PT1461428E - Método para produção de anticorpos híbridos - Google Patents
Método para produção de anticorpos híbridos Download PDFInfo
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- PT1461428E PT1461428E PT02794114T PT02794114T PT1461428E PT 1461428 E PT1461428 E PT 1461428E PT 02794114 T PT02794114 T PT 02794114T PT 02794114 T PT02794114 T PT 02794114T PT 1461428 E PT1461428 E PT 1461428E
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Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
- C07K2317/56—Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
- C07K2317/565—Complementarity determining region [CDR]
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- Life Sciences & Earth Sciences (AREA)
- Genetics & Genomics (AREA)
- Medicinal Chemistry (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Immunology (AREA)
- Peptides Or Proteins (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US33659101P | 2001-12-03 | 2001-12-03 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| PT1461428E true PT1461428E (pt) | 2012-05-29 |
Family
ID=23316785
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PT02794114T PT1461428E (pt) | 2001-12-03 | 2002-12-03 | Método para produção de anticorpos híbridos |
Country Status (12)
| Country | Link |
|---|---|
| US (1) | US7399594B2 (enExample) |
| EP (2) | EP1461428B1 (enExample) |
| JP (3) | JP4723810B2 (enExample) |
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| SI (1) | SI1461428T1 (enExample) |
| WO (1) | WO2003048321A2 (enExample) |
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| DE10353175A1 (de) * | 2003-11-14 | 2005-06-16 | Müller-Hermelink, Hans Konrad, Prof. Dr. | Humaner monoklonaler Antikörper mit fettsenkender Wirkung |
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| JP2012508022A (ja) * | 2008-11-06 | 2012-04-05 | アレクシオン ファーマシューティカルズ, インコーポレイテッド | 減少した免疫原性を有する操作された抗体および作製方法 |
| US8569460B2 (en) * | 2009-03-25 | 2013-10-29 | Vet Therapeutics, Inc. | Antibody constant domain regions and uses thereof |
| US9616120B2 (en) * | 2010-03-04 | 2017-04-11 | Vet Therapeutics, Inc. | Monoclonal antibodies directed to CD20 |
| BR112012022342A2 (pt) * | 2010-03-04 | 2017-02-14 | Vet Therapeutics Inc | anticorpos monoclonais dirigidos a cd52 |
| AU2011268110B2 (en) | 2010-06-19 | 2016-05-19 | Memorial Sloan-Kettering Cancer Center | Anti-GD2 antibodies |
| CN102251013A (zh) * | 2011-02-22 | 2011-11-23 | 北京市肿瘤防治研究所 | 一个识别肿瘤起始细胞的抗体和抗原及其应用 |
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| HRP20182129T1 (hr) * | 2012-10-12 | 2019-02-08 | Adc Therapeutics Sa | Konjugati protutijelo - pirolobenzodiazepin |
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| GB201602356D0 (en) | 2016-02-10 | 2016-03-23 | Medimmune Ltd | Pyrrolobenzodiazepine Conjugates |
| GB201602359D0 (en) | 2016-02-10 | 2016-03-23 | Medimmune Ltd | Pyrrolobenzodiazepine Conjugates |
| GB201607478D0 (en) | 2016-04-29 | 2016-06-15 | Medimmune Ltd | Pyrrolobenzodiazepine Conjugates |
| GB201617466D0 (en) | 2016-10-14 | 2016-11-30 | Medimmune Ltd | Pyrrolobenzodiazepine conjugates |
| GB201702031D0 (en) | 2017-02-08 | 2017-03-22 | Medlmmune Ltd | Pyrrolobenzodiazepine-antibody conjugates |
| KR20200032243A (ko) | 2017-02-08 | 2020-03-25 | 에이디씨 테라퓨틱스 에스에이 | 피롤로벤조디아제핀-항체 컨주게이트 |
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| EP3612234B1 (en) | 2017-04-20 | 2024-03-13 | ADC Therapeutics SA | Combination therapy with an anti-axl antibody-drug conjugate |
| KR102442736B1 (ko) | 2017-06-14 | 2022-09-16 | 에이디씨 테라퓨틱스 에스에이 | 항-cd19 adc의 투여를 위한 투약량 체제 |
| CN111065638B (zh) | 2017-08-18 | 2021-04-09 | 麦迪穆有限责任公司 | 吡咯并苯并二氮杂䓬缀合物 |
| GB201803342D0 (en) | 2018-03-01 | 2018-04-18 | Medimmune Ltd | Methods |
| GB201806022D0 (en) | 2018-04-12 | 2018-05-30 | Medimmune Ltd | Pyrrolobenzodiazepines and conjugates thereof |
| IL286326B2 (en) | 2019-03-15 | 2025-10-01 | Medimmune Ltd | Azatidobenzodiazepine dimers and conjugates containing them for use in the treatment of cancer |
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| US4470925A (en) * | 1982-05-05 | 1984-09-11 | E. I. Du Pont De Nemours And Company | Immunoglobulin half-molecules and process for producing hybrid antibodies |
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| ATE408012T1 (de) | 1991-12-02 | 2008-09-15 | Medical Res Council | Herstellung von autoantikörpern auf phagenoberflächen ausgehend von antikörpersegmentbibliotheken |
| US5643756A (en) | 1992-08-28 | 1997-07-01 | The Public Health Research Institute Of The City Of New York, Inc. | Fusion glycoproteins |
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| US5908925A (en) * | 1996-06-27 | 1999-06-01 | Exocell, Inc. | Genetically engineered immunoglobulins with specificity for glycated albumin |
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| US7321026B2 (en) * | 2001-06-27 | 2008-01-22 | Skytech Technology Limited | Framework-patched immunoglobulins |
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| US20030190705A1 (en) * | 2001-10-29 | 2003-10-09 | Sunol Molecular Corporation | Method of humanizing immune system molecules |
-
2002
- 2002-12-03 ES ES02794114T patent/ES2384100T3/es not_active Expired - Lifetime
- 2002-12-03 AT AT02794114T patent/ATE550352T1/de active
- 2002-12-03 DK DK02794114.5T patent/DK1461428T3/da active
- 2002-12-03 WO PCT/US2002/038450 patent/WO2003048321A2/en not_active Ceased
- 2002-12-03 AU AU2002359568A patent/AU2002359568B2/en not_active Ceased
- 2002-12-03 SI SI200230983T patent/SI1461428T1/sl unknown
- 2002-12-03 EP EP02794114A patent/EP1461428B1/en not_active Expired - Lifetime
- 2002-12-03 JP JP2003549500A patent/JP4723810B2/ja not_active Expired - Fee Related
- 2002-12-03 PT PT02794114T patent/PT1461428E/pt unknown
- 2002-12-03 EP EP10178484A patent/EP2298817A1/en not_active Withdrawn
- 2002-12-03 CA CA2468744A patent/CA2468744C/en not_active Expired - Fee Related
- 2002-12-03 US US10/308,817 patent/US7399594B2/en not_active Expired - Lifetime
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2009
- 2009-04-06 JP JP2009092502A patent/JP5054058B2/ja not_active Expired - Fee Related
-
2012
- 2012-03-13 JP JP2012056050A patent/JP2012144551A/ja not_active Withdrawn
- 2012-06-07 CY CY20121100520T patent/CY1112843T1/el unknown
Also Published As
| Publication number | Publication date |
|---|---|
| JP4723810B2 (ja) | 2011-07-13 |
| SI1461428T1 (sl) | 2012-07-31 |
| JP2009153527A (ja) | 2009-07-16 |
| US20030219861A1 (en) | 2003-11-27 |
| US7399594B2 (en) | 2008-07-15 |
| CA2468744A1 (en) | 2003-06-12 |
| EP1461428B1 (en) | 2012-03-21 |
| WO2003048321A2 (en) | 2003-06-12 |
| JP2012144551A (ja) | 2012-08-02 |
| ES2384100T3 (es) | 2012-06-29 |
| WO2003048321A3 (en) | 2003-10-16 |
| ATE550352T1 (de) | 2012-04-15 |
| EP2298817A1 (en) | 2011-03-23 |
| EP1461428A4 (en) | 2005-05-25 |
| CY1112843T1 (el) | 2016-02-10 |
| JP5054058B2 (ja) | 2012-10-24 |
| CA2468744C (en) | 2013-05-14 |
| DK1461428T3 (da) | 2012-06-04 |
| JP2005511706A (ja) | 2005-04-28 |
| AU2002359568A1 (en) | 2003-06-17 |
| EP1461428A2 (en) | 2004-09-29 |
| AU2002359568B2 (en) | 2008-02-21 |
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