PT1526856E - Composição farmacêutica que compreende derivados do estretol para ser utilizada no tratamento do cancro - Google Patents

Composição farmacêutica que compreende derivados do estretol para ser utilizada no tratamento do cancro Download PDF

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Publication number
PT1526856E
PT1526856E PT03764245T PT03764245T PT1526856E PT 1526856 E PT1526856 E PT 1526856E PT 03764245 T PT03764245 T PT 03764245T PT 03764245 T PT03764245 T PT 03764245T PT 1526856 E PT1526856 E PT 1526856E
Authority
PT
Portugal
Prior art keywords
pharmaceutical composition
cancer therapy
estetrol
derivatives
estetrol derivatives
Prior art date
Application number
PT03764245T
Other languages
English (en)
Inventor
Herman Jan Tijmen Coelingh Bennink
Evert Johannes Bunschoten
Original Assignee
Pantarhei Bioscience Bv
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pantarhei Bioscience Bv filed Critical Pantarhei Bioscience Bv
Publication of PT1526856E publication Critical patent/PT1526856E/pt

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/4196—1,2,4-Triazoles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/565—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
PT03764245T 2002-07-12 2003-07-11 Composição farmacêutica que compreende derivados do estretol para ser utilizada no tratamento do cancro PT1526856E (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP02077812 2002-07-12
EP03075435 2003-02-14

Publications (1)

Publication Number Publication Date
PT1526856E true PT1526856E (pt) 2008-04-11

Family

ID=30116907

Family Applications (1)

Application Number Title Priority Date Filing Date
PT03764245T PT1526856E (pt) 2002-07-12 2003-07-11 Composição farmacêutica que compreende derivados do estretol para ser utilizada no tratamento do cancro

Country Status (13)

Country Link
US (2) US9034854B2 (pt)
EP (1) EP1526856B1 (pt)
CN (1) CN100374116C (pt)
AT (1) ATE382356T1 (pt)
AU (1) AU2003253506A1 (pt)
CA (1) CA2492287C (pt)
CY (1) CY1107906T1 (pt)
DE (1) DE60318447T2 (pt)
DK (1) DK1526856T3 (pt)
ES (1) ES2299730T3 (pt)
PT (1) PT1526856E (pt)
SI (1) SI1526856T1 (pt)
WO (1) WO2004006936A1 (pt)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2299730T3 (es) * 2002-07-12 2008-06-01 Pantarhei Bioscience B.V. Composicion farmaceutica que comprende derivados de estetrol para el uso en la terapia del cancer.
DE102007032468A1 (de) * 2007-07-10 2009-01-15 Brätter, Christian, Dr. Transdermale Therapeutische Systeme, welche den Wirkstoff Anastrozol enthalten
CA2835979C (en) 2011-06-01 2018-05-01 Estetra S.A. Process for the production of estetrol intermediates
PT2714710T (pt) 2011-06-01 2016-07-12 Estetra Sprl Processo para a produção de intermediários de estetrol
EP2383279A1 (en) 2011-07-19 2011-11-02 Pantarhei Bioscience B.V. Process for the preparation of estetrol
WO2013034780A2 (en) 2012-12-20 2013-03-14 Crystal Pharma, S.A.U. Process for the preparation of estetrol and related compounds
JP6254289B2 (ja) 2013-09-18 2017-12-27 クリスタル ファルマ、エセ、ア、ウＣｒｙｓｔａｌ Ｐｈａｒｍａ，Ｓ．Ａ．Ｕ． エステトロールの製造プロセス
EP3310346B1 (en) 2015-06-18 2021-03-24 Estetra SPRL Orodispersible tablet containing estetrol
SI3310333T1 (sl) 2015-06-18 2020-08-31 Estetra Sprl Orodisperzibilna enota odmerka, ki vsebuje komponento estetrola
KR102664563B1 (ko) 2015-06-18 2024-05-09 에스테트라, 소시에떼 아 레스폰서빌리떼 리미떼 에스테트롤 성분을 함유하는 구강분해성 투여 단위
CA2988485A1 (en) * 2015-06-18 2016-12-22 Mithra Pharmaceuticals S.A. Orodispersible tablet containing estetrol
CA3178291A1 (en) 2016-08-05 2018-04-12 Estetra Srl Method for the management of dysmenorrhea and menstrual pain
TWI801561B (zh) 2018-04-19 2023-05-11 比利時商依思特拉私人有限責任公司 化合物及其用於緩解絕經相關症狀的用途
JOP20200260A1 (ar) 2018-04-19 2019-10-19 Estetra Sprl مركبات واستخداماتها للتخفيف من الأعراض المصاحبة لانقطاع الطمث
CN112351782A (zh) * 2018-05-02 2021-02-09 埃斯特拉私人有限责任公司 晚期雌激素受体阳性乳腺癌的治疗
HU231240B1 (hu) 2019-09-03 2022-04-28 Richter Gedeon Nyrt. Ipari eljárás nagytisztaságú ösztetrol hatóanyag előállítására

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SI1556058T1 (sl) * 2002-10-23 2008-02-29 Pantarhei Bioscience Bv Farmacevtski sestavki, ki obsegajo estetrolne derivate, za uporabo pri zdravljenju raka
PT1624878E (pt) * 2003-05-22 2007-01-31 Pantarhei Bioscience Bv Utilização de composições que compreendem um componente estrogénico para o tratamento e prevenção da dor musculoesquelética

Also Published As

Publication number Publication date
US20060063723A1 (en) 2006-03-23
SI1526856T1 (sl) 2008-04-30
WO2004006936A1 (en) 2004-01-22
ATE382356T1 (de) 2008-01-15
CN100374116C (zh) 2008-03-12
DE60318447D1 (de) 2008-02-14
CY1107906T1 (el) 2013-09-04
DK1526856T3 (da) 2008-03-10
US20150133413A1 (en) 2015-05-14
CA2492287A1 (en) 2004-01-22
ES2299730T3 (es) 2008-06-01
WO2004006936A8 (en) 2005-03-03
CN1681513A (zh) 2005-10-12
EP1526856B1 (en) 2008-01-02
EP1526856A1 (en) 2005-05-04
DE60318447T2 (de) 2009-01-02
US10201611B2 (en) 2019-02-12
AU2003253506A1 (en) 2004-02-02
US9034854B2 (en) 2015-05-19
CA2492287C (en) 2011-12-13

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