SI1461428T1 - Postopek za proizvodnjo hibridnih protiteles - Google Patents

Postopek za proizvodnjo hibridnih protiteles

Info

Publication number
SI1461428T1
SI1461428T1 SI200230983T SI200230983T SI1461428T1 SI 1461428 T1 SI1461428 T1 SI 1461428T1 SI 200230983 T SI200230983 T SI 200230983T SI 200230983 T SI200230983 T SI 200230983T SI 1461428 T1 SI1461428 T1 SI 1461428T1
Authority
SI
Slovenia
Prior art keywords
hybrid
antibodies
framework regions
hybrid antibodies
antibody fragments
Prior art date
Application number
SI200230983T
Other languages
English (en)
Slovenian (sl)
Inventor
Russell Rother
Dayang Wu
Original Assignee
Alexion Pharma Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Alexion Pharma Inc filed Critical Alexion Pharma Inc
Publication of SI1461428T1 publication Critical patent/SI1461428T1/sl

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/56—Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
    • C07K2317/565—Complementarity determining region [CDR]

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Immunology (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
SI200230983T 2001-12-03 2002-12-03 Postopek za proizvodnjo hibridnih protiteles SI1461428T1 (sl)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US33659101P 2001-12-03 2001-12-03
PCT/US2002/038450 WO2003048321A2 (en) 2001-12-03 2002-12-03 Hybrid antibodies
EP02794114A EP1461428B1 (en) 2001-12-03 2002-12-03 Method for producing hybrid antibodies

Publications (1)

Publication Number Publication Date
SI1461428T1 true SI1461428T1 (sl) 2012-07-31

Family

ID=23316785

Family Applications (1)

Application Number Title Priority Date Filing Date
SI200230983T SI1461428T1 (sl) 2001-12-03 2002-12-03 Postopek za proizvodnjo hibridnih protiteles

Country Status (12)

Country Link
US (1) US7399594B2 (enExample)
EP (2) EP1461428B1 (enExample)
JP (3) JP4723810B2 (enExample)
AT (1) ATE550352T1 (enExample)
AU (1) AU2002359568B2 (enExample)
CA (1) CA2468744C (enExample)
CY (1) CY1112843T1 (enExample)
DK (1) DK1461428T3 (enExample)
ES (1) ES2384100T3 (enExample)
PT (1) PT1461428E (enExample)
SI (1) SI1461428T1 (enExample)
WO (1) WO2003048321A2 (enExample)

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US8569460B2 (en) * 2009-03-25 2013-10-29 Vet Therapeutics, Inc. Antibody constant domain regions and uses thereof
US9616120B2 (en) * 2010-03-04 2017-04-11 Vet Therapeutics, Inc. Monoclonal antibodies directed to CD20
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JP6392764B2 (ja) 2012-10-12 2018-09-19 エイディーシー・セラピューティクス・エス・アーＡｄｃ Ｔｈｅｒａｐｅｕｔｉｃｓ Ｓａ ピロロベンゾジアゼピン−抗体結合体
HRP20182129T1 (hr) * 2012-10-12 2019-02-08 Adc Therapeutics Sa Konjugati protutijelo - pirolobenzodiazepin
HUE045435T2 (hu) 2012-10-12 2019-12-30 Medimmune Ltd Pirrolobenzodiazepinek és konjugátumaik
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US9950078B2 (en) 2013-10-11 2018-04-24 Medimmune Limited Pyrrolobenzodiazepine-antibody conjugates
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GB201601431D0 (en) 2016-01-26 2016-03-09 Medimmune Ltd Pyrrolobenzodiazepines
GB201602356D0 (en) 2016-02-10 2016-03-23 Medimmune Ltd Pyrrolobenzodiazepine Conjugates
GB201602359D0 (en) 2016-02-10 2016-03-23 Medimmune Ltd Pyrrolobenzodiazepine Conjugates
GB201607478D0 (en) 2016-04-29 2016-06-15 Medimmune Ltd Pyrrolobenzodiazepine Conjugates
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GB201702031D0 (en) 2017-02-08 2017-03-22 Medlmmune Ltd Pyrrolobenzodiazepine-antibody conjugates
KR20200032243A (ko) 2017-02-08 2020-03-25 에이디씨 테라퓨틱스 에스에이 피롤로벤조디아제핀-항체 컨주게이트
SI3612537T1 (sl) 2017-04-18 2022-10-28 Medimmune Limited Konjugati pirolobenzodiazepina
EP3612234B1 (en) 2017-04-20 2024-03-13 ADC Therapeutics SA Combination therapy with an anti-axl antibody-drug conjugate
KR102442736B1 (ko) 2017-06-14 2022-09-16 에이디씨 테라퓨틱스 에스에이 항-cd19 adc의 투여를 위한 투약량 체제
CN111065638B (zh) 2017-08-18 2021-04-09 麦迪穆有限责任公司 吡咯并苯并二氮杂䓬缀合物
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IL286326B2 (en) 2019-03-15 2025-10-01 Medimmune Ltd Azatidobenzodiazepine dimers and conjugates containing them for use in the treatment of cancer

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Also Published As

Publication number Publication date
JP4723810B2 (ja) 2011-07-13
JP2009153527A (ja) 2009-07-16
US20030219861A1 (en) 2003-11-27
US7399594B2 (en) 2008-07-15
CA2468744A1 (en) 2003-06-12
EP1461428B1 (en) 2012-03-21
WO2003048321A2 (en) 2003-06-12
JP2012144551A (ja) 2012-08-02
ES2384100T3 (es) 2012-06-29
WO2003048321A3 (en) 2003-10-16
ATE550352T1 (de) 2012-04-15
EP2298817A1 (en) 2011-03-23
EP1461428A4 (en) 2005-05-25
CY1112843T1 (el) 2016-02-10
JP5054058B2 (ja) 2012-10-24
CA2468744C (en) 2013-05-14
DK1461428T3 (da) 2012-06-04
JP2005511706A (ja) 2005-04-28
PT1461428E (pt) 2012-05-29
AU2002359568A1 (en) 2003-06-17
EP1461428A2 (en) 2004-09-29
AU2002359568B2 (en) 2008-02-21

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