PT1680140E - Inibidores do receptor-1 do factor de crescimento de fibroblastos e m?todos de tratamento destes - Google Patents

Inibidores do receptor-1 do factor de crescimento de fibroblastos e m?todos de tratamento destes Download PDF

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Publication number
PT1680140E
PT1680140E PT04796034T PT04796034T PT1680140E PT 1680140 E PT1680140 E PT 1680140E PT 04796034 T PT04796034 T PT 04796034T PT 04796034 T PT04796034 T PT 04796034T PT 1680140 E PT1680140 E PT 1680140E
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Portugal
Prior art keywords
fgfr
methods
treatment
growth factor
factor receptor
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PT04796034T
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English (en)
Inventor
Haijun Sun
Juqun Shen
James R Tonra
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Imclone Llc
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Publication of PT1680140E publication Critical patent/PT1680140E/pt

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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2863—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against receptors for growth factors, growth regulators
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    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
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    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/55—Fab or Fab'
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/56—Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/56—Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
    • C07K2317/565—Complementarity determining region [CDR]
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C07K2317/73—Inducing cell death, e.g. apoptosis, necrosis or inhibition of cell proliferation
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C07K2317/76—Antagonist effect on antigen, e.g. neutralization or inhibition of binding

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  • Animal Behavior & Ethology (AREA)
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  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
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  • Immunology (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Cardiology (AREA)
  • Epidemiology (AREA)
  • Obesity (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Urology & Nephrology (AREA)
  • Rheumatology (AREA)
  • Neurosurgery (AREA)
  • Reproductive Health (AREA)
  • Dermatology (AREA)
  • Endocrinology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Pain & Pain Management (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Vascular Medicine (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Gynecology & Obstetrics (AREA)
PT04796034T 2003-10-16 2004-10-18 Inibidores do receptor-1 do factor de crescimento de fibroblastos e m?todos de tratamento destes PT1680140E (pt)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US51225503P 2003-10-16 2003-10-16

Publications (1)

Publication Number Publication Date
PT1680140E true PT1680140E (pt) 2011-05-31

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ID=34465334

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PT04796034T PT1680140E (pt) 2003-10-16 2004-10-18 Inibidores do receptor-1 do factor de crescimento de fibroblastos e m?todos de tratamento destes

Country Status (13)

Country Link
US (2) US20070274981A1 (pt)
EP (3) EP2229955A1 (pt)
JP (1) JP4686465B2 (pt)
AT (1) ATE506077T1 (pt)
CA (2) CA2542638A1 (pt)
CY (1) CY1111479T1 (pt)
DE (1) DE602004032370D1 (pt)
DK (1) DK1680140T3 (pt)
ES (1) ES2361917T3 (pt)
PL (1) PL1680140T3 (pt)
PT (1) PT1680140E (pt)
SI (1) SI1680140T1 (pt)
WO (1) WO2005037235A2 (pt)

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US20070274981A1 (en) 2007-11-29
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