PT1082321E - Derivados heterociclicos que inibem o factor xa - Google Patents
Derivados heterociclicos que inibem o factor xaInfo
- Publication number
- PT1082321E PT1082321E PT99918178T PT99918178T PT1082321E PT 1082321 E PT1082321 E PT 1082321E PT 99918178 T PT99918178 T PT 99918178T PT 99918178 T PT99918178 T PT 99918178T PT 1082321 E PT1082321 E PT 1082321E
- Authority
- PT
- Portugal
- Prior art keywords
- heterocyclic derivatives
- inhibit
- factor
- relates
- antithrombotic
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
- C07D403/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GBGB9809351.1A GB9809351D0 (en) | 1998-05-02 | 1998-05-02 | Heterocyclic derivatives |
GBGB9903337.5A GB9903337D0 (en) | 1999-02-16 | 1999-02-16 | Heterocyclic derivatives |
Publications (1)
Publication Number | Publication Date |
---|---|
PT1082321E true PT1082321E (pt) | 2005-03-31 |
Family
ID=26313572
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PT99918178T PT1082321E (pt) | 1998-05-02 | 1999-04-27 | Derivados heterociclicos que inibem o factor xa |
Country Status (23)
Country | Link |
---|---|
US (2) | US6753331B1 (pt) |
EP (2) | EP1528061A1 (pt) |
JP (1) | JP2002513790A (pt) |
KR (1) | KR20010043246A (pt) |
CN (1) | CN1133634C (pt) |
AT (1) | ATE282610T1 (pt) |
AU (1) | AU754453B2 (pt) |
BR (1) | BR9910179A (pt) |
CA (1) | CA2331042A1 (pt) |
DE (1) | DE69921994T2 (pt) |
EE (1) | EE200000527A (pt) |
ES (1) | ES2232131T3 (pt) |
HK (1) | HK1034711A1 (pt) |
HU (1) | HUP0101712A3 (pt) |
IL (1) | IL139406A (pt) |
NO (1) | NO320893B1 (pt) |
NZ (1) | NZ507835A (pt) |
PL (1) | PL343706A1 (pt) |
PT (1) | PT1082321E (pt) |
SI (1) | SI1082321T1 (pt) |
SK (1) | SK16512000A3 (pt) |
TR (1) | TR200003200T2 (pt) |
WO (1) | WO1999057113A1 (pt) |
Families Citing this family (21)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
IL115420A0 (en) | 1994-09-26 | 1995-12-31 | Zeneca Ltd | Aminoheterocyclic derivatives |
GB9902989D0 (en) | 1999-02-11 | 1999-03-31 | Zeneca Ltd | Heterocyclic derivatives |
GB9914342D0 (en) * | 1999-06-19 | 1999-08-18 | Zeneca Ltd | Compound |
GB9917344D0 (en) * | 1999-07-24 | 1999-09-22 | Zeneca Ltd | Novel salt |
TWI290136B (en) | 2000-04-05 | 2007-11-21 | Daiichi Seiyaku Co | Ethylenediamine derivatives |
GB0012448D0 (en) | 2000-05-24 | 2000-07-12 | Astrazeneca Ab | New process |
CA2428784A1 (en) * | 2000-11-09 | 2002-05-16 | Astrazeneca Ab | Oral pharmaceutical composition containing a block copolymer |
GB0104752D0 (en) * | 2001-02-27 | 2001-04-18 | Astrazeneca Ab | Pharmaceutical compositions |
US7365205B2 (en) | 2001-06-20 | 2008-04-29 | Daiichi Sankyo Company, Limited | Diamine derivatives |
AU2003302238A1 (en) | 2002-12-03 | 2004-06-23 | Axys Pharmaceuticals, Inc. | 2-(2-hydroxybiphenyl-3-yl)-1h-benzoimidazole-5-carboxamidine derivatives as factor viia inhibitors |
WO2004108671A1 (en) * | 2003-06-06 | 2004-12-16 | Suven Life Sciences Limited | Substituted indoles with serotonin receptor affinity, process for their preparation and pharmaceutical compositions containing them |
US7553837B2 (en) * | 2003-08-01 | 2009-06-30 | Nippon Soda Co., Ltd. | Phenylazole compounds production process and antioxidants |
SE0400014D0 (sv) * | 2004-01-08 | 2004-01-08 | Astrazeneca Ab | Heterocyclic derivatives |
WO2007008144A1 (en) * | 2005-07-08 | 2007-01-18 | Astrazeneca Ab | Heterocyclic sulfonamide derivatives as inhibitors of factor xa |
WO2007008143A1 (en) * | 2005-07-08 | 2007-01-18 | Astrazeneca Ab | Heterocyclic sulfonamide derivatives as inhibitors of factor xa |
WO2007008145A1 (en) * | 2005-07-08 | 2007-01-18 | Astrazeneca Ab | Heterocyclic sulfonamide derivatives as inhibitors of factor xa |
CN101218227A (zh) * | 2005-07-08 | 2008-07-09 | 阿斯利康(瑞典)有限公司 | 作为因子Xa的抑制剂的杂环磺酰胺衍生物 |
ES2910071T3 (es) | 2018-03-08 | 2022-05-11 | Incyte Corp | Compuestos de aminopirazina diol como inhibidores de PI3K-Y |
WO2020010003A1 (en) | 2018-07-02 | 2020-01-09 | Incyte Corporation | AMINOPYRAZINE DERIVATIVES AS PI3K-γ INHIBITORS |
AU2020300002A1 (en) | 2019-07-01 | 2022-02-24 | Tonix Pharma Limited | Anti-CD154 antibodies and uses thereof |
JP2024503625A (ja) | 2021-01-06 | 2024-01-26 | トニックス ファーマ リミテッド | 改変された抗cd154抗体により免疫寛容を誘導する方法 |
Family Cites Families (8)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
IL115420A0 (en) * | 1994-09-26 | 1995-12-31 | Zeneca Ltd | Aminoheterocyclic derivatives |
ES2219706T3 (es) * | 1995-12-21 | 2004-12-01 | Bristol-Myers Squibb Pharma Company | Isoxazolinas, isotiazolinas y pirazolinas inhibidores del factor xa. |
GB9602166D0 (en) * | 1996-02-02 | 1996-04-03 | Zeneca Ltd | Aminoheterocyclic derivatives |
GB9602294D0 (en) | 1996-02-05 | 1996-04-03 | Zeneca Ltd | Heterocyclic compounds |
UA56197C2 (uk) | 1996-11-08 | 2003-05-15 | Зенека Лімітед | Гетероциклічні похідні |
WO1998054164A1 (en) * | 1997-05-30 | 1998-12-03 | Takeda Chemical Industries, Ltd. | Sulfonamide derivatives, their production and use |
GB9715894D0 (en) | 1997-07-29 | 1997-10-01 | Zeneca Ltd | Heterocyclic derivatives |
DE19743435A1 (de) * | 1997-10-01 | 1999-04-08 | Merck Patent Gmbh | Benzamidinderivate |
-
1999
- 1999-04-27 PT PT99918178T patent/PT1082321E/pt unknown
- 1999-04-27 JP JP2000547083A patent/JP2002513790A/ja active Pending
- 1999-04-27 PL PL99343706A patent/PL343706A1/xx not_active Application Discontinuation
- 1999-04-27 AU AU36206/99A patent/AU754453B2/en not_active Ceased
- 1999-04-27 US US09/674,559 patent/US6753331B1/en not_active Expired - Fee Related
- 1999-04-27 CA CA002331042A patent/CA2331042A1/en not_active Abandoned
- 1999-04-27 SI SI9930725T patent/SI1082321T1/xx unknown
- 1999-04-27 CN CNB99808218XA patent/CN1133634C/zh not_active Expired - Fee Related
- 1999-04-27 KR KR1020007012193A patent/KR20010043246A/ko not_active Application Discontinuation
- 1999-04-27 IL IL13940699A patent/IL139406A/en not_active IP Right Cessation
- 1999-04-27 TR TR2000/03200T patent/TR200003200T2/xx unknown
- 1999-04-27 ES ES99918178T patent/ES2232131T3/es not_active Expired - Lifetime
- 1999-04-27 WO PCT/GB1999/001308 patent/WO1999057113A1/en not_active Application Discontinuation
- 1999-04-27 HU HU0101712A patent/HUP0101712A3/hu unknown
- 1999-04-27 EE EEP200000527A patent/EE200000527A/xx unknown
- 1999-04-27 DE DE69921994T patent/DE69921994T2/de not_active Expired - Lifetime
- 1999-04-27 EP EP04022155A patent/EP1528061A1/en not_active Withdrawn
- 1999-04-27 BR BR9910179-3A patent/BR9910179A/pt not_active Application Discontinuation
- 1999-04-27 AT AT99918178T patent/ATE282610T1/de not_active IP Right Cessation
- 1999-04-27 EP EP99918178A patent/EP1082321B1/en not_active Expired - Lifetime
- 1999-04-27 NZ NZ507835A patent/NZ507835A/xx unknown
- 1999-04-27 SK SK1651-2000A patent/SK16512000A3/sk unknown
-
2000
- 2000-11-01 NO NO20005497A patent/NO320893B1/no unknown
-
2001
- 2001-07-26 HK HK01105226A patent/HK1034711A1/xx not_active IP Right Cessation
-
2004
- 2004-04-06 US US10/817,960 patent/US20040266759A1/en not_active Abandoned
Also Published As
Publication number | Publication date |
---|---|
ATE282610T1 (de) | 2004-12-15 |
KR20010043246A (ko) | 2001-05-25 |
BR9910179A (pt) | 2001-01-09 |
SK16512000A3 (sk) | 2001-05-10 |
TR200003200T2 (tr) | 2001-02-21 |
DE69921994D1 (de) | 2004-12-23 |
CN1133634C (zh) | 2004-01-07 |
NZ507835A (en) | 2003-01-31 |
IL139406A0 (en) | 2001-11-25 |
NO20005497L (no) | 2000-12-21 |
AU754453B2 (en) | 2002-11-14 |
US6753331B1 (en) | 2004-06-22 |
EP1528061A1 (en) | 2005-05-04 |
ES2232131T3 (es) | 2005-05-16 |
CN1308631A (zh) | 2001-08-15 |
JP2002513790A (ja) | 2002-05-14 |
SI1082321T1 (en) | 2005-06-30 |
PL343706A1 (en) | 2001-08-27 |
NO20005497D0 (no) | 2000-11-01 |
EP1082321A1 (en) | 2001-03-14 |
DE69921994T2 (de) | 2005-12-01 |
CA2331042A1 (en) | 1999-11-11 |
AU3620699A (en) | 1999-11-23 |
HK1034711A1 (en) | 2001-11-02 |
EE200000527A (et) | 2002-02-15 |
HUP0101712A2 (hu) | 2001-11-28 |
WO1999057113A1 (en) | 1999-11-11 |
US20040266759A1 (en) | 2004-12-30 |
EP1082321B1 (en) | 2004-11-17 |
IL139406A (en) | 2004-07-25 |
NO320893B1 (no) | 2006-02-06 |
HUP0101712A3 (en) | 2003-01-28 |
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