PT1487424E - 4-(4-metilpiperazin-1-ilmetil)-n-[4-metil-3-(4-piridin-3-il)pirimidin-2-il-amino)fenil]-benzamida para o tratamento doenças mediadas por ang ii - Google Patents
4-(4-metilpiperazin-1-ilmetil)-n-[4-metil-3-(4-piridin-3-il)pirimidin-2-il-amino)fenil]-benzamida para o tratamento doenças mediadas por ang ii Download PDFInfo
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- PT1487424E PT1487424E PT03727265T PT03727265T PT1487424E PT 1487424 E PT1487424 E PT 1487424E PT 03727265 T PT03727265 T PT 03727265T PT 03727265 T PT03727265 T PT 03727265T PT 1487424 E PT1487424 E PT 1487424E
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- hypertension
- combination
- methyl
- hypertrophy
- angiotensin
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- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Urology & Nephrology (AREA)
- Hospice & Palliative Care (AREA)
- Vascular Medicine (AREA)
- Pulmonology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB0206216A GB0206216D0 (en) | 2002-03-15 | 2002-03-15 | Organic compounds |
| GB0206217A GB0206217D0 (en) | 2002-03-15 | 2002-03-15 | Organic compounds |
| GB0217505A GB0217505D0 (en) | 2002-07-29 | 2002-07-29 | Organic compounds |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| PT1487424E true PT1487424E (pt) | 2007-01-31 |
Family
ID=28045959
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PT03727265T PT1487424E (pt) | 2002-03-15 | 2003-03-14 | 4-(4-metilpiperazin-1-ilmetil)-n-[4-metil-3-(4-piridin-3-il)pirimidin-2-il-amino)fenil]-benzamida para o tratamento doenças mediadas por ang ii |
Country Status (11)
| Country | Link |
|---|---|
| US (1) | US20050124624A1 (https=) |
| EP (1) | EP1487424B1 (https=) |
| JP (1) | JP2005527523A (https=) |
| AT (1) | ATE339197T1 (https=) |
| AU (1) | AU2003233946A1 (https=) |
| CY (1) | CY1105839T1 (https=) |
| DE (1) | DE60308337T2 (https=) |
| DK (1) | DK1487424T3 (https=) |
| ES (1) | ES2274234T3 (https=) |
| PT (1) | PT1487424E (https=) |
| WO (1) | WO2003077892A2 (https=) |
Families Citing this family (18)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20060154936A1 (en) * | 2002-10-25 | 2006-07-13 | Lasky Joseph A | Use of n-'5-'4-(4-methylpiperaziomethyl)-benzoylamido!-2-methylphenyl!-4-(3-pyridyl)2-pyridine-amine for the treatment of pulmonary hypertension |
| US20050192314A1 (en) | 2003-11-13 | 2005-09-01 | Ambit Biosciences Corporation | Urea derivatives as C-kit modulators |
| CA2552759A1 (en) * | 2004-01-22 | 2005-08-04 | Novartis Ag | Combination of organic compounds |
| GB0401761D0 (en) * | 2004-01-27 | 2004-03-03 | Novartis Ag | Organic compounds |
| AR047530A1 (es) * | 2004-02-04 | 2006-01-25 | Novartis Ag | Formas de sal de 4-(4-metilpiperazin-1-ilmetil)-n-(4-metil-3-(4-piridin-3-il)pirimidin-2-ilamino)fenil)-benzamida |
| MY148074A (en) * | 2005-05-10 | 2013-02-28 | Novartis Ag | Pharmaceutical compositions comprising imatinib and a release retardant |
| EP1741432A1 (de) * | 2005-07-07 | 2007-01-10 | Universitätsklinikum Freiburg | Tyrosinkinase-Inhibitor Imatinib zur Behandlung von Bluthochdruck |
| DE102005042544A1 (de) * | 2005-09-07 | 2007-03-08 | Ernst-Moritz-Arndt-Universität | Beeinflussung des kardialen Fc-Rezeptors zur Behandlung der dilatativen Kardiomyopathie |
| US20090304625A1 (en) * | 2006-01-18 | 2009-12-10 | Ahsan Husain | Modulators of cardiac cell hypertrophy and hyperplasia |
| EP1996582A2 (en) * | 2006-03-13 | 2008-12-03 | Encysive Pharmaceuticals, Inc | Polymorphs of n-(4-chloro-3-methyl-5-isoxazolyl)2-ý2-methyl-4,5-(methylenedioxy) phenylacetyl¨thiophene-3-sulfonamide, sodium salt |
| MX2008011842A (es) * | 2006-03-13 | 2008-10-02 | Encysive Pharmaceuticals Inc | Procedimientos y composiciones para el tratamiento de insuficiencia cardiaca diastolica. |
| CA2662265A1 (en) * | 2006-09-01 | 2008-03-06 | Teva Pharmaceutical Industries Ltd. | Imatinib compositions |
| TW201006823A (en) * | 2008-07-14 | 2010-02-16 | Novartis Ag | Use of pyrimidylaminobenzamide derivatives for the treatment of fibrosis |
| US20220143049A1 (en) | 2019-03-21 | 2022-05-12 | Onxeo | A dbait molecule in combination with kinase inhibitor for the treatment of cancer |
| WO2020245208A1 (en) | 2019-06-04 | 2020-12-10 | INSERM (Institut National de la Santé et de la Recherche Médicale) | Use of cd9 as a biomarker and as a biotarget in glomerulonephritis or glomerulosclerosis |
| EP4054579A1 (en) | 2019-11-08 | 2022-09-14 | Institut National de la Santé et de la Recherche Médicale (INSERM) | Methods for the treatment of cancers that have acquired resistance to kinase inhibitors |
| WO2021148581A1 (en) | 2020-01-22 | 2021-07-29 | Onxeo | Novel dbait molecule and its use |
| CN121712504A (zh) * | 2023-07-27 | 2026-03-20 | 矿物疗法公司 | 用洛伦司他及两种或更多种降压药的组合治疗高血压的方法 |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5521184A (en) * | 1992-04-03 | 1996-05-28 | Ciba-Geigy Corporation | Pyrimidine derivatives and processes for the preparation thereof |
| US20010051631A1 (en) * | 1994-07-15 | 2001-12-13 | Muneo Takatani | Tricyclic compounds, their production and use |
| DK0831910T3 (da) * | 1995-06-07 | 2002-05-21 | Searle & Co | Kombinationsterapi med epoxy-steroid aldosteronantagonist og angiotensin II-receptorantagonist til behandling af kongestivt hjertesvigt |
| CO4940418A1 (es) * | 1997-07-18 | 2000-07-24 | Novartis Ag | Modificacion de cristal de un derivado de n-fenil-2- pirimidinamina, procesos para su fabricacion y su uso |
-
2003
- 2003-03-14 AU AU2003233946A patent/AU2003233946A1/en not_active Abandoned
- 2003-03-14 US US10/507,642 patent/US20050124624A1/en not_active Abandoned
- 2003-03-14 EP EP03727265A patent/EP1487424B1/en not_active Expired - Lifetime
- 2003-03-14 DE DE60308337T patent/DE60308337T2/de not_active Expired - Lifetime
- 2003-03-14 PT PT03727265T patent/PT1487424E/pt unknown
- 2003-03-14 WO PCT/EP2003/002709 patent/WO2003077892A2/en not_active Ceased
- 2003-03-14 AT AT03727265T patent/ATE339197T1/de active
- 2003-03-14 JP JP2003575945A patent/JP2005527523A/ja active Pending
- 2003-03-14 DK DK03727265T patent/DK1487424T3/da active
- 2003-03-14 ES ES03727265T patent/ES2274234T3/es not_active Expired - Lifetime
-
2006
- 2006-12-11 CY CY20061101774T patent/CY1105839T1/el unknown
Also Published As
| Publication number | Publication date |
|---|---|
| DE60308337T2 (de) | 2007-09-20 |
| CY1105839T1 (el) | 2011-04-06 |
| AU2003233946A8 (en) | 2003-09-29 |
| DE60308337D1 (de) | 2006-10-26 |
| DK1487424T3 (da) | 2007-01-08 |
| AU2003233946A1 (en) | 2003-09-29 |
| ATE339197T1 (de) | 2006-10-15 |
| WO2003077892A2 (en) | 2003-09-25 |
| ES2274234T3 (es) | 2007-05-16 |
| US20050124624A1 (en) | 2005-06-09 |
| EP1487424A2 (en) | 2004-12-22 |
| JP2005527523A (ja) | 2005-09-15 |
| WO2003077892A3 (en) | 2003-12-24 |
| EP1487424B1 (en) | 2006-09-13 |
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