PT1156798E - Compostos derivados de felbamato - Google Patents
Compostos derivados de felbamatoInfo
- Publication number
- PT1156798E PT1156798E PT00907199T PT00907199T PT1156798E PT 1156798 E PT1156798 E PT 1156798E PT 00907199 T PT00907199 T PT 00907199T PT 00907199 T PT00907199 T PT 00907199T PT 1156798 E PT1156798 E PT 1156798E
- Authority
- PT
- Portugal
- Prior art keywords
- felbamato
- felbamate
- derivative compounds
- derivatives
- treat
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D265/00—Heterocyclic compounds containing six-membered rings having one nitrogen atom and one oxygen atom as the only ring hetero atoms
- C07D265/04—1,3-Oxazines; Hydrogenated 1,3-oxazines
- C07D265/06—1,3-Oxazines; Hydrogenated 1,3-oxazines not condensed with other rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/08—Antiepileptics; Anticonvulsants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/08—Vasodilators for multiple indications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C271/00—Derivatives of carbamic acids, i.e. compounds containing any of the groups, the nitrogen atom not being part of nitro or nitroso groups
- C07C271/06—Esters of carbamic acids
- C07C271/08—Esters of carbamic acids having oxygen atoms of carbamate groups bound to acyclic carbon atoms
- C07C271/10—Esters of carbamic acids having oxygen atoms of carbamate groups bound to acyclic carbon atoms with the nitrogen atoms of the carbamate groups bound to hydrogen atoms or to acyclic carbon atoms
- C07C271/12—Esters of carbamic acids having oxygen atoms of carbamate groups bound to acyclic carbon atoms with the nitrogen atoms of the carbamate groups bound to hydrogen atoms or to acyclic carbon atoms to hydrogen atoms or to carbon atoms of unsubstituted hydrocarbon radicals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D263/00—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings
- C07D263/02—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings
- C07D263/08—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
- C07D263/16—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D263/18—Oxygen atoms
- C07D263/20—Oxygen atoms attached in position 2
- C07D263/24—Oxygen atoms attached in position 2 with hydrocarbon radicals, substituted by oxygen atoms, attached to other ring carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D265/00—Heterocyclic compounds containing six-membered rings having one nitrogen atom and one oxygen atom as the only ring hetero atoms
- C07D265/04—1,3-Oxazines; Hydrogenated 1,3-oxazines
- C07D265/06—1,3-Oxazines; Hydrogenated 1,3-oxazines not condensed with other rings
- C07D265/08—1,3-Oxazines; Hydrogenated 1,3-oxazines not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
- C07D265/10—1,3-Oxazines; Hydrogenated 1,3-oxazines not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with oxygen atoms directly attached to ring carbon atoms
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Cardiology (AREA)
- Biomedical Technology (AREA)
- Neurosurgery (AREA)
- Heart & Thoracic Surgery (AREA)
- Neurology (AREA)
- Vascular Medicine (AREA)
- Pain & Pain Management (AREA)
- Urology & Nephrology (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Compounds Of Iron (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Hard Magnetic Materials (AREA)
- Paper (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US11925499P | 1999-02-09 | 1999-02-09 | |
| US13688199P | 1999-06-01 | 1999-06-01 | |
| US13720499P | 1999-06-02 | 1999-06-02 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| PT1156798E true PT1156798E (pt) | 2003-11-28 |
Family
ID=27382271
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PT00907199T PT1156798E (pt) | 1999-02-09 | 2000-02-08 | Compostos derivados de felbamato |
Country Status (13)
| Country | Link |
|---|---|
| US (3) | US6538024B1 (pt) |
| EP (1) | EP1156798B1 (pt) |
| JP (1) | JP2002536409A (pt) |
| AT (1) | ATE244564T1 (pt) |
| AU (1) | AU771936B2 (pt) |
| CA (1) | CA2360258A1 (pt) |
| DE (1) | DE60003791T2 (pt) |
| DK (1) | DK1156798T3 (pt) |
| ES (1) | ES2197078T3 (pt) |
| MX (1) | MXPA01007968A (pt) |
| NZ (1) | NZ513319A (pt) |
| PT (1) | PT1156798E (pt) |
| WO (1) | WO2000047202A1 (pt) |
Families Citing this family (46)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2003532672A (ja) * | 2000-05-05 | 2003-11-05 | ユニバーシティ オブ バージニア パテント ファウンデーション | フェルバマート誘導化合物 |
| JP2004517881A (ja) * | 2000-10-25 | 2004-06-17 | ユニバーシティ オブ バージニア パテント ファウンデーション | 置換フェルバメート誘導化合物 |
| US20030166648A1 (en) * | 2002-11-01 | 2003-09-04 | Macdonald Timothy L | Felbamate derived compounds |
| WO2005121249A1 (de) | 2004-06-08 | 2005-12-22 | Lanxess Deutschland Gmbh | Polyamid-formmassen mit verbesserter fliessfähigkeit |
| KR100874996B1 (ko) | 2004-06-08 | 2008-12-19 | 란세스 도이치란트 게엠베하 | 열가소성 폴리에스테르를 기재로 하는 유동성이 개선된성형 화합물 |
| MX2007003278A (es) * | 2004-09-16 | 2007-10-08 | Johnson & Johnson | Uso de 2-fenil-1,2-etanodiol-(id) carbamatos para tratar epileptogenesis y epilepsia. |
| CN101163699A (zh) * | 2005-04-21 | 2008-04-16 | 美邦特保健有限公司 | 二氨甲酸酯化合物的合成方法及形成其的中间体 |
| US20070021501A1 (en) * | 2005-07-12 | 2007-01-25 | Twyman Roy E | Methods of treating epileptogenesis |
| DE102006020984A1 (de) * | 2006-05-04 | 2007-11-08 | Lanxess Deutschland Gmbh | Leichtbauteil in Hybridbauweise |
| DE102007006493A1 (de) * | 2007-02-09 | 2008-08-14 | Lanxess Deutschland Gmbh | Leichtbauteil in Hybridbauweise |
| WO2009129181A1 (en) * | 2008-04-14 | 2009-10-22 | Concert Pharmaceuticals Inc. | Propanediol-dicarbamate derivatives |
| DE102008032205A1 (de) | 2008-07-09 | 2010-01-14 | Lanxess Deutschland Gmbh | Fließverbesserte Thermoplasten |
| DE202008015399U1 (de) | 2008-11-19 | 2010-04-08 | Lanxess Deutschland Gmbh | Dachstruktur |
| DE202008015397U1 (de) | 2008-11-19 | 2010-04-22 | Lanxess Deutschland Gmbh | Säulenstruktur |
| DE202008015395U1 (de) | 2008-11-19 | 2010-04-22 | Lanxess Deutschland Gmbh | Vorderwagenstruktur |
| DE202008015391U1 (de) | 2008-11-19 | 2010-04-22 | Lanxess Deutschland Gmbh | Türen- und Klappenstrukturen |
| DE102008058224A1 (de) | 2008-11-19 | 2010-05-20 | Lanxess Deutschland Gmbh | Leichtbauteil in Hybridbauweise |
| DE202008015398U1 (de) | 2008-11-19 | 2010-04-08 | Lanxess Deutschland Gmbh | Ölwanne |
| DE202008015396U1 (de) | 2008-11-19 | 2010-04-08 | Lanxess Deutschland Gmbh | Fahrwerkstruktur |
| DE102008058225A1 (de) * | 2008-11-19 | 2010-07-08 | Lanxess Deutschland Gmbh | Leichtbauteil in Hybridbauweise |
| DE202008015392U1 (de) | 2008-11-19 | 2010-04-08 | Lanxess Deutschland Gmbh | Pedalstruktur |
| DE202008015401U1 (de) | 2008-11-19 | 2010-04-08 | Lanxess Deutschland Gmbh | Sitzstrukturen |
| DE202008015400U1 (de) | 2008-11-19 | 2010-04-08 | Lanxess Deutschland Gmbh | Instrumententafel |
| DE202008015394U1 (de) | 2008-11-19 | 2010-04-08 | Lanxess Deutschland Gmbh | Längsträgerstruktur |
| DE102009005763A1 (de) | 2009-01-23 | 2010-07-29 | Lanxess Deutschland Gmbh | Rahmenseitenteil einer Kraftfahrzeug Karosserie |
| EP2233519B1 (de) | 2009-03-27 | 2011-08-31 | LANXESS Deutschland GmbH | Glühdrahtbeständige Polyester |
| DE102009020090A1 (de) | 2009-05-06 | 2010-11-11 | Lanxess Deutschland Gmbh | Reduktion des Einflusses der Wasseraufnahme auf die elektrische Leitfähigkeit von elektrisch leitfähigen Polyamid-Formmassen |
| DE102009034767A1 (de) | 2009-07-25 | 2011-01-27 | Lanxess Deutschland Gmbh & Co. Kg | Organoblechstrukturbauteil |
| US7964594B1 (en) * | 2009-12-10 | 2011-06-21 | Hoffmann-La Roche Inc. | Amino oxazine derivatives |
| UA103272C2 (uk) * | 2009-12-11 | 2013-09-25 | Ф. Хоффманн-Ля Рош Аг | 2-аміно-5,5-дифтор-5,6-дигідро-4h-оксазини як інгібітори bace1 і/або bace2 |
| PL2365028T3 (pl) | 2010-03-10 | 2013-03-29 | Lanxess Deutschland Gmbh | Związki zawierające ugrupowania -N=C=N- do zapobiegania rozkładowi termicznemu poli(tereftalanów alkilenowych) zawierających dialkilofosfiniany metali w stopach |
| PL2365030T3 (pl) | 2010-03-10 | 2013-02-28 | Lanxess Deutschland Gmbh | Związki zawierające ugrupowania -N=C=N- do zapobiegania rozkładowi termicznemu poli(tereftalanów alkilenowych) zawierających dialkilofosfiniany metali w stopie |
| DE102010053483A1 (de) | 2010-12-04 | 2012-06-06 | Lanxess Deutschland Gmbh | =N=C=N- enthaltende Verbindung zur Verhinderung des thermischen Abbaus in Schmelzen |
| ES2433107T3 (es) | 2010-12-13 | 2013-12-09 | Lanxess Deutschland Gmbh | Procedimiento para la optimización del comportamiento de cristalización de masas moldeables de poliéster |
| EP2465896A1 (de) | 2010-12-14 | 2012-06-20 | LANXESS Deutschland GmbH | Polyester Zusammensetzungen |
| US20140178479A1 (en) * | 2011-08-12 | 2014-06-26 | Perosphere, Inc. | Concentrated Felbamate Formulations for Parenteral Administration |
| EP2818297B1 (de) | 2013-06-25 | 2016-08-10 | LANXESS Deutschland GmbH | Spritzgießverfahren |
| IN2014DE03298A (pt) | 2013-11-27 | 2015-09-25 | Lanxess Deutschland Gmbh | |
| EP2878625A1 (de) | 2013-11-27 | 2015-06-03 | LANXESS Deutschland GmbH | Polyester Zusammensetzungen |
| HUE057170T2 (hu) | 2013-11-27 | 2022-04-28 | Lanxess Deutschland Gmbh | Poliészter-kompozíciók alkalmazása |
| DE102014000612A1 (de) | 2014-01-18 | 2015-07-23 | Lanxess Deutschland Gmbh | Polyester Zusammensetzungen |
| HUE032705T2 (en) | 2013-11-27 | 2017-10-30 | Lanxess Deutschland Gmbh | Polyester compositions |
| DE102014000613A1 (de) | 2014-01-18 | 2015-07-23 | Lanxess Deutschland Gmbh | Polyester Zusammensetzungen |
| ES2767296T3 (es) | 2013-11-28 | 2020-06-17 | Lanxess Deutschland Gmbh | Composiciones de poliamida |
| EP2915841A1 (de) | 2014-03-04 | 2015-09-09 | LANXESS Deutschland GmbH | Polyester Zusammensetzung |
| EP2942367B1 (de) | 2014-05-05 | 2018-07-11 | LANXESS Deutschland GmbH | Polyester Zusammensetzungen |
Family Cites Families (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US2884444A (en) * | 1956-01-13 | 1959-04-28 | Carter Prod Inc | 2-phenyl-1,3 propane diol dicarbamate |
| US4161582A (en) * | 1976-11-22 | 1979-07-17 | Hoffman-La Roche Inc. | Process to produce oxazinomycin |
| US4384115A (en) * | 1981-12-14 | 1983-05-17 | The Dow Chemical Company | Process for preparing tetrahydro-1,3-oxazin-2-ones |
| US4868327A (en) | 1987-06-03 | 1989-09-19 | Carter-Wallace, Inc. | Synthesis of 2-phenyl-1,3-propanediol |
| US4978680A (en) | 1989-09-26 | 1990-12-18 | Carter-Wallace, Inc. | Method for the prevention and control of epileptic seizure |
| US5082861A (en) | 1989-09-26 | 1992-01-21 | Carter-Wallace, Inc. | Method for the prevention and control of epileptic seizure associated with complex partial seizures |
| US5292772A (en) | 1989-09-26 | 1994-03-08 | Carter-Wallace, Inc. | Method for the prevention and control of epileptic seizure associated with Lennox-Gastaut syndrome |
| US5055489A (en) | 1990-05-04 | 1991-10-08 | Carter-Wallace, Inc. | Method for the prevention and control of hypoxic damage resulting from cerebral ischemic events |
| AU5159393A (en) * | 1992-09-18 | 1994-04-12 | Schering Corporation | Process for preparing felbamate, 2-phenyl-1,3-propanediol and intermediates |
| US5462966A (en) | 1993-10-15 | 1995-10-31 | Carter-Wallace Inc. | Methods for the prevention and control of cellular damage resulting from coronary artery occlusion-reperfusion |
| US5492930A (en) * | 1994-04-25 | 1996-02-20 | Schering Corporation | Method and formulation for treating CNS disorders |
| US5728728A (en) | 1996-04-10 | 1998-03-17 | Kozachuk; Walter E. | Methods of providing neuroprotection |
-
2000
- 2000-02-08 AT AT00907199T patent/ATE244564T1/de not_active IP Right Cessation
- 2000-02-08 NZ NZ513319A patent/NZ513319A/en unknown
- 2000-02-08 ES ES00907199T patent/ES2197078T3/es not_active Expired - Lifetime
- 2000-02-08 EP EP00907199A patent/EP1156798B1/en not_active Expired - Lifetime
- 2000-02-08 DE DE60003791T patent/DE60003791T2/de not_active Expired - Fee Related
- 2000-02-08 MX MXPA01007968A patent/MXPA01007968A/es not_active IP Right Cessation
- 2000-02-08 CA CA002360258A patent/CA2360258A1/en not_active Abandoned
- 2000-02-08 PT PT00907199T patent/PT1156798E/pt unknown
- 2000-02-08 JP JP2000598154A patent/JP2002536409A/ja active Pending
- 2000-02-08 WO PCT/US2000/003147 patent/WO2000047202A1/en active IP Right Grant
- 2000-02-08 DK DK00907199T patent/DK1156798T3/da active
- 2000-02-08 AU AU28734/00A patent/AU771936B2/en not_active Ceased
-
2001
- 2001-08-09 US US09/925,224 patent/US6538024B1/en not_active Expired - Fee Related
- 2001-12-17 US US10/023,059 patent/US6599935B2/en not_active Expired - Fee Related
-
2003
- 2003-06-06 US US10/456,117 patent/US6759402B2/en not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| DE60003791T2 (de) | 2004-02-05 |
| US20020156070A1 (en) | 2002-10-24 |
| JP2002536409A (ja) | 2002-10-29 |
| WO2000047202A1 (en) | 2000-08-17 |
| NZ513319A (en) | 2003-08-29 |
| ES2197078T3 (es) | 2004-01-01 |
| US6538024B1 (en) | 2003-03-25 |
| AU771936B2 (en) | 2004-04-08 |
| EP1156798A4 (en) | 2002-07-17 |
| US20030229086A1 (en) | 2003-12-11 |
| EP1156798B1 (en) | 2003-07-09 |
| MXPA01007968A (es) | 2003-07-14 |
| DK1156798T3 (da) | 2003-11-03 |
| CA2360258A1 (en) | 2000-08-17 |
| US6759402B2 (en) | 2004-07-06 |
| DE60003791D1 (de) | 2003-08-14 |
| ATE244564T1 (de) | 2003-07-15 |
| AU2873400A (en) | 2000-08-29 |
| EP1156798A1 (en) | 2001-11-28 |
| US6599935B2 (en) | 2003-07-29 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| PT1156798E (pt) | Compostos derivados de felbamato | |
| TR200201505T2 (tr) | Terapötik maddeler olarak pirazolopirimidinler | |
| PA8481301A1 (es) | Derivados de 4,4-biarilpiperidina | |
| ECSP003610A (es) | Pirimidina-2,4,6 trionas inhibidores de metaloproteinas | |
| ATE277929T1 (de) | Immunsuppressive wirkungen von pteridinderivaten | |
| GT200100137A (es) | Pro-drogas de derivados de 4-fenil-piridina. | |
| MXPA04006184A (es) | Compuestos derivados de 1h-pirazolilo, para el uso en enfermedades asociadas con el receptor 5-ht2c. | |
| HK1057899A1 (en) | Arylmethylamine derivatives for use as tryptase inhibitors | |
| EA200701782A3 (ru) | Производные азаспироалканов в качестве ингибиторов металлопротеаз | |
| TR199901904T2 (xx) | 3-piridil enantiyomerleri ve bunlar�n analjezik olarak kullan�lmas�. | |
| MY119375A (en) | Treatment of tinnitus using neuroprotective agents | |
| EA200201276A1 (ru) | Производные арилметиламина для использования в качестве ингибиторов триптазы | |
| ATE325610T1 (de) | Xanthinderivative zur behandlung von hirnischämie | |
| PA8487701A1 (es) | Derivados de 3,3-biarilpiperidina y 2,2-biarilmorfolina | |
| DK1032556T3 (da) | Farmaceutisk aktive forbindelser og anvendelsesfremgangsmåder | |
| NO20014240D0 (no) | C16-umettede FP-selektive prostaglandinanaloger | |
| DE69931378D1 (de) | Chinazolin derivate und therapeutische verwendungen davon | |
| ECSP003590A (es) | Compuestos calcioliticos | |
| CA2362833A1 (en) | Phenylalaninol derivatives | |
| UY27009A1 (es) | Nuevos heteroaromatos | |
| CY1106576T1 (el) | Υποκατεστημενα παραγωγα 2-πυρρολιδιν-2-υλ-1h-ινδολης για τη θεραπεια ημικρανιας | |
| ES2118248T3 (es) | Esteres y amidas de 9-cloro-prostaglandina y su empleo para preparar medicamentos. | |
| MXPA03003677A (es) | Compuestos derivados de felbamato sustituidos. | |
| YU19302A (sh) | 4-benzilaminohinolin konjugovan žučnom kiselinom i njegovi heteroanalozi, postupak za njihovu proizvodnju, lekovi koji sadrže ta jedinjenja i njihova primena | |
| UY27453A1 (es) | Procedimiento para preparar derivados de heterocicloalquilsulfonilpirazol |