PT1091959E - Novos derivados de pirrol-(3,4-b)quinoleina seu processo de preparacao e sua utilizacao a titulo de medicamento - Google Patents

Novos derivados de pirrol-(3,4-b)quinoleina seu processo de preparacao e sua utilizacao a titulo de medicamento

Info

Publication number
PT1091959E
PT1091959E PT00922769T PT00922769T PT1091959E PT 1091959 E PT1091959 E PT 1091959E PT 00922769 T PT00922769 T PT 00922769T PT 00922769 T PT00922769 T PT 00922769T PT 1091959 E PT1091959 E PT 1091959E
Authority
PT
Portugal
Prior art keywords
preparation process
medicinal product
pyrrol
new
quinolein
Prior art date
Application number
PT00922769T
Other languages
English (en)
Inventor
Jean-Claude Jacquesy
Marie-Paule Jouannetaud
Jean-Bernard Fourtillan
Marianne Fourtillan
Omar Karam
Fabien Zunino
Original Assignee
Besins Int Lab
Macef
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Besins Int Lab, Macef filed Critical Besins Int Lab
Publication of PT1091959E publication Critical patent/PT1091959E/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/20—Hypnotics; Sedatives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/22—Anxiolytics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
PT00922769T 1999-04-27 2000-04-27 Novos derivados de pirrol-(3,4-b)quinoleina seu processo de preparacao e sua utilizacao a titulo de medicamento PT1091959E (pt)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR9905302A FR2792937B1 (fr) 1999-04-27 1999-04-27 NOUVEAUX DERIVES DE PYRROLO-(3,4-b) QUINOLEINE, LEUR PROCEDE DE PREPARATION ET LEUR UTILISATION A TITRE DE MEDICAMENT

Publications (1)

Publication Number Publication Date
PT1091959E true PT1091959E (pt) 2003-03-31

Family

ID=9544900

Family Applications (1)

Application Number Title Priority Date Filing Date
PT00922769T PT1091959E (pt) 1999-04-27 2000-04-27 Novos derivados de pirrol-(3,4-b)quinoleina seu processo de preparacao e sua utilizacao a titulo de medicamento

Country Status (13)

Country Link
US (1) US6335346B1 (pt)
EP (1) EP1091959B1 (pt)
JP (1) JP2002543078A (pt)
CN (1) CN1182136C (pt)
AR (1) AR035988A1 (pt)
AT (1) ATE226582T1 (pt)
DE (1) DE60000646T2 (pt)
DK (1) DK1091959T3 (pt)
ES (1) ES2184712T3 (pt)
FR (1) FR2792937B1 (pt)
PT (1) PT1091959E (pt)
WO (1) WO2000064897A1 (pt)
ZA (1) ZA200100165B (pt)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
UA72611C2 (uk) * 2000-05-17 2005-03-15 Орто-Макнейл Фармацевтикал, Інк. Похідні заміщеного піролопіридинону, корисні як інгібітори фосфодіестерази
EP1534707B9 (en) 2002-06-19 2008-11-26 Janssen Pharmaceutica N.V. Substituted 2,4-dihydro-pyrrolo (3, 4-b) -quinolin-9-one derivatives useful as phosphodiesterase inhibitors
FR2898358B1 (fr) * 2006-03-08 2008-05-30 Macef Sa Association d'un antagoniste du recepteur 5ht2 et d'activateur du recepteur 5ht2 par modulation allosterique et leurs utilisations comme produits medicaux
FR2912747A1 (fr) * 2007-02-19 2008-08-22 Fourtillan Snc Derives des 1-(1-hydoxy-3-oxo-propen-1-yl)-1,2,3,3a,8,8a-hexahydro- pyrrolo[2,3-b)indoles et leur utilisation en therapeutique
EP2326645B9 (en) * 2008-07-29 2013-04-17 Aziende Chimiche Riunite Angelini Francesco A.C.R.A.F. S.p.A. Compound with serotoninergic activity, process for preparing it and pharmaceutical composition comprising it
CN104892605A (zh) * 2015-07-06 2015-09-09 渤海大学 一种吡咯并[3,4-b]喹啉-1-酮衍生物的制备方法

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2023514A1 (de) * 1970-05-14 1971-12-02 Badische Anilin- & Soda-Fabrik Ag, 6700 Ludwigshafen Verfahren zur Herstellung von 5,6-gamma-Pyridonderivaten
CA1332413C (en) 1987-06-25 1994-10-11 Kabushiki Kaisha Yakult Honsha Camptothecin derivatives and process for preparing same
US4943579A (en) 1987-10-06 1990-07-24 The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services Water soluble prodrugs of camptothecin
CA2087898A1 (en) 1992-01-24 1993-07-25 Hiroshi Akimoto Condensed heterocyclic compounds, their production and use
IT1269862B (it) 1994-05-30 1997-04-15 Indena Spa Alcaloidi da mappia foetida, loro uso e formulazioni che li contengono
JPH0873461A (ja) 1994-09-06 1996-03-19 Yakult Honsha Co Ltd 新規なカンプトテシン誘導体、その製造法および抗腫瘍剤
FR2724384B1 (fr) * 1994-09-14 1999-04-16 Cemaf Nouveaux derives de la 3,4-dihydro beta-carboline agonistes de la melatonine, leur procede de preparation et leur utilisation a titre de medicament
FR2737725B1 (fr) * 1995-08-08 1997-10-31 Valentonine Nouveaux derives acyles de la melatonine et d'analogues melatoninergiques, leur procede de preparation et leur utilisation en tant que medicament
IT1283635B1 (it) 1996-05-10 1998-04-23 Indena Spa Composti a scheletro camptotecinico isolati da mappia foetida e loro uso come sintoni per farmaci o come principi attivi

Also Published As

Publication number Publication date
ZA200100165B (en) 2001-08-03
FR2792937B1 (fr) 2001-08-10
WO2000064897A1 (fr) 2000-11-02
AR035988A1 (es) 2004-08-04
US6335346B1 (en) 2002-01-01
CN1306532A (zh) 2001-08-01
DE60000646D1 (de) 2002-11-28
DE60000646T2 (de) 2003-06-26
EP1091959A1 (fr) 2001-04-18
ES2184712T3 (es) 2003-04-16
JP2002543078A (ja) 2002-12-17
FR2792937A1 (fr) 2000-11-03
DK1091959T3 (da) 2003-02-24
CN1182136C (zh) 2004-12-29
ATE226582T1 (de) 2002-11-15
EP1091959B1 (fr) 2002-10-23

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PT1091959E (pt) Novos derivados de pirrol-(3,4-b)quinoleina seu processo de preparacao e sua utilizacao a titulo de medicamento