PT1276770E - Proteínas com elevada imunorreactividade, assim como um processo para a sua produção - Google Patents
Proteínas com elevada imunorreactividade, assim como um processo para a sua produção Download PDFInfo
- Publication number
- PT1276770E PT1276770E PT01931566T PT01931566T PT1276770E PT 1276770 E PT1276770 E PT 1276770E PT 01931566 T PT01931566 T PT 01931566T PT 01931566 T PT01931566 T PT 01931566T PT 1276770 E PT1276770 E PT 1276770E
- Authority
- PT
- Portugal
- Prior art keywords
- monoclonal antibodies
- proteins
- produced
- labeled
- purification method
- Prior art date
Links
- 238000000034 method Methods 0.000 title abstract 3
- 102000004169 proteins and genes Human genes 0.000 title abstract 2
- 108090000623 proteins and genes Proteins 0.000 title abstract 2
- 238000000746 purification Methods 0.000 abstract 2
- 206010027476 Metastases Diseases 0.000 abstract 1
- 229910052789 astatine Inorganic materials 0.000 abstract 1
- RYXHOMYVWAEKHL-UHFFFAOYSA-N astatine atom Chemical compound [At] RYXHOMYVWAEKHL-UHFFFAOYSA-N 0.000 abstract 1
- 210000001185 bone marrow Anatomy 0.000 abstract 1
- 238000004440 column chromatography Methods 0.000 abstract 1
- 238000003745 diagnosis Methods 0.000 abstract 1
- 238000001727 in vivo Methods 0.000 abstract 1
- 208000027866 inflammatory disease Diseases 0.000 abstract 1
- 208000032839 leukemia Diseases 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
- A61K51/02—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
- A61K51/04—Organic compounds
- A61K51/08—Peptides, e.g. proteins, carriers being peptides, polyamino acids, proteins
- A61K51/10—Antibodies or immunoglobulins; Fragments thereof, the carrier being an antibody, an immunoglobulin or a fragment thereof, e.g. a camelised human single domain antibody or the Fc fragment of an antibody
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/02—Antineoplastic agents specific for leukemia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/04—Antineoplastic agents specific for metastasis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Organic Chemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Immunology (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Genetics & Genomics (AREA)
- Optics & Photonics (AREA)
- Epidemiology (AREA)
- Molecular Biology (AREA)
- Biophysics (AREA)
- Biochemistry (AREA)
- Physics & Mathematics (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Hematology (AREA)
- Oncology (AREA)
- Diabetes (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Peptides Or Proteins (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE10016877A DE10016877A1 (de) | 2000-04-05 | 2000-04-05 | (Glyko-)Proteine mit hoher Immunreaktivität sowie ein Verfahren zu ihrer Herstellung |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| PT1276770E true PT1276770E (pt) | 2008-01-24 |
Family
ID=7637638
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PT01931566T PT1276770E (pt) | 2000-04-05 | 2001-04-04 | Proteínas com elevada imunorreactividade, assim como um processo para a sua produção |
Country Status (10)
| Country | Link |
|---|---|
| US (3) | US7264805B2 (enExample) |
| EP (1) | EP1276770B1 (enExample) |
| JP (1) | JP4880854B2 (enExample) |
| AT (1) | ATE376000T1 (enExample) |
| CY (1) | CY1107136T1 (enExample) |
| DE (2) | DE10016877A1 (enExample) |
| DK (1) | DK1276770T3 (enExample) |
| ES (1) | ES2295160T3 (enExample) |
| PT (1) | PT1276770E (enExample) |
| WO (1) | WO2001077179A1 (enExample) |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE10016877A1 (de) * | 2000-04-05 | 2001-10-18 | Scintec Diagnostics Gmbh Zug | (Glyko-)Proteine mit hoher Immunreaktivität sowie ein Verfahren zu ihrer Herstellung |
| RU2016134843A (ru) | 2009-04-30 | 2018-12-11 | Тел Хашомер Медикал Рисерч Инфрастракче Энд Сервисиз Лтд. | Антитела к ceacam1 и способы их использования |
| WO2013054320A1 (en) | 2011-10-11 | 2013-04-18 | Tel Hashomer Medical Research Infrastructure And Services Ltd. | Antibodies to carcinoembryonic antigen-related cell adhesion molecule (ceacam) |
| KR102452349B1 (ko) | 2014-04-27 | 2022-10-11 | 페임웨이브 리미티드 | Ceacam1에 대한 인간화 항체 |
| US11427647B2 (en) | 2014-04-27 | 2022-08-30 | Famewave Ltd. | Polynucleotides encoding humanized antibodies against CEACAM1 |
Family Cites Families (16)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU5452986A (en) * | 1985-02-28 | 1986-09-24 | Verax Corp. | Fluidized bioreactor and cell cultivation process |
| US5164175A (en) * | 1986-12-10 | 1992-11-17 | Hoechst Aktiengesellschaft | Diagnostic aid containing an organ-specific substance labeled with technetium-99m |
| US4939087A (en) * | 1987-05-12 | 1990-07-03 | Washington State University Research Foundation, Inc. | Method for continuous centrifugal bioprocessing |
| US5132405A (en) * | 1987-05-21 | 1992-07-21 | Creative Biomolecules, Inc. | Biosynthetic antibody binding sites |
| US4873316A (en) * | 1987-06-23 | 1989-10-10 | Biogen, Inc. | Isolation of exogenous recombinant proteins from the milk of transgenic mammals |
| IL83878A (en) | 1987-09-13 | 1995-07-31 | Yeda Res & Dev | Soluble protein corresponding to tnf inhibitory protein its preparation and pharmaceutical compositions containing it |
| DE4125625C2 (de) * | 1991-08-02 | 1999-12-02 | Octapharma Ag Glarus | Verfahren zur Herstellung von virusinaktivierten Immunglobulinlösungen |
| AU667530B2 (en) * | 1992-05-28 | 1996-03-28 | New York Blood Center, Inc., The | Removal of antibodies from blood-derived compositions while retaining coagulation factors |
| DE4225853A1 (de) * | 1992-08-05 | 1994-02-10 | Behringwerke Ag | Granulozytenbindende Antikörperfragmente, ihre Herstellung und Verwendung |
| SE9500148D0 (sv) | 1995-01-18 | 1995-01-18 | Bioinvent Internatioal Ab | Antibodies for use in cancer therapy and diagnosis |
| EP0727480A3 (de) | 1995-02-16 | 2000-04-12 | Forschungszentrum Jülich Gmbh | Verfahren zur Bestimmung von Pharmakokinetik bzw. Toxikokinetik von Testsubstanzen mit Hilfe von in-vitro-Zellkultursystemen und dafür geeignete Vorrichtungen |
| DE19521388C2 (de) | 1995-06-13 | 1997-05-22 | Immuno Gmbh | Technik zur Bestimmung einer spezifisch-bindefähigen Substanz |
| DE19621388A1 (de) | 1996-05-28 | 1997-12-11 | Torsten Urban | Das Tapeten- bzw. Rauhfaserset |
| DE19744531A1 (de) | 1997-10-09 | 1999-05-27 | Klaus Dr Rer Nat Bosslet | Bindemoleküle gegen Rezeptor-Ligand-Komplexe |
| DE19911329A1 (de) * | 1998-03-27 | 2000-09-21 | Benes Ivan Friedrich | Humantherapeutisch anwendbares Radioimmunkonjugat und Verfahren zu seiner Herstellung |
| DE10016877A1 (de) * | 2000-04-05 | 2001-10-18 | Scintec Diagnostics Gmbh Zug | (Glyko-)Proteine mit hoher Immunreaktivität sowie ein Verfahren zu ihrer Herstellung |
-
2000
- 2000-04-05 DE DE10016877A patent/DE10016877A1/de not_active Ceased
-
2001
- 2001-04-04 WO PCT/EP2001/003867 patent/WO2001077179A1/de not_active Ceased
- 2001-04-04 ES ES01931566T patent/ES2295160T3/es not_active Expired - Lifetime
- 2001-04-04 DK DK01931566T patent/DK1276770T3/da active
- 2001-04-04 AT AT01931566T patent/ATE376000T1/de active
- 2001-04-04 JP JP2001575649A patent/JP4880854B2/ja not_active Expired - Fee Related
- 2001-04-04 DE DE50113151T patent/DE50113151D1/de not_active Expired - Lifetime
- 2001-04-04 PT PT01931566T patent/PT1276770E/pt unknown
- 2001-04-04 EP EP01931566A patent/EP1276770B1/de not_active Expired - Lifetime
- 2001-04-04 US US10/240,912 patent/US7264805B2/en not_active Expired - Lifetime
-
2007
- 2007-08-01 US US11/888,483 patent/US7820410B2/en not_active Expired - Fee Related
-
2008
- 2008-01-11 CY CY20081100043T patent/CY1107136T1/el unknown
-
2010
- 2010-09-16 US US12/883,620 patent/US9005574B2/en not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| ATE376000T1 (de) | 2007-11-15 |
| DE10016877A1 (de) | 2001-10-18 |
| JP4880854B2 (ja) | 2012-02-22 |
| EP1276770B1 (de) | 2007-10-17 |
| US20030171548A1 (en) | 2003-09-11 |
| CY1107136T1 (el) | 2012-10-24 |
| WO2001077179A1 (de) | 2001-10-18 |
| DK1276770T3 (da) | 2008-02-18 |
| EP1276770A1 (de) | 2003-01-22 |
| JP2003530126A (ja) | 2003-10-14 |
| US7264805B2 (en) | 2007-09-04 |
| US9005574B2 (en) | 2015-04-14 |
| US20080075659A1 (en) | 2008-03-27 |
| US20110008249A1 (en) | 2011-01-13 |
| DE50113151D1 (de) | 2007-11-29 |
| ES2295160T3 (es) | 2008-04-16 |
| US7820410B2 (en) | 2010-10-26 |
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