PT1520858E - Processo para produzir péptido de açúcar com cadeia de açúcar asparagina e o péptido de açúcar - Google Patents
Processo para produzir péptido de açúcar com cadeia de açúcar asparagina e o péptido de açúcar Download PDFInfo
- Publication number
- PT1520858E PT1520858E PT37412038T PT03741203T PT1520858E PT 1520858 E PT1520858 E PT 1520858E PT 37412038 T PT37412038 T PT 37412038T PT 03741203 T PT03741203 T PT 03741203T PT 1520858 E PT1520858 E PT 1520858E
- Authority
- PT
- Portugal
- Prior art keywords
- asparagine
- linked oligosaccharides
- preparing glycopeptides
- glycopeptides
- preparing
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
- C07K1/06—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length using protecting groups or activating agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
- C07K1/107—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length by chemical modification of precursor peptides
- C07K1/1072—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length by chemical modification of precursor peptides by covalent attachment of residues or functional groups
- C07K1/1077—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length by chemical modification of precursor peptides by covalent attachment of residues or functional groups by covalent attachment of residues other than amino acids or peptide residues, e.g. sugars, polyols, fatty acids
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
- C07K5/10—Tetrapeptides
- C07K5/1002—Tetrapeptides with the first amino acid being neutral
- C07K5/1005—Tetrapeptides with the first amino acid being neutral and aliphatic
- C07K5/1008—Tetrapeptides with the first amino acid being neutral and aliphatic the side chain containing 0 or 1 carbon atoms, i.e. Gly, Ala
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K9/00—Peptides having up to 20 amino acids, containing saccharide radicals and having a fully defined sequence; Derivatives thereof
- C07K9/001—Peptides having up to 20 amino acids, containing saccharide radicals and having a fully defined sequence; Derivatives thereof the peptide sequence having less than 12 amino acids and not being part of a ring structure
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08B—POLYSACCHARIDES; DERIVATIVES THEREOF
- C08B37/00—Preparation of polysaccharides not provided for in groups C08B1/00 - C08B35/00; Derivatives thereof
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
- Y02P20/00—Technologies relating to chemical industry
- Y02P20/50—Improvements relating to the production of bulk chemicals
- Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Molecular Biology (AREA)
- Biochemistry (AREA)
- Genetics & Genomics (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Biophysics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Analytical Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Polymers & Plastics (AREA)
- General Chemical & Material Sciences (AREA)
- Materials Engineering (AREA)
- Peptides Or Proteins (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Polysaccharides And Polysaccharide Derivatives (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP2002196821 | 2002-07-05 | ||
JP2002349166 | 2002-11-29 |
Publications (1)
Publication Number | Publication Date |
---|---|
PT1520858E true PT1520858E (pt) | 2014-02-04 |
Family
ID=30117389
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PT37412038T PT1520858E (pt) | 2002-07-05 | 2003-07-04 | Processo para produzir péptido de açúcar com cadeia de açúcar asparagina e o péptido de açúcar |
Country Status (12)
Country | Link |
---|---|
US (3) | US7943763B2 (pt) |
EP (2) | EP2412720B1 (pt) |
JP (1) | JP4119428B2 (pt) |
KR (1) | KR100634664B1 (pt) |
CN (3) | CN1665832B (pt) |
AU (1) | AU2003281360B2 (pt) |
CA (2) | CA2822657C (pt) |
DK (2) | DK2412720T3 (pt) |
ES (1) | ES2449495T3 (pt) |
PT (1) | PT1520858E (pt) |
TW (1) | TWI263643B (pt) |
WO (1) | WO2004005330A1 (pt) |
Families Citing this family (26)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JP2006022191A (ja) * | 2004-07-07 | 2006-01-26 | Yasuhiro Kajiwara | 3分岐型糖鎖アスパラギン誘導体、該糖鎖アスパラギン、該糖鎖およびそれらの製造方法 |
EP2000474B1 (en) | 2006-03-29 | 2017-11-01 | Glytech, Inc. | Method for production of peptide thioester compound |
CN102015761A (zh) | 2007-06-19 | 2011-04-13 | 大塚化学株式会社 | 附加糖链的glp-1肽 |
CN102850442B (zh) * | 2007-07-31 | 2014-07-30 | 株式会社糖锁工学研究所 | 糖肽 |
JP5272395B2 (ja) * | 2007-12-12 | 2013-08-28 | セントラル硝子株式会社 | 4−デオキシ−4−フルオロ−d−グルコース誘導体の製造方法 |
AU2009261441B2 (en) | 2008-06-17 | 2013-01-10 | Glytech, Inc. | Oligosaccharide chain added glp-1 peptide |
HUE037238T2 (hu) * | 2008-08-19 | 2018-08-28 | Glytech Inc | Glikoprotein elõállítási eljárás és screening eljárás |
TW201031749A (en) * | 2009-02-10 | 2010-09-01 | Otsuka Chemical Co Ltd | IgG-Fc fragment and method for manufacturing the same |
JPWO2011007747A1 (ja) | 2009-07-16 | 2012-12-27 | 株式会社糖鎖工学研究所 | 糖鎖付加ailim細胞外ドメイン及びその製造方法 |
EP2495255A4 (en) | 2009-10-30 | 2013-05-15 | Otsuka Chemical Co Ltd | GLYCOSYLATED FORM OF AN ANTIGENIC GLP-1 ANALOG |
SG193377A1 (en) | 2011-03-10 | 2013-10-30 | Glytech Inc | Method for producing glycopeptide having sialyl sugar chain, sialyl sugar chain-added amino acid derivative to be used in same, and glycopeptide |
US9422357B2 (en) | 2011-09-04 | 2016-08-23 | Glytech, Inc. | Glycosylated polypeptide and drug composition containing said polypeptide |
CN106146649B (zh) | 2011-09-04 | 2020-09-01 | 株式会社糖锁工学研究所 | 附加糖链的多肽和含有该多肽的医药组合物 |
IN2014CN02854A (pt) | 2011-09-26 | 2015-07-03 | Glytech Inc | |
IN2014CN02982A (pt) | 2011-10-01 | 2015-07-03 | Glytech Inc | |
WO2014080730A1 (ja) | 2012-11-22 | 2014-05-30 | 株式会社糖鎖工学研究所 | 糖鎖付加リンカー、糖鎖付加リンカー部分と生理活性物質部分とを含む化合物またはその塩、及びそれらの製造方法 |
CN104936613B (zh) | 2012-11-30 | 2018-05-22 | 株式会社糖锁工学研究所 | 糖链加成连接子、含有糖链加成连接子与生理活性物质的化合物或其盐、以及其制造方法 |
SG11201507769SA (en) | 2013-03-29 | 2015-10-29 | Glytech Inc | Polypeptide having sialylated sugar chains attached thereto |
SG11201508032RA (en) | 2013-03-30 | 2015-10-29 | Glytech Inc | (sugar chain)-polypeptide complex |
EP3068891A1 (en) | 2013-11-13 | 2016-09-21 | Aequus Biopharma Inc. | Engineered glycoproteins and uses thereof |
WO2015123756A1 (en) * | 2014-02-18 | 2015-08-27 | The University Of British Columbia | Hydrolysis resistant sialic acid derivatives and methods for their use |
WO2015145797A1 (ja) * | 2014-03-28 | 2015-10-01 | 大塚化学株式会社 | 止血用医薬組成物 |
CN104020216B (zh) * | 2014-06-19 | 2017-02-15 | 苏州中科纳泰生物科技有限公司 | 一种两端标记相对定量分析糖链的方法 |
DK3318575T3 (da) * | 2015-06-30 | 2021-04-12 | Glytech Inc | Albumin-sukkerkædekompleks |
JP6852397B2 (ja) * | 2016-12-28 | 2021-03-31 | 株式会社島津製作所 | 分析用試料の調製方法および分析方法 |
US20210060169A1 (en) | 2017-12-27 | 2021-03-04 | Kyowa Kirin Co., Ltd. | Il-2 variant |
Family Cites Families (12)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5079353A (en) * | 1987-12-02 | 1992-01-07 | Chembiomed, Ltd. | Sialic acid glycosides, antigens, immunoadsorbents, and methods for their preparation |
WO1991009975A1 (en) | 1989-12-29 | 1991-07-11 | Symex Corp. | Chromogenic 7- or 8-position modified n-acetylneuraminic acid substrates and methods for diagnosing human influenza therewith |
HUT69613A (en) * | 1992-03-12 | 1995-09-28 | Lilly Co Eli | Method for producing carbohydrates |
US5324483B1 (en) | 1992-10-08 | 1996-09-24 | Warner Lambert Co | Apparatus for multiple simultaneous synthesis |
EP0711766B1 (en) | 1994-05-27 | 2000-02-16 | Daikin Industries, Limited | 7-fluoro-2, 3-didehydrosialic acid and intermediate for synthesis thereof |
US5843713A (en) | 1994-11-01 | 1998-12-01 | Kirin Beer Kabushiki Kaisha | Peptide sequence that forms mucin sugar chain and technique for modifying protein to be linked with mucin sugar chain |
JP3684028B2 (ja) * | 1996-07-16 | 2005-08-17 | 株式会社東芝 | 原子炉格納容器 |
JPH10259198A (ja) | 1996-12-24 | 1998-09-29 | Sankyo Co Ltd | 連結したt細胞エピトープとその用途 |
JPH11255807A (ja) | 1998-03-13 | 1999-09-21 | Noguchi Inst | 糖鎖アスパラギン活性エステル誘導体とその合成中間体 |
EP1124946B1 (en) * | 1998-10-30 | 2007-06-20 | Novozymes A/S | Glycosylated proteins having reduced allergenicity |
WO2003008431A1 (fr) | 2001-06-19 | 2003-01-30 | Otsuka Chemical Co.,Ltd. | Methode de production d'un derive d'asparagine de chaines des sucres |
US20030229013A1 (en) * | 2001-12-07 | 2003-12-11 | Shih-Kwang Wu | Solid phase method for synthesis peptide-spacer-lipid conjugates, conjugates synthesized thereby and targeted liposomes containing the same |
-
2003
- 2003-07-02 US US10/519,983 patent/US7943763B2/en not_active Expired - Lifetime
- 2003-07-04 DK DK10179510.2T patent/DK2412720T3/en active
- 2003-07-04 WO PCT/JP2003/008551 patent/WO2004005330A1/ja active Application Filing
- 2003-07-04 AU AU2003281360A patent/AU2003281360B2/en not_active Expired
- 2003-07-04 CN CN03815950.3A patent/CN1665832B/zh not_active Expired - Fee Related
- 2003-07-04 JP JP2004519274A patent/JP4119428B2/ja not_active Expired - Fee Related
- 2003-07-04 CN CN038159503A patent/CN1665832A/zh active Granted
- 2003-07-04 KR KR1020057000108A patent/KR100634664B1/ko active IP Right Grant
- 2003-07-04 TW TW092118290A patent/TWI263643B/zh not_active IP Right Cessation
- 2003-07-04 CA CA2822657A patent/CA2822657C/en not_active Expired - Lifetime
- 2003-07-04 EP EP10179510.2A patent/EP2412720B1/en not_active Expired - Lifetime
- 2003-07-04 CA CA2491594A patent/CA2491594C/en not_active Expired - Lifetime
- 2003-07-04 CN CN2011101153138A patent/CN102241743A/zh active Pending
- 2003-07-04 DK DK03741203.8T patent/DK1520858T3/en active
- 2003-07-04 ES ES03741203.8T patent/ES2449495T3/es not_active Expired - Lifetime
- 2003-07-04 EP EP03741203.8A patent/EP1520858B1/en not_active Expired - Lifetime
- 2003-07-04 PT PT37412038T patent/PT1520858E/pt unknown
-
2009
- 2009-04-16 US US12/385,711 patent/US8063202B2/en not_active Expired - Fee Related
-
2011
- 2011-10-14 US US13/273,786 patent/US8399656B2/en not_active Expired - Lifetime
Also Published As
Publication number | Publication date |
---|---|
US8399656B2 (en) | 2013-03-19 |
AU2003281360A1 (en) | 2004-01-23 |
US20090234095A1 (en) | 2009-09-17 |
CA2822657A1 (en) | 2004-01-15 |
EP2412720A3 (en) | 2012-06-13 |
WO2004005330A1 (ja) | 2004-01-15 |
DK2412720T3 (en) | 2016-01-25 |
US8063202B2 (en) | 2011-11-22 |
EP1520858A4 (en) | 2007-12-26 |
EP1520858A1 (en) | 2005-04-06 |
CA2491594C (en) | 2013-10-22 |
JP4119428B2 (ja) | 2008-07-16 |
CA2491594A1 (en) | 2004-01-15 |
TW200406422A (en) | 2004-05-01 |
CN102241743A (zh) | 2011-11-16 |
ES2449495T3 (es) | 2014-03-20 |
US20050222382A1 (en) | 2005-10-06 |
CN1665832A (zh) | 2005-09-07 |
KR100634664B1 (ko) | 2006-10-16 |
KR20050016959A (ko) | 2005-02-21 |
EP1520858B1 (en) | 2013-11-27 |
US7943763B2 (en) | 2011-05-17 |
AU2003281360B2 (en) | 2007-10-11 |
TWI263643B (en) | 2006-10-11 |
EP2412720B1 (en) | 2015-10-21 |
US20120035345A1 (en) | 2012-02-09 |
CA2822657C (en) | 2015-11-17 |
DK1520858T3 (en) | 2014-03-03 |
EP2412720A2 (en) | 2012-02-01 |
JPWO2004005330A1 (ja) | 2005-11-04 |
CN1665832B (zh) | 2014-04-02 |
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