EE200000527A - Faktorit Xa pärssivad heterotsüklilised derivaadid - Google Patents
Faktorit Xa pärssivad heterotsüklilised derivaadidInfo
- Publication number
- EE200000527A EE200000527A EEP200000527A EEP200000527A EE200000527A EE 200000527 A EE200000527 A EE 200000527A EE P200000527 A EEP200000527 A EE P200000527A EE P200000527 A EEP200000527 A EE P200000527A EE 200000527 A EE200000527 A EE 200000527A
- Authority
- EE
- Estonia
- Prior art keywords
- heterocyclic derivatives
- inhibited
- factor
- relates
- antithrombotic
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
- C07D403/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Diabetes (AREA)
- Hematology (AREA)
- Urology & Nephrology (AREA)
- Vascular Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GBGB9809351.1A GB9809351D0 (en) | 1998-05-02 | 1998-05-02 | Heterocyclic derivatives |
GBGB9903337.5A GB9903337D0 (en) | 1999-02-16 | 1999-02-16 | Heterocyclic derivatives |
PCT/GB1999/001308 WO1999057113A1 (en) | 1998-05-02 | 1999-04-27 | Heterocyclic derivatives which inhibit factor xa |
Publications (1)
Publication Number | Publication Date |
---|---|
EE200000527A true EE200000527A (et) | 2002-02-15 |
Family
ID=26313572
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
EEP200000527A EE200000527A (et) | 1998-05-02 | 1999-04-27 | Faktorit Xa pärssivad heterotsüklilised derivaadid |
Country Status (23)
Country | Link |
---|---|
US (2) | US6753331B1 (et) |
EP (2) | EP1082321B1 (et) |
JP (1) | JP2002513790A (et) |
KR (1) | KR20010043246A (et) |
CN (1) | CN1133634C (et) |
AT (1) | ATE282610T1 (et) |
AU (1) | AU754453B2 (et) |
BR (1) | BR9910179A (et) |
CA (1) | CA2331042A1 (et) |
DE (1) | DE69921994T2 (et) |
EE (1) | EE200000527A (et) |
ES (1) | ES2232131T3 (et) |
HK (1) | HK1034711A1 (et) |
HU (1) | HUP0101712A3 (et) |
IL (1) | IL139406A (et) |
NO (1) | NO320893B1 (et) |
NZ (1) | NZ507835A (et) |
PL (1) | PL343706A1 (et) |
PT (1) | PT1082321E (et) |
SI (1) | SI1082321T1 (et) |
SK (1) | SK16512000A3 (et) |
TR (1) | TR200003200T2 (et) |
WO (1) | WO1999057113A1 (et) |
Families Citing this family (21)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
IL115420A0 (en) | 1994-09-26 | 1995-12-31 | Zeneca Ltd | Aminoheterocyclic derivatives |
GB9902989D0 (en) | 1999-02-11 | 1999-03-31 | Zeneca Ltd | Heterocyclic derivatives |
GB9914342D0 (en) * | 1999-06-19 | 1999-08-18 | Zeneca Ltd | Compound |
GB9917344D0 (en) * | 1999-07-24 | 1999-09-22 | Zeneca Ltd | Novel salt |
TWI290136B (en) | 2000-04-05 | 2007-11-21 | Daiichi Seiyaku Co | Ethylenediamine derivatives |
GB0012448D0 (en) | 2000-05-24 | 2000-07-12 | Astrazeneca Ab | New process |
MXPA03004112A (es) * | 2000-11-09 | 2003-08-19 | Astrazeneca Ab | Composicion farmaceutica oral que contiene un copolimero de bloque. |
GB0104752D0 (en) * | 2001-02-27 | 2001-04-18 | Astrazeneca Ab | Pharmaceutical compositions |
WO2003000657A1 (fr) | 2001-06-20 | 2003-01-03 | Daiichi Pharmaceutical Co., Ltd. | Derives de diamine |
ES2543588T3 (es) | 2002-12-03 | 2015-08-20 | Pharmacyclics Llc | Derivados de 2-(2-hidroxibifenil-3-il)-1H-benzoimidazol-5-carboxamidina como inhibidores del factor VIIa |
WO2004108671A1 (en) * | 2003-06-06 | 2004-12-16 | Suven Life Sciences Limited | Substituted indoles with serotonin receptor affinity, process for their preparation and pharmaceutical compositions containing them |
JP4377881B2 (ja) * | 2003-08-01 | 2009-12-02 | 日本曹達株式会社 | フェニルアゾール化合物、製造法および抗酸化薬 |
SE0400014D0 (sv) * | 2004-01-08 | 2004-01-08 | Astrazeneca Ab | Heterocyclic derivatives |
WO2007008144A1 (en) * | 2005-07-08 | 2007-01-18 | Astrazeneca Ab | Heterocyclic sulfonamide derivatives as inhibitors of factor xa |
WO2007008145A1 (en) * | 2005-07-08 | 2007-01-18 | Astrazeneca Ab | Heterocyclic sulfonamide derivatives as inhibitors of factor xa |
WO2007008143A1 (en) * | 2005-07-08 | 2007-01-18 | Astrazeneca Ab | Heterocyclic sulfonamide derivatives as inhibitors of factor xa |
US20080221063A1 (en) * | 2005-07-08 | 2008-09-11 | Astrazeneca Ab | Heterocyclic Sulfonamide Derivatives As Inhibitors Of Factor Xa |
EP3762368B1 (en) | 2018-03-08 | 2022-01-26 | Incyte Corporation | Aminopyrazine diol compounds as pi3k-y inhibitors |
US11046658B2 (en) | 2018-07-02 | 2021-06-29 | Incyte Corporation | Aminopyrazine derivatives as PI3K-γ inhibitors |
WO2021001458A1 (en) | 2019-07-01 | 2021-01-07 | Tonix Pharma Holdings Limited | Anti-cd154 antibodies and uses thereof |
AU2022205313A1 (en) | 2021-01-06 | 2023-07-20 | Tonix Pharma Limited | Methods of inducing immune tolerance with modified anti-cd154 antibodies |
Family Cites Families (8)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
IL115420A0 (en) | 1994-09-26 | 1995-12-31 | Zeneca Ltd | Aminoheterocyclic derivatives |
EP0874629B1 (en) * | 1995-12-21 | 2004-05-19 | Bristol-Myers Squibb Pharma Company | ISOXAZOLINE, ISOTHIAZOLINE AND PYRAZOLINE FACTOR Xa INHIBITORS |
GB9602166D0 (en) * | 1996-02-02 | 1996-04-03 | Zeneca Ltd | Aminoheterocyclic derivatives |
GB9602294D0 (en) * | 1996-02-05 | 1996-04-03 | Zeneca Ltd | Heterocyclic compounds |
UA56197C2 (uk) * | 1996-11-08 | 2003-05-15 | Зенека Лімітед | Гетероциклічні похідні |
ATE334975T1 (de) * | 1997-05-30 | 2006-08-15 | Takeda Pharmaceutical | Sulfonamidderivate, ihre herstellung und verwendung |
GB9715894D0 (en) | 1997-07-29 | 1997-10-01 | Zeneca Ltd | Heterocyclic derivatives |
DE19743435A1 (de) * | 1997-10-01 | 1999-04-08 | Merck Patent Gmbh | Benzamidinderivate |
-
1999
- 1999-04-27 CA CA002331042A patent/CA2331042A1/en not_active Abandoned
- 1999-04-27 DE DE69921994T patent/DE69921994T2/de not_active Expired - Lifetime
- 1999-04-27 NZ NZ507835A patent/NZ507835A/xx unknown
- 1999-04-27 SI SI9930725T patent/SI1082321T1/xx unknown
- 1999-04-27 WO PCT/GB1999/001308 patent/WO1999057113A1/en not_active Application Discontinuation
- 1999-04-27 ES ES99918178T patent/ES2232131T3/es not_active Expired - Lifetime
- 1999-04-27 IL IL13940699A patent/IL139406A/en not_active IP Right Cessation
- 1999-04-27 PL PL99343706A patent/PL343706A1/xx not_active Application Discontinuation
- 1999-04-27 HU HU0101712A patent/HUP0101712A3/hu unknown
- 1999-04-27 PT PT99918178T patent/PT1082321E/pt unknown
- 1999-04-27 AT AT99918178T patent/ATE282610T1/de not_active IP Right Cessation
- 1999-04-27 TR TR2000/03200T patent/TR200003200T2/xx unknown
- 1999-04-27 CN CNB99808218XA patent/CN1133634C/zh not_active Expired - Fee Related
- 1999-04-27 BR BR9910179-3A patent/BR9910179A/pt not_active Application Discontinuation
- 1999-04-27 JP JP2000547083A patent/JP2002513790A/ja active Pending
- 1999-04-27 AU AU36206/99A patent/AU754453B2/en not_active Ceased
- 1999-04-27 KR KR1020007012193A patent/KR20010043246A/ko not_active Application Discontinuation
- 1999-04-27 EP EP99918178A patent/EP1082321B1/en not_active Expired - Lifetime
- 1999-04-27 EP EP04022155A patent/EP1528061A1/en not_active Withdrawn
- 1999-04-27 EE EEP200000527A patent/EE200000527A/et unknown
- 1999-04-27 SK SK1651-2000A patent/SK16512000A3/sk unknown
- 1999-04-27 US US09/674,559 patent/US6753331B1/en not_active Expired - Fee Related
-
2000
- 2000-11-01 NO NO20005497A patent/NO320893B1/no unknown
-
2001
- 2001-07-26 HK HK01105226A patent/HK1034711A1/xx not_active IP Right Cessation
-
2004
- 2004-04-06 US US10/817,960 patent/US20040266759A1/en not_active Abandoned
Also Published As
Publication number | Publication date |
---|---|
ATE282610T1 (de) | 2004-12-15 |
EP1082321B1 (en) | 2004-11-17 |
SI1082321T1 (en) | 2005-06-30 |
EP1528061A1 (en) | 2005-05-04 |
IL139406A (en) | 2004-07-25 |
AU3620699A (en) | 1999-11-23 |
DE69921994T2 (de) | 2005-12-01 |
JP2002513790A (ja) | 2002-05-14 |
US20040266759A1 (en) | 2004-12-30 |
NO320893B1 (no) | 2006-02-06 |
SK16512000A3 (sk) | 2001-05-10 |
AU754453B2 (en) | 2002-11-14 |
BR9910179A (pt) | 2001-01-09 |
CA2331042A1 (en) | 1999-11-11 |
IL139406A0 (en) | 2001-11-25 |
TR200003200T2 (tr) | 2001-02-21 |
ES2232131T3 (es) | 2005-05-16 |
PL343706A1 (en) | 2001-08-27 |
EP1082321A1 (en) | 2001-03-14 |
CN1133634C (zh) | 2004-01-07 |
NZ507835A (en) | 2003-01-31 |
HK1034711A1 (en) | 2001-11-02 |
KR20010043246A (ko) | 2001-05-25 |
HUP0101712A3 (en) | 2003-01-28 |
WO1999057113A1 (en) | 1999-11-11 |
HUP0101712A2 (hu) | 2001-11-28 |
CN1308631A (zh) | 2001-08-15 |
PT1082321E (pt) | 2005-03-31 |
NO20005497D0 (no) | 2000-11-01 |
DE69921994D1 (de) | 2004-12-23 |
US6753331B1 (en) | 2004-06-22 |
NO20005497L (no) | 2000-12-21 |
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