PT1567140E - Combinação sinérgica compreendendo roflumilaste e (r,r)-formoterol - Google Patents

Combinação sinérgica compreendendo roflumilaste e (r,r)-formoterol Download PDF

Info

Publication number
PT1567140E
PT1567140E PT03780056T PT03780056T PT1567140E PT 1567140 E PT1567140 E PT 1567140E PT 03780056 T PT03780056 T PT 03780056T PT 03780056 T PT03780056 T PT 03780056T PT 1567140 E PT1567140 E PT 1567140E
Authority
PT
Portugal
Prior art keywords
roflumilast
formoterol
synergistic combination
treatment
relates
Prior art date
Application number
PT03780056T
Other languages
English (en)
Portuguese (pt)
Inventor
Stefan-Lutz Wollin
Daniela Bundschuh
Rolf Beume
Christian Weimar
Degenhard Marx
Original Assignee
Nycomed Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Nycomed Gmbh filed Critical Nycomed Gmbh
Publication of PT1567140E publication Critical patent/PT1567140E/pt

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/16—Amides, e.g. hydroxamic acids
    • A61K31/165—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide
    • A61K31/167—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide having the nitrogen of a carboxamide group directly attached to the aromatic ring, e.g. lidocaine, paracetamol
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/06—Antiasthmatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/08—Bronchodilators

Landscapes

  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Pulmonology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Pain & Pain Management (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
PT03780056T 2002-11-27 2003-11-26 Combinação sinérgica compreendendo roflumilaste e (r,r)-formoterol PT1567140E (pt)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP02026504 2002-11-27

Publications (1)

Publication Number Publication Date
PT1567140E true PT1567140E (pt) 2008-09-24

Family

ID=32338001

Family Applications (1)

Application Number Title Priority Date Filing Date
PT03780056T PT1567140E (pt) 2002-11-27 2003-11-26 Combinação sinérgica compreendendo roflumilaste e (r,r)-formoterol

Country Status (31)

Country Link
US (1) US20060199865A1 (enExample)
EP (1) EP1567140B1 (enExample)
JP (1) JP2006508993A (enExample)
KR (1) KR20050094810A (enExample)
CN (1) CN1713902A (enExample)
AT (1) ATE399544T1 (enExample)
AU (1) AU2003288169B8 (enExample)
BR (1) BR0316475A (enExample)
CA (1) CA2506956C (enExample)
CO (1) CO5690571A2 (enExample)
CY (1) CY1110368T1 (enExample)
DE (1) DE60321954D1 (enExample)
DK (1) DK1567140T3 (enExample)
EA (1) EA009990B1 (enExample)
ES (1) ES2309374T3 (enExample)
HR (1) HRP20050580B1 (enExample)
IL (1) IL168307A (enExample)
IS (1) IS2576B (enExample)
MA (1) MA27538A1 (enExample)
ME (1) ME00488B (enExample)
MX (1) MXPA05005438A (enExample)
NO (1) NO334148B1 (enExample)
NZ (1) NZ540658A (enExample)
PL (1) PL214869B1 (enExample)
PT (1) PT1567140E (enExample)
RS (1) RS51082B (enExample)
SI (1) SI1567140T1 (enExample)
TN (1) TNSN05130A1 (enExample)
UA (1) UA83017C2 (enExample)
WO (1) WO2004047828A1 (enExample)
ZA (1) ZA200503307B (enExample)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
MY140561A (en) 2002-02-20 2009-12-31 Nycomed Gmbh Dosage form containing pde 4 inhibitor as active ingredient
ES2335498T3 (es) 2003-03-10 2010-03-29 Nycomed Gmbh Nuevo proceso para la preparacion de reflumilast.
JP5383183B2 (ja) 2005-03-16 2014-01-08 タケダ ゲゼルシャフト ミット ベシュレンクテル ハフツング ロフルミラストを含有する矯味された剤形
WO2013077830A1 (en) * 2011-11-25 2013-05-30 Mahmut Bilgic Synergistilly active combinations of roflumilast and carmoterol
CN103784443A (zh) * 2014-02-18 2014-05-14 青岛市城阳区人民医院 一种包含沙美特罗和罗氟司特的药物组合产品

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5795564A (en) * 1991-04-05 1998-08-18 Sepracor, Inc. Methods and compositions for treating pulmonary disorders using optically pure (R,R)-formoterol
CA2271004C (en) * 1996-11-11 2007-05-01 Sepracor Inc. Process for the preparation of optically pure isomers of formoterol
DE69835594T2 (de) * 1997-02-17 2007-08-16 Altana Pharma Ag Zusammensetzungen zur behandlung von irds oder ards die 3-(cyclopropylmethoxy)-n-(3,5-dichloro-4-pyridinyl)-4-(difluoromethoxy) benzamid und lungensurfactant enthalten
ES2302350T3 (es) * 1997-02-28 2008-07-01 Nycomed Gmbh Combinacion sinergica de inhibidores de pde y agonistas de adenilatociclasa o agonistas de guanililciclasa.
US6624181B1 (en) * 1997-02-28 2003-09-23 Altana Pharma Ag Synergistic combination
HUP0103160A3 (en) * 1998-08-26 2002-11-28 Smithkline Beecham Corp Pharmaceutical compositions for treating pulmonary diseases containing pde4 inhibitor
US6303145B2 (en) * 1999-05-10 2001-10-16 Sepracor Inc. (S,R) formoterol methods and compositions
ATE320800T1 (de) * 1999-08-21 2006-04-15 Altana Pharma Ag Synergistische kombination von roflumilast und salmeterol
GB0103630D0 (en) * 2001-02-14 2001-03-28 Glaxo Group Ltd Chemical compounds
DE60224172T2 (de) * 2001-03-22 2008-12-04 Glaxo Group Ltd., Greenford Formanilid-derivative als beta2-adrenorezeptor-agonisten
KR100831534B1 (ko) * 2001-04-30 2008-05-22 글락소 그룹 리미티드 17.알파 위치에 시클릭 에스테르기를 지닌 항염증성의안드로스탄의 17.베타.-카르보티오에이트 에스테르 유도체

Also Published As

Publication number Publication date
EP1567140A1 (en) 2005-08-31
AU2003288169B2 (en) 2010-01-07
EA009990B1 (ru) 2008-04-28
NZ540658A (en) 2007-03-30
TNSN05130A1 (en) 2007-05-14
AU2003288169B8 (en) 2010-08-26
ZA200503307B (en) 2006-11-29
RS20050383A (sr) 2007-08-03
CY1110368T1 (el) 2015-04-29
US20060199865A1 (en) 2006-09-07
EA200500865A1 (ru) 2005-12-29
MA27538A1 (fr) 2005-09-01
ME00488B (me) 2011-10-10
CA2506956C (en) 2012-10-02
CN1713902A (zh) 2005-12-28
CO5690571A2 (es) 2006-10-31
MXPA05005438A (es) 2005-08-03
SI1567140T1 (sl) 2008-12-31
ATE399544T1 (de) 2008-07-15
NO334148B1 (no) 2013-12-16
DK1567140T3 (da) 2008-11-03
NO20053023L (no) 2005-06-20
WO2004047828A1 (en) 2004-06-10
AU2003288169A1 (en) 2004-06-18
IS7899A (is) 2005-06-20
PL214869B1 (pl) 2013-09-30
CA2506956A1 (en) 2004-06-10
IL168307A (en) 2010-12-30
HK1081862A1 (en) 2006-05-26
EP1567140B1 (en) 2008-07-02
HRP20050580A2 (en) 2006-08-31
HRP20050580B1 (hr) 2014-04-11
IS2576B (is) 2010-02-15
PL375632A1 (en) 2005-12-12
DE60321954D1 (de) 2008-08-14
ES2309374T3 (es) 2008-12-16
UA83017C2 (uk) 2008-06-10
BR0316475A (pt) 2005-10-11
RS51082B (sr) 2010-10-31
JP2006508993A (ja) 2006-03-16
KR20050094810A (ko) 2005-09-28

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