WO2006073587A3 - Hemipteran 5-hydroxytryptamine 7 serotonin receptor - Google Patents

Hemipteran 5-hydroxytryptamine 7 serotonin receptor Download PDF

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Publication number
WO2006073587A3
WO2006073587A3 PCT/US2005/041892 US2005041892W WO2006073587A3 WO 2006073587 A3 WO2006073587 A3 WO 2006073587A3 US 2005041892 W US2005041892 W US 2005041892W WO 2006073587 A3 WO2006073587 A3 WO 2006073587A3
Authority
WO
WIPO (PCT)
Prior art keywords
serotonin receptor
disclosed
hemipteran
hydroxytryptamine
methods
Prior art date
Application number
PCT/US2005/041892
Other languages
French (fr)
Other versions
WO2006073587A2 (en
Inventor
Debra A Yuhas
Jeffrey D Herron
Original Assignee
Fmc Corp
Debra A Yuhas
Jeffrey D Herron
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Fmc Corp, Debra A Yuhas, Jeffrey D Herron filed Critical Fmc Corp
Publication of WO2006073587A2 publication Critical patent/WO2006073587A2/en
Publication of WO2006073587A3 publication Critical patent/WO2006073587A3/en

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    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705Receptors; Cell surface antigens; Cell surface determinants
    • C07K14/70571Receptors; Cell surface antigens; Cell surface determinants for neuromediators, e.g. serotonin receptor, dopamine receptor
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/43504Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from invertebrates
    • C07K14/43563Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from invertebrates from insects
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/94Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving narcotics or drugs or pharmaceuticals, neurotransmitters or associated receptors
    • G01N33/9406Neurotransmitters
    • G01N33/942Serotonin, i.e. 5-hydroxy-tryptamine
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2500/00Screening for compounds of potential therapeutic value

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Organic Chemistry (AREA)
  • Immunology (AREA)
  • Biomedical Technology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Zoology (AREA)
  • Medicinal Chemistry (AREA)
  • Urology & Nephrology (AREA)
  • Genetics & Genomics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biophysics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Toxicology (AREA)
  • Hematology (AREA)
  • Cell Biology (AREA)
  • Physics & Mathematics (AREA)
  • Microbiology (AREA)
  • Insects & Arthropods (AREA)
  • General Physics & Mathematics (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Analytical Chemistry (AREA)
  • Food Science & Technology (AREA)
  • Pathology (AREA)
  • Biotechnology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Neurology (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)

Abstract

Novel nucleic acid sequences encoding the 5 HT-7 serotonin receptor, and recombinant expressions and host cells comprising the same are disclosed. Isolated the 5 HT-7 serotonin receptor, host cells expressing the 5 HT-7 serotonin receptor, methods of producing the 5 HT-7 serotonin receptor and antibodies specific for the 5 HT-7 serotonin receptor are also disclosed. Methods of identifying activators, inhibitors or of the 5 HT-7 serotonin receptor are disclosed.
PCT/US2005/041892 2004-11-23 2005-11-18 Hemipteran 5-hydroxytryptamine 7 serotonin receptor WO2006073587A2 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US63051804P 2004-11-23 2004-11-23
US60/630,518 2004-11-23

Publications (2)

Publication Number Publication Date
WO2006073587A2 WO2006073587A2 (en) 2006-07-13
WO2006073587A3 true WO2006073587A3 (en) 2009-05-07

Family

ID=36647944

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2005/041892 WO2006073587A2 (en) 2004-11-23 2005-11-18 Hemipteran 5-hydroxytryptamine 7 serotonin receptor

Country Status (1)

Country Link
WO (1) WO2006073587A2 (en)

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
WITZ ET AL.: "Cloning and characterization of a drosophila serotonin receptor that activates adenylate cyclase.", PROC. NATL. ACAD. SCI. USA, vol. 87, November 1990 (1990-11-01), pages 8940 - 8944 *

Also Published As

Publication number Publication date
WO2006073587A2 (en) 2006-07-13

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