PT2379734T - Método para o controlo da massa molecular do polissacárido do serotipo 19a de streptococcus pneumoniae - Google Patents

Método para o controlo da massa molecular do polissacárido do serotipo 19a de streptococcus pneumoniae

Info

Publication number
PT2379734T
PT2379734T PT97958623T PT09795862T PT2379734T PT 2379734 T PT2379734 T PT 2379734T PT 97958623 T PT97958623 T PT 97958623T PT 09795862 T PT09795862 T PT 09795862T PT 2379734 T PT2379734 T PT 2379734T
Authority
PT
Portugal
Prior art keywords
molecular weight
streptococcus pneumoniae
pneumoniae serotype
polysaccharide molecular
controlling
Prior art date
Application number
PT97958623T
Other languages
English (en)
Inventor
Heather Crinean Jean
Original Assignee
Wyeth Llc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Wyeth Llc filed Critical Wyeth Llc
Publication of PT2379734T publication Critical patent/PT2379734T/pt

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/20Bacteria; Culture media therefor
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P19/00Preparation of compounds containing saccharide radicals
    • C12P19/04Polysaccharides, i.e. compounds containing more than five saccharide radicals attached to each other by glycosidic bonds
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/02Immunomodulators
    • A61P37/04Immunostimulants

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • Immunology (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Virology (AREA)
  • Biomedical Technology (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Polysaccharides And Polysaccharide Derivatives (AREA)
PT97958623T 2008-12-18 2009-12-17 Método para o controlo da massa molecular do polissacárido do serotipo 19a de streptococcus pneumoniae PT2379734T (pt)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US13856308P 2008-12-18 2008-12-18

Publications (1)

Publication Number Publication Date
PT2379734T true PT2379734T (pt) 2018-04-27

Family

ID=42266457

Family Applications (1)

Application Number Title Priority Date Filing Date
PT97958623T PT2379734T (pt) 2008-12-18 2009-12-17 Método para o controlo da massa molecular do polissacárido do serotipo 19a de streptococcus pneumoniae

Country Status (19)

Country Link
US (1) US8795689B2 (pt)
EP (1) EP2379734B1 (pt)
JP (1) JP5843612B2 (pt)
KR (2) KR101593770B1 (pt)
CN (1) CN102257155B (pt)
AU (1) AU2009335826B2 (pt)
BR (1) BRPI0922981A8 (pt)
CA (1) CA2743710C (pt)
DK (1) DK2379734T3 (pt)
ES (1) ES2666698T3 (pt)
HK (1) HK1163750A1 (pt)
HU (1) HUE037465T2 (pt)
IL (1) IL213169A (pt)
MX (1) MX2011006432A (pt)
PL (1) PL2379734T3 (pt)
PT (1) PT2379734T (pt)
RU (1) RU2511404C2 (pt)
SI (1) SI2379734T1 (pt)
WO (1) WO2010080486A2 (pt)

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* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
PL2385981T3 (pl) * 2008-12-18 2020-01-31 Wyeth Llc Sposób kontroli masy cząsteczkowej polisacharydów streptococcus pneumoniae z zastosowaniem węgla
KR101450958B1 (ko) 2009-04-30 2014-10-15 콜레이 파마시티컬 그룹, 인코포레이티드 폐렴구균 백신 및 그의 용도
WO2013088448A1 (en) * 2011-12-15 2013-06-20 Serum Institute Of India Ltd. A novel process of cultivating bacteria for yield improvement of capsular polyoses
CA2884241C (en) * 2012-09-07 2018-11-20 Sk Chemicals Co., Ltd. Production method for capsular polysaccharide having pneumococcal serotype
US11951165B2 (en) 2016-12-30 2024-04-09 Vaxcyte, Inc. Conjugated vaccine carrier proteins
CN116870144A (zh) 2017-01-31 2023-10-13 默沙东有限责任公司 制备多糖-蛋白缀合物的方法
CN110337307A (zh) 2017-02-24 2019-10-15 默沙东公司 增强肺炎链球菌多糖-蛋白缀合物的免疫原性
US10729763B2 (en) 2017-06-10 2020-08-04 Inventprise, Llc Mixtures of polysaccharide-protein pegylated compounds
CA3066911C (en) 2017-06-10 2022-05-24 Inventprise, Llc Multivalent conjugate vaccines with bivalent or multivalent conjugate polysaccharides that provide improved immunogenicity and avidity
BR112020004471A8 (pt) 2017-09-07 2022-11-01 Merck Sharp & Dohme Polissacarídeos pneumocócicos e uso dos mesmos em conjugados imunogênicos polissacarídeo-proteína carreadora
CN111065387B (zh) 2017-09-07 2023-08-25 默沙东有限责任公司 肺炎球菌多糖及其在免疫原性多糖-载体蛋白缀合物中的用途
NZ765694A (en) 2017-12-06 2024-03-22 Merck Sharp & Dohme Llc Compositions comprising streptococcus pneumoniae polysaccharide-protein conjugates and methods of use thereof
JP2021522213A (ja) * 2018-04-18 2021-08-30 エスケー バイオサイエンス カンパニー リミテッド ストレプトコッカス・ニューモニエ莢膜多糖類及びその免疫原性接合体
US11896656B2 (en) 2018-04-30 2024-02-13 Merck Sharp & Dohme Llc Methods for providing a homogenous solution of lyophilized mutant diptheria toxin in dimethylsulfoxide
US20220296695A1 (en) 2018-12-19 2022-09-22 Merck Sharp & Dohme Corp. Compositions comprising streptococcus pneumoniae polysaccharide-protein conjugates and methods of use thereof

Family Cites Families (25)

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Publication number Priority date Publication date Assignee Title
CA1115210A (en) 1977-11-28 1981-12-29 Dennis J. Carlo Pneumococcal vaccine
US4221906A (en) * 1979-03-19 1980-09-09 American Cyanamid Company Stabilization of pneumococcal polysaccharides
US4242501A (en) 1979-08-08 1980-12-30 American Cyanamid Company Purification of pneumococcal capsular polysaccharides
FR2495939B1 (fr) 1980-12-11 1985-10-11 Merieux Inst Procede de purification de polyosides de streptococcus pneumoniae et vaccin a base de polyosides ainsi purifies
BE889979A (fr) 1981-08-14 1982-02-15 Smith Kline Rit Procede de preparation de polysaccharides bacteriens capsulaires antigeniques purifies, produits obtenus et leur utilisation
US4686102A (en) * 1984-04-12 1987-08-11 American Cyanamid Company Multivalent pneumococcal vaccine and preparation thereof
CA2059692C (en) * 1991-01-28 2004-11-16 Peter J. Kniskern Pneumoccoccal polysaccharide conjugate vaccine
CA2059693C (en) * 1991-01-28 2003-08-19 Peter J. Kniskern Polysaccharide antigens from streptococcus pneumoniae
US5314822A (en) * 1992-10-15 1994-05-24 Merck & Co., Inc. Method of clonal growth of Streptococcus pneumoniae
US5714354A (en) * 1995-06-06 1998-02-03 American Home Products Corporation Alcohol-free pneumococcal polysaccharide purification process
US6146902A (en) * 1998-12-29 2000-11-14 Aventis Pasteur, Inc. Purification of polysaccharide-protein conjugate vaccines by ultrafiltration with ammonium sulfate solutions
NZ521343A (en) * 2000-03-16 2005-03-24 Philadelphia Children Hospital Modulating production of pneumococcal capsular polysaccharide
US6743610B2 (en) * 2001-03-30 2004-06-01 The University Of Chicago Method to produce succinic acid from raw hydrolysates
ITTS20010013A1 (it) 2001-06-04 2002-12-04 Ct Ricerche Poly Tec H A R L S Nuovi derivati di ialuronano.
PT1664319E (pt) * 2003-09-11 2010-06-17 Staat Der Nederlanden Vert Doo Processo para a produção de um polissacarídeo capsular para ser usado em vacinas de conjugados
ES2382048T3 (es) * 2005-04-08 2012-06-04 Wyeth Llc Composición conjugada de proteína-polisacárido neumococico multivante
CA2604362C (en) 2005-04-08 2013-11-12 Wyeth Separation of contaminants from streptococcus pneumoniae polysaccharide by ph manipulation
US7709001B2 (en) * 2005-04-08 2010-05-04 Wyeth Llc Multivalent pneumococcal polysaccharide-protein conjugate composition
US7955605B2 (en) * 2005-04-08 2011-06-07 Wyeth Llc Multivalent pneumococcal polysaccharide-protein conjugate composition
US20070184072A1 (en) * 2005-04-08 2007-08-09 Wyeth Multivalent pneumococcal polysaccharide-protein conjugate composition
GB0522303D0 (en) * 2005-11-01 2005-12-07 Chiron Srl Culture method
RU2460539C2 (ru) 2006-10-10 2012-09-10 Вайет СПОСОБ ОЧИСТКИ ПОЛИСАХАРИДОВ Streptococcus pneumoniae 3 ТИПА (ВАРИАНТЫ)
US7860500B2 (en) * 2006-10-27 2010-12-28 Motorola, Inc. Method and apparatus for determining appropriate channels for communication
HUE031567T2 (hu) * 2007-03-23 2017-07-28 Wyeth Llc Rövidített tisztítási eljárás Streptococcus pneumoniae tok-poliszacharidok elõállítására
PL2385981T3 (pl) * 2008-12-18 2020-01-31 Wyeth Llc Sposób kontroli masy cząsteczkowej polisacharydów streptococcus pneumoniae z zastosowaniem węgla

Also Published As

Publication number Publication date
KR20130136011A (ko) 2013-12-11
WO2010080486A3 (en) 2010-11-04
AU2009335826A1 (en) 2010-07-15
ES2666698T3 (es) 2018-05-07
MX2011006432A (es) 2011-09-29
CA2743710C (en) 2017-01-24
BRPI0922981A8 (pt) 2019-11-26
DK2379734T3 (en) 2018-04-23
KR101593770B1 (ko) 2016-02-15
US20100158953A1 (en) 2010-06-24
AU2009335826B2 (en) 2013-10-31
HK1163750A1 (zh) 2012-09-14
US8795689B2 (en) 2014-08-05
CA2743710A1 (en) 2010-07-15
JP2012512660A (ja) 2012-06-07
RU2011128564A (ru) 2013-01-27
EP2379734A2 (en) 2011-10-26
EP2379734B1 (en) 2018-03-21
KR20110091546A (ko) 2011-08-11
IL213169A0 (en) 2011-07-31
CN102257155B (zh) 2016-03-02
BRPI0922981A2 (pt) 2015-08-25
JP5843612B2 (ja) 2016-01-13
PL2379734T3 (pl) 2018-08-31
CN102257155A (zh) 2011-11-23
RU2511404C2 (ru) 2014-04-10
SI2379734T1 (en) 2018-05-31
HUE037465T2 (hu) 2018-09-28
IL213169A (en) 2015-02-26
WO2010080486A2 (en) 2010-07-15

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