PT1117999E - Caracterizacao de polipeptidos por clivagem e por espectrometria de massa - Google Patents

Caracterizacao de polipeptidos por clivagem e por espectrometria de massa

Info

Publication number
PT1117999E
PT1117999E PT99947722T PT99947722T PT1117999E PT 1117999 E PT1117999 E PT 1117999E PT 99947722 T PT99947722 T PT 99947722T PT 99947722 T PT99947722 T PT 99947722T PT 1117999 E PT1117999 E PT 1117999E
Authority
PT
Portugal
Prior art keywords
mass spectrometry
polypeptide
polipeptidos
cliving
characterization
Prior art date
Application number
PT99947722T
Other languages
English (en)
Inventor
Gunter Schmidt
Andrew Hugin Thompson
Original Assignee
Xzillion Gmbh & Co Kg
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Xzillion Gmbh & Co Kg filed Critical Xzillion Gmbh & Co Kg
Publication of PT1117999E publication Critical patent/PT1117999E/pt

Links

Classifications

    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6803General methods of protein analysis not limited to specific proteins or families of proteins
    • G01N33/6848Methods of protein analysis involving mass spectrometry
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K1/00General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/12General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length by hydrolysis, i.e. solvolysis in general
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6803General methods of protein analysis not limited to specific proteins or families of proteins
    • G01N33/6842Proteomic analysis of subsets of protein mixtures with reduced complexity, e.g. membrane proteins, phosphoproteins, organelle proteins
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10TTECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T436/00Chemistry: analytical and immunological testing
    • Y10T436/24Nuclear magnetic resonance, electron spin resonance or other spin effects or mass spectrometry

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Chemical & Material Sciences (AREA)
  • Physics & Mathematics (AREA)
  • Hematology (AREA)
  • Biophysics (AREA)
  • Biomedical Technology (AREA)
  • Urology & Nephrology (AREA)
  • Bioinformatics & Computational Biology (AREA)
  • Immunology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biochemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Analytical Chemistry (AREA)
  • Microbiology (AREA)
  • Cell Biology (AREA)
  • Biotechnology (AREA)
  • Organic Chemistry (AREA)
  • Food Science & Technology (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Genetics & Genomics (AREA)
  • Spectroscopy & Molecular Physics (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Other Investigation Or Analysis Of Materials By Electrical Means (AREA)
  • Peptides Or Proteins (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
PT99947722T 1998-10-01 1999-10-01 Caracterizacao de polipeptidos por clivagem e por espectrometria de massa PT1117999E (pt)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GBGB9821393.7A GB9821393D0 (en) 1998-10-01 1998-10-01 Protein profiling 2

Publications (1)

Publication Number Publication Date
PT1117999E true PT1117999E (pt) 2003-06-30

Family

ID=10839813

Family Applications (1)

Application Number Title Priority Date Filing Date
PT99947722T PT1117999E (pt) 1998-10-01 1999-10-01 Caracterizacao de polipeptidos por clivagem e por espectrometria de massa

Country Status (16)

Country Link
US (1) US6846679B1 (pt)
EP (1) EP1117999B1 (pt)
JP (1) JP3730121B2 (pt)
CN (1) CN1411555A (pt)
AT (1) ATE232300T1 (pt)
AU (1) AU768902B2 (pt)
CA (1) CA2344642C (pt)
DE (1) DE69905265T2 (pt)
DK (1) DK1117999T3 (pt)
ES (1) ES2192080T3 (pt)
GB (1) GB9821393D0 (pt)
IL (2) IL142314A0 (pt)
NO (1) NO20011552L (pt)
NZ (1) NZ510873A (pt)
PT (1) PT1117999E (pt)
WO (1) WO2000020870A1 (pt)

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US6003511A (en) 1996-11-18 1999-12-21 Medlis Corp. Respiratory circuit terminal for a unilimb respiratory device
CA2411126A1 (en) 2000-06-09 2001-12-13 Mds Proteomics, Inc. Labeling of proteomic samples during proteolysis for quantitation and sample multiplexing
JP2004503780A (ja) 2000-06-12 2004-02-05 ユニバーシティ オブ ワシントン リンペプチドの選択的標識および単離ならびにプロテオーム分析への適用
GB0014342D0 (en) * 2000-06-13 2000-08-02 Scient Analysis Instr Limited Method of analysis
JP2002168869A (ja) * 2000-12-05 2002-06-14 Sumitomo Chem Co Ltd ペプチドのアミノ酸配列の決定方法
JP4604345B2 (ja) * 2000-12-21 2011-01-05 住友化学株式会社 タンパク質のn末端のアミノ酸配列決定方法
US20020106700A1 (en) * 2001-02-05 2002-08-08 Foote Robert S. Method for analyzing proteins
DE10108892B4 (de) * 2001-02-23 2005-08-18 Graffinity Pharmaceuticals Ag Synthesevorrichtung und Verfahren zu deren Herstellung
EP1267170A1 (en) * 2001-06-07 2002-12-18 Xzillion GmbH & CO.KG Method for characterising polypeptides
EP1265072A1 (en) * 2001-06-07 2002-12-11 Xzillion GmbH & CO.KG Method for characterising polypeptides
JP4163103B2 (ja) * 2001-06-07 2008-10-08 エレクトロフォレティクス リミテッド ポリペプチドの特徴分析方法
US20030064359A1 (en) * 2001-09-21 2003-04-03 Joel Lanoix Preparation of highly-purified plasma membranes
US7717109B2 (en) 2001-09-24 2010-05-18 F-Concepts Llc Breathing systems with post-inspiratory valve fresh gas flow input, components for implementing same, and methods of use
CN100512910C (zh) 2001-09-24 2009-07-15 福永敦翁福 具有非习知呼吸导管的呼吸回路及用以最佳利用新鲜气体的系统及方法
US20050064422A1 (en) * 2001-11-29 2005-03-24 Barnidge David R Polypeptide quantitation
EP2317307B1 (en) 2002-02-14 2013-11-20 Ajinomoto Co., Inc. Method of analyzing amino- and/or imino-functional compounds, and analytical reagent
WO2003087839A1 (en) * 2002-04-04 2003-10-23 Xzillion Gmbh & Co. Kg Method for characterising analytes
CN1314968C (zh) * 2004-03-11 2007-05-09 复旦大学 痕量多肽或蛋白质富集及其直接分析方法
US20060249668A1 (en) * 2005-05-05 2006-11-09 Palo Alto Research Center Incorporated Automatic detection of quality spectra
US7230235B2 (en) * 2005-05-05 2007-06-12 Palo Alto Research Center Incorporated Automatic detection of quality spectra
GB0515323D0 (en) 2005-07-26 2005-08-31 Electrophoretics Ltd Mass labels
GB0518585D0 (en) 2005-09-12 2005-10-19 Electrophoretics Ltd Mass labels
US20110053196A1 (en) * 2006-02-08 2011-03-03 Nec Corporation Method for modifying a peptide and a method for identifying a peptide
CN101379402A (zh) * 2006-02-08 2009-03-04 日本电气株式会社 一种裂解肽的c端肽键的方法和确定肽的c端氨基酸序列的方法
US20080319678A1 (en) * 2006-02-15 2008-12-25 University Of Virginia Patent Foundation Mass Tagging for Quantitative Analysis of Biomolecules using 13C Labeled Phenylisocyanate
WO2012156764A1 (en) 2011-05-18 2012-11-22 Rudjer Boskovic Institute Method of detection of amino acid sequence and/or identification of peptides and proteins, by use of a new derivatization reagent and synthesis of 5-formyl-benzene-1,3-disulphonic acid as derivatization reagent
CN111208237B (zh) * 2018-11-21 2021-12-24 中国科学院大连化学物理研究所 基于肽段c末端化学衍生提高质谱碎裂效率和响应的方法

Family Cites Families (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB2168478A (en) * 1984-11-26 1986-06-18 Scan Limited M Analysis of protein etc using mass spectrometry
US5792664A (en) * 1992-05-29 1998-08-11 The Rockefeller University Methods for producing and analyzing biopolymer ladders
ATE427493T1 (de) * 1992-05-29 2009-04-15 Univ Rockefeller Verfahren zur bestimmung der folge von peptiden unter verwendung eines massenspektrometers
US5470703A (en) * 1992-10-21 1995-11-28 Shimadzu Corporation Method for peptide C-terminal fragment sequence analysis and apparatus for collecting peptide fragment
JPH06172380A (ja) * 1992-12-04 1994-06-21 Shimadzu Corp ペプチドフラグメント分取装置
EP1347493A3 (en) * 1993-05-28 2005-11-23 Baylor College Of Medicine Method and apparatus for desorption and ionization of analytes
US6017693A (en) * 1994-03-14 2000-01-25 University Of Washington Identification of nucleotides, amino acids, or carbohydrates by mass spectrometry
US5827659A (en) * 1995-05-19 1998-10-27 Perseptive Biosystems, Inc. Methods and apparatus for sequencing polymers using mass spectrometry
US5869240A (en) * 1995-05-19 1999-02-09 Perseptive Biosystems, Inc. Methods and apparatus for sequencing polymers with a statistical certainty using mass spectrometry
WO1996036986A1 (en) * 1995-05-19 1996-11-21 Perseptive Biosystems, Inc. Methods and apparatus for sequencing polymers with a statistical certainty using mass spectrometry
US6245331B1 (en) * 1997-01-02 2001-06-12 New York Univ. Medical Center Early detection of mycobacterial disease
EP1027454B1 (en) * 1997-01-23 2003-08-13 Xzillion GmbH & CO.KG Characterising polypeptides
US5824556A (en) * 1997-06-11 1998-10-20 Tarr; George E. Peptide mass ladders generated using carbon disulfide
US6379971B1 (en) * 1998-02-24 2002-04-30 Target Discovery, Inc. Methods for sequencing proteins
DE60031030T2 (de) * 1999-04-06 2007-05-10 Micromass UK Ltd., Simonsway Verfahren zur Identifizierung von Peptiden und Proteinen mittels Massenspektromterie

Also Published As

Publication number Publication date
JP3730121B2 (ja) 2005-12-21
IL142314A0 (en) 2002-03-10
CN1411555A (zh) 2003-04-16
AU6109699A (en) 2000-04-26
WO2000020870A1 (en) 2000-04-13
DK1117999T3 (da) 2003-05-26
NO20011552D0 (no) 2001-03-27
EP1117999A1 (en) 2001-07-25
CA2344642C (en) 2004-06-22
JP2002526778A (ja) 2002-08-20
DE69905265T2 (de) 2003-11-27
CA2344642A1 (en) 2000-04-13
GB9821393D0 (en) 1998-11-25
NZ510873A (en) 2002-10-25
ATE232300T1 (de) 2003-02-15
AU768902B2 (en) 2004-01-08
EP1117999B1 (en) 2003-02-05
ES2192080T3 (es) 2003-09-16
US6846679B1 (en) 2005-01-25
IL142314A (en) 2006-07-05
NO20011552L (no) 2001-06-01
DE69905265D1 (de) 2003-03-13

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