PT1771474E - Inibidores de proteína 4 do tipo angiopoietina, combinações e sua utilização - Google Patents

Inibidores de proteína 4 do tipo angiopoietina, combinações e sua utilização Download PDF

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Publication number
PT1771474E
PT1771474E PT05790352T PT05790352T PT1771474E PT 1771474 E PT1771474 E PT 1771474E PT 05790352 T PT05790352 T PT 05790352T PT 05790352 T PT05790352 T PT 05790352T PT 1771474 E PT1771474 E PT 1771474E
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Prior art keywords
angptl4
antagonist
antibody
quot
cells
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PT05790352T
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English (en)
Portuguese (pt)
Inventor
Napoleone Ferrara
Hans-Peter Gerber
Xiao Huan Liang
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Genentech Inc
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Publication of PT1771474E publication Critical patent/PT1771474E/pt

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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/395Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/22Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against growth factors ; against growth regulators
    • AHUMAN NECESSITIES
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    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/18Growth factors; Growth regulators
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    • AHUMAN NECESSITIES
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    • A61P9/08Vasodilators for multiple indications
    • AHUMAN NECESSITIES
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    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/10Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/12Antihypertensives
    • AHUMAN NECESSITIES
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    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/14Vasoprotectives; Antihaemorrhoidals; Drugs for varicose therapy; Capillary stabilisers
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2839Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the integrin superfamily
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/505Medicinal preparations containing antigens or antibodies comprising antibodies
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/70Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C07K2317/73Inducing cell death, e.g. apoptosis, necrosis or inhibition of cell proliferation
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/70Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C07K2317/76Antagonist effect on antigen, e.g. neutralization or inhibition of binding

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  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Immunology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biophysics (AREA)
  • Cardiology (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Biochemistry (AREA)
  • Reproductive Health (AREA)
  • Urology & Nephrology (AREA)
  • Endocrinology (AREA)
  • Dermatology (AREA)
  • Ophthalmology & Optometry (AREA)
  • Oncology (AREA)
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  • Epidemiology (AREA)
  • Diabetes (AREA)
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  • Hematology (AREA)
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  • Pregnancy & Childbirth (AREA)
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  • Orthopedic Medicine & Surgery (AREA)
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PT05790352T 2004-07-20 2005-07-19 Inibidores de proteína 4 do tipo angiopoietina, combinações e sua utilização PT1771474E (pt)

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US58978204P 2004-07-20 2004-07-20

Publications (1)

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PT1771474E true PT1771474E (pt) 2010-05-03

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PT05790352T PT1771474E (pt) 2004-07-20 2005-07-19 Inibidores de proteína 4 do tipo angiopoietina, combinações e sua utilização

Country Status (23)

Country Link
US (2) US7740846B2 (OSRAM)
EP (3) EP2361931B1 (OSRAM)
JP (2) JP4947717B2 (OSRAM)
KR (1) KR101254815B1 (OSRAM)
CN (2) CN102641503A (OSRAM)
AT (1) ATE456579T1 (OSRAM)
AU (2) AU2005269716B2 (OSRAM)
BR (1) BRPI0513534A (OSRAM)
CA (1) CA2574758A1 (OSRAM)
CY (1) CY1109931T1 (OSRAM)
DE (1) DE602005019167D1 (OSRAM)
DK (1) DK1771474T3 (OSRAM)
ES (1) ES2339789T3 (OSRAM)
IL (1) IL180725A0 (OSRAM)
MX (1) MX2007000784A (OSRAM)
NO (1) NO20070951L (OSRAM)
NZ (1) NZ552956A (OSRAM)
PL (1) PL1771474T3 (OSRAM)
PT (1) PT1771474E (OSRAM)
RU (1) RU2392966C2 (OSRAM)
SI (1) SI1771474T1 (OSRAM)
WO (1) WO2006014729A2 (OSRAM)
ZA (1) ZA200701183B (OSRAM)

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