-5A patent/BR0201366A/pt not_active Application Discontinuation
- 2002-04-23 US US10/128,628 patent/US6887479B2/en not_active Expired - Fee Related
- 2002-04-23 AR ARP020101463A patent/AR033873A1/es not_active Application Discontinuation
Also Published As
Publication number | Publication date |
---|---|
CA2382993A1 (en) | 2002-10-23 |
EP1253197A1 (de) | 2002-10-30 |
PT1253197E (pt) | 2006-06-30 |
EP1253197B1 (de) | 2006-01-25 |
AR033873A1 (es) | 2004-01-07 |
ES2257505T3 (es) | 2006-08-01 |
DE60208854T2 (de) | 2006-08-17 |
DE60208854D1 (de) | 2006-04-13 |
TR200201081A2 (tr) | 2002-11-21 |
US6887479B2 (en) | 2005-05-03 |
TR200201081A3 (tr) | 2002-11-21 |
BR0201366A (pt) | 2003-06-10 |
US20020164356A1 (en) | 2002-11-07 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
UEP | Publication of translation of european patent specification |
Ref document number: 1253197 Country of ref document: EP |
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REN | Ceased due to non-payment of the annual fee |