PT1246625E - Utilizacoes e composicoes de esteres de nitrato para proporcionar sedacao - Google Patents

Utilizacoes e composicoes de esteres de nitrato para proporcionar sedacao

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Publication number
PT1246625E
PT1246625E PT00986925T PT00986925T PT1246625E PT 1246625 E PT1246625 E PT 1246625E PT 00986925 T PT00986925 T PT 00986925T PT 00986925 T PT00986925 T PT 00986925T PT 1246625 E PT1246625 E PT 1246625E
Authority
PT
Portugal
Prior art keywords
sedacao
utilizations
compositions
nitrate esters
nitrate
Prior art date
Application number
PT00986925T
Other languages
English (en)
Portuguese (pt)
Inventor
Brian M Bennett
James N Reynolds
Khem Jhamandas
Gregory R J Thatcher
Original Assignee
Univ Kingston
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ Kingston filed Critical Univ Kingston
Publication of PT1246625E publication Critical patent/PT1246625E/pt

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    • C07D207/30—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members
    • C07D207/32—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • C07D207/33—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms with substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • C07D207/337—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
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    • C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
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    • C07F9/3804—Phosphonic acids [RP(=O)(OH)2]; Thiophosphonic acids ; [RP(=X1)(X2H)2(X1, X2 are each independently O, S or Se)] not used, see subgroups
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    • C07J41/0061—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring not covered by C07J41/0005 the 17-beta position being substituted by an uninterrupted chain of at least three carbon atoms which may or may not be branched, e.g. cholane or cholestane derivatives, optionally cyclised, e.g. 17-beta-phenyl or 17-beta-furyl derivatives one of the carbon atoms being part of an amide group

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PT00986925T 1999-12-29 2000-12-27 Utilizacoes e composicoes de esteres de nitrato para proporcionar sedacao PT1246625E (pt)

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CA2493156A1 (en) 2002-07-29 2004-02-05 Nitromed, Inc. Cyclooxygenase-2 selective inhibitors, compositions and methods of use
JP2005089457A (ja) * 2003-09-03 2005-04-07 Yung Shin Pharmaceutical Industry Co Ltd 骨成長を促進するまたは骨吸収を阻害するための薬剤組成物
US7498445B2 (en) 2004-05-05 2009-03-03 Renopharm Ltd. Thiazole-based nitric oxide donors capable of releasing two or more nitric oxide molecules and uses thereof
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US7189750B2 (en) * 2004-05-05 2007-03-13 Renopharm Ltd. Thiazole-based nitric oxide donors having at least two thiazole moieties and uses thereof
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US8134010B2 (en) 2004-05-05 2012-03-13 Renopharm Ltd. Thiazole-based nitric oxide donors having aryl substituent(s) and uses thereof
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AU2005284573A1 (en) * 2004-09-17 2006-03-23 Queen's University At Kingston Nitrate esters and their use for mitigating cellular damage
WO2009044902A1 (ja) 2007-10-05 2009-04-09 Kyushu Institute Of Technology 誘電泳動装置および方法
US20100035929A1 (en) * 2008-06-09 2010-02-11 Lindsley Craig W Unnatural dispyrin analogues, preparation and uses thereof
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US8957086B2 (en) * 2010-05-05 2015-02-17 The Board Of Trustees Of The University Of Illinois Compounds and methods of treating brain disorders
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