PT1021553E - Cassette de expressao eucariotica de genes e suas utilizacoes - Google Patents
Cassette de expressao eucariotica de genes e suas utilizacoesInfo
- Publication number
- PT1021553E PT1021553E PT98900570T PT98900570T PT1021553E PT 1021553 E PT1021553 E PT 1021553E PT 98900570 T PT98900570 T PT 98900570T PT 98900570 T PT98900570 T PT 98900570T PT 1021553 E PT1021553 E PT 1021553E
- Authority
- PT
- Portugal
- Prior art keywords
- expression
- genes
- cassette
- eucariotica
- herpes simplex
- Prior art date
Links
- 108090000623 proteins and genes Proteins 0.000 title abstract 3
- 241000700584 Simplexvirus Species 0.000 abstract 2
- 230000007774 longterm Effects 0.000 abstract 1
- 210000004962 mammalian cell Anatomy 0.000 abstract 1
- 239000013598 vector Substances 0.000 abstract 1
- 230000007733 viral latency Effects 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
- C12N15/85—Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
- C12N15/86—Viral vectors
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
- A61P25/16—Anti-Parkinson drugs
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/20—Antivirals for DNA viruses
- A61P31/22—Antivirals for DNA viruses for herpes viruses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
- C12N15/85—Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
- A61K2039/525—Virus
- A61K2039/5256—Virus expressing foreign proteins
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K48/00—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2710/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
- C12N2710/00011—Details
- C12N2710/16011—Herpesviridae
- C12N2710/16611—Simplexvirus, e.g. human herpesvirus 1, 2
- C12N2710/16641—Use of virus, viral particle or viral elements as a vector
- C12N2710/16643—Use of virus, viral particle or viral elements as a vector viral genome or elements thereof as genetic vector
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Genetics & Genomics (AREA)
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biomedical Technology (AREA)
- General Health & Medical Sciences (AREA)
- Biotechnology (AREA)
- General Engineering & Computer Science (AREA)
- Wood Science & Technology (AREA)
- Zoology (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Virology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Medicinal Chemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Molecular Biology (AREA)
- Plant Pathology (AREA)
- Microbiology (AREA)
- Biochemistry (AREA)
- Neurology (AREA)
- Physics & Mathematics (AREA)
- Biophysics (AREA)
- Neurosurgery (AREA)
- Heart & Thoracic Surgery (AREA)
- Communicable Diseases (AREA)
- Oncology (AREA)
- Cardiology (AREA)
- Psychology (AREA)
- Ophthalmology & Optometry (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GBGB9700411.3A GB9700411D0 (en) | 1997-01-10 | 1997-01-10 | Eukaryotic gene expression cassette and uses thereof |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| PT1021553E true PT1021553E (pt) | 2004-09-30 |
Family
ID=10805768
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PT98900570T PT1021553E (pt) | 1997-01-10 | 1998-01-12 | Cassette de expressao eucariotica de genes e suas utilizacoes |
Country Status (15)
| Country | Link |
|---|---|
| EP (2) | EP1021553B1 (https=) |
| JP (1) | JP2001508294A (https=) |
| KR (1) | KR100507399B1 (https=) |
| CN (1) | CN1231589C (https=) |
| AT (1) | ATE267263T1 (https=) |
| AU (1) | AU749064B2 (https=) |
| BR (1) | BR9806866A (https=) |
| CA (1) | CA2278326A1 (https=) |
| DE (1) | DE69824027T2 (https=) |
| DK (1) | DK1021553T3 (https=) |
| ES (1) | ES2221980T3 (https=) |
| GB (1) | GB9700411D0 (https=) |
| IL (2) | IL130876A0 (https=) |
| PT (1) | PT1021553E (https=) |
| WO (1) | WO1998030707A2 (https=) |
Families Citing this family (20)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB9801930D0 (en) | 1998-01-29 | 1998-03-25 | Univ London | Mutant herpes simplex viruses and uses thereof |
| GB9807865D0 (en) * | 1998-04-09 | 1998-06-10 | Univ London | Herpes simplex virus latency associated transcript polypeptides |
| US6713067B2 (en) | 1998-07-31 | 2004-03-30 | Biovex Limited | Herpes viruses for immune modulation |
| AU760308B2 (en) * | 1998-07-31 | 2003-05-15 | Cambridge University Technical Services Limited | Latency-active regulatory sequences of herpesviruses and latency-inactive herpesviruses for gene transfer |
| GB9930418D0 (en) | 1999-12-22 | 2000-02-16 | Neurovex Ltd | Replication incompetent herpes virus vectors |
| US7063851B2 (en) | 2000-04-12 | 2006-06-20 | Biovex Limited | Herpes viruses for immune modulation |
| ES2394481T3 (es) | 2000-09-21 | 2013-02-01 | Basf Se | Xilanasa de talaromyces |
| AUPR518501A0 (en) | 2001-05-22 | 2001-06-14 | Unisearch Limited | Yin yang-1 |
| TWI328612B (en) | 2002-07-25 | 2010-08-11 | Dsm Ip Assets Bv | Genes and their encoded polypeptides involved in the biosynthetic pathway of vitamin b12, vectors and host cells comprising the genes, and process for producing vitamin b12 |
| US20050272030A1 (en) * | 2002-09-27 | 2005-12-08 | Powder Ject Research Limited | Nucleic acid constructs for gene expression |
| GB0317511D0 (en) | 2003-07-25 | 2003-08-27 | Biovex Ltd | Viral vectors |
| WO2005080581A2 (en) | 2004-02-17 | 2005-09-01 | University Of Florida Research Foundation, Inc. | Insulated herpesvirus-derived gene expression cassettes for sustained and regulatable gene expression |
| US9593347B2 (en) | 2010-04-16 | 2017-03-14 | University of Pittsburgh—of the Commonwealth System of Higher Education | Identification of mutations in herpes simplex virus envelope glycoproteins that enable or enhance vector retargeting to novel non-HSV receptors |
| JP6726824B2 (ja) * | 2013-07-17 | 2020-07-22 | ユニヴァーシティ オヴ ピッツバーグ オヴ ザ コモンウェルス システム オヴ ハイアー エデュケーション | 効率的な遺伝子送達用途のための非毒性ｈｓｖベクター及びその製造のための補完細胞 |
| CN106068326B (zh) | 2013-10-28 | 2021-06-18 | 联邦高等教育系统-匹兹堡大学 | 溶瘤性hsv载体 |
| EP3778881A1 (en) | 2016-01-08 | 2021-02-17 | Replimune Limited | Modified oncolytic virus |
| RU2749050C2 (ru) | 2016-01-27 | 2021-06-03 | Онкорус, Инк. | Онколитические вирусные векторы и их применение |
| GB201700350D0 (en) * | 2017-01-09 | 2017-02-22 | Replimune Ltd | Altered virus |
| AU2018306455A1 (en) | 2017-07-26 | 2020-02-27 | Virogin Biotech Canada Ltd | Oncolytic viral vectors and uses thereof |
| AU2020284255A1 (en) * | 2019-05-30 | 2022-01-06 | Solid Biosciences Inc. | Recombinant herpesvirales vector |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5849571A (en) * | 1990-10-10 | 1998-12-15 | University Of Pittsburgh Of The Commonwealth System Of Higher Education | Latency active herpes virus promoters and their use |
| PT566554E (pt) * | 1992-03-13 | 2000-09-29 | Monsanto Co | Producao de proteinas recombinantes usando promotores do virus de herpes e transactivadores vp16 |
-
1997
- 1997-01-10 GB GBGB9700411.3A patent/GB9700411D0/en active Pending
-
1998
- 1998-01-12 PT PT98900570T patent/PT1021553E/pt unknown
- 1998-01-12 AU AU55669/98A patent/AU749064B2/en not_active Ceased
- 1998-01-12 JP JP53066398A patent/JP2001508294A/ja not_active Ceased
- 1998-01-12 AT AT98900570T patent/ATE267263T1/de not_active IP Right Cessation
- 1998-01-12 WO PCT/GB1998/000074 patent/WO1998030707A2/en not_active Ceased
- 1998-01-12 CA CA002278326A patent/CA2278326A1/en not_active Abandoned
- 1998-01-12 KR KR10-1999-7006256A patent/KR100507399B1/ko not_active Expired - Fee Related
- 1998-01-12 IL IL13087698A patent/IL130876A0/xx not_active IP Right Cessation
- 1998-01-12 DE DE69824027T patent/DE69824027T2/de not_active Expired - Lifetime
- 1998-01-12 EP EP98900570A patent/EP1021553B1/en not_active Expired - Lifetime
- 1998-01-12 EP EP04008341A patent/EP1441033A3/en not_active Withdrawn
- 1998-01-12 DK DK98900570T patent/DK1021553T3/da active
- 1998-01-12 ES ES98900570T patent/ES2221980T3/es not_active Expired - Lifetime
- 1998-01-12 BR BR9806866-0A patent/BR9806866A/pt not_active Application Discontinuation
- 1998-01-12 CN CNB988032147A patent/CN1231589C/zh not_active Expired - Fee Related
-
1999
- 1999-07-09 IL IL130876A patent/IL130876A/en unknown
Also Published As
| Publication number | Publication date |
|---|---|
| ATE267263T1 (de) | 2004-06-15 |
| ES2221980T3 (es) | 2005-01-16 |
| DE69824027D1 (de) | 2004-06-24 |
| EP1441033A2 (en) | 2004-07-28 |
| AU749064B2 (en) | 2002-06-20 |
| BR9806866A (pt) | 2000-04-18 |
| EP1441033A3 (en) | 2004-12-01 |
| DK1021553T3 (da) | 2004-09-27 |
| JP2001508294A (ja) | 2001-06-26 |
| DE69824027T2 (de) | 2004-10-28 |
| KR100507399B1 (ko) | 2005-08-10 |
| CN1231589C (zh) | 2005-12-14 |
| IL130876A (en) | 2006-08-20 |
| KR20000070037A (ko) | 2000-11-25 |
| CN1250480A (zh) | 2000-04-12 |
| EP1021553A2 (en) | 2000-07-26 |
| AU5566998A (en) | 1998-08-03 |
| WO1998030707A3 (en) | 1998-09-11 |
| IL130876A0 (en) | 2001-01-28 |
| WO1998030707A2 (en) | 1998-07-16 |
| GB9700411D0 (en) | 1997-02-26 |
| CA2278326A1 (en) | 1998-07-16 |
| EP1021553B1 (en) | 2004-05-19 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| PT1021553E (pt) | Cassette de expressao eucariotica de genes e suas utilizacoes | |
| ES2150894T1 (es) | Vector de baculovirus modificado por proteinas de envoltura para terapia genica. | |
| ATE79649T1 (de) | Herpes simplex-virus als vektor. | |
| NO303831B1 (no) | Isolert DNA-sekvens, vektor, vertscelle, polypeptid og anvendelse in vitro av polypeptidet ved en fremgangsmÕte for transfeksjon av hematopoeseceller med eksogen DNA | |
| ZA942778B (en) | Recombinant viruses, and their preparation and use in gene therapy. | |
| AU6149596A (en) | Tumor- or cell-specific herpes simplex virus replication | |
| WO1993024641A3 (en) | Adeno-associated virus with inverted terminal repeat sequences as promoter | |
| AU1851895A (en) | Host-vector system for use in gene therapy | |
| AU3675095A (en) | Use of a non-mammalian dna virus to express an exogenous gene in a mammalian cell | |
| AU2537795A (en) | Transformation systems for the yeast candida utilis and the expression of heterologous genes therewith | |
| FI935459A0 (fi) | Deletionsmutanter av noetkreaturens herpesvirus typ 1, vaccin baserade daerpao; diagnostiska redskap foer upptaeckande av deletionsmutanter av noetkreaturens herpesvirus typ 1 | |
| GB8718779D0 (en) | Dna sequence & expression vector | |
| DE69432901D1 (de) | Expressionssystem von antikörpern bei homologischer rekombinierung in murinezellen | |
| EP0629700A3 (en) | Mammalian vector and cell lines that have increased productivity. | |
| DK0566554T3 (da) | Fremstilling af rekombinante proteiner ved anvendelse af herpesviruspromotorer og VP16-transaktivatorer | |
| WO1999023216A3 (en) | Hyperthermic inducible expression vectors for gene therapy and methods of use thereof | |
| NZ502450A (en) | Recombinant expression of multimeric polypeptide comprising multiple copies of insulin c-peptide | |
| EP0837931A4 (en) | PROCESS FOR THE EXPRESSION AND ISOLATION OF BIOLOGICALLY ACTIVE MOLECULES IN URINE | |
| SI1212428T1 (en) | Cell-specific and/or tumor-specific promoter retargeting of herpes gamma 34.5 gene expression | |
| DK0453969T3 (https=) | ||
| AU582288B2 (en) | Vector and method for achieving high level expression in eukaryotic cells | |
| AU2085195A (en) | Gene coding for igg-fc-binding protein | |
| WO1994006919A3 (en) | Stably-transformed mammalian cells expressing a regulated, inflammatory cyclooxygenase | |
| AU692395B2 (en) | Recombinant herpesvirus with the use of gB gene promoter | |
| WO1997014808A3 (en) | Herpesvirus vectors and their uses |