PT1520858E - Processo para produzir péptido de açúcar com cadeia de açúcar asparagina e o péptido de açúcar - Google Patents

Processo para produzir péptido de açúcar com cadeia de açúcar asparagina e o péptido de açúcar Download PDF

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Publication number
PT1520858E
PT1520858E PT37412038T PT03741203T PT1520858E PT 1520858 E PT1520858 E PT 1520858E PT 37412038 T PT37412038 T PT 37412038T PT 03741203 T PT03741203 T PT 03741203T PT 1520858 E PT1520858 E PT 1520858E
Authority
PT
Portugal
Prior art keywords
asparagine
linked oligosaccharides
preparing glycopeptides
glycopeptides
preparing
Prior art date
Application number
PT37412038T
Other languages
English (en)
Inventor
Yasuhiro Kajihara
Original Assignee
Yasuhiro Kajihara
Glytech Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Yasuhiro Kajihara, Glytech Inc filed Critical Yasuhiro Kajihara
Publication of PT1520858E publication Critical patent/PT1520858E/pt

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Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K1/00General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/06General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length using protecting groups or activating agents
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K1/00General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/107General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length by chemical modification of precursor peptides
    • C07K1/1072General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length by chemical modification of precursor peptides by covalent attachment of residues or functional groups
    • C07K1/1077General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length by chemical modification of precursor peptides by covalent attachment of residues or functional groups by covalent attachment of residues other than amino acids or peptide residues, e.g. sugars, polyols, fatty acids
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K5/00Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/10Tetrapeptides
    • C07K5/1002Tetrapeptides with the first amino acid being neutral
    • C07K5/1005Tetrapeptides with the first amino acid being neutral and aliphatic
    • C07K5/1008Tetrapeptides with the first amino acid being neutral and aliphatic the side chain containing 0 or 1 carbon atoms, i.e. Gly, Ala
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K9/00Peptides having up to 20 amino acids, containing saccharide radicals and having a fully defined sequence; Derivatives thereof
    • C07K9/001Peptides having up to 20 amino acids, containing saccharide radicals and having a fully defined sequence; Derivatives thereof the peptide sequence having less than 12 amino acids and not being part of a ring structure
    • CCHEMISTRY; METALLURGY
    • C08ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08BPOLYSACCHARIDES; DERIVATIVES THEREOF
    • C08B37/00Preparation of polysaccharides not provided for in groups C08B1/00 - C08B35/00; Derivatives thereof
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02ATECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02PCLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00Technologies relating to chemical industry
    • Y02P20/50Improvements relating to the production of bulk chemicals
    • Y02P20/55Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Genetics & Genomics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biophysics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Analytical Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Polymers & Plastics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Materials Engineering (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Polysaccharides And Polysaccharide Derivatives (AREA)
PT37412038T 2002-07-05 2003-07-04 Processo para produzir péptido de açúcar com cadeia de açúcar asparagina e o péptido de açúcar PT1520858E (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP2002196821 2002-07-05
JP2002349166 2002-11-29

Publications (1)

Publication Number Publication Date
PT1520858E true PT1520858E (pt) 2014-02-04

Family

ID=30117389

Family Applications (1)

Application Number Title Priority Date Filing Date
PT37412038T PT1520858E (pt) 2002-07-05 2003-07-04 Processo para produzir péptido de açúcar com cadeia de açúcar asparagina e o péptido de açúcar

Country Status (12)

Country Link
US (3) US7943763B2 (pt)
EP (2) EP2412720B1 (pt)
JP (1) JP4119428B2 (pt)
KR (1) KR100634664B1 (pt)
CN (3) CN1665832B (pt)
AU (1) AU2003281360B2 (pt)
CA (2) CA2822657C (pt)
DK (2) DK2412720T3 (pt)
ES (1) ES2449495T3 (pt)
PT (1) PT1520858E (pt)
TW (1) TWI263643B (pt)
WO (1) WO2004005330A1 (pt)

Families Citing this family (26)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2006022191A (ja) * 2004-07-07 2006-01-26 Yasuhiro Kajiwara 3分岐型糖鎖アスパラギン誘導体、該糖鎖アスパラギン、該糖鎖およびそれらの製造方法
EP2000474B1 (en) 2006-03-29 2017-11-01 Glytech, Inc. Method for production of peptide thioester compound
CN102015761A (zh) 2007-06-19 2011-04-13 大塚化学株式会社 附加糖链的glp-1肽
CN102850442B (zh) * 2007-07-31 2014-07-30 株式会社糖锁工学研究所 糖肽
JP5272395B2 (ja) * 2007-12-12 2013-08-28 セントラル硝子株式会社 4−デオキシ−4−フルオロ−d−グルコース誘導体の製造方法
AU2009261441B2 (en) 2008-06-17 2013-01-10 Glytech, Inc. Oligosaccharide chain added glp-1 peptide
HUE037238T2 (hu) * 2008-08-19 2018-08-28 Glytech Inc Glikoprotein elõállítási eljárás és screening eljárás
TW201031749A (en) * 2009-02-10 2010-09-01 Otsuka Chemical Co Ltd IgG-Fc fragment and method for manufacturing the same
JPWO2011007747A1 (ja) 2009-07-16 2012-12-27 株式会社糖鎖工学研究所 糖鎖付加ailim細胞外ドメイン及びその製造方法
EP2495255A4 (en) 2009-10-30 2013-05-15 Otsuka Chemical Co Ltd GLYCOSYLATED FORM OF AN ANTIGENIC GLP-1 ANALOG
SG193377A1 (en) 2011-03-10 2013-10-30 Glytech Inc Method for producing glycopeptide having sialyl sugar chain, sialyl sugar chain-added amino acid derivative to be used in same, and glycopeptide
US9422357B2 (en) 2011-09-04 2016-08-23 Glytech, Inc. Glycosylated polypeptide and drug composition containing said polypeptide
CN106146649B (zh) 2011-09-04 2020-09-01 株式会社糖锁工学研究所 附加糖链的多肽和含有该多肽的医药组合物
IN2014CN02854A (pt) 2011-09-26 2015-07-03 Glytech Inc
IN2014CN02982A (pt) 2011-10-01 2015-07-03 Glytech Inc
WO2014080730A1 (ja) 2012-11-22 2014-05-30 株式会社糖鎖工学研究所 糖鎖付加リンカー、糖鎖付加リンカー部分と生理活性物質部分とを含む化合物またはその塩、及びそれらの製造方法
CN104936613B (zh) 2012-11-30 2018-05-22 株式会社糖锁工学研究所 糖链加成连接子、含有糖链加成连接子与生理活性物质的化合物或其盐、以及其制造方法
SG11201507769SA (en) 2013-03-29 2015-10-29 Glytech Inc Polypeptide having sialylated sugar chains attached thereto
SG11201508032RA (en) 2013-03-30 2015-10-29 Glytech Inc (sugar chain)-polypeptide complex
EP3068891A1 (en) 2013-11-13 2016-09-21 Aequus Biopharma Inc. Engineered glycoproteins and uses thereof
WO2015123756A1 (en) * 2014-02-18 2015-08-27 The University Of British Columbia Hydrolysis resistant sialic acid derivatives and methods for their use
WO2015145797A1 (ja) * 2014-03-28 2015-10-01 大塚化学株式会社 止血用医薬組成物
CN104020216B (zh) * 2014-06-19 2017-02-15 苏州中科纳泰生物科技有限公司 一种两端标记相对定量分析糖链的方法
DK3318575T3 (da) * 2015-06-30 2021-04-12 Glytech Inc Albumin-sukkerkædekompleks
JP6852397B2 (ja) * 2016-12-28 2021-03-31 株式会社島津製作所 分析用試料の調製方法および分析方法
US20210060169A1 (en) 2017-12-27 2021-03-04 Kyowa Kirin Co., Ltd. Il-2 variant

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5079353A (en) * 1987-12-02 1992-01-07 Chembiomed, Ltd. Sialic acid glycosides, antigens, immunoadsorbents, and methods for their preparation
WO1991009975A1 (en) 1989-12-29 1991-07-11 Symex Corp. Chromogenic 7- or 8-position modified n-acetylneuraminic acid substrates and methods for diagnosing human influenza therewith
HUT69613A (en) * 1992-03-12 1995-09-28 Lilly Co Eli Method for producing carbohydrates
US5324483B1 (en) 1992-10-08 1996-09-24 Warner Lambert Co Apparatus for multiple simultaneous synthesis
EP0711766B1 (en) 1994-05-27 2000-02-16 Daikin Industries, Limited 7-fluoro-2, 3-didehydrosialic acid and intermediate for synthesis thereof
US5843713A (en) 1994-11-01 1998-12-01 Kirin Beer Kabushiki Kaisha Peptide sequence that forms mucin sugar chain and technique for modifying protein to be linked with mucin sugar chain
JP3684028B2 (ja) * 1996-07-16 2005-08-17 株式会社東芝 原子炉格納容器
JPH10259198A (ja) 1996-12-24 1998-09-29 Sankyo Co Ltd 連結したt細胞エピトープとその用途
JPH11255807A (ja) 1998-03-13 1999-09-21 Noguchi Inst 糖鎖アスパラギン活性エステル誘導体とその合成中間体
EP1124946B1 (en) * 1998-10-30 2007-06-20 Novozymes A/S Glycosylated proteins having reduced allergenicity
WO2003008431A1 (fr) 2001-06-19 2003-01-30 Otsuka Chemical Co.,Ltd. Methode de production d'un derive d'asparagine de chaines des sucres
US20030229013A1 (en) * 2001-12-07 2003-12-11 Shih-Kwang Wu Solid phase method for synthesis peptide-spacer-lipid conjugates, conjugates synthesized thereby and targeted liposomes containing the same

Also Published As

Publication number Publication date
US8399656B2 (en) 2013-03-19
AU2003281360A1 (en) 2004-01-23
US20090234095A1 (en) 2009-09-17
CA2822657A1 (en) 2004-01-15
EP2412720A3 (en) 2012-06-13
WO2004005330A1 (ja) 2004-01-15
DK2412720T3 (en) 2016-01-25
US8063202B2 (en) 2011-11-22
EP1520858A4 (en) 2007-12-26
EP1520858A1 (en) 2005-04-06
CA2491594C (en) 2013-10-22
JP4119428B2 (ja) 2008-07-16
CA2491594A1 (en) 2004-01-15
TW200406422A (en) 2004-05-01
CN102241743A (zh) 2011-11-16
ES2449495T3 (es) 2014-03-20
US20050222382A1 (en) 2005-10-06
CN1665832A (zh) 2005-09-07
KR100634664B1 (ko) 2006-10-16
KR20050016959A (ko) 2005-02-21
EP1520858B1 (en) 2013-11-27
US7943763B2 (en) 2011-05-17
AU2003281360B2 (en) 2007-10-11
TWI263643B (en) 2006-10-11
EP2412720B1 (en) 2015-10-21
US20120035345A1 (en) 2012-02-09
CA2822657C (en) 2015-11-17
DK1520858T3 (en) 2014-03-03
EP2412720A2 (en) 2012-02-01
JPWO2004005330A1 (ja) 2005-11-04
CN1665832B (zh) 2014-04-02

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