PT2346841E - Ácidos 2-aril-propiónicos e derivados e composições farmacêuticas contendo-os - Google Patents
Ácidos 2-aril-propiónicos e derivados e composições farmacêuticas contendo-os Download PDFInfo
- Publication number
- PT2346841E PT2346841E PT97831671T PT09783167T PT2346841E PT 2346841 E PT2346841 E PT 2346841E PT 97831671 T PT97831671 T PT 97831671T PT 09783167 T PT09783167 T PT 09783167T PT 2346841 E PT2346841 E PT 2346841E
- Authority
- PT
- Portugal
- Prior art keywords
- aryl
- derivatives
- pharmaceutical compositions
- compositions containing
- propionic acids
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D263/00—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings
- C07D263/02—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings
- C07D263/30—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D263/34—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D263/48—Nitrogen atoms not forming part of a nitro radical
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/12—Drugs for disorders of the urinary system of the kidneys
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
- C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
- C07D277/20—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D277/32—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D277/38—Nitrogen atoms
- C07D277/42—Amino or imino radicals substituted by hydrocarbon or substituted hydrocarbon radicals
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Immunology (AREA)
- Rheumatology (AREA)
- Urology & Nephrology (AREA)
- Vascular Medicine (AREA)
- Heart & Thoracic Surgery (AREA)
- Transplantation (AREA)
- Pain & Pain Management (AREA)
- Cardiology (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Physical Education & Sports Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Thiazole And Isothizaole Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP08164605A EP2166006A1 (en) | 2008-09-18 | 2008-09-18 | 2-aryl-propionic acids and derivatives and pharmaceutical compositions containing them |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| PT2346841E true PT2346841E (pt) | 2015-05-07 |
Family
ID=40291117
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PT97831671T PT2346841E (pt) | 2008-09-18 | 2009-09-18 | Ácidos 2-aril-propiónicos e derivados e composições farmacêuticas contendo-os |
Country Status (18)
| Country | Link |
|---|---|
| US (1) | US8624036B2 (pt) |
| EP (2) | EP2166006A1 (pt) |
| JP (1) | JP5571669B2 (pt) |
| CN (1) | CN102159558B (pt) |
| AU (1) | AU2009294558B2 (pt) |
| BR (1) | BRPI0918759A2 (pt) |
| CA (1) | CA2737099C (pt) |
| CY (1) | CY1116176T1 (pt) |
| DK (1) | DK2346841T3 (pt) |
| ES (1) | ES2534634T3 (pt) |
| HR (1) | HRP20150395T1 (pt) |
| IL (1) | IL211683A (pt) |
| PL (1) | PL2346841T3 (pt) |
| PT (1) | PT2346841E (pt) |
| RU (1) | RU2520212C2 (pt) |
| SI (1) | SI2346841T1 (pt) |
| SM (1) | SMT201500098B (pt) |
| WO (1) | WO2010031835A2 (pt) |
Families Citing this family (22)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20130231340A1 (en) | 2012-03-02 | 2013-09-05 | Sareum Limited | Pharmaceutical compounds |
| US10561676B2 (en) * | 2013-08-02 | 2020-02-18 | Syntrix Biosystems Inc. | Method for treating cancer using dual antagonists of CXCR1 and CXCR2 |
| US10046002B2 (en) | 2013-08-02 | 2018-08-14 | Syntrix Biosystems Inc. | Method for treating cancer using chemokine antagonists |
| AU2013399913B2 (en) * | 2013-09-03 | 2018-03-15 | Sareum Limited | Pharmaceutical compounds |
| AR103399A1 (es) * | 2015-01-15 | 2017-05-10 | Actelion Pharmaceuticals Ltd | Derivados de (r)-2-metil-piperazina como moduladores del receptor cxcr3 |
| EP3117835A1 (en) * | 2015-07-14 | 2017-01-18 | Dompé farmaceutici s.p.a. | Il-8 inhibitors for use in the treatment of certain urological disorders |
| HUE056606T2 (hu) * | 2016-01-15 | 2022-02-28 | Dompe Farm Spa | IL-8 inhibitorok kemoterápia által indukált perifériás neuropathia kezelésében történõ alkalmazásra |
| EP3192504A1 (en) | 2016-01-15 | 2017-07-19 | Dompé farmaceutici S.p.A. | Il-8 inhibitors for use in the treatment of chemotherapy-induced peripheral neuropathy |
| WO2018067548A1 (en) | 2016-10-03 | 2018-04-12 | The Children's Medicial Center Corporation | Prevention and treatment of diabetic nephropathy |
| GB201617871D0 (en) | 2016-10-21 | 2016-12-07 | Sareum Limited | Pharmaceutical compounds |
| US10660909B2 (en) | 2016-11-17 | 2020-05-26 | Syntrix Biosystems Inc. | Method for treating cancer using chemokine antagonists |
| EP3342407A1 (en) * | 2017-01-03 | 2018-07-04 | Dompé farmaceutici S.p.A. | Il-8 inihibitors for use in the treatment of some urological disorders |
| EP3409277A1 (en) * | 2017-05-30 | 2018-12-05 | Dompé farmaceutici s.p.a. | Il-8 inhibitors for use in the treatment and/or prevention of bacterial secondary infections |
| EP3476390A1 (en) | 2017-10-24 | 2019-05-01 | Dompé farmaceutici S.p.A. | Il-8 inhibitors for use in the treatment of sarcomas |
| WO2019165315A1 (en) | 2018-02-23 | 2019-08-29 | Syntrix Biosystems Inc. | Method for treating cancer using chemokine antagonists alone or in combination |
| EP3868369A1 (en) | 2020-02-21 | 2021-08-25 | Dompe' Farmaceutici S.P.A. | Cxcl8 inhibitor and pharmaceutical composition thereof for use in the treatment of cancer-related fatigue |
| EP3868368A1 (en) | 2020-02-21 | 2021-08-25 | Dompe' Farmaceutici S.P.A. | Cxcl8 (interleukin-8) activity inhibitor and corticosteroid combination and pharmaceutical composition and use thereof |
| EP4008325A1 (en) | 2020-12-02 | 2022-06-08 | Dompe' Farmaceutici S.P.A. | Cxcl8 inhibitors for use in the treatment of covid-19 |
| IL296751A (en) | 2020-03-26 | 2022-11-01 | Dompe Farm Spa | cxcl8 inhibitors for use in the treatment of covid-19 |
| EP3884932A1 (en) | 2020-03-26 | 2021-09-29 | Dompe' Farmaceutici S.P.A. | Cxcl8 inhibitors for use in the treatment of covid-19 |
| WO2022098822A1 (en) | 2020-11-05 | 2022-05-12 | Icahn School Of Medicine At Mount Sinai | Cxcr1/cxcr2 inhibitors for use in treating myelofibrosis |
| EP4052702A1 (en) | 2021-03-04 | 2022-09-07 | Dompé farmaceutici S.p.a. | Cxcl8 inhibitor and pharmaceutical composition thereof for use in the treatment of seizures |
Family Cites Families (15)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS565747B2 (pt) * | 1973-10-24 | 1981-02-06 | ||
| CA1051906A (en) * | 1973-10-24 | 1979-04-03 | Shionogi And Co. | Thiazole derivatives and production thereof |
| JPS5537556B2 (pt) * | 1973-12-27 | 1980-09-29 | ||
| US4025528A (en) * | 1973-10-24 | 1977-05-24 | Shionogi & Co., Ltd. | Thiazole derivatives of benzoic and phenylalkanoic acids |
| JPS5629871B2 (pt) * | 1974-05-22 | 1981-07-10 | ||
| JPS62142168A (ja) * | 1985-10-16 | 1987-06-25 | Mitsubishi Chem Ind Ltd | チアゾ−ル誘導体及びそれを有効成分とするロイコトリエンきつ抗剤 |
| IT1298214B1 (it) | 1998-01-28 | 1999-12-20 | Dompe Spa | Sali dell'acido (r) 2-(3-benzoilfenil) propionico e loro composizioni farmaceutiche. |
| IT1303249B1 (it) | 1998-10-23 | 2000-11-06 | Dompe Spa | Alcune n-(2-aril-propionil)-solfonammidi e preparazionifarmaceutiche che le contengono. |
| IT1317826B1 (it) | 2000-02-11 | 2003-07-15 | Dompe Spa | Ammidi, utili nell'inibizione della chemiotassi dei neutrofiliindotta da il-8. |
| ITMI20012434A1 (it) | 2001-11-20 | 2003-05-20 | Dompe Spa | Acidi 2-aril-propionici e composizioni farmaceutiche che li contengono |
| CA2474322A1 (en) * | 2002-01-25 | 2003-07-31 | Kylix Pharmaceuticals B.V. | 4(hetero-) aryl substituted (thia-/oxa-/pyra) zoles for inhibition of tie-2 |
| EP1776336B1 (en) * | 2004-03-23 | 2009-09-30 | DOMPE' pha.r.ma s.p.a. | 2-phenylpropionic acid derivatives and pharmaceutical compositions containing them |
| CN101448784B (zh) * | 2006-05-18 | 2012-07-04 | 冬姆佩股份公司 | (2r)-2-[(4-磺酰基)氨基苯基]丙酰胺及含有它们的药物组合物 |
| WO2008075184A2 (en) * | 2006-12-19 | 2008-06-26 | Dompe' Pha.R.Ma S.P.A. | 2-aryl-2-fluoropropanoic acids and derivatives and pharmaceutical compositions containing them |
| JP5374511B2 (ja) * | 2007-10-18 | 2013-12-25 | ドムペ・ソチエタ・ペル・アツィオーニ | （ｒ）−４−（ヘテロアリール）フェニルエチル誘導体及びそれらを含有する医薬組成物 |
-
2008
- 2008-09-18 EP EP08164605A patent/EP2166006A1/en not_active Withdrawn
-
2009
- 2009-09-18 JP JP2011527334A patent/JP5571669B2/ja active Active
- 2009-09-18 DK DK09783167.1T patent/DK2346841T3/en active
- 2009-09-18 CA CA2737099A patent/CA2737099C/en active Active
- 2009-09-18 BR BRPI0918759A patent/BRPI0918759A2/pt not_active Application Discontinuation
- 2009-09-18 ES ES09783167.1T patent/ES2534634T3/es active Active
- 2009-09-18 EP EP09783167.1A patent/EP2346841B1/en active Active
- 2009-09-18 PL PL09783167T patent/PL2346841T3/pl unknown
- 2009-09-18 US US13/063,105 patent/US8624036B2/en active Active
- 2009-09-18 SI SI200931170T patent/SI2346841T1/sl unknown
- 2009-09-18 PT PT97831671T patent/PT2346841E/pt unknown
- 2009-09-18 CN CN200980136860.5A patent/CN102159558B/zh active Active
- 2009-09-18 WO PCT/EP2009/062109 patent/WO2010031835A2/en active Application Filing
- 2009-09-18 AU AU2009294558A patent/AU2009294558B2/en active Active
- 2009-09-18 RU RU2011114992/04A patent/RU2520212C2/ru active
-
2011
- 2011-03-10 IL IL211683A patent/IL211683A/en active IP Right Grant
-
2015
- 2015-04-08 CY CY20151100336T patent/CY1116176T1/el unknown
- 2015-04-09 HR HRP20150395TT patent/HRP20150395T1/hr unknown
- 2015-04-22 SM SM201500098T patent/SMT201500098B/xx unknown
Also Published As
| Publication number | Publication date |
|---|---|
| US20110207785A1 (en) | 2011-08-25 |
| CY1116176T1 (el) | 2017-02-08 |
| EP2166006A1 (en) | 2010-03-24 |
| SMT201500098B (it) | 2015-07-09 |
| DK2346841T3 (en) | 2015-04-20 |
| JP5571669B2 (ja) | 2014-08-13 |
| US8624036B2 (en) | 2014-01-07 |
| BRPI0918759A2 (pt) | 2015-12-29 |
| IL211683A0 (en) | 2011-06-30 |
| CN102159558B (zh) | 2015-01-07 |
| WO2010031835A2 (en) | 2010-03-25 |
| EP2346841B1 (en) | 2015-01-14 |
| IL211683A (en) | 2014-01-30 |
| JP2012502957A (ja) | 2012-02-02 |
| RU2520212C2 (ru) | 2014-06-20 |
| RU2011114992A (ru) | 2012-10-27 |
| CN102159558A (zh) | 2011-08-17 |
| HRP20150395T1 (hr) | 2015-06-19 |
| WO2010031835A3 (en) | 2010-06-24 |
| ES2534634T3 (es) | 2015-04-27 |
| PL2346841T3 (pl) | 2015-07-31 |
| CA2737099A1 (en) | 2010-03-25 |
| SI2346841T1 (sl) | 2015-07-31 |
| EP2346841A2 (en) | 2011-07-27 |
| AU2009294558B2 (en) | 2014-12-18 |
| AU2009294558A1 (en) | 2010-03-25 |
| CA2737099C (en) | 2016-07-05 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| IL211683A0 (en) | 2-aryl-propionic acids and derivatives and pharmaceutical compositions containing them | |
| HUS1800043I1 (hu) | 514 számú gyógyszerkészítmény | |
| IL217912A (en) | History of 5-Amino-1-Benzimidazole-Pyrazole and Pharmaceutical Preparations Containing It | |
| EP2360188A4 (en) | HYALURONIC ACID DERIVATIVE AND PHARMACEUTICAL COMPOSITION THEREOF | |
| IL199853A (en) | Converged history of 5-Hydroxy-Admentil-2-Reindeer and Pharmaceutical Preparation containing them | |
| IL206594A (en) | The history of azinone-tetrahydropyridoindole and its containing pharmaceutical preparations | |
| IL215497A0 (en) | Oxadiazile derivatives and pharmaceutical compositions containing them | |
| IL210446A (en) | History of fibrin and medicinal preparations containing them | |
| EP2277861A4 (en) | CYCLIC AMIN-1-CARBOXYLIC ACID EST DERIVATIVE AND PHARMACEUTICAL COMPOSITION THEREWITH | |
| SI2320739T1 (sl) | Farmacevtski sestavki in postopki za njihovo stabiliziranje | |
| IL216462A (en) | Pharmaceuticals containing nitrile history and uses | |
| EP2322505A4 (en) | 1-ADAMANTYLAZETIDIN-2-ON DERIVATIVE, PREPARATION THEREOF AND PHARMACEUTICAL PREPARATION THEREWITH | |
| EP2279999A4 (en) | RETINOID DERIVATIVE AND PHARMACEUTICAL COMPOSITION AND USE THEREOF | |
| HK1145837A1 (en) | Amide derivative and pharmaceutical composition containing the same | |
| HK1209022A1 (en) | Amino acid derivatives used as pharmaceutical substances | |
| PL2484661T3 (pl) | Pochodna 2,3-dihydro-1h-inden-2-ylomocznika i jej zastosowanie farmaceutyczne | |
| EP2263671A4 (en) | PHARMACEUTICAL COMPOSITION CONTAINING AN AMIDE DERIVATIVE | |
| ZA201005316B (en) | 2-amino-2-phenyl-alkanol derivatives, their preparation and pharmaceutical compositions containing them | |
| ZA201200165B (en) | 2-amino-2phenyl-alkanol derivatives, preparation thereof, and pharmaceutical compositions containing same | |
| TWI365071B (en) | Isoxazole derivatives and pharmaceutical compositions comprising the same | |
| AU2008903115A0 (en) | Pharmaceutical Formulation |