PT1300401E - Derivados de tiazole para utilização como anti-inflamatórios - Google Patents

Derivados de tiazole para utilização como anti-inflamatórios Download PDF

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Publication number
PT1300401E
PT1300401E PT01943850T PT01943850T PT1300401E PT 1300401 E PT1300401 E PT 1300401E PT 01943850 T PT01943850 T PT 01943850T PT 01943850 T PT01943850 T PT 01943850T PT 1300401 E PT1300401 E PT 1300401E
Authority
PT
Portugal
Prior art keywords
substituted
unsubstituted
hydrogen
antiinflammatories
unsubstituted alkyl
Prior art date
Application number
PT01943850T
Other languages
English (en)
Inventor
Hajime Kawakami
Norio Fujiwara
Hitoshi Fujita
Fujio Antoku
Toshinari Sugasawa
Original Assignee
Dainippon Sumitomo Pharma Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Dainippon Sumitomo Pharma Co filed Critical Dainippon Sumitomo Pharma Co
Publication of PT1300401E publication Critical patent/PT1300401E/pt

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
    • C07D231/02—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
    • C07D231/10—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D231/12—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/08—Antiallergic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
    • C07D233/56—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, attached to ring carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D249/00—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms
    • C07D249/02—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms not condensed with other rings
    • C07D249/08—1,2,4-Triazoles; Hydrogenated 1,2,4-triazoles
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
    • C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
    • C07D277/20—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D277/32—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D277/38—Nitrogen atoms
    • C07D277/42—Amino or imino radicals substituted by hydrocarbon or substituted hydrocarbon radicals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/06—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing three or more hetero rings
PT01943850T 2000-06-30 2001-06-28 Derivados de tiazole para utilização como anti-inflamatórios PT1300401E (pt)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP2000198074 2000-06-30

Publications (1)

Publication Number Publication Date
PT1300401E true PT1300401E (pt) 2010-01-25

Family

ID=18696291

Family Applications (1)

Application Number Title Priority Date Filing Date
PT01943850T PT1300401E (pt) 2000-06-30 2001-06-28 Derivados de tiazole para utilização como anti-inflamatórios

Country Status (15)

Country Link
US (2) US6919361B2 (pt)
EP (2) EP1300401B1 (pt)
JP (1) JP3785397B2 (pt)
KR (2) KR100758775B1 (pt)
CN (2) CN100369903C (pt)
AT (1) ATE451102T1 (pt)
AU (2) AU6634501A (pt)
CA (1) CA2413000C (pt)
CY (1) CY1109863T1 (pt)
DE (1) DE60140748D1 (pt)
DK (1) DK1300401T3 (pt)
ES (1) ES2336425T3 (pt)
PT (1) PT1300401E (pt)
TW (1) TWI313266B (pt)
WO (1) WO2002002542A1 (pt)

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WO2003057693A1 (fr) * 2001-12-28 2003-07-17 Sumitomo Pharmaceuticals Co., Ltd. Composes cycliques a 5 chainons
EP1348433A1 (en) * 2002-03-28 2003-10-01 Warner-Lambert Company LLC Thiazol-2-yl-imine compounds as PDE-7 inhibitors
DE10254336A1 (de) * 2002-11-21 2004-06-03 Merck Patent Gmbh Carbonsäureamide
EP1640369A4 (en) * 2003-06-27 2007-10-31 Dainippon Sumitomo Pharma Co THIAZOLIMINE COMPOUND AND OXAZOLIMINE COMPOUND
EP2202745A3 (en) * 2003-10-10 2010-07-28 Sharp Kabushiki Kaisha A reproducing apparatus, a reproducing method, a recording medium, a control program and a computer-readable recording medium
MY162179A (en) * 2004-04-01 2017-05-31 Elan Pharm Inc Steroid sparing agents and methods of using same
US20080312435A1 (en) * 2004-11-15 2008-12-18 Taisho Pharmaceutical Co., Ltd. Imine Compound
WO2006118268A1 (ja) * 2005-04-28 2006-11-09 Dainippon Sumitomo Pharma Co., Ltd. 慢性閉塞性肺疾患治療剤
JP2007015999A (ja) * 2005-07-11 2007-01-25 Sumitomo Chemical Co Ltd イミノチアゾール化合物の製造方法
WO2007132546A1 (ja) * 2006-05-11 2007-11-22 Dainippon Sumitomo Pharma Co., Ltd. チアゾール誘導体を有効成分とする医薬
EP2024349B1 (en) 2006-05-31 2017-08-02 AbbVie Inc. Compounds as cannabinoid receptor ligands and uses thereof
US8841334B2 (en) 2006-05-31 2014-09-23 Abbvie Inc. Compounds as cannabinoid receptor ligands and uses thereof
CN101765594A (zh) 2007-03-28 2010-06-30 雅培制药有限公司 作为大麻素受体配体的1,3-噻唑-2(3h)-亚基化合物
US7872033B2 (en) 2007-04-17 2011-01-18 Abbott Laboratories Compounds as cannabinoid receptor ligands
US8735434B2 (en) 2007-05-18 2014-05-27 Abbvie Inc. Compounds as cannabinoid receptor ligands
KR100863239B1 (ko) * 2007-05-23 2008-10-15 한국과학기술연구원 신규한 2-이미노-1,3-티아졸린계 화합물 및 이를 함유하는ｔ-형 칼슘 채널 저해제
US9193713B2 (en) * 2007-10-12 2015-11-24 Abbvie Inc. Compounds as cannabinoid receptor ligands
US20110039848A1 (en) * 2008-04-25 2011-02-17 Hitoshi Fujita Five-membered ring compound
US20110034466A1 (en) * 2008-04-25 2011-02-10 Hitoshi Fujita Novel five-membered ring compound
US8846730B2 (en) 2008-09-08 2014-09-30 Abbvie Inc. Compounds as cannabinoid receptor ligands
JP2012502917A (ja) 2008-09-16 2012-02-02 アボット・ラボラトリーズ カンナビノイド受容体リガンドとしての置換ベンズアミド類
PA8854001A1 (es) 2008-12-16 2010-07-27 Abbott Lab Compuestos novedosos como ligandos de receptores de canabinoides
CN102448957A (zh) 2009-03-27 2012-05-09 雅培制药有限公司 作为大麻素受体配体的化合物
WO2014052831A1 (en) * 2012-09-28 2014-04-03 Xavier University Of Louisiana Anti-migration and anti-invasion thiazole analogs for treatment of cellular proliferative disease

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EP0848059A1 (en) 1996-12-12 1998-06-17 Vetigen Mammalian ICYP (Iodocyanopindolol) receptor and its applications
US7076307B2 (en) * 2002-05-09 2006-07-11 Boveja Birinder R Method and system for modulating the vagus nerve (10th cranial nerve) with electrical pulses using implanted and external components, to provide therapy neurological and neuropsychiatric disorders
FR2796643B1 (fr) * 1999-07-22 2005-04-29 Sod Conseils Rech Applic Derives de 2-arylimino-2, 3-dihydrothiazoles, leurs procedes de preparation et leur utilisation therapeutique
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Also Published As

Publication number Publication date
AU6634501A (en) 2002-01-14
ES2336425T3 (es) 2010-04-13
CA2413000C (en) 2010-01-19
JP3785397B2 (ja) 2006-06-14
DK1300401T3 (da) 2010-02-01
CA2413000A1 (en) 2002-01-10
WO2002002542A1 (en) 2002-01-10
DE60140748D1 (de) 2010-01-21
US7396842B2 (en) 2008-07-08
EP1300401A4 (en) 2004-07-21
ATE451102T1 (de) 2009-12-15
KR20070086998A (ko) 2007-08-27
EP1300401B1 (en) 2009-12-09
US6919361B2 (en) 2005-07-19
CY1109863T1 (el) 2014-09-10
EP1669070A2 (en) 2006-06-14
AU2001266345B2 (en) 2006-03-02
KR100758775B1 (ko) 2007-09-14
KR100824156B1 (ko) 2008-04-21
US20050222226A1 (en) 2005-10-06
KR20030011377A (ko) 2003-02-07
CN100369903C (zh) 2008-02-20
EP1300401A1 (en) 2003-04-09
CN1620442A (zh) 2005-05-25
US20040072827A1 (en) 2004-04-15
TWI313266B (en) 2009-08-11
EP1669070A3 (en) 2007-05-23
CN1944417A (zh) 2007-04-11

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