DE60321954D1 - Synergistische zusammensetzung enthaltend roflumilast und (r,r)-formoterol - Google Patents

Synergistische zusammensetzung enthaltend roflumilast und (r,r)-formoterol

Info

Publication number
DE60321954D1
DE60321954D1 DE60321954T DE60321954T DE60321954D1 DE 60321954 D1 DE60321954 D1 DE 60321954D1 DE 60321954 T DE60321954 T DE 60321954T DE 60321954 T DE60321954 T DE 60321954T DE 60321954 D1 DE60321954 D1 DE 60321954D1
Authority
DE
Germany
Prior art keywords
formoterol
composition containing
synergistic composition
containing roflumilast
roflumilast
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE60321954T
Other languages
German (de)
English (en)
Inventor
Rolf Beume
Daniela Bundschuh
Degenhard Marx
Christian Weimar
Stefan-Lutz Wollin
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Takeda GmbH
Original Assignee
Nycomed GmbH
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Nycomed GmbH filed Critical Nycomed GmbH
Application granted granted Critical
Publication of DE60321954D1 publication Critical patent/DE60321954D1/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44Non condensed pyridines; Hydrogenated derivatives thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/16Amides, e.g. hydroxamic acids
    • A61K31/165Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide
    • A61K31/167Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide having the nitrogen of a carboxamide group directly attached to the aromatic ring, e.g. lidocaine, paracetamol
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • A61P11/06Antiasthmatics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • A61P11/08Bronchodilators

Landscapes

  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Pulmonology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Pain & Pain Management (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
DE60321954T 2002-11-27 2003-11-26 Synergistische zusammensetzung enthaltend roflumilast und (r,r)-formoterol Expired - Lifetime DE60321954D1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP02026504 2002-11-27
PCT/EP2003/013266 WO2004047828A1 (en) 2002-11-27 2003-11-26 Synergistic combination compresing roflumilas and (r.r) -formoterol

Publications (1)

Publication Number Publication Date
DE60321954D1 true DE60321954D1 (de) 2008-08-14

Family

ID=32338001

Family Applications (1)

Application Number Title Priority Date Filing Date
DE60321954T Expired - Lifetime DE60321954D1 (de) 2002-11-27 2003-11-26 Synergistische zusammensetzung enthaltend roflumilast und (r,r)-formoterol

Country Status (31)

Country Link
US (1) US20060199865A1 (enExample)
EP (1) EP1567140B1 (enExample)
JP (1) JP2006508993A (enExample)
KR (1) KR20050094810A (enExample)
CN (1) CN1713902A (enExample)
AT (1) ATE399544T1 (enExample)
AU (1) AU2003288169B8 (enExample)
BR (1) BR0316475A (enExample)
CA (1) CA2506956C (enExample)
CO (1) CO5690571A2 (enExample)
CY (1) CY1110368T1 (enExample)
DE (1) DE60321954D1 (enExample)
DK (1) DK1567140T3 (enExample)
EA (1) EA009990B1 (enExample)
ES (1) ES2309374T3 (enExample)
HR (1) HRP20050580B1 (enExample)
IL (1) IL168307A (enExample)
IS (1) IS2576B (enExample)
MA (1) MA27538A1 (enExample)
ME (1) ME00488B (enExample)
MX (1) MXPA05005438A (enExample)
NO (1) NO334148B1 (enExample)
NZ (1) NZ540658A (enExample)
PL (1) PL214869B1 (enExample)
PT (1) PT1567140E (enExample)
RS (1) RS51082B (enExample)
SI (1) SI1567140T1 (enExample)
TN (1) TNSN05130A1 (enExample)
UA (1) UA83017C2 (enExample)
WO (1) WO2004047828A1 (enExample)
ZA (1) ZA200503307B (enExample)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
MY140561A (en) 2002-02-20 2009-12-31 Nycomed Gmbh Dosage form containing pde 4 inhibitor as active ingredient
ES2335498T3 (es) 2003-03-10 2010-03-29 Nycomed Gmbh Nuevo proceso para la preparacion de reflumilast.
EP2258350B1 (en) 2005-03-16 2014-12-24 Takeda GmbH Taste masked dosage form containing roflumilast
WO2013077830A1 (en) * 2011-11-25 2013-05-30 Mahmut Bilgic Synergistilly active combinations of roflumilast and carmoterol
CN103784443A (zh) * 2014-02-18 2014-05-14 青岛市城阳区人民医院 一种包含沙美特罗和罗氟司特的药物组合产品

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5795564A (en) * 1991-04-05 1998-08-18 Sepracor, Inc. Methods and compositions for treating pulmonary disorders using optically pure (R,R)-formoterol
EP0938467B1 (en) * 1996-11-11 2002-06-12 Sepracor, Inc. Process for the preparation of optically pure isomers of formoterol
TR199901772T2 (enExample) * 1997-02-17 1999-09-21 Byk Gulden Lomberg Chemische Fabrik Gmbh
US6624181B1 (en) * 1997-02-28 2003-09-23 Altana Pharma Ag Synergistic combination
JP2001513097A (ja) * 1997-02-28 2001-08-28 ビイク グルデン ロンベルク ヒエーミツシエ フアブリーク ゲゼルシヤフト ミツト ベシユレンクテル ハフツング Pde−抑制物質とアデニル酸シクラーゼ・アゴニストもしくはグアニル酸シクラーゼ・アゴニストとからなる相乗的組み合わせ組成物
KR20010072931A (ko) * 1998-08-26 2001-07-31 스튜어트 알. 수터, 스티븐 베네티아너, 피터 존 기딩스 폐 질환 치료 요법
US6303145B2 (en) * 1999-05-10 2001-10-16 Sepracor Inc. (S,R) formoterol methods and compositions
CZ302882B6 (cs) * 1999-08-21 2012-01-04 Nycomed Gmbh Farmaceutický prostredek
GB0103630D0 (en) * 2001-02-14 2001-03-28 Glaxo Group Ltd Chemical compounds
US7045658B2 (en) * 2001-03-22 2006-05-16 Glaxo Group Limited Formailide derivatives as beta2-adrenoreceptor agonists
CA2445839A1 (en) * 2001-04-30 2002-11-07 Glaxo Group Limited Anti-inflammatory 17.beta.-carbothioate ester derivatives of androstane with a cyclic ester group in position 17.alpha

Also Published As

Publication number Publication date
CN1713902A (zh) 2005-12-28
IS7899A (is) 2005-06-20
EA200500865A1 (ru) 2005-12-29
DK1567140T3 (da) 2008-11-03
ZA200503307B (en) 2006-11-29
RS20050383A (sr) 2007-08-03
EP1567140A1 (en) 2005-08-31
IS2576B (is) 2010-02-15
IL168307A (en) 2010-12-30
KR20050094810A (ko) 2005-09-28
AU2003288169B2 (en) 2010-01-07
MA27538A1 (fr) 2005-09-01
AU2003288169A1 (en) 2004-06-18
TNSN05130A1 (en) 2007-05-14
PL375632A1 (en) 2005-12-12
HK1081862A1 (en) 2006-05-26
CY1110368T1 (el) 2015-04-29
CA2506956A1 (en) 2004-06-10
PT1567140E (pt) 2008-09-24
EP1567140B1 (en) 2008-07-02
HRP20050580A2 (en) 2006-08-31
ATE399544T1 (de) 2008-07-15
UA83017C2 (uk) 2008-06-10
NO334148B1 (no) 2013-12-16
AU2003288169B8 (en) 2010-08-26
ME00488B (me) 2011-10-10
MXPA05005438A (es) 2005-08-03
US20060199865A1 (en) 2006-09-07
NO20053023L (no) 2005-06-20
CA2506956C (en) 2012-10-02
HRP20050580B1 (hr) 2014-04-11
ES2309374T3 (es) 2008-12-16
EA009990B1 (ru) 2008-04-28
NZ540658A (en) 2007-03-30
JP2006508993A (ja) 2006-03-16
BR0316475A (pt) 2005-10-11
WO2004047828A1 (en) 2004-06-10
PL214869B1 (pl) 2013-09-30
CO5690571A2 (es) 2006-10-31
RS51082B (sr) 2010-10-31
SI1567140T1 (sl) 2008-12-31

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Legal Events

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