PT1474415E - Derivados de benzimidazol substituídos em 1-fenilo-2- heteroarilo, o seu uso para a produção de fármacos para o tratamento de doenças imunológicas - Google Patents

Derivados de benzimidazol substituídos em 1-fenilo-2- heteroarilo, o seu uso para a produção de fármacos para o tratamento de doenças imunológicas Download PDF

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Publication number
PT1474415E
PT1474415E PT03702464T PT03702464T PT1474415E PT 1474415 E PT1474415 E PT 1474415E PT 03702464 T PT03702464 T PT 03702464T PT 03702464 T PT03702464 T PT 03702464T PT 1474415 E PT1474415 E PT 1474415E
Authority
PT
Portugal
Prior art keywords
heteroaryl
phenyl
treatment
drugs used
benzimidazole derivatives
Prior art date
Application number
PT03702464T
Other languages
English (en)
Inventor
Joachim Kuhnke
Wolfgang Halfbrodt
Ursula Moenning
Herbert Schneider
Thorsten Blume
Bernd Elger
Original Assignee
Bayer Schering Pharma Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bayer Schering Pharma Ag filed Critical Bayer Schering Pharma Ag
Publication of PT1474415E publication Critical patent/PT1474415E/pt

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Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D401/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/04Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/02Immunomodulators
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/02Immunomodulators
    • A61P37/06Immunosuppressants, e.g. drugs for graft rejection
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/08Antiallergic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D409/00Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/02Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
    • C07D409/04Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D413/00Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/14Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing three or more hetero rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D417/00Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/14Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing three or more hetero rings

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Immunology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Transplantation (AREA)
  • Pulmonology (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
PT03702464T 2002-02-15 2003-01-17 Derivados de benzimidazol substituídos em 1-fenilo-2- heteroarilo, o seu uso para a produção de fármacos para o tratamento de doenças imunológicas PT1474415E (pt)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE10207844A DE10207844A1 (de) 2002-02-15 2002-02-15 1-Phenyl-2-heteroaryl-substituierte Benzimidazolderivate, deren Verwendung zur Herstellung von Arzneimitteln sowie diese Derivate enthaltende pharmazeutische Präparate

Publications (1)

Publication Number Publication Date
PT1474415E true PT1474415E (pt) 2011-10-13

Family

ID=27674913

Family Applications (1)

Application Number Title Priority Date Filing Date
PT03702464T PT1474415E (pt) 2002-02-15 2003-01-17 Derivados de benzimidazol substituídos em 1-fenilo-2- heteroarilo, o seu uso para a produção de fármacos para o tratamento de doenças imunológicas

Country Status (30)

Country Link
EP (1) EP1474415B1 (pt)
JP (1) JP4739675B2 (pt)
KR (1) KR101027556B1 (pt)
CN (1) CN1317274C (pt)
AR (1) AR038492A1 (pt)
AT (1) ATE517881T1 (pt)
AU (1) AU2003205624B2 (pt)
BR (1) BR0307723A (pt)
CA (1) CA2475780C (pt)
CR (1) CR7442A (pt)
CY (1) CY1113230T1 (pt)
DE (1) DE10207844A1 (pt)
DK (1) DK1474415T3 (pt)
EC (1) ECSP045296A (pt)
ES (1) ES2369662T3 (pt)
IL (1) IL163431A (pt)
MX (1) MXPA04007949A (pt)
NO (1) NO329667B1 (pt)
NZ (1) NZ534660A (pt)
PE (1) PE20030941A1 (pt)
PL (1) PL216233B1 (pt)
PT (1) PT1474415E (pt)
RS (1) RS51831B (pt)
RU (1) RU2325384C2 (pt)
SI (1) SI1474415T1 (pt)
TW (1) TWI328583B (pt)
UA (1) UA81243C2 (pt)
UY (1) UY27661A1 (pt)
WO (1) WO2003068766A1 (pt)
ZA (1) ZA200407381B (pt)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DK1497266T3 (da) 2002-03-27 2008-10-06 Glaxo Group Ltd Quinolinderivater og deres anvendelse som 5HT6-ligander
WO2004103309A2 (en) * 2003-05-19 2004-12-02 Irm Llc Immunosuppressant compounds and compositions
WO2014044611A1 (en) 2012-09-20 2014-03-27 Bayer Pharma Aktiengesellschaft 1-aryl-2-heteroaryl benzimidazoles for the induction of neuronal regeneration

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE4330959A1 (de) * 1993-09-09 1995-03-16 Schering Ag Neue Benzimidazolderivate, Verfahren zu ihrer Herstellung und ihre pharmazeutische Verwendung
HU228366B1 (en) * 2000-01-14 2013-03-28 Schering Ag 1,2-diaryl benzimidazoles, pharmaceutical compositions containing them and their use for producing pharmaceutical compositions for treating illnesses associated with a microglia activation
US7115645B2 (en) * 2000-01-14 2006-10-03 Schering Aktiengesellschaft 1,2 diarylbenzimidazoles and their pharmaceutical use
DE10207843A1 (de) * 2002-02-15 2003-09-04 Schering Ag Mikrolia-Inhibitoren zur Unterbrechung von Interleukin 12 und IFN-gamma vermittelten Immunreaktionen

Also Published As

Publication number Publication date
CA2475780A1 (en) 2003-08-21
CR7442A (es) 2006-02-06
KR101027556B1 (ko) 2011-04-06
WO2003068766A1 (de) 2003-08-21
EP1474415A1 (de) 2004-11-10
NO329667B1 (no) 2010-11-29
UA81243C2 (en) 2007-12-25
CN1317274C (zh) 2007-05-23
ES2369662T3 (es) 2011-12-02
JP4739675B2 (ja) 2011-08-03
RU2325384C2 (ru) 2008-05-27
TW200303307A (en) 2003-09-01
IL163431A (en) 2010-11-30
ATE517881T1 (de) 2011-08-15
TWI328583B (en) 2010-08-11
RS71404A (en) 2006-10-27
JP2005521686A (ja) 2005-07-21
DK1474415T3 (da) 2011-11-21
EP1474415B1 (de) 2011-07-27
ZA200407381B (en) 2005-11-30
PL216233B1 (pl) 2014-03-31
RS51831B (en) 2012-02-29
AU2003205624A1 (en) 2003-09-04
CY1113230T1 (el) 2016-04-13
AR038492A1 (es) 2005-01-19
KR20040081795A (ko) 2004-09-22
NZ534660A (en) 2006-02-24
MXPA04007949A (es) 2004-11-26
RU2004127678A (ru) 2005-07-10
DE10207844A1 (de) 2003-09-04
CN1633429A (zh) 2005-06-29
NO20043841L (no) 2004-11-12
AU2003205624B2 (en) 2009-08-27
BR0307723A (pt) 2005-01-25
PE20030941A1 (es) 2004-01-17
CA2475780C (en) 2011-08-02
ECSP045296A (es) 2004-10-26
UY27661A1 (es) 2003-09-30
PL371269A1 (en) 2005-06-13
SI1474415T1 (sl) 2011-12-30

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