CO5690571A2 - Combinacion sinergica que comprende roflumilas y (r,r)-formoterol - Google Patents

Combinacion sinergica que comprende roflumilas y (r,r)-formoterol

Info

Publication number
CO5690571A2
CO5690571A2 CO05062790A CO05062790A CO5690571A2 CO 5690571 A2 CO5690571 A2 CO 5690571A2 CO 05062790 A CO05062790 A CO 05062790A CO 05062790 A CO05062790 A CO 05062790A CO 5690571 A2 CO5690571 A2 CO 5690571A2
Authority
CO
Colombia
Prior art keywords
formoterol
roflumilas
combination including
synergic combination
synergic
Prior art date
Application number
CO05062790A
Other languages
English (en)
Inventor
Rolf Beume
Daniela Bundschuh
Degenhard Marx
Christian Weimar
Stefan-Lutz Wollin
Original Assignee
Altana Pharma Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Altana Pharma Ag filed Critical Altana Pharma Ag
Publication of CO5690571A2 publication Critical patent/CO5690571A2/es

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44Non condensed pyridines; Hydrogenated derivatives thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/16Amides, e.g. hydroxamic acids
    • A61K31/165Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide
    • A61K31/167Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide having the nitrogen of a carboxamide group directly attached to the aromatic ring, e.g. lidocaine, paracetamol
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • A61P11/06Antiasthmatics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • A61P11/08Bronchodilators

Landscapes

  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Pulmonology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pain & Pain Management (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

1.- El uso combinado de roflumilast y R,R-formoterol en la prevención de síntomas de, o el tratamiento de una deficiencia del tracto respiratorio en seres humanos.2.- El uso combinado de roflumilast y R,R-formoterol en la prevención de síntomas de, o el tratamiento de una deficiencia del tracto respiratorio en seres humanos, que comprende administrar roflumilast en una dosificación diaria desde 100 hasta 500 µg y R,R-formoterol en una dosificación diaria desde 10 hasta 120 µg.3.- Un medicamento adecuado para el uso combinado de acuerdo con la reivindicación 1 o 2, que comprende roflumilast y R,R-formoterol en combinación fija o libre.4.- El medicamento de acuerdo con la reivindicación 3, que es una combinación fija o libre.5.- El medicamento de acuerdo con la reivindicación 3, que es una combinación fija oral que contiene roflumilast en una dosificación diaria desde 100 hasta 500 µg y R,R-formoterol en una dosificación diaria desde 10 hasta 120 µg.
CO05062790A 2002-11-27 2005-06-27 Combinacion sinergica que comprende roflumilas y (r,r)-formoterol CO5690571A2 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP02026504 2002-11-27

Publications (1)

Publication Number Publication Date
CO5690571A2 true CO5690571A2 (es) 2006-10-31

Family

ID=32338001

Family Applications (1)

Application Number Title Priority Date Filing Date
CO05062790A CO5690571A2 (es) 2002-11-27 2005-06-27 Combinacion sinergica que comprende roflumilas y (r,r)-formoterol

Country Status (32)

Country Link
US (1) US20060199865A1 (es)
EP (1) EP1567140B1 (es)
JP (1) JP2006508993A (es)
KR (1) KR20050094810A (es)
CN (1) CN1713902A (es)
AT (1) ATE399544T1 (es)
AU (1) AU2003288169B8 (es)
BR (1) BR0316475A (es)
CA (1) CA2506956C (es)
CO (1) CO5690571A2 (es)
CY (1) CY1110368T1 (es)
DE (1) DE60321954D1 (es)
DK (1) DK1567140T3 (es)
EA (1) EA009990B1 (es)
ES (1) ES2309374T3 (es)
HK (1) HK1081862A1 (es)
HR (1) HRP20050580B1 (es)
IL (1) IL168307A (es)
IS (1) IS2576B (es)
MA (1) MA27538A1 (es)
ME (1) ME00488B (es)
MX (1) MXPA05005438A (es)
NO (1) NO334148B1 (es)
NZ (1) NZ540658A (es)
PL (1) PL214869B1 (es)
PT (1) PT1567140E (es)
RS (1) RS51082B (es)
SI (1) SI1567140T1 (es)
TN (1) TNSN05130A1 (es)
UA (1) UA83017C2 (es)
WO (1) WO2004047828A1 (es)
ZA (1) ZA200503307B (es)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
MY140561A (en) 2002-02-20 2009-12-31 Nycomed Gmbh Dosage form containing pde 4 inhibitor as active ingredient
ME00524B (me) 2003-03-10 2011-10-10 Astrazeneca Ab Novi postupak za dobijanje roflumilasta
CA2601250C (en) 2005-03-16 2014-10-28 Nycomed Gmbh Taste masked dosage form containing roflumilast
WO2013077830A1 (en) * 2011-11-25 2013-05-30 Mahmut Bilgic Synergistilly active combinations of roflumilast and carmoterol
CN103784443A (zh) * 2014-02-18 2014-05-14 青岛市城阳区人民医院 一种包含沙美特罗和罗氟司特的药物组合产品

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5795564A (en) * 1991-04-05 1998-08-18 Sepracor, Inc. Methods and compositions for treating pulmonary disorders using optically pure (R,R)-formoterol
ES2178015T3 (es) * 1996-11-11 2002-12-16 Sepracor Inc Procedimiento de preparacion de isomeros de formoterol opticamente puros.
CZ293871B6 (cs) * 1997-02-17 2004-08-18 Altanaápharmaáag Prostředky pro léčbu ARDS nebo IRDS obsahující @}cyklopropylmethoxyB@N@}@ŹQ@dichloro@pyridinylB@}difluoromethoxyBbenzamid a plicní surfaktant
JP2001513097A (ja) * 1997-02-28 2001-08-28 ビイク グルデン ロンベルク ヒエーミツシエ フアブリーク ゲゼルシヤフト ミツト ベシユレンクテル ハフツング Pde−抑制物質とアデニル酸シクラーゼ・アゴニストもしくはグアニル酸シクラーゼ・アゴニストとからなる相乗的組み合わせ組成物
US6624181B1 (en) * 1997-02-28 2003-09-23 Altana Pharma Ag Synergistic combination
MY126544A (en) * 1998-08-26 2006-10-31 Smithkline Beecham Corp Therapies for treating pulmonary diseases
US6303145B2 (en) * 1999-05-10 2001-10-16 Sepracor Inc. (S,R) formoterol methods and compositions
DE60043318D1 (de) * 1999-08-21 2010-01-14 Nycomed Gmbh Synergistische kombination von pumafentrine und salmeterol
GB0103630D0 (en) * 2001-02-14 2001-03-28 Glaxo Group Ltd Chemical compounds
DE60224172T2 (de) * 2001-03-22 2008-12-04 Glaxo Group Ltd., Greenford Formanilid-derivative als beta2-adrenorezeptor-agonisten
CN1302007C (zh) * 2001-04-30 2007-02-28 葛兰素集团有限公司 具有抗炎性的在17.α位上具有环酯基的雄甾烷的17.β.-硫代羧酸酯衍生物

Also Published As

Publication number Publication date
IS2576B (is) 2010-02-15
DE60321954D1 (de) 2008-08-14
UA83017C2 (uk) 2008-06-10
CY1110368T1 (el) 2015-04-29
ATE399544T1 (de) 2008-07-15
HRP20050580A2 (en) 2006-08-31
HK1081862A1 (en) 2006-05-26
DK1567140T3 (da) 2008-11-03
PL375632A1 (en) 2005-12-12
MA27538A1 (fr) 2005-09-01
PL214869B1 (pl) 2013-09-30
WO2004047828A1 (en) 2004-06-10
AU2003288169A1 (en) 2004-06-18
JP2006508993A (ja) 2006-03-16
HRP20050580B1 (hr) 2014-04-11
RS51082B (sr) 2010-10-31
ES2309374T3 (es) 2008-12-16
IL168307A (en) 2010-12-30
AU2003288169B2 (en) 2010-01-07
MXPA05005438A (es) 2005-08-03
US20060199865A1 (en) 2006-09-07
EA009990B1 (ru) 2008-04-28
SI1567140T1 (sl) 2008-12-31
NO20053023L (no) 2005-06-20
EA200500865A1 (ru) 2005-12-29
BR0316475A (pt) 2005-10-11
KR20050094810A (ko) 2005-09-28
CA2506956A1 (en) 2004-06-10
ME00488B (me) 2011-10-10
ZA200503307B (en) 2006-11-29
PT1567140E (pt) 2008-09-24
IS7899A (is) 2005-06-20
CN1713902A (zh) 2005-12-28
AU2003288169B8 (en) 2010-08-26
EP1567140B1 (en) 2008-07-02
NZ540658A (en) 2007-03-30
TNSN05130A1 (en) 2007-05-14
RS20050383A (en) 2007-08-03
CA2506956C (en) 2012-10-02
EP1567140A1 (en) 2005-08-31
NO334148B1 (no) 2013-12-16

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