PT1934207E - Piperidinas 4-fenil substituídas para utilização como inibidores da renina - Google Patents

Piperidinas 4-fenil substituídas para utilização como inibidores da renina Download PDF

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Publication number
PT1934207E
PT1934207E PT07820887T PT07820887T PT1934207E PT 1934207 E PT1934207 E PT 1934207E PT 07820887 T PT07820887 T PT 07820887T PT 07820887 T PT07820887 T PT 07820887T PT 1934207 E PT1934207 E PT 1934207E
Authority
PT
Portugal
Prior art keywords
substituted
renin inhibitors
phenyl piperidines
piperidines
phenyl
Prior art date
Application number
PT07820887T
Other languages
English (en)
Inventor
Peter Herold
Robert Mah
Stefan Stutz
Tschinke Vincenzo
Aleksandar Stojanovic
Dirk Behnke
Nathalie Jotterand
Stjepan Jelakovic
Original Assignee
Novartis Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Novartis Ag filed Critical Novartis Ag
Publication of PT1934207E publication Critical patent/PT1934207E/pt

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
    • C07D413/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/12—Drugs for disorders of the urinary system of the kidneys
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A61P27/06—Antiglaucoma agents or miotics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Urology & Nephrology (AREA)
  • Ophthalmology & Optometry (AREA)
  • Hospice & Palliative Care (AREA)
  • Vascular Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
PT07820887T 2006-10-04 2007-10-03 Piperidinas 4-fenil substituídas para utilização como inibidores da renina PT1934207E (pt)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP06121772A EP1911758A1 (en) 2006-10-04 2006-10-04 Phenyl piperidine derivatives for use as renin inhibitors

Publications (1)

Publication Number Publication Date
PT1934207E true PT1934207E (pt) 2009-05-21

Family

ID=37946086

Family Applications (1)

Application Number Title Priority Date Filing Date
PT07820887T PT1934207E (pt) 2006-10-04 2007-10-03 Piperidinas 4-fenil substituídas para utilização como inibidores da renina

Country Status (18)

Country Link
US (1) US7625893B2 (pt)
EP (2) EP1911758A1 (pt)
JP (1) JP2009532443A (pt)
CN (1) CN101415703B (pt)
AR (1) AR063124A1 (pt)
AT (1) ATE425159T1 (pt)
BR (1) BRPI0716114A2 (pt)
CA (1) CA2642455A1 (pt)
DE (1) DE602007000679D1 (pt)
DK (1) DK1934207T3 (pt)
ES (1) ES2322629T3 (pt)
HK (1) HK1119678A1 (pt)
IL (1) IL193476A0 (pt)
PL (1) PL1934207T3 (pt)
PT (1) PT1934207E (pt)
SI (1) SI1934207T1 (pt)
TW (1) TW200831499A (pt)
WO (1) WO2008040764A1 (pt)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1863763A1 (en) * 2005-03-31 2007-12-12 Speedel Experimenta AG 3,4,5-substituted piperidines as renin inhibitors
TW200932241A (en) * 2007-12-05 2009-08-01 Speedel Experimenta Ag Organic compounds
TWI434690B (zh) 2007-12-19 2014-04-21 Dainippon Sumitomo Pharma Co 雜雙環衍生物
EA201001517A1 (ru) * 2008-04-02 2011-04-29 Новартис Аг Замещенные пиперидины в качестве терапевтических соединений
CA2765527A1 (en) 2009-06-24 2010-12-29 Satoshi Suetsugu N-substituted-cyclic amino derivative

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2031745A1 (en) * 1989-12-08 1991-06-09 William J. Greenlee Cyclic renin inhibitors containing 2-substituted(3s, 4s)-4-amino-5-cyclohexyl-3-hydroxy pentanoic acid, 2-substituted (3s, 4s)-5-cyclohexyl-3,4-dihydroxy-pentanoic acid or 2 -substituted (4s, 5s)-5-amino-6- yclohexyl-4-hydroxyhexanoic acid or its analogs
US5194605A (en) * 1989-12-08 1993-03-16 Merck & Co., Inc. Cyclic renin inhibitors containing 2-substituted (3S,4S)-4-amino-5-cyclohexyl-3-hydroxy pentanoic acid, 2-substituted (3S,4S)-5-cyclohexyl-3,4-di-hydroxy pentanoic acid or 2-substituted (4S,5S)-5-amino-6-cyclohexyl-4-hydroxyhexanoic acid or its analogs
US6376672B1 (en) * 1999-04-27 2002-04-23 Hoffmann-La Roche Inc. Naphthalenylmethoxypiperidines as renin inhibitors
US20040204455A1 (en) * 2003-04-10 2004-10-14 Cody Wayne Livingston Piperidine derivative rennin inhibitors
TW200613274A (en) * 2004-07-09 2006-05-01 Speedel Experimenta Ag Organic compounds

Also Published As

Publication number Publication date
DE602007000679D1 (de) 2009-04-23
ES2322629T3 (es) 2009-06-23
US7625893B2 (en) 2009-12-01
EP1911758A1 (en) 2008-04-16
WO2008040764A1 (en) 2008-04-10
SI1934207T1 (sl) 2009-08-31
PL1934207T3 (pl) 2009-10-30
HK1119678A1 (en) 2009-03-13
US20090088426A1 (en) 2009-04-02
TW200831499A (en) 2008-08-01
EP1934207B1 (en) 2009-03-11
EP1934207A1 (en) 2008-06-25
CA2642455A1 (en) 2008-04-10
CN101415703B (zh) 2012-04-25
BRPI0716114A2 (pt) 2013-09-24
CN101415703A (zh) 2009-04-22
ATE425159T1 (de) 2009-03-15
JP2009532443A (ja) 2009-09-10
AR063124A1 (es) 2008-12-30
DK1934207T3 (da) 2009-06-02
IL193476A0 (en) 2009-05-04

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