PT2314609T - Derivado de metastina e sua utilização - Google Patents

Derivado de metastina e sua utilização

Info

Publication number
PT2314609T
PT2314609T PT98030042T PT09803004T PT2314609T PT 2314609 T PT2314609 T PT 2314609T PT 98030042 T PT98030042 T PT 98030042T PT 09803004 T PT09803004 T PT 09803004T PT 2314609 T PT2314609 T PT 2314609T
Authority
PT
Portugal
Prior art keywords
metastin derivative
metastin
derivative
Prior art date
Application number
PT98030042T
Other languages
English (en)
Inventor
Asami Taiji
Original Assignee
Takeda Pharmaceuticals Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Takeda Pharmaceuticals Co filed Critical Takeda Pharmaceuticals Co
Publication of PT2314609T publication Critical patent/PT2314609T/pt

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575Hormones
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/51Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
    • A61K47/56Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule
    • A61K47/59Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyureas or polyurethanes
    • A61K47/60Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyureas or polyurethanes the organic macromolecular compound being a polyoxyalkylene oligomer, polymer or dendrimer, e.g. PEG, PPG, PEO or polyglycerol
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00Drugs for genital or sexual disorders; Contraceptives
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00Drugs for genital or sexual disorders; Contraceptives
    • A61P15/06Antiabortive agents; Labour repressants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00Drugs for genital or sexual disorders; Contraceptives
    • A61P15/08Drugs for genital or sexual disorders; Contraceptives for gonadal disorders or for enhancing fertility, e.g. inducers of ovulation or of spermatogenesis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/28Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/06Antihyperlipidemics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/08Drugs for disorders of the metabolism for glucose homeostasis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/08Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • A61P35/04Antineoplastic agents specific for metastasis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00Drugs for disorders of the endocrine system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00Drugs for disorders of the endocrine system
    • A61P5/24Drugs for disorders of the endocrine system of the sex hormones

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Endocrinology (AREA)
  • Diabetes (AREA)
  • Obesity (AREA)
  • Hematology (AREA)
  • Reproductive Health (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Gynecology & Obstetrics (AREA)
  • Pregnancy & Childbirth (AREA)
  • Molecular Biology (AREA)
  • Epidemiology (AREA)
  • Toxicology (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Emergency Medicine (AREA)
  • Genetics & Genomics (AREA)
  • Hospice & Palliative Care (AREA)
  • Oncology (AREA)
  • Psychiatry (AREA)
  • Dermatology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
PT98030042T 2008-07-30 2009-07-29 Derivado de metastina e sua utilização PT2314609T (pt)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP2008196598 2008-07-30

Publications (1)

Publication Number Publication Date
PT2314609T true PT2314609T (pt) 2017-03-06

Family

ID=41610461

Family Applications (1)

Application Number Title Priority Date Filing Date
PT98030042T PT2314609T (pt) 2008-07-30 2009-07-29 Derivado de metastina e sua utilização

Country Status (13)

Country Link
US (1) US20110212890A1 (pt)
EP (2) EP2314609B1 (pt)
JP (1) JP5698977B2 (pt)
CY (1) CY1118975T1 (pt)
DK (1) DK2314609T3 (pt)
ES (1) ES2617657T3 (pt)
HR (1) HRP20170319T1 (pt)
HU (1) HUE030900T2 (pt)
LT (1) LT2314609T (pt)
PL (1) PL2314609T3 (pt)
PT (1) PT2314609T (pt)
SI (1) SI2314609T1 (pt)
WO (1) WO2010013762A1 (pt)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8592379B2 (en) * 2008-04-30 2013-11-26 Kyoto University Metastin derivative and use thereof
JP5455661B2 (ja) 2009-01-29 2014-03-26 ギガフォトン株式会社 極端紫外光源装置
US9127038B2 (en) 2011-08-04 2015-09-08 Merck Sharp & Dohme Corp. Kisspeptide-pentasaccharide conjugates
TWI778979B (zh) 2016-09-30 2022-10-01 瑞士商麥歐文科學有限公司 治療女性不孕症之方法

Family Cites Families (28)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IE50892B1 (en) 1980-02-11 1986-08-06 Novo Industri As Process for preparing insulin esters
US5824784A (en) * 1994-10-12 1998-10-20 Amgen Inc. N-terminally chemically modified protein compositions and methods
JP4486187B2 (ja) 1998-10-27 2010-06-23 武田薬品工業株式会社 新規g蛋白質共役型レセプター蛋白質、そのdnaおよびそのリガンド
US6638906B1 (en) * 1999-12-13 2003-10-28 Nobex Corporation Amphiphilic polymers and polypeptide conjugates comprising same
CA2394404A1 (en) * 1999-12-17 2001-06-21 Takeda Chemical Industries, Ltd. Process for producing kiss-1 peptide
US20050240008A1 (en) * 2000-03-30 2005-10-27 Tetsuya Ohtaki Novel protein, dna thereof and process for producing the same
WO2002085399A1 (en) 2001-04-20 2002-10-31 Takeda Chemical Industries, Ltd. Peptide-containing preparations
US7112662B2 (en) * 2001-09-19 2006-09-26 Takeda Pharmaceutical Company Limited Anti-metasin antibodies and their methods of use
US20050176091A1 (en) * 2002-01-11 2005-08-11 Takao Yamada Process for producing kiss-1 peptide
US20060035875A1 (en) * 2002-10-09 2006-02-16 Yukimasa Shiotsu Remedy for hormone-dependent cancer
JP4804714B2 (ja) * 2002-12-26 2011-11-02 武田薬品工業株式会社 メタスチン誘導体およびその用途
EP1577323B1 (en) * 2002-12-26 2013-07-10 Takeda Pharmaceutical Company Limited Metastin derivative and use thereof
US6800611B2 (en) 2003-01-06 2004-10-05 Takeda Chemical Industries, Ltd. Metastin derivatives and their use
CA2518541C (en) * 2003-03-12 2013-05-21 Takeda Pharmaceutical Company Limited Gonadal function improving agents
WO2005117939A2 (en) * 2004-04-23 2005-12-15 Applied Research Systems Ars Holding N.V. Use of gpcr54 ligands for the treatment of infertility
CA2571420A1 (en) * 2004-06-25 2006-01-05 Takeda Pharmaceutical Company Limited Metastin derivatives and use thereof
WO2007084211A2 (en) * 2005-11-11 2007-07-26 The General Hospital Corporation Use of gpr54 ligands for treatment of reproductive disorders, proliferative disorders, and for contraception
US20090093615A1 (en) * 2005-12-22 2009-04-09 Takeda Pharmaceutical Company Limited Metastin derivatives and use thereof
AR058584A1 (es) * 2005-12-22 2008-02-13 Takeda Pharmaceutical Derivados de metastina y uso de los mismos
US20090099334A1 (en) * 2005-12-22 2009-04-16 Takeda Pharmaceutical Company Limited Metastin derivatives and use thereof
US8404643B2 (en) * 2005-12-22 2013-03-26 Takeda Pharmaceutical Company Limited Metastin derivatives and use thereof
US20070244048A1 (en) * 2006-03-20 2007-10-18 Marsh Donald J Neuromedin U receptor agonists and uses thereof
AU2007231553B2 (en) * 2006-03-28 2012-10-25 Molecular Discovery Systems Agent for the treatment of hormone-dependent disorders and uses thereof
US8183212B2 (en) 2006-04-26 2012-05-22 Kyoto University Compound having GPR54 agonistic activity
JO3048B1 (ar) * 2006-10-25 2016-09-05 Takeda Pharmaceuticals Co مشتقات متاستين واستخدامها
JP4906476B2 (ja) 2006-11-06 2012-03-28 株式会社ブリヂストン タイヤ加硫モールドの洗浄方法
JP2009058102A (ja) 2007-09-03 2009-03-19 Akebono Brake Ind Co Ltd パッドクリップ及び多板ディスクブレーキ
JPWO2009044918A1 (ja) * 2007-10-05 2011-02-17 武田薬品工業株式会社 ニューロメジンu誘導体

Also Published As

Publication number Publication date
EP3210998A1 (en) 2017-08-30
LT2314609T (lt) 2017-04-10
HUE030900T2 (en) 2017-06-28
JP5698977B2 (ja) 2015-04-08
ES2617657T3 (es) 2017-06-19
HRP20170319T1 (hr) 2017-05-05
CY1118975T1 (el) 2018-01-10
DK2314609T3 (en) 2017-03-13
JPWO2010013762A1 (ja) 2012-01-12
PL2314609T3 (pl) 2017-07-31
WO2010013762A1 (ja) 2010-02-04
EP2314609A4 (en) 2013-01-16
EP2314609A1 (en) 2011-04-27
US20110212890A1 (en) 2011-09-01
EP2314609B1 (en) 2016-11-30
SI2314609T1 (sl) 2017-05-31

Similar Documents

Publication Publication Date Title
HRP20180718T1 (hr) Oligopeptidni spojevi i njihova upotreba
HK1196358A1 (en) Substituted pyridin-2-ones and pyridazin-3-ones -2--3-
IL211042A0 (en) Imidazopyridin-2-one derivatives and uses thereof
ZA201103635B (en) Azaquinolinone derivatives and uses thereof
EP2264017A4 (en) Heterocyclic derivative and its use
IL210804A (en) Benzylidenehydrazides and their uses
GB0818241D0 (en) Compounds and their use
EP2277900A4 (en) METASTIN DERIVATIVE AND USE THEREOF
IL208081A0 (en) Amido - thiophene compounds and their use
IL198046A0 (en) Metastin derivatives and use thereof
ZA201007395B (en) Aryl-quinolyl compounds and their use
SI2344449T1 (sl) Aril-fenil-sulfonamido-cikloalkilne spojine in njihova uporaba
IL208771A0 (en) Iminopyridine derivatives and use thereof
ZA201103456B (en) Leukolectins and uses thereof
EP2291377A4 (en) IMIDAZOPYRIMIDINONE AND ITS USES
EP2275433A4 (en) METASTIN DERIVATIVE AND USE THEREOF
PL2247601T3 (pl) Tiazopirymidynony i ich zastosowanie
EP2213675A4 (en) PYRIDOOXAZEPINE DERIVATIVE AND USE THEREOF
SI2314609T1 (sl) Derivat metastina in njegova uporaba
IL208824A0 (en) Iminopyridine derivative and use thereof
GB0801319D0 (en) Compounds and their use
ZA200902452B (en) Metastin derivatives and use thereof
IL206951A0 (en) 3-alkyl-piperazine derivatives and uses thereof
EP2274294A4 (en) 5-DIMETHOXY FUMAGILLOL AND ITS DERIVATIVES
GB0813359D0 (en) Halfin and/or platerfin