SE0001285D0 - Djur- och cellmodeller för diabetes typ II och deras användning - Google Patents

Djur- och cellmodeller för diabetes typ II och deras användning

Info

Publication number
SE0001285D0
SE0001285D0 SE0001285A SE0001285A SE0001285D0 SE 0001285 D0 SE0001285 D0 SE 0001285D0 SE 0001285 A SE0001285 A SE 0001285A SE 0001285 A SE0001285 A SE 0001285A SE 0001285 D0 SE0001285 D0 SE 0001285D0
Authority
SE
Sweden
Prior art keywords
diabetes
type
fgfr1c
beta
cells
Prior art date
Application number
SE0001285A
Other languages
English (en)
Inventor
Helena Edlund
Alan Hart
Nathalie Baeza
Aasa Apelqvist
Original Assignee
Elinus Ab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Elinus Ab filed Critical Elinus Ab
Priority to SE0001285A priority Critical patent/SE0001285D0/sv
Publication of SE0001285D0 publication Critical patent/SE0001285D0/sv
Priority to AU2001247022A priority patent/AU2001247022B2/en
Priority to AU4702201A priority patent/AU4702201A/xx
Priority to US10/257,155 priority patent/US7098375B2/en
Priority to IL15213501A priority patent/IL152135A0/xx
Priority to JP2001573893A priority patent/JP2003529379A/ja
Priority to EP01920077A priority patent/EP1292186A1/en
Priority to CA002414652A priority patent/CA2414652A1/en
Priority to MXPA02009900A priority patent/MXPA02009900A/es
Priority to PCT/SE2001/000783 priority patent/WO2001076361A1/en
Priority to ZA200208694A priority patent/ZA200208694B/xx

Links

Classifications

    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
    • A01K67/00—Rearing or breeding animals, not otherwise provided for; New or modified breeds of animals
    • A01K67/027—New or modified breeds of vertebrates
    • A01K67/0275—Genetically modified vertebrates, e.g. transgenic
    • A01K67/0276—Knock-out vertebrates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • C07K14/71—Receptors; Cell surface antigens; Cell surface determinants for growth factors; for growth regulators
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/85—Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
    • C12N15/8509—Vectors or expression systems specially adapted for eukaryotic hosts for animal cells for producing genetically modified animals, e.g. transgenic
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
    • A01K2217/00—Genetically modified animals
    • A01K2217/07—Animals genetically altered by homologous recombination
    • A01K2217/075—Animals genetically altered by homologous recombination inducing loss of function, i.e. knock out
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
    • A01K2227/00—Animals characterised by species
    • A01K2227/10—Mammal
    • A01K2227/105—Murine
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
    • A01K2267/00—Animals characterised by purpose
    • A01K2267/03—Animal model, e.g. for test or diseases
    • A01K2267/0306—Animal model for genetic diseases
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
    • A01K2267/00—Animals characterised by purpose
    • A01K2267/03—Animal model, e.g. for test or diseases
    • A01K2267/035—Animal model for multifactorial diseases
    • A01K2267/0362—Animal model for lipid/glucose metabolism, e.g. obesity, type-2 diabetes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K48/00—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2517/00—Cells related to new breeds of animals
    • C12N2517/02—Cells from transgenic animals

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Zoology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Veterinary Medicine (AREA)
  • Biotechnology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Environmental Sciences (AREA)
  • Wood Science & Technology (AREA)
  • Molecular Biology (AREA)
  • General Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Biomedical Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Diabetes (AREA)
  • Toxicology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Animal Husbandry (AREA)
  • Cell Biology (AREA)
  • Immunology (AREA)
  • Plant Pathology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Physics & Mathematics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Microbiology (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Biodiversity & Conservation Biology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Obesity (AREA)
  • Hematology (AREA)
  • Endocrinology (AREA)
  • Emergency Medicine (AREA)
SE0001285A 2000-04-07 2000-04-07 Djur- och cellmodeller för diabetes typ II och deras användning SE0001285D0 (sv)

Priority Applications (11)

Application Number Priority Date Filing Date Title
SE0001285A SE0001285D0 (sv) 2000-04-07 2000-04-07 Djur- och cellmodeller för diabetes typ II och deras användning
PCT/SE2001/000783 WO2001076361A1 (en) 2000-04-07 2001-04-06 Animal and cell models for type ii diabetes and their use
IL15213501A IL152135A0 (en) 2000-04-07 2001-04-06 Animal and cell models for type ii diabetes and their use
AU4702201A AU4702201A (en) 2000-04-07 2001-04-06 Animal and cell models for type ii diabetes and their use
US10/257,155 US7098375B2 (en) 2000-04-07 2001-04-06 Animal and cell models for type II diabetes and their use
AU2001247022A AU2001247022B2 (en) 2000-04-07 2001-04-06 Animal and cell models for type II diabetes and their use
JP2001573893A JP2003529379A (ja) 2000-04-07 2001-04-06 Ｉｉ型糖尿病の動物および細胞モデルとその使用
EP01920077A EP1292186A1 (en) 2000-04-07 2001-04-06 Animal and cell models for type ii diabetes and their use
CA002414652A CA2414652A1 (en) 2000-04-07 2001-04-06 Animal and cell models for type ii diabetes and their use
MXPA02009900A MXPA02009900A (es) 2000-04-07 2001-04-06 Modelos celulares y animales para diabetes tipo ii y su uso.
ZA200208694A ZA200208694B (en) 2000-04-07 2002-10-28 Animal and cell models for type II diabetes and their use.

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
SE0001285A SE0001285D0 (sv) 2000-04-07 2000-04-07 Djur- och cellmodeller för diabetes typ II och deras användning

Publications (1)

Publication Number Publication Date
SE0001285D0 true SE0001285D0 (sv) 2000-04-07

Family

ID=20279221

Family Applications (1)

Application Number Title Priority Date Filing Date
SE0001285A SE0001285D0 (sv) 2000-04-07 2000-04-07 Djur- och cellmodeller för diabetes typ II och deras användning

Country Status (10)

Country Link
US (1) US7098375B2 (sv)
EP (1) EP1292186A1 (sv)
JP (1) JP2003529379A (sv)
AU (2) AU2001247022B2 (sv)
CA (1) CA2414652A1 (sv)
IL (1) IL152135A0 (sv)
MX (1) MXPA02009900A (sv)
SE (1) SE0001285D0 (sv)
WO (1) WO2001076361A1 (sv)
ZA (1) ZA200208694B (sv)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2004264314A1 (en) * 2003-08-18 2005-02-24 Betagenon Ab New diabetes type 2 animal model
JP4686465B2 (ja) * 2003-10-16 2011-05-25 イムクローン・リミテッド・ライアビリティ・カンパニー 繊維芽細胞増殖因子レセプター−１阻害物質及びその治療方法
CN114832107A (zh) * 2022-04-25 2022-08-02 上海交通大学医学院附属瑞金医院 mTORC1在制备β细胞代偿药物中的应用

Also Published As

Publication number Publication date
JP2003529379A (ja) 2003-10-07
EP1292186A1 (en) 2003-03-19
WO2001076361A1 (en) 2001-10-18
IL152135A0 (en) 2003-05-29
AU2001247022B2 (en) 2005-11-17
US20030056240A1 (en) 2003-03-20
MXPA02009900A (es) 2004-09-06
US7098375B2 (en) 2006-08-29
ZA200208694B (en) 2003-08-19
CA2414652A1 (en) 2001-10-18
AU4702201A (en) 2001-10-23

Similar Documents

Publication Publication Date Title
DE69231947D1 (de) Genherstellung zur produktion von transgenfisch
GR3023547T3 (en) Plant cultivation method and apparatus.
WO1999005266A3 (en) Trans-species nuclear transfer
HK1044174A1 (zh) 通過胞質內精子注射進行哺乳動物基因轉移
ATE469654T1 (de) Verwendung des erythropoietins zur regeneration von lebergewebe
DE50305942D1 (de) Polymerisationsfähige bicyclische Cyclopropanderivate und deren Verwendung zur Herstellung von Dentalmaterialien
DE69735293D1 (de) Kultur einer zelllinieaus der inneren zellmasse von huftierembryonen.
ATE12255T1 (de) Verfahren zur herstellung von selbstreproduzierenden pankreatischen inseln aehnlichen strukturen von saeugetieren.
AR077485A2 (es) Difenilureas substituidas con carboxiarilo como inhibidores de raf quinasa
ATE188736T1 (de) Endothelin-dna und verwendung davon
DK0815200T3 (da) Værtscelle, der udtrykker reduceret niveau af en metalloprotease, og fremgangsmåder, der anvender værtscellen i proteinproduktion
DE69832716D1 (de) Herstellung embryonischer vogel keimzellinien durch verlängerte kultivierung von pgcs, verwendung desselben zur klonierung und chimerisierung
DE69911584D1 (de) Pilzbrut
SE0001285D0 (sv) Djur- och cellmodeller för diabetes typ II och deras användning
ES2026524T3 (es) Metodo y aparato para cultivos hidroponicos.
ATE310801T1 (de) Kulturvorrichtung und verfahren zur kultivierung von zellen oder gewebekomponenten
DK363088D0 (da) Dobbeltstrenget rna-korrektion af afvigende metaboliske baner, der staar i forbindelse med ukontrollerede tumorcelle- og virusvaekstcykler
ATE203241T1 (de) Verfahren zur herstellung von 3-isochromanon
ATE192492T1 (de) Transformierte endothelzellen
WO2004015091A3 (en) Preparation of type ii pneumocytes from stem cells
DE50013563D1 (de) Verwendung von pankreatischer Procarboxypeptidase B zur Herstellung von Insulin
JPS57115194A (en) Preparation of human parathyroid hormone
ATE384790T1 (de) Uroplakin-ii-promotor aus schwein und verfahren zur herstellung nützlicher proteine unter verwendung des promotors
DE59914540D1 (de) Transgene pflanzen und pflanzenzellen mit verminderter expression von invertaseinhibitoren
Weiss et al. Conservation of salmonid fishes in Austria: current status and future strategies