PT1222181E - Processo para a preparacao de um composto de tipo benzofurano ou benzotiofeno - Google Patents

Processo para a preparacao de um composto de tipo benzofurano ou benzotiofeno

Info

Publication number
PT1222181E
PT1222181E PT00971484T PT00971484T PT1222181E PT 1222181 E PT1222181 E PT 1222181E PT 00971484 T PT00971484 T PT 00971484T PT 00971484 T PT00971484 T PT 00971484T PT 1222181 E PT1222181 E PT 1222181E
Authority
PT
Portugal
Prior art keywords
benzofuran
benzothiophene
cyclizing
compound
chain
Prior art date
Application number
PT00971484T
Other languages
English (en)
Inventor
Thierry Schlama
Original Assignee
Rhodia Chimie Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from FR9913251A external-priority patent/FR2800064B1/fr
Priority claimed from FR0006629A external-priority patent/FR2809397B1/fr
Application filed by Rhodia Chimie Sa filed Critical Rhodia Chimie Sa
Publication of PT1222181E publication Critical patent/PT1222181E/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/77—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D307/78—Benzo [b] furans; Hydrogenated benzo [b] furans
    • C07D307/79—Benzo [b] furans; Hydrogenated benzo [b] furans with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to carbon atoms of the hetero ring
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B37/00—Reactions without formation or introduction of functional groups containing hetero atoms, involving either the formation of a carbon-to-carbon bond between two carbon atoms not directly linked already or the disconnection of two directly linked carbon atoms
    • C07B37/10—Cyclisation
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
    • C07D333/50—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
    • C07D333/52—Benzo[b]thiophenes; Hydrogenated benzo[b]thiophenes
    • C07D333/54—Benzo[b]thiophenes; Hydrogenated benzo[b]thiophenes with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to carbon atoms of the hetero ring
PT00971484T 1999-10-21 2000-10-23 Processo para a preparacao de um composto de tipo benzofurano ou benzotiofeno PT1222181E (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR9913251A FR2800064B1 (fr) 1999-10-21 1999-10-21 Procede de preparation d'un compose de type benzofurane ou benzothiophene
FR0006629A FR2809397B1 (fr) 2000-05-24 2000-05-24 Procede de preparation d'un compose de type benzofuranne ou benzothiophene

Publications (1)

Publication Number Publication Date
PT1222181E true PT1222181E (pt) 2004-04-30

Family

ID=26212419

Family Applications (1)

Application Number Title Priority Date Filing Date
PT00971484T PT1222181E (pt) 1999-10-21 2000-10-23 Processo para a preparacao de um composto de tipo benzofurano ou benzotiofeno

Country Status (13)

Country Link
US (1) US6555697B1 (pt)
EP (1) EP1222181B1 (pt)
JP (1) JP2003512365A (pt)
CN (1) CN1200935C (pt)
AT (1) ATE256118T1 (pt)
AU (1) AU1033101A (pt)
BR (1) BR0014810A (pt)
CA (1) CA2387724C (pt)
DE (1) DE60007164T2 (pt)
ES (1) ES2213050T3 (pt)
HU (1) HUP0203205A3 (pt)
PT (1) PT1222181E (pt)
WO (1) WO2001029019A1 (pt)

Families Citing this family (23)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6921827B2 (en) * 2000-11-27 2005-07-26 Eli Lilly And Company Process for preparing 3-aryl-benzo{b} thiophenes
IL146389A0 (en) 2001-11-08 2002-07-25 Isp Finetech Ltd Process for the preparation of dronedarone
DE10237819A1 (de) * 2002-08-19 2004-03-04 Bayer Ag 5-Nitrobenzofurane
US6960669B2 (en) * 2003-09-10 2005-11-01 Crompton Co./Cie Utilization of phosphorus pentasulfide in thionylations using phase transfer catalysis
FR2914643B1 (fr) * 2007-04-06 2009-06-05 Finorga Soc Par Actions Simpli Procede de preparation du 2-(n-butyl)-5-nitrobenzofurane
FR2915482B1 (fr) * 2007-04-27 2009-11-27 Finorga Procede de preparation du 2-(n-butyl)-5-nitrobenzofurane.
TW201107303A (en) 2009-05-27 2011-03-01 Sanofi Aventis Process for the production of benzofurans
UY32657A (es) 2009-05-27 2010-12-31 Sanofi Aventis Procedimiento para la fabricación de productos intermedios de dronedarona
FR2958290B1 (fr) 2010-03-30 2012-10-19 Sanofi Aventis Procede de preparation de derives de sulfonamido-benzofurane
HUP1000330A2 (en) 2010-06-18 2011-12-28 Sanofi Sa Process for the preparation of dronedarone and the novel intermediates
WO2012032545A1 (en) 2010-09-08 2012-03-15 Cadila Healthcare Limited Processes for preparing dronedarone and its intermediates
WO2012120544A2 (en) 2011-03-10 2012-09-13 Sun Pharmaceutical Industries Ltd. PROCESS FOR N-[2-n-BUTYL-3-[4-[3-(DI-n-BUTYLAMINO) PROPOXY]ENZOYL]BENZOFURAN-5-YL]METHANESULFONAMIDE HYDROCHLORIDE
HUP1100167A2 (en) 2011-03-29 2012-11-28 Sanofi Sa Process for preparation of dronedarone by mesylation
HUP1100165A2 (en) 2011-03-29 2012-12-28 Sanofi Sa Process for preparation of dronedarone by n-butylation
FR2983198B1 (fr) 2011-11-29 2013-11-15 Sanofi Sa Procede de preparation de derives de 5-amino-benzoyl-benzofurane
EP2617718A1 (en) 2012-01-20 2013-07-24 Sanofi Process for preparation of dronedarone by the use of dibutylaminopropanol reagent
US9221778B2 (en) 2012-02-13 2015-12-29 Sanofi Process for preparation of dronedarone by removal of hydroxyl group
US9249119B2 (en) 2012-02-14 2016-02-02 Sanofi Process for the preparation of dronedarone by oxidation of a sulphenyl group
US9382223B2 (en) 2012-02-22 2016-07-05 Sanofi Process for preparation of dronedarone by oxidation of a hydroxyl group
WO2013178337A1 (en) 2012-05-31 2013-12-05 Sanofi Process for preparation of dronedarone by grignard reaction
CN108675972B (zh) * 2018-08-01 2020-09-11 北京嘉林药业股份有限公司 一种盐酸胺碘酮中间体2-丁基苯并呋喃的制备方法
CN110483871A (zh) * 2019-08-15 2019-11-22 陈全明 一种抗压耐磨的hdpe双壁波纹管
CN114539193A (zh) * 2022-01-20 2022-05-27 海南普利制药股份有限公司 一种盐酸胺碘酮中间体的制备方法

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3577441A (en) * 1967-03-07 1971-05-04 Warner Lambert Pharmaceutical Nitro substituted benzofurans
DE3031738A1 (de) * 1980-08-22 1982-04-01 Troponwerke GmbH & Co KG, 5000 Köln Verfahren zur herstellung von benzo (b) thiophen-derivaten und ihre verwendung als zwischenprodukte
FR2665444B1 (fr) 1990-08-06 1992-11-27 Sanofi Sa Derives d'amino-benzofuranne, benzothiophene ou indole, leur procede de preparation ainsi que les compositions les contenant.
FR2800067B1 (fr) * 1999-10-21 2004-12-17 Rhodia Chimie Sa Intermediaires de fabrication d'un derive de type benzofurane ou benzothiophene nitre en position 5 et leurs utilisations

Also Published As

Publication number Publication date
US6555697B1 (en) 2003-04-29
DE60007164D1 (de) 2004-01-22
HUP0203205A3 (en) 2003-04-28
AU1033101A (en) 2001-04-30
CN1200935C (zh) 2005-05-11
CA2387724A1 (fr) 2001-04-26
BR0014810A (pt) 2002-06-11
JP2003512365A (ja) 2003-04-02
CN1382133A (zh) 2002-11-27
CA2387724C (fr) 2011-09-20
WO2001029019A1 (fr) 2001-04-26
DE60007164T2 (de) 2004-09-16
ES2213050T3 (es) 2004-08-16
EP1222181A1 (fr) 2002-07-17
ATE256118T1 (de) 2003-12-15
EP1222181B1 (fr) 2003-12-10
HUP0203205A2 (hu) 2003-03-28

Similar Documents

Publication Publication Date Title
PT1222181E (pt) Processo para a preparacao de um composto de tipo benzofurano ou benzotiofeno
PT885210E (pt) Compostos triciclicos que possuem afinidade de ligacao para receptores de melatonina sua producao e utilizacao
CL2012000651A1 (es) Compuestos intermediarios derivados de alamina; y su procedimiento de preparacion; utiles en la preparacion de derivados de maitansinoides.
ES2151819A1 (es) Difenilaminas noniladas.
ES2067466T5 (es) Dispersante.
UA71059C2 (uk) Спосіб одержання циталопраму
EA199900141A1 (ru) Цветообразующая композиция, содержащая реагент, включающий пирогаллольные структурные фрагменты, соль железа (ii) и органическую кислоту
CA2527059A1 (en) Process for arylamine production
EA200200098A1 (ru) Ароматические сложные эфиры для маркировки или мечения нефтепродуктов
EA200601622A1 (ru) Машина и способ транспортировки стрелок
MX9203853A (es) Asfalto substancialmente exento de solvente y metodo relacionado con el mismo.
IL173920A0 (en) Method and apparatus for wet oxidation of sludge
NO20006443D0 (no) Fremgangsmåte for fremstilling av eventuelt substituerte p- hydroksymandelforbindelser
BR0008140A (pt) Composição polifenólica, e, processo para controlar substâncias viscosas
ATE407175T1 (de) Oberflächenmodifikatoren
ATE304004T1 (de) Verfahren zur herstellung von 2-alkyl-3- aminothiophen derivate und 3-aminothiophen derivate
ATE304001T1 (de) Verfahren zur herstellung von 2-alkyl-3-aryl- und heteroaryloxaziridinen und neue 2-alkyl-3- aryloxaziridine
DE60104394D1 (de) Verfahren zur herstellung von quinolylacrylonitrilen and deren zwischenprodukten
DE60112009D1 (de) Verfahren zur Herstellung von 3-Arylbenzofuran-2-onen
ATE365704T1 (de) 1-acetoxy-3-(substituiertes phenyl) propen- verbindungen verwendbar als zwischenmaterial 1
DE69911453D1 (de) Verfahren zur demethoxycarbonylisierung von porphirinicverbindungen, wie pheophorbiderivate
BR0000481B1 (pt) Processo para a adição de uma função azida a um composto orgânico.
BR0215075A (pt) Composição para impressão em materiais de registro
ES2066981T3 (es) Composiciones para recubrimiento que contienen catalizadores de 1,3-dialquilimidazol-2-tiona.
DK71490D0 (da) En fremgangsmaade til fremstilling af organiske forbindelser