DE602007000679D1 - Substituierte 4-phenylpiperidine zur verwendung als renininhibitoren - Google Patents
Substituierte 4-phenylpiperidine zur verwendung als renininhibitorenInfo
- Publication number
- DE602007000679D1 DE602007000679D1 DE602007000679T DE602007000679T DE602007000679D1 DE 602007000679 D1 DE602007000679 D1 DE 602007000679D1 DE 602007000679 T DE602007000679 T DE 602007000679T DE 602007000679 T DE602007000679 T DE 602007000679T DE 602007000679 D1 DE602007000679 D1 DE 602007000679D1
- Authority
- DE
- Germany
- Prior art keywords
- renininhibitors
- phenylpiperidines
- substituted
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Active
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
- C07D413/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/12—Drugs for disorders of the urinary system of the kidneys
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
- A61P27/06—Antiglaucoma agents or miotics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Urology & Nephrology (AREA)
- Ophthalmology & Optometry (AREA)
- Hospice & Palliative Care (AREA)
- Vascular Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
EP06121772A EP1911758A1 (de) | 2006-10-04 | 2006-10-04 | Phenylpiperidinderivative zur Verwendung als Renin Inhibitoren |
PCT/EP2007/060510 WO2008040764A1 (en) | 2006-10-04 | 2007-10-03 | Substituted 4-phenyl piperidines for use as renin inhibitors |
Publications (1)
Publication Number | Publication Date |
---|---|
DE602007000679D1 true DE602007000679D1 (de) | 2009-04-23 |
Family
ID=37946086
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE602007000679T Active DE602007000679D1 (de) | 2006-10-04 | 2007-10-03 | Substituierte 4-phenylpiperidine zur verwendung als renininhibitoren |
Country Status (18)
Country | Link |
---|---|
US (1) | US7625893B2 (de) |
EP (2) | EP1911758A1 (de) |
JP (1) | JP2009532443A (de) |
CN (1) | CN101415703B (de) |
AR (1) | AR063124A1 (de) |
AT (1) | ATE425159T1 (de) |
BR (1) | BRPI0716114A2 (de) |
CA (1) | CA2642455A1 (de) |
DE (1) | DE602007000679D1 (de) |
DK (1) | DK1934207T3 (de) |
ES (1) | ES2322629T3 (de) |
HK (1) | HK1119678A1 (de) |
IL (1) | IL193476A0 (de) |
PL (1) | PL1934207T3 (de) |
PT (1) | PT1934207E (de) |
SI (1) | SI1934207T1 (de) |
TW (1) | TW200831499A (de) |
WO (1) | WO2008040764A1 (de) |
Families Citing this family (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP1863763A1 (de) * | 2005-03-31 | 2007-12-12 | Speedel Experimenta AG | 3,4,5-substituierte piperidine als reninhemmer |
TW200932241A (en) * | 2007-12-05 | 2009-08-01 | Speedel Experimenta Ag | Organic compounds |
TWI434690B (zh) | 2007-12-19 | 2014-04-21 | Dainippon Sumitomo Pharma Co | 雜雙環衍生物 |
EA201001517A1 (ru) * | 2008-04-02 | 2011-04-29 | Новартис Аг | Замещенные пиперидины в качестве терапевтических соединений |
CA2765527A1 (en) | 2009-06-24 | 2010-12-29 | Satoshi Suetsugu | N-substituted-cyclic amino derivative |
Family Cites Families (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CA2031745A1 (en) * | 1989-12-08 | 1991-06-09 | William J. Greenlee | Cyclic renin inhibitors containing 2-substituted(3s, 4s)-4-amino-5-cyclohexyl-3-hydroxy pentanoic acid, 2-substituted (3s, 4s)-5-cyclohexyl-3,4-dihydroxy-pentanoic acid or 2 -substituted (4s, 5s)-5-amino-6- yclohexyl-4-hydroxyhexanoic acid or its analogs |
US5194605A (en) * | 1989-12-08 | 1993-03-16 | Merck & Co., Inc. | Cyclic renin inhibitors containing 2-substituted (3S,4S)-4-amino-5-cyclohexyl-3-hydroxy pentanoic acid, 2-substituted (3S,4S)-5-cyclohexyl-3,4-di-hydroxy pentanoic acid or 2-substituted (4S,5S)-5-amino-6-cyclohexyl-4-hydroxyhexanoic acid or its analogs |
US6376672B1 (en) * | 1999-04-27 | 2002-04-23 | Hoffmann-La Roche Inc. | Naphthalenylmethoxypiperidines as renin inhibitors |
US20040204455A1 (en) * | 2003-04-10 | 2004-10-14 | Cody Wayne Livingston | Piperidine derivative rennin inhibitors |
TW200613274A (en) * | 2004-07-09 | 2006-05-01 | Speedel Experimenta Ag | Organic compounds |
-
2006
- 2006-10-04 EP EP06121772A patent/EP1911758A1/de not_active Ceased
-
2007
- 2007-10-02 TW TW096136831A patent/TW200831499A/zh unknown
- 2007-10-03 JP JP2009503599A patent/JP2009532443A/ja active Pending
- 2007-10-03 CN CN2007800123423A patent/CN101415703B/zh not_active Expired - Fee Related
- 2007-10-03 AR ARP070104392A patent/AR063124A1/es unknown
- 2007-10-03 EP EP07820887A patent/EP1934207B1/de not_active Not-in-force
- 2007-10-03 SI SI200730031T patent/SI1934207T1/sl unknown
- 2007-10-03 DK DK07820887T patent/DK1934207T3/da active
- 2007-10-03 ES ES07820887T patent/ES2322629T3/es active Active
- 2007-10-03 PT PT07820887T patent/PT1934207E/pt unknown
- 2007-10-03 PL PL07820887T patent/PL1934207T3/pl unknown
- 2007-10-03 WO PCT/EP2007/060510 patent/WO2008040764A1/en active Application Filing
- 2007-10-03 AT AT07820887T patent/ATE425159T1/de active
- 2007-10-03 BR BRPI0716114-0A2A patent/BRPI0716114A2/pt not_active IP Right Cessation
- 2007-10-03 US US12/224,440 patent/US7625893B2/en not_active Expired - Fee Related
- 2007-10-03 DE DE602007000679T patent/DE602007000679D1/de active Active
- 2007-10-03 CA CA002642455A patent/CA2642455A1/en not_active Abandoned
-
2008
- 2008-08-14 IL IL193476A patent/IL193476A0/en unknown
- 2008-10-22 HK HK08111638.7A patent/HK1119678A1/xx unknown
Also Published As
Publication number | Publication date |
---|---|
ES2322629T3 (es) | 2009-06-23 |
US7625893B2 (en) | 2009-12-01 |
EP1911758A1 (de) | 2008-04-16 |
WO2008040764A1 (en) | 2008-04-10 |
SI1934207T1 (sl) | 2009-08-31 |
PL1934207T3 (pl) | 2009-10-30 |
HK1119678A1 (en) | 2009-03-13 |
US20090088426A1 (en) | 2009-04-02 |
TW200831499A (en) | 2008-08-01 |
EP1934207B1 (de) | 2009-03-11 |
EP1934207A1 (de) | 2008-06-25 |
CA2642455A1 (en) | 2008-04-10 |
CN101415703B (zh) | 2012-04-25 |
PT1934207E (pt) | 2009-05-21 |
BRPI0716114A2 (pt) | 2013-09-24 |
CN101415703A (zh) | 2009-04-22 |
ATE425159T1 (de) | 2009-03-15 |
JP2009532443A (ja) | 2009-09-10 |
AR063124A1 (es) | 2008-12-30 |
DK1934207T3 (da) | 2009-06-02 |
IL193476A0 (en) | 2009-05-04 |
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DE602007000679D1 (de) | Substituierte 4-phenylpiperidine zur verwendung als renininhibitoren |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
8327 | Change in the person/name/address of the patent owner |
Owner name: NOVARTIS AG, BASEL, CH |
|
8364 | No opposition during term of opposition |